Chunlei Zheng, PhD
Voluntary Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
General Internal Medicine

PhD, Chinese Academy of Sciences
BS, Shaanxi Normal University

Chunlei Zheng is an Assistant Professor of Medicine at Chobanian and Avedisian School of Medicine. He is also a Health Science Specialist at VA Boston Healthcare System. Dr. Zheng completed his PhD in Biophysics at Chinese Academy of Sciences. After graduation, he moved to Cleveland Clinic, where he received a postdoctoral fellowship from American Heart Association to study the protein trafficking in human diseases. Before joining Boston University, Dr. Zheng is a research scientist at Case Western Reserve University, where he received intensive biomedical informatics training.

With solid background in biology and medicine and expertise in genomics, computer science, and statistics, Dr. Zheng has great passion for data-driven biomedical discovery. In particular, he has great interest on developing/applying computational algorithm, machine learning and statistical modeling into large-scale biomedical data to facilitate disease understanding and drug discovery. Currently, his research focuses on using artificial intelligence (AI) on Alzheimer’s Disease and Cancer.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Placido D, Yuan B, Hjaltelin JX, Zheng C, Haue AD, Chmura PJ, Yuan C, Kim J, Umeton R, Antell G, Chowdhury A, Franz A, Brais L, Andrews E, Marks DS, Regev A, Ayandeh S, Brophy MT, Do NV, Kraft P, Wolpin BM, Rosenthal MH, Fillmore NR, Brunak S, Sander C. A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories. Nat Med. 2023 May; 29(5):1113-1122.View Related Profiles. PMID: 37156936; DOI: 10.1038/s41591-023-02332-5;
  2. Li LL, Zheng C, La J, Do NV, Monach PA, Strymish JM, Fillmore NR, Branch-Elliman W. Impact of prior SARS-CoV-2 infection on incidence of hospitalization and adverse events following mRNA SARS-CoV-2 vaccination: A nationwide, retrospective cohort study. Vaccine. 2022 02 16; 40(8):1082-1089.View Related Profiles. PMID: 35078665; PMCID: PMC8768509; DOI: 10.1016/j.vaccine.2022.01.026;
  3. Fillmore NR, La J, Zheng C, Doron S, Do NV, Monach PA, Branch-Elliman W. The COVID-19 hospitalization metric in the pre- and postvaccination eras as a measure of pandemic severity: A retrospective, nationwide cohort study. Infect Control Hosp Epidemiol. 2022 Dec; 43(12):1767-1772.View Related Profiles. PMID: 35012694; PMCID: PMC9021586; DOI: 10.1017/ice.2022.13;
  4. Zheng C, Fillmore NR, Ramos-Cejudo J, Brophy M, Osorio R, Gurney ME, Qiu WQ, Au R, Perry G, Dubreuil M, Chen SG, Qi X, Davis PB, Do N, Xu R. Potential long-term effect of tumor necrosis factor inhibitors on dementia risk: A propensity score matched retrospective cohort study in US veterans. Alzheimers Dement. 2022 Jun; 18(6):1248-1259.View Related Profiles. PMID: 34569707; PMCID: PMC8957621; DOI: 10.1002/alz.12465;
  5. Zheng C, Xu R. Molecular subtyping of Alzheimer's disease with consensus non-negative matrix factorization. PLoS One. 2021; 16(5):e0250278. PMID: 34014928; PMCID: PMC8136734; DOI: 10.1371/journal.pone.0250278;
  6. Wang Q, Li Y, Zheng C, Xu R. DenseCNN: A Densely Connected CNN Model for Alzheimer's Disease Classification Based on Hippocampus MRI Data. AMIA Annu Symp Proc. 2020; 2020:1277-1286. PMID: 33936504; PMCID: PMC8075423
  7. Zhou M, Wang Q, Zheng C, John Rush A, Volkow ND, Xu R. Drug repurposing for opioid use disorders: integration of computational prediction, clinical corroboration, and mechanism of action analyses. Mol Psychiatry. 2021 09; 26(9):5286-5296. PMID: 33432189; PMCID: PMC7797705; DOI: 10.1038/s41380-020-01011-y;
  8. Zheng C, Berger NA, Li L, Xu R. Epigenetic age acceleration and clinical outcomes in gliomas. PLoS One. 2020; 15(7):e0236045. PMID: 32692766; PMCID: PMC7373289; DOI: 10.1371/journal.pone.0236045;
  9. Zhou M, Zheng C, Xu R. Combining phenome-driven drug-target interaction prediction with patients' electronic health records-based clinical corroboration toward drug discovery. Bioinformatics. 2020 07 01; 36(Suppl_1):i436-i444. PMID: 32657406; PMCID: PMC7355254; DOI: 10.1093/bioinformatics/btaa451;
  10. Zheng C, Xu R. Predicting cancer origins with a DNA methylation-based deep neural network model. PLoS One. 2020; 15(5):e0226461. PMID: 32384093; PMCID: PMC7209244; DOI: 10.1371/journal.pone.0226461;
Showing 10 of 30 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 30 publications over 15 distinct years, with a maximum of 4 publications in 2020 and 2021


2010-2012 American Heart Association: Postdoctoral fellowship
2010 51st American Society Cell Biology annual meeting, Philadelphia, PA: Travel award for poster presentation
2009 50th American Society of Hematology annual meeting, New Orleans, LA: Travel award for poster presentation
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Artificial Intelligence
Statistical Model
Alzheimer's Disease
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