Chunlei Zheng, PhD
Assistant Professor
Boston University School of Medicine
Dept of Medicine
General Internal Medicine

Chunlei Zheng is an Assistant Professor of Medicine at Boston University School of Medicine. He is also a Health Science Specialist at VA Boston Healthcare System. Dr. Zheng completed his PhD in Biophysics at Chinese Academy of Sciences. After graduation, he moved to Cleveland Clinic, where he received a postdoctoral fellowship from American Heart Association to study the protein trafficking in human diseases. Before joining Boston University, Dr. Zheng is a research scientist at Case Western Reserve University, where he received intensive biomedical informatics training.

With solid background in biology and medicine and expertise in genomics, computer science, and statistics, Dr. Zheng has great passion for data-driven biomedical discovery. In particular, he has great interest on developing/applying computational algorithm, machine learning and statistical modeling into large-scale biomedical data to facilitate disease understanding and drug discovery. Currently, his research focuses on using artificial intelligence (AI) on Alzheimer’s Disease and Cancer.

2010-2012 American Heart Association: Postdoctoral fellowship
2010 51st American Society Cell Biology annual meeting, Philadelphia, PA: Travel award for poster presentation
2009 50th American Society of Hematology annual meeting, New Orleans, LA: Travel award for poster presentation

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Zheng C, Fillmore NR, Ramos-Cejudo J, Brophy M, Osorio R, Gurney ME, Qiu WQ, Au R, Perry G, Dubreuil M, Chen SG, Qi X, Davis PB, Do N, Xu R. Potential long-term effect of tumor necrosis factor inhibitors on dementia risk: A propensity score matched retrospective cohort study in US veterans. Alzheimers Dement. 2021 Sep 27.View Related Profiles. PMID: 34569707
  2. Zheng C, Xu R. Molecular subtyping of Alzheimer's disease with consensus non-negative matrix factorization. PLoS One. 2021; 16(5):e0250278. PMID: 34014928; PMCID: PMC8136734; DOI: 10.1371/journal.pone.0250278;
  3. Wang Q, Li Y, Zheng C, Xu R. DenseCNN: A Densely Connected CNN Model for Alzheimer's Disease Classification Based on Hippocampus MRI Data. AMIA Annu Symp Proc. 2020; 2020:1277-1286. PMID: 33936504; PMCID: PMC8075423
  4. Zhou M, Wang Q, Zheng C, John Rush A, Volkow ND, Xu R. Drug repurposing for opioid use disorders: integration of computational prediction, clinical corroboration, and mechanism of action analyses. Mol Psychiatry. 2021 Sep; 26(9):5286-5296. PMID: 33432189; PMCID: PMC7797705; DOI: 10.1038/s41380-020-01011-y;
  5. Zheng C, Berger NA, Li L, Xu R. Epigenetic age acceleration and clinical outcomes in gliomas. PLoS One. 2020; 15(7):e0236045. PMID: 32692766; PMCID: PMC7373289; DOI: 10.1371/journal.pone.0236045;
  6. Zhou M, Zheng C, Xu R. Combining phenome-driven drug-target interaction prediction with patients' electronic health records-based clinical corroboration toward drug discovery. Bioinformatics. 2020 07 01; 36(Suppl_1):i436-i444. PMID: 32657406; PMCID: PMC7355254; DOI: 10.1093/bioinformatics/btaa451;
  7. Zheng C, Xu R. Predicting cancer origins with a DNA methylation-based deep neural network model. PLoS One. 2020; 15(5):e0226461. PMID: 32384093; PMCID: PMC7209244; DOI: 10.1371/journal.pone.0226461;
  8. Conic RR, Damiani G, Schrom KP, Ramser AE, Zheng C, Xu R, McCormick TS, Cooper KD. Psoriasis and Psoriatic Arthritis Cardiovascular Disease Endotypes Identified by Red Blood Cell Distribution Width and Mean Platelet Volume. J Clin Med. 2020 Jan 09; 9(1). PMID: 31936662; PMCID: PMC7019311; DOI: 10.3390/jcm9010186;
  9. Zheng C, Li L, Xu R. Association of Epigenetic Clock with Consensus Molecular Subtypes and Overall Survival of Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2019 10; 28(10):1720-1724. PMID: 31375479; PMCID: PMC6774810; DOI: 10.1158/1055-9965.EPI-19-0208;
  10. Luo L, Zheng C, Wang J, Tan M, Li Y, Xu R. Analysis of disease organ as a novel phenotype towards disease genetics understanding. J Biomed Inform. 2019 07; 95:103235. PMID: 31207382; PMCID: PMC6644057; DOI: 10.1016/j.jbi.2019.103235;
Showing 10 of 27 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 27 publications over 13 distinct years, with a maximum of 4 publications in 2020 and 2021


In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Artificial Intelligence
Statistical Model
Alzheimer's Disease
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