Chia-Ling Wu | Profiles RNS

Chia-Ling Wu, PhD

Scientist

Sarepta Therapeutics

Websites

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	ResearchGate

PhD Molecular biologist with 7+years industrial experiences in neuromuscular, autoimmune and rare diseases. Experience working across various stages of drug discovery and development processes including in vitro and in vivo pharmacology, assay development, drug screening and advancement from Hit ID through pre-clinical and clinical development. Strong knowledge in RNA therapeutics, small molecule drug and AAV-based gene therapy. Effective communication skills with a track record of collaborating with cross-functional teams

Postdoctoral Fellow (Previously held)
Boston University Chobanian & Avedisian School of Medicine
Cardiovascular Institute (Whitaker)

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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Nhu NT, Kang JH, Yeh TS, Chang JH, Tzeng YT, Chan TC, Wu CC, Lam C. Predicting 14-day readmission in middle-aged and elderly patients with pneumonia using emergency department data: a multicentre retrospective cohort study with a survival machine learning approach. BMJ Open. 2025 Jun 17; 15(6):e102711. PMID: 40527577; PMCID: PMC12182127; DOI: 10.1136/bmjopen-2025-102711;

Fang YT, Liao SF, Chen PL, Yeh TS, Chen CI, Piravej K, Wu CC, Chiu WT, Lam C. Risk of Traumatic Intracranial Hemorrhage After Stroke: A Nationwide Population-Based Cohort Study in Taiwan. J Am Heart Assoc. 2024 Oct; 13(19):e035725. PMID: 39291491; PMCID: PMC11681476; DOI: 10.1161/JAHA.124.035725;

Yeh TS, Kang JH, Littlejohns TJ, Wu CC, Chen JH, Piravej K, Chiu WT, Lam C. Frailty and Other Factors Associated With Early Outcomes in Middle-to Older Age Trauma Patients: A Prospective Cohort Study. Am J Geriatr Psychiatry. 2024 Feb; 32(2):244-255. PMID: 37770348

Maruyama S, Wu CL, Yoshida S, Zhang D, Li PH, Wu F, Parker Duffen J, Yao R, Jardin B, Adham IM, Law R, Berger J, Di Marchi R, Walsh K. Relaxin Family Member Insulin-Like Peptide 6 Ameliorates Cardiac Fibrosis and Prevents Cardiac Remodeling in Murine Heart Failure Models. J Am Heart Assoc. 2018 06 10; 7(12).View Related Profiles.

Wu, Chia-Ling
Walsh, Kenneth
Maruyama, Sonomi

PMID: 29887522; PMCID: PMC6220528; DOI: 10.1161/JAHA.117.008441;

Seki M, Powers JC, Maruyama S, Zuriaga MA, Wu CL, Kurishima C, Kim L, Johnson J, Poidomani A, Wang T, Muñoz E, Rajan S, Park JY, Walsh K, Recchia FA. Acute and Chronic Increases of Circulating FSTL1 Normalize Energy Substrate Metabolism in Pacing-Induced Heart Failure. Circ Heart Fail. 2018 01; 11(1):e004486.View Related Profiles.

Wu, Chia-Ling
Park, Joongheum
Walsh, Kenneth
Zuriaga Herrero, Maria
Maruyama, Sonomi

PMID: 29317401; PMCID: PMC5765881; DOI: 10.1161/CIRCHEARTFAILURE.117.004486;

Neppl RL, Wu CL, Walsh K. lncRNA Chronos is an aging-induced inhibitor of muscle hypertrophy. J Cell Biol. 2017 Nov 06; 216(11):3497-3507.View Related Profiles.

Wu, Chia-Ling
Walsh, Kenneth

PMID: 28855249; PMCID: PMC5674882; DOI: 10.1083/jcb.201612100;

Wu CL, Satomi Y, Walsh K. RNA-seq and metabolomic analyses of Akt1-mediated muscle growth reveals regulation of regenerative pathways and changes in the muscle secretome. BMC Genomics. 2017 Feb 16; 18(1):181.View Related Profiles.

Wu, Chia-Ling
Walsh, Kenneth

PMID: 28209124; PMCID: PMC5314613; DOI: 10.1186/s12864-017-3548-2;

Fuster JJ, MacLauchlan S, Zuriaga MA, Polackal MN, Ostriker AC, Chakraborty R, Wu CL, Sano S, Muralidharan S, Rius C, Vuong J, Jacob S, Muralidhar V, Robertson AA, Cooper MA, Andrés V, Hirschi KK, Martin KA, Walsh K. Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice. Science. 2017 02 24; 355(6327):842-847.View Related Profiles.

Wu, Chia-Ling
Fuster Ortuno, Jose
Walsh, Kenneth
Zuriaga Herrero, Maria
Maclauchlan, Susan

PMID: 28104796; PMCID: PMC5542057; DOI: 10.1126/science.aag1381;

Peng YJ, Huang JJ, Wu HH, Hsieh HY, Wu CY, Chen SC, Chen TY, Tang CY. Regulation of CLC-1 chloride channel biosynthesis by FKBP8 and Hsp90ß. Sci Rep. 2016 09 01; 6:32444. PMID: 27580824

Judge SM, Wu CL, Beharry AW, Roberts BM, Ferreira LF, Kandarian SC, Judge AR. Genome-wide identification of FoxO-dependent gene networks in skeletal muscle during C26 cancer cachexia. BMC Cancer. 2014 Dec 24; 14:997. PMID: 25539728; PMCID: PMC4391468; DOI: 10.1186/1471-2407-14-997;

Showing 10 of 18 results. Show More

Wu CL, Cornwell EW, Jackman RW, Kandarian SC. NF-?B but not FoxO sites in the MuRF1 promoter are required for transcriptional activation in disuse muscle atrophy. Am J Physiol Cell Physiol. 2014 Apr 15; 306(8):C762-7. PMID: 24553183; PMCID: PMC3989716; DOI: 10.1152/ajpcell.00361.2013;

Cornwell EW, Mirbod A, Wu CL, Kandarian SC, Jackman RW. C26 cancer-induced muscle wasting is IKKß-dependent and NF-kappaB-independent. PLoS One. 2014; 9(1):e87776. PMID: 24489962; PMCID: PMC3906224; DOI: 10.1371/journal.pone.0087776;

Jackman RW, Wu CL, Kandarian SC. The ChIP-seq-defined networks of Bcl-3 gene binding support its required role in skeletal muscle atrophy. PLoS One. 2012; 7(12):e51478. PMID: 23251550; PMCID: PMC3519692; DOI: 10.1371/journal.pone.0051478;

Jackman RW, Cornwell EW, Wu CL, Kandarian SC. Nuclear factor-?B signalling and transcriptional regulation in skeletal muscle atrophy. Exp Physiol. 2013 Jan; 98(1):19-24. PMID: 22848079; PMCID: PMC3505235; DOI: 10.1113/expphysiol.2011.063321;

Yamaki T, Wu CL, Gustin M, Lim J, Jackman RW, Kandarian SC. Rel A/p65 is required for cytokine-induced myotube atrophy. Am J Physiol Cell Physiol. 2012 Jul 15; 303(2):C135-42.View Related Profiles.

Wu, Chia-Ling
Lim, Jamie

PMID: 22592403; PMCID: PMC3404521; DOI: 10.1152/ajpcell.00111.2012;

Wu CL, Kandarian SC. Protein overexpression in skeletal muscle using plasmid-based gene transfer to elucidate mechanisms controlling fiber size. Methods Mol Biol. 2012; 798:231-43. PMID: 22130840; DOI: 10.1007/978-1-61779-343-1_13;

Kielbasa OM, Reynolds JG, Wu CL, Snyder CM, Cho MY, Weiler H, Kandarian S, Naya FJ. Myospryn is a calcineurin-interacting protein that negatively modulates slow-fiber-type transformation and skeletal muscle regeneration. FASEB J. 2011 Jul; 25(7):2276-86.View Related Profiles.

Wu, Chia-Ling
Naya, Francisco

PMID: 21427212; PMCID: PMC3114531; DOI: 10.1096/fj.10-169219;

Wu CL, Kandarian SC, Jackman RW. Identification of genes that elicit disuse muscle atrophy via the transcription factors p50 and Bcl-3. PLoS One. 2011 Jan 13; 6(1):e16171. PMID: 21249144; PMCID: PMC3020958; DOI: 10.1371/journal.pone.0016171;

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 18 publications over 9 distinct years, with a maximum of 4 publications in 2012

Bar chart showing 18 publications over 9 distinct years, with a maximum of 4 publications in 2012

Year	Publications
2011	2
2012	4
2014	3
2016	1
2017	3
2018	2
2023	1
2024	1
2025	1

Contact for Mentoring:

700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
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617.414.2390

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