Catherine Valentine, MD
Assistant Professor
Boston University School of Medicine
Dept of Medicine
Pulmonary, Allergy, Sleep & Critical Care Medicine

MD, New York University School of Medicine

Clinical Expertise-Critical care medicine, with a focus on the management of sepsis and severe infections in the ICU.

Research Expertise-Sepsis, with a focus on interactions between the host innate and adaptive immune responses.

Assistant Professor
Boston University School of Medicine
Pathology & Laboratory Medicine

Adenosine and TLR Regulation of Costimulatory Molecular Expression in Sepsis
02/01/2016 - 09/30/2017 (PI)
NIH/National Institute of General Medical Sciences

Adenosine and TLR regulation of costimulatory molecule expression in sepsis
02/01/2012 - 01/31/2016 (PI)
NIH/National Institutes of Health

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Iskander KN, Osuchowski MF, Stearns-Kurosawa DJ, Kurosawa S, Stepien D, Valentine C, Remick DG. Sepsis: multiple abnormalities, heterogeneous responses, and evolving understanding. Physiol Rev. 2013 Jul; 93(3):1247-88.View Related Profiles. PMID: 23899564; DOI: 10.1152/physrev.00037.2012;.
  2. Stearns-Kurosawa DJ, Osuchowski MF, Valentine C, Kurosawa S, Remick DG. The pathogenesis of sepsis. Annu Rev Pathol. 2011; 6:19-48.View Related Profiles. PMID: 20887193; PMCID: PMC3684427; DOI: 10.1146/annurev-pathol-011110-130327;.
  3. Shin HS, Xu F, Bagchi A, Herrup E, Prakash A, Valentine C, Kulkarni H, Wilhelmsen K, Warren S, Hellman J. Bacterial lipoprotein TLR2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo. J Immunol. 2011 Jan 15; 186(2):1119-30. PMID: 21169547; PMCID: PMC3482611; DOI: 10.4049/jimmunol.1001647;.
  4. Warren HS, Fitting C, Hoff E, Adib-Conquy M, Beasley-Topliffe L, Tesini B, Liang X, Valentine C, Hellman J, Hayden D, Cavaillon JM. Resilience to bacterial infection: difference between species could be due to proteins in serum. J Infect Dis. 2010 Jan 15; 201(2):223-32. PMID: 20001600; PMCID: PMC2798011; DOI: 10.1086/649557;.
  5. Bagchi A, Herrup EA, Warren HS, Trigilio J, Shin HS, Valentine C, Hellman J. MyD88-dependent and MyD88-independent pathways in synergy, priming, and tolerance between TLR agonists. J Immunol. 2007 Jan 15; 178(2):1164-71. PMID: 17202381.
  6. Valentine CH, Hellman J, Beasley-Topliffe LK, Bagchi A, Warren HS. Passive immunization to outer membrane proteins MLP and PAL does not protect mice from sepsis. Mol Med. 2006 Sep-Oct; 12(9-10):252-8. PMID: 17225874; PMCID: PMC1770012.
  7. Valentine CH, Hellman J. General Considerations in Infectious Disease. In: Critical Care Handbook of the Massachusetts General Hospital. Senior ed: Luca Bigatello. Lippincott Williams & Wilkins. Phildelphia, PA. 2005; 212-231.
  8. Johnson MR, Valentine C, Basilico C, Mansukhani A. FGF signaling activates STAT1 and p21 and inhibits the estrogen response and proliferation of MCF-7 cells. Oncogene. 1998 May; 16(20):2647-56. PMID: 9632141; DOI: 10.1038/sj.onc.1201789;.

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 8 publications over 7 distinct years, with a maximum of 2 publications in 2010

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Contact for Mentoring:

670 Albany St Biosquare III
Boston MA 02118
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