Vyacheslav Labunskyy, PhD
|Institution||Boston University School of Medicine|
|Address||609 Albany Street|
Boston MA 02118
The primary research focus of our lab is the biology of aging and understanding the basic mechanisms that underlie the pathogenesis of age-related diseases. We are particularly interested in studying the nature of senescence factors and understanding how stress response signaling regulates aging. In our work we utilize ribosome profiling and next-generation sequencing, and a combination of molecular and biochemical approaches to look at transcriptional and translational changes that are associated with the aging process as well as the mechanisms of such regulation in eukaryotic cells. A second major focus of the laboratory is synthetic biology and developing new bioengineering approaches that can be used to study complex traits, such as longevity, using yeast S. cerevisiae as a model organism.
We hope that our studies will provide a better understanding of the mechanisms that regulate aging and will help to identify new targets for therapeutic intervention for age-related diseases.
- Molecular Mechanisms of Skin Aging
- Functional Genomics
- Stress Signaling
- Synthetic Biology