Keywords
Last Name

Edward Jones Lopez, MD

TitleAssistant Professor
InstitutionBoston University School of Medicine
DepartmentMedicine
DivisionInfectious Diseases
Address771 Albany St
Boston MA 02118
Phone(617) 414-5247
ORCID ORCID Icon0000-0001-6323-286X
Other Positions
TitleAssistant Professor
InstitutionBoston University School of Public Health
DepartmentEpidemiology

InstitutionBoston Medical Center

 Research Expertise & Professional Interests
Dr. Edward C. Jones López is trained in infectious diseases and epidemiology and has extensive experience in the design, implementation and oversight of large, international collaborative research projects. Focused on translational science, over the last decade Dr. Jones has participated as principal investigator or co-investigator in several clinical studies in tuberculosis (TB) and HIV, and has made a number of contributions to the understanding of TB in human populations. Fluent in Spanish, French and Portuguese, Dr. Jones has lived and worked for extended periods of time in under-resourced settings providing him with a unique ability to work effectively in cross-cultural settings and pursue his longstanding interest in TB, HIV/AIDS and global health issues. Dr. Jones is particularly interested in applying epidemiologic methods to understand the determinants of TB transmission, infection and disease, using a multidisciplinary research approach.

 Self-Described Keywords
  • Global health
  • HIV/AIDS
  • Tuberculosis
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. de la Fuente J, Díez-Delgado I, Contreras M, Vicente J, Cabezas-Cruz A, Tobes R, Manrique M, López V, Romero B, Bezos J, Dominguez L, Sevilla IA, Garrido JM, Juste R, Madico G, Jones-López E, Gortazar C. Comparative Genomics of Field Isolates of Mycobacterium bovis and M. caprae Provides Evidence for Possible Correlates with Bacterial Viability and Virulence. PLoS Negl Trop Dis. 2015 Nov; 9(11):e0004232. PMID: 26583774.
    View in: PubMed
  2. Fennelly KP, Jones-López EC. Corrigendum: Quantity and Quality of Inhaled Dose Predicts Immunopathology in Tuberculosis. Front Immunol. 2015; 6:511. PMID: 26483797.
    View in: PubMed
  3. Jones-López EC, White LF, Kirenga B, Mumbowa F, Ssebidandi M, Moine S, Mbabazi O, Mboowa G, Ayakaka I, Kim S, Thornton CS, Okwera A, Joloba M, Fennelly KP. Cough Aerosol Cultures of Mycobacterium tuberculosis: Insights on TST / IGRA Discordance and Transmission Dynamics. PLoS One. 2015; 10(9):e0138358. PMID: 26394149.
    View in: PubMed
  4. Fennelly KP, Jones-López EC. Quantity and Quality of Inhaled Dose Predicts Immunopathology in Tuberculosis. Front Immunol. 2015; 6:313. PMID: 26175730.
    View in: PubMed
  5. Salgame P, Geadas C, Collins L, Jones-López E, Ellner JJ. Latent tuberculosis infection--Revisiting and revising concepts. Tuberculosis (Edinb). 2015 Jul; 95(4):373-84. PMID: 26038289.
    View in: PubMed
  6. Acuña-Villaorduña C, Ayakaka I, Dryden-Peterson S, Nakubulwa S, Worodria W, Reilly N, Hosford J, Fennelly KP, Okwera A, Jones-López EC. High mortality associated with retreatment of tuberculosis in a clinic in Kampala, Uganda: a retrospective study. Am J Trop Med Hyg. 2015 Jul; 93(1):73-5. PMID: 25940196.
    View in: PubMed
  7. Jones-López EC, Kim S, Fregona G, Marques-Rodrigues P, Hadad DJ, Molina LP, Vinhas S, Reilly N, Moine S, Chakravorty S, Gaeddert M, Ribeiro-Rodrigues R, Salgame P, Palaci M, Alland D, Ellner JJ, Dietze R. Importance of cough and M. tuberculosis strain type as risks for increased transmission within households. PLoS One. 2014; 9(7):e100984. PMID: 24988000.
    View in: PubMed
  8. Ribeiro-Rodrigues R, Kim S, Coelho da Silva FD, Uzelac A, Collins L, Palaci M, Alland D, Dietze R, Ellner JJ, Jones-López E, Salgame P. Discordance of tuberculin skin test and interferon gamma release assay in recently exposed household contacts of pulmonary TB cases in Brazil. PLoS One. 2014; 9(5):e96564. PMID: 24819060.
    View in: PubMed
  9. Jones-López E, Manabe YC, Palaci M, Kayiza C, Armstrong D, Nakiyingi L, Ssengooba W, Gaeddert M, Kubiak R, Almeida Júnior P, Alland D, Dietze R, Joloba M, Ellner JJ, Dorman SE. Prospective cross-sectional evaluation of the small membrane filtration method for diagnosis of pulmonary tuberculosis. J Clin Microbiol. 2014 Jul; 52(7):2513-20. PMID: 24808236.
    View in: PubMed
  10. Kirenga BJ, Levin J, Ayakaka I, Worodria W, Reilly N, Mumbowa F, Nabanjja H, Nyakoojo G, Fennelly K, Nakubulwa S, Joloba M, Okwera A, Eisenach KD, McNerney R, Elliott AM, Mugerwa RD, Smith PG, Ellner JJ, Jones-López EC. Treatment outcomes of new tuberculosis patients hospitalized in Kampala, Uganda: a prospective cohort study. PLoS One. 2014; 9(3):e90614. PMID: 24608875.
    View in: PubMed
  11. Clark TG, Mallard K, Coll F, Preston M, Assefa S, Harris D, Ogwang S, Mumbowa F, Kirenga B, O'Sullivan DM, Okwera A, Eisenach KD, Joloba M, Bentley SD, Ellner JJ, Parkhill J, Jones-López EC, McNerney R. Elucidating emergence and transmission of multidrug-resistant tuberculosis in treatment experienced patients by whole genome sequencing. PLoS One. 2013; 8(12):e83012. PMID: 24349420.
    View in: PubMed
  12. Jones-López EC, Namugga O, Mumbowa F, Ssebidandi M, Mbabazi O, Moine S, Mboowa G, Fox MP, Reilly N, Ayakaka I, Kim S, Okwera A, Joloba M, Fennelly KP. Cough aerosols of Mycobacterium tuberculosis predict new infection: a household contact study. Am J Respir Crit Care Med. 2013 May 1; 187(9):1007-15. PMID: 23306539.
    View in: PubMed
  13. Fennelly KP, Jones-López EC, Ayakaka I, Kim S, Menyha H, Kirenga B, Muchwa C, Joloba M, Dryden-Peterson S, Reilly N, Okwera A, Elliott AM, Smith PG, Mugerwa RD, Eisenach KD, Ellner JJ. Variability of infectious aerosols produced during coughing by patients with pulmonary tuberculosis. Am J Respir Crit Care Med. 2012 Sep 1; 186(5):450-7. PMID: 22798319.
    View in: PubMed
  14. Jones-López EC, Ayakaka I, Levin J, Reilly N, Mumbowa F, Dryden-Peterson S, Nyakoojo G, Fennelly K, Temple B, Nakubulwa S, Joloba ML, Okwera A, Eisenach KD, McNerney R, Elliott AM, Ellner JJ, Smith PG, Mugerwa RD. Effectiveness of the standard WHO recommended retreatment regimen (category II) for tuberculosis in Kampala, Uganda: a prospective cohort study. PLoS Med. 2011 Mar; 8(3):e1000427. PMID: 21423586.
    View in: PubMed
  15. Gatell JM, Katlama C, Grinsztejn B, Eron JJ, Lazzarin A, Vittecoq D, Gonzalez CJ, Danovich RM, Wan H, Zhao J, Meibohm AR, Strohmaier KM, Harvey CM, Isaacs RD, Nguyen BY. Long-term efficacy and safety of the HIV integrase inhibitor raltegravir in patients with limited treatment options in a Phase II study. J Acquir Immune Defic Syndr. 2010 Apr 1; 53(4):456-63. PMID: 20306554.
    View in: PubMed
  16. Motiwala AS, Dai Y, Jones-López EC, Hwang SH, Lee JS, Cho SN, Via LE, Barry CE, Alland D. Mutations in extensively drug-resistant Mycobacterium tuberculosis that do not code for known drug-resistance mechanisms. J Infect Dis. 2010 Mar 15; 201(6):881-8. PMID: 20136412.
    View in: PubMed
  17. Helb D, Jones M, Story E, Boehme C, Wallace E, Ho K, Kop J, Owens MR, Rodgers R, Banada P, Safi H, Blakemore R, Lan NT, Jones-López EC, Levi M, Burday M, Ayakaka I, Mugerwa RD, McMillan B, Winn-Deen E, Christel L, Dailey P, Perkins MD, Persing DH, Alland D. Rapid detection of Mycobacterium tuberculosis and rifampin resistance by use of on-demand, near-patient technology. J Clin Microbiol. 2010 Jan; 48(1):229-37. PMID: 19864480.
    View in: PubMed
  18. Ogwang S, Asiimwe BB, Traore H, Mumbowa F, Okwera A, Eisenach KD, Kayes S, Jones-López EC, McNerney R, Worodria W, Ayakaka I, Mugerwa RD, Smith PG, Ellner J, Joloba ML. Comparison of rapid tests for detection of rifampicin-resistant Mycobacterium tuberculosis in Kampala, Uganda. BMC Infect Dis. 2009; 9:139. PMID: 19709423.
    View in: PubMed
  19. Temple B, Ayakaka I, Ogwang S, Nabanjja H, Kayes S, Nakubulwa S, Worodria W, Levin J, Joloba M, Okwera A, Eisenach KD, McNerney R, Elliott AM, Smith PG, Mugerwa RD, Ellner JJ, Jones-López EC. Rate and amplification of drug resistance among previously-treated patients with tuberculosis in Kampala, Uganda. Clin Infect Dis. 2008 Nov 1; 47(9):1126-34. PMID: 18808360.
    View in: PubMed
  20. Colebunders R, Worodria W, Jones-López E, Joloba M, Apers L, Ellner J. Drug-resistant TB and HIV in resource-limited settings: what TB/HIV programmes can learn from each other. Trop Med Int Health. 2008 Sep; 13(9):1204-7. PMID: 18664238.
    View in: PubMed
  21. Traore H, Ogwang S, Mallard K, Joloba ML, Mumbowa F, Narayan K, Kayes S, Jones-Lopez EC, Smith PG, Ellner JJ, Mugerwa RD, Eisenach KD, McNerney R. Low-cost rapid detection of rifampicin resistant tuberculosis using bacteriophage in Kampala, Uganda. Ann Clin Microbiol Antimicrob. 2007; 6:1. PMID: 17212825.
    View in: PubMed
  22. Whalen CC, Chiunda A, Zalwango S, Nshuti L, Jones-Lopez E, Okwera A, Hirsch C, Peters P, Boom WH, Mugerwa RD. Immune correlates of acute Mycobacterium tuberculosis infection in household contacts in Kampala, Uganda. Am J Trop Med Hyg. 2006 Jul; 75(1):55-61. PMID: 16837709.
    View in: PubMed
  23. Jones-López EC, Okwera A, Mayanja-Kizza H, Ellner JJ, Mugerwa RD, Whalen CC. Delayed-type hypersensitivity skin test reactivity and survival in HIV-infected patients in Uganda: should anergy be a criterion to start antiretroviral therapy in low-income countries? Am J Trop Med Hyg. 2006 Jan; 74(1):154-61. PMID: 16407361.
    View in: PubMed
  24. Jones-Lopez EC, Ellner JJ, Whalen CC. Subclinical tuberculosis: a new entity? Clin Infect Dis. 2005 Oct 1; 41(7):1069-70; author reply 1070-1. PMID: 16142680.
    View in: PubMed
  25. Jones-López EC, Ellner JJ. Tuberculosis infection among HCWs. Int J Tuberc Lung Dis. 2005 Jun; 9(6):591. PMID: 15971384.
    View in: PubMed
  26. Mayanja-Kizza H, Jones-Lopez E, Okwera A, Wallis RS, Ellner JJ, Mugerwa RD, Whalen CC. Immunoadjuvant prednisolone therapy for HIV-associated tuberculosis: a phase 2 clinical trial in Uganda. J Infect Dis. 2005 Mar 15; 191(6):856-65. PMID: 15717259.
    View in: PubMed
  27. Guwatudde D, Nakakeeto M, Jones-Lopez EC, Maganda A, Chiunda A, Mugerwa RD, Ellner JJ, Bukenya G, Whalen CC. Tuberculosis in household contacts of infectious cases in Kampala, Uganda. Am J Epidemiol. 2003 Nov 1; 158(9):887-98. PMID: 14585767.
    View in: PubMed
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