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Research Expertise & Professional Interests Ralph B. D’Agostino, Sr., is Chairman of the Mathematics and Statistics Department and Professor of Mathematics/Statistics, Biostatistics and Epidemiology at Boston University (Ph.D., Harvard, 1968). His major fields of research are clinical trials, epidemiology, prognostics models, longitudinal analysis, multivariate analysis, robustness, and outcomes/effectiveness research. He has extensive experience (since the 1980’s) developing cardiovascular risk prediction models which have been used in Treatment Guidelines sponsored by the NIH and American Heart Association and also web based models for general consumer use. He is a fellow of the American Statistical Association and the Cardiovascular Epidemiology Council of the American Heart Association. He has been with the Framingham Heart Study since 1981 and is Co-Principal Investigator of the Core contract and Director of Data Management and Statistical Analysis for the study. He is a Special Government Employee (SGE) to the United States’ Food and Drug Administration (FDA). He has been affiliated with the FDA’s Center for Drugs Evaluation and Research (CDER) since 1974 as an Expert Consultant to the Biometrics Division, the Over-the-Counter Drugs Division, the Oncology Drugs Division, the Cardiovascular-Renal Drugs Division and the Gastrointestinal Drugs Division. He has also been a consultant to the Device Division. Further, he has served on a number of Advisory Committees and was the Chair of the Nonprescription Drugs Advisory Committee (NDAC). He has twice been the recipient of the FDA’s Commissioner’s Special Citation (1981 and 1995).

One or more keywords matched the following items that are connected to D'Agostino, Ralph

Item TypeName
Concept Acute Disease
Concept Alzheimer Disease
Concept Aortic Diseases
Concept Auditory Diseases, Central
Concept Autonomic Nervous System Diseases
Concept Cardiovascular Diseases
Concept Carotid Artery Diseases
Concept Chronic Disease
Concept Clostridium Infections
Concept Coronary Artery Disease
Concept Coronary Disease
Concept Cross Infection
Concept Disease Models, Animal
Concept Disease Susceptibility
Concept Glycogen Storage Disease Type II
Concept Graft vs Host Disease
Concept Heart Diseases
Concept Heart Valve Diseases
Concept Hepatic Veno-Occlusive Disease
Concept Huntington Disease
Concept Infant, Premature, Diseases
Concept Kidney Diseases
Concept Lung Diseases
Concept Lung Diseases, Obstructive
Concept Metabolic Diseases
Concept Models, Biological
Concept Models, Cardiovascular
Concept Models, Genetic
Concept Models, Theoretical
Concept Occupational Diseases
Concept Optic Nerve Diseases
Concept Orthomyxoviridae Infections
Concept Parkinson Disease
Concept Raynaud Disease
Concept Respiratory Tract Infections
Concept Ureteral Diseases
Concept Vascular Diseases
Concept Inflammatory Bowel Diseases
Concept Models, Statistical
Concept HIV Infections
Concept Linear Models
Concept Logistic Models
Concept Proportional Hazards Models
Concept Peripheral Vascular Diseases
Concept Community-Acquired Infections
Concept Disease Progression
Concept Disease-Free Survival
Concept Disease Management
Concept Genetic Predisposition to Disease
Concept Peripheral Arterial Disease
Concept Cerebral Small Vessel Diseases
Academic Article Stroke risk profile: adjustment for antihypertensive medication. The Framingham Study.
Academic Article The health risks of smoking. The Framingham Study: 34 years of follow-up.
Academic Article Age-adjusted survival curves with application in the Framingham Study.
Academic Article Development of health risk appraisal functions in the presence of multiple indicators: the Framingham Study nursing home institutionalization model.
Academic Article Left atrial size and the risk of stroke and death. The Framingham Heart Study.
Academic Article Newly diagnosed atrial fibrillation and acute stroke. The Framingham Study.
Academic Article The 'preclinical phase' of probable Alzheimer's disease. A 13-year prospective study of the Framingham cohort.
Academic Article Long-term intraindividual cholesterol variability: natural course and adverse impact on morbidity and mortality--the Framingham Study.
Academic Article Precursors of extracranial carotid atherosclerosis in the Framingham Study.
Academic Article Untreated blood pressure level is inversely related to cognitive functioning: the Framingham Study.
Academic Article The relation of hearing in the elderly to the presence of cardiovascular disease and cardiovascular risk factors.
Academic Article Aspirin use and cardiovascular disease in women.
Academic Article Incidence of dementia and probable Alzheimer's disease in a general population: the Framingham Study.
Academic Article Prevalence of dementia and probable senile dementia of the Alzheimer type in the Framingham Study.
Academic Article Robustness and power of analysis of covariance applied to data distorted from normality by floor effects: homogeneous regression slopes.
Academic Article Metabolic control and prevalent cardiovascular disease in non-insulin-dependent diabetes mellitus (NIDDM): The NIDDM Patient Outcome Research Team.
Academic Article Intermittent claudication. A risk profile from The Framingham Heart Study.
Academic Article Apolipoprotein E epsilon4 association with dementia in a population-based study: The Framingham study.
Academic Article Central auditory dysfunction, cognitive dysfunction, and dementia in older people.
Academic Article Renal arterioureteral hemorrhage: a complication of acucise endopyelotomy.
Academic Article Role of age, education, and gender on cognitive performance in the Framingham Heart Study: community-based norms.
Academic Article Lifetime risk of dementia and Alzheimer's disease. The impact of mortality on risk estimates in the Framingham Study.
Academic Article Impact of atrial fibrillation on mortality, stroke, and medical costs.
Academic Article Impact of atrial fibrillation on the risk of death: the Framingham Heart Study.
Academic Article Cost-effectiveness of statins.
Academic Article Nonfasting plasma total homocysteine levels and all-cause and cardiovascular disease mortality in elderly Framingham men and women.
Academic Article Nonfasting plasma total homocysteine levels and stroke incidence in elderly persons: the Framingham Study.
Academic Article Increased platelet aggregability associated with platelet GPIIIa PlA2 polymorphism: the Framingham Offspring Study.
Academic Article Alcohol consumption and cognitive performance in the Framingham Heart Study.
Academic Article The associations between plasma levels of von Willebrand factor and fibrinogen with Raynaud's phenomenon in men and women.
Academic Article Computing estimates of incidence, including lifetime risk: Alzheimer's disease in the Framingham Study. The Practical Incidence Estimators (PIE) macro.
Academic Article Iron status of the free-living, elderly Framingham Heart Study cohort: an iron-replete population with a high prevalence of elevated iron stores.
Academic Article Platelet glycoprotein IIIa Pl(a) polymorphism, fibrinogen, and platelet aggregability: The Framingham Heart Study.
Academic Article Validation of the Framingham coronary heart disease prediction scores: results of a multiple ethnic groups investigation.
Academic Article Association of blood pressure with fibrinolytic potential in the Framingham offspring population.
Academic Article Primary and subsequent coronary risk appraisal: new results from the Framingham study.
Academic Article Factor VII gene polymorphism, factor VII levels, and prevalent cardiovascular disease: the Framingham Heart Study.
Academic Article The preclinical phase of alzheimer disease: A 22-year prospective study of the Framingham Cohort.
Academic Article Association of fibrinogen with cardiovascular risk factors and cardiovascular disease in the Framingham Offspring Population.
Academic Article Validation of a dietary pattern approach for evaluating nutritional risk: the Framingham Nutrition Studies.
Academic Article Applicability of cholesterol-lowering primary prevention trials to a general population: the framingham heart study.
Academic Article Clinical and microbial evaluation of a histatin-containing mouthrinse in humans with experimental gingivitis.
Academic Article Total serum bilirubin and risk of cardiovascular disease in the Framingham offspring study.
Academic Article Antecedent blood pressure and risk of cardiovascular disease: the Framingham Heart Study .
Academic Article Plasma homocysteine as a risk factor for dementia and Alzheimer's disease.
Academic Article Coronary artery calcification in type 2 diabetes and insulin resistance: the framingham offspring study.
Academic Article Primary prevention drug therapy: can it meet patients' requirements for reduced risk?
Academic Article Association of C-reactive protein with carotid atherosclerosis in men and women: the Framingham Heart Study.
Academic Article [Coronary risk estimation in Spain using a calibrated Framingham function].
Academic Article Plasma homocysteine and risk for congestive heart failure in adults without prior myocardial infarction.
Academic Article Mitral annular calcification predicts cardiovascular morbidity and mortality: the Framingham Heart Study.
Academic Article Plasma total cholesterol level as a risk factor for Alzheimer disease: the Framingham Study.
Academic Article Robustness of the t test applied to data distorted from normality by floor effects.
Academic Article Alcohol consumption and risk of ischemic stroke: The Framingham Study.
Academic Article Central auditory dysfunction may precede the onset of clinical dementia in people with probable Alzheimer's disease.
Academic Article The internal validity of a dietary pattern analysis. The Framingham Nutrition Studies.
Academic Article Overweight and obesity as determinants of cardiovascular risk: the Framingham experience.
Academic Article C-reactive protein is associated with subclinical epicardial coronary calcification in men and women: the Framingham Heart Study.
Academic Article Dietary patterns and the odds of carotid atherosclerosis in women: the Framingham Nutrition Studies.
Academic Article Lower cognitive function in the presence of obesity and hypertension: the Framingham heart study.
Academic Article Robustness and power of analysis of covariance applied to ordinal scaled data as arising in randomized controlled trials.
Academic Article Temporal relations of atrial fibrillation and congestive heart failure and their joint influence on mortality: the Framingham Heart Study.
Academic Article Carotid intima-media thickness is associated with premature parental coronary heart disease: the Framingham Heart Study.
Academic Article A genome-wide search for genes affecting circulating fibrinogen levels in the Framingham Heart Study.
Academic Article An adaptation of the Framingham coronary heart disease risk function to European Mediterranean areas.
Academic Article Predictors of smoking cessation: the Framingham Study.
Academic Article Dietary patterns, smoking, and subclinical heart disease in women: opportunities for primary prevention from the Framingham Nutrition Studies.
Academic Article Absence of association between polymorphisms in the hemostatic factor pathway genes and carotid intimal medial thickness: the Framingham Heart Study.
Academic Article Mitral annular calcification is a predictor for incident atrial fibrillation.
Academic Article Overall C as a measure of discrimination in survival analysis: model specific population value and confidence interval estimation.
Academic Article Concept and usefulness of cardiovascular risk profiles.
Academic Article Mitral annular calcification and the risk of stroke in an elderly cohort.
Academic Article Cross-sectional relations of urinary sodium excretion to cardiac structure and hypertrophy. The Framingham Heart Study.
Academic Article A risk score for predicting stroke or death in individuals with new-onset atrial fibrillation in the community: the Framingham Heart Study.
Academic Article Lifetime risk of coronary heart disease by cholesterol levels at selected ages.
Academic Article Serum insulin-like growth factor I and risk for heart failure in elderly individuals without a previous myocardial infarction: the Framingham Heart Study.
Academic Article Framingham stroke risk profile and lowered cognitive performance.
Academic Article The significant effect of diabetes duration on coronary heart disease mortality: the Framingham Heart Study.
Academic Article Anger and hostility predict the development of atrial fibrillation in men in the Framingham Offspring Study.
Academic Article Accuracy of offspring reports of parental cardiovascular disease history: the Framingham Offspring Study.
Academic Article Presentation of multivariate data for clinical use: The Framingham Study risk score functions.
Academic Article Does job strain increase the risk for coronary heart disease or death in men and women? The Framingham Offspring Study.
Academic Article Parental cardiovascular disease as a risk factor for cardiovascular disease in middle-aged adults: a prospective study of parents and offspring.
Academic Article Framingham risk score and prediction of lifetime risk for coronary heart disease.
Academic Article C-reactive protein, the metabolic syndrome, and prediction of cardiovascular events in the Framingham Offspring Study.
Academic Article Alcohol consumption and the risk of bladder cancer in the Framingham Heart Study.
Academic Article Obesity and the risk of new-onset atrial fibrillation.
Academic Article Cross-sectional relations of electrocardiographic QRS duration to left ventricular dimensions: the Framingham Heart Study.
Academic Article Low-grade albuminuria and the risks of hypertension and blood pressure progression.
Academic Article Clinical research in primary stroke prevention: needs, opportunities, and challenges.
Academic Article Insulin resistance, the metabolic syndrome, and incident cardiovascular events in the Framingham Offspring Study.
Academic Article Relation of the prothrombotic state to increasing age (from the Framingham Offspring Study).
Academic Article Unique dietary patterns and chronic disease risk profiles of adult men: the Framingham nutrition studies.
Academic Article Alcohol consumption and platelet activation and aggregation among women and men: the Framingham Offspring Study.
Academic Article Cardiovascular risk factors predictive for survival and morbidity-free survival in the oldest-old Framingham Heart Study participants.
Academic Article Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus.
Academic Article Increased small low-density lipoprotein particle number: a prominent feature of the metabolic syndrome in the Framingham Heart Study.
Academic Article Sibling cardiovascular disease as a risk factor for cardiovascular disease in middle-aged adults.
Academic Article Cross-sectional association of kidney function with valvular and annular calcification: the Framingham heart study.
Academic Article Social networks and inflammatory markers in the Framingham Heart Study.
Academic Article Relations of serum uric acid to longitudinal blood pressure tracking and hypertension incidence.
Academic Article Serum cholesterol and cognitive performance in the Framingham Heart Study.
Academic Article Dietary patterns and the metabolic syndrome in obese and non-obese Framingham women.
Academic Article Relative importance of borderline and elevated levels of coronary heart disease risk factors.
Academic Article A multicenter, randomized, masked, comparison trial of lucinactant, colfosceril palmitate, and beractant for the prevention of respiratory distress syndrome among very preterm infants.
Academic Article A multicenter, randomized, controlled trial of lucinactant versus poractant alfa among very premature infants at high risk for respiratory distress syndrome.
Academic Article Compliance with expert population-based dietary guidelines and lower odds of carotid atherosclerosis in women: the Framingham Nutrition Studies.
Academic Article Influence of alcohol dehydrogenase 1C polymorphism on the alcohol-cardiovascular disease association (from the Framingham Offspring Study).
Academic Article Temporal trends in the incidence of intermittent claudication from 1950 to 1999.
Academic Article Low-grade albuminuria and incidence of cardiovascular disease events in nonhypertensive and nondiabetic individuals: the Framingham Heart Study.
Academic Article A comparison of ten-year cardiac risk estimates in schizophrenia patients from the CATIE study and matched controls.
Academic Article Tension and anxiety and the prediction of the 10-year incidence of coronary heart disease, atrial fibrillation, and total mortality: the Framingham Offspring Study.
Academic Article C-reactive protein and risk of cardiovascular disease in men and women from the Framingham Heart Study.
Academic Article Metabolic syndrome compared with type 2 diabetes mellitus as a risk factor for stroke: the Framingham Offspring Study.
Academic Article Association of educational level with inflammatory markers in the Framingham Offspring Study.
Academic Article Prediction of lifetime risk for cardiovascular disease by risk factor burden at 50 years of age.
Academic Article Variants at the APOA5 locus, association with carotid atherosclerosis, and modification by obesity: the Framingham Study.
Academic Article Electrocardiographic QRS duration and the risk of congestive heart failure: the Framingham Heart Study.
Academic Article Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular disease.
Academic Article Association of parental heart failure with risk of heart failure in offspring.
Academic Article Heritability of the ankle-brachial index: the Framingham Offspring study.
Academic Article Choice of time scale and its effect on significance of predictors in longitudinal studies.
Academic Article Gamma glutamyl transferase and metabolic syndrome, cardiovascular disease, and mortality risk: the Framingham Heart Study.
Academic Article Multiple biomarkers for the prediction of first major cardiovascular events and death.
Academic Article Stent thrombosis in randomized clinical trials of drug-eluting stents.
Academic Article Pulse pressure and risk of new-onset atrial fibrillation.
Academic Article Fucosyltransferase 3 polymorphism and atherothrombotic disease in the Framingham Offspring Study.
Academic Article Relations of inflammation and novel risk factors to valvular calcification.
Academic Article Endogenous sex hormones and cardiovascular disease incidence in men.
Academic Article Nutritional risk and the metabolic syndrome in women: opportunities for preventive intervention from the Framingham Nutrition Study.
Academic Article Variability of body weight and health outcomes in the Framingham population.
Academic Article Impact of insulin resistance on risk of type 2 diabetes and cardiovascular disease in people with metabolic syndrome.
Academic Article Increasing cardiovascular disease burden due to diabetes mellitus: the Framingham Heart Study.
Academic Article Characteristics of Framingham offspring participants with long-lived parents.
Academic Article Prevalence and prognostic impact of subclinical cardiovascular disease in individuals with the metabolic syndrome and diabetes.
Academic Article The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: design, recruitment, and initial examination.
Academic Article One-year cardiovascular event rates in outpatients with atherothrombosis.
Academic Article Relations of serum phosphorus and calcium levels to the incidence of cardiovascular disease in the community.
Academic Article Burden and prognostic importance of subclinical cardiovascular disease in overweight and obese individuals.
Academic Article Algorithms for assessing cardiovascular risk in women.
Academic Article Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study.
Academic Article Clinical utility of different lipid measures for prediction of coronary heart disease in men and women.
Academic Article Vitamin K and vitamin D status: associations with inflammatory markers in the Framingham Offspring Study.
Academic Article C-reactive protein, inflammatory conditions, and cardiovascular disease risk.
Academic Article Impact of impaired fasting glucose on cardiovascular disease: the Framingham Heart Study.
Academic Article General cardiovascular risk profile for use in primary care: the Framingham Heart Study.
Academic Article BMI vs. waist circumference for identifying vascular risk.
Academic Article Burden and rates of treatment and control of cardiovascular disease risk factors in obesity: the Framingham Heart Study.
Academic Article Prediction of incident diabetes mellitus in middle-aged adults: the Framingham Offspring Study.
Academic Article Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond.
Academic Article Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study.
Academic Article Marital status, marital strain, and risk of coronary heart disease or total mortality: the Framingham Offspring Study.
Academic Article A coronary heart disease risk model for predicting the effect of potent antiretroviral therapy in HIV-1 infected men.
Academic Article The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases.
Academic Article The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports.
Academic Article Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study.
Academic Article Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study.
Academic Article A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study.
Academic Article Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study.
Academic Article Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes.
Academic Article Vitamin D deficiency and risk of cardiovascular disease.
Academic Article Use of alternative thresholds defining insulin resistance to predict incident type 2 diabetes mellitus and cardiovascular disease.
Academic Article Aortic calcified plaques and cardiovascular disease (the Framingham Study).
Academic Article Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the Framingham heart study.
Academic Article Leukocyte telomere length and carotid artery intimal medial thickness: the Framingham Heart Study.
Academic Article Parental obesity and offspring serum alanine and aspartate aminotransferase levels: the Framingham heart study.
Academic Article Associations of adiponectin, resistin, and tumor necrosis factor-alpha with insulin resistance.
Academic Article Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality: a meta-analysis.
Academic Article Association of parental obesity with concentrations of select systemic biomarkers in nonobese offspring: the Framingham Heart Study.
Academic Article Long-term trends in the incidence of heart failure after myocardial infarction.
Academic Article Von Willebrand factor, type 2 diabetes mellitus, and risk of cardiovascular disease: the framingham offspring study.
Academic Article Development of a risk score for atrial fibrillation (Framingham Heart Study): a community-based cohort study.
Academic Article Evaluation of the Framingham risk score in the European Prospective Investigation of Cancer-Norfolk cohort--invited commentary.
Academic Article Cross-sectional relations of multiple inflammatory biomarkers to peripheral arterial disease: The Framingham Offspring Study.
Academic Article Diabetes, fibrinogen, and risk of cardiovascular disease: the Framingham experience.
Academic Article Genetics of the Framingham Heart Study population.
Academic Article Aminotransferase levels and 20-year risk of metabolic syndrome, diabetes, and cardiovascular disease.
Academic Article Genotype score in addition to common risk factors for prediction of type 2 diabetes.
Academic Article Relation of corneal arcus to cardiovascular disease (from the Framingham Heart Study data set).
Academic Article Vitamin E supplement use and the incidence of cardiovascular disease and all-cause mortality in the Framingham Heart Study: Does the underlying health status play a role?
Academic Article Advancing the hypothesis that geographic variations in risk factors contribute relatively little to observed geographic variations in heart disease and stroke mortality.
Academic Article Trends in all-cause and cardiovascular disease mortality among women and men with and without diabetes mellitus in the Framingham Heart Study, 1950 to 2005.
Academic Article Cross-sectional relations of multiple biomarkers representing distinct biological pathways to plasma markers of collagen metabolism in the community.
Academic Article Predicting the 30-year risk of cardiovascular disease: the framingham heart study.
Academic Article Trends in cardiovascular disease risk factors in individuals with and without diabetes mellitus in the Framingham Heart Study.
Academic Article Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry.
Academic Article Using survival methods to estimate age-at-onset distributions for genetic diseases with an application to Huntington disease.
Academic Article Blood pressure as a risk factor for cardiovascular disease. The Framingham Study--30 years of follow-up.
Academic Article Trajectories of entering the metabolic syndrome: the framingham heart study.
Academic Article Alterations in cholesterol absorption/synthesis markers characterize Framingham offspring study participants with CHD.
Academic Article LDL Particle Number and Risk of Future Cardiovascular Disease in the Framingham Offspring Study - Implications for LDL Management.
Academic Article Diet quality and obesity in women: the Framingham Nutrition Studies.
Academic Article Association of circulating cholesteryl ester transfer protein activity with incidence of cardiovascular disease in the community.
Academic Article C-reactive protein and reclassification of cardiovascular risk in the Framingham Heart Study.
Academic Article Abdominal subcutaneous and visceral adipose tissue and insulin resistance in the Framingham heart study.
Academic Article Gamma' fibrinogen: evaluation of a new assay for study of associations with cardiovascular disease.
Academic Article Neck circumference as a novel measure of cardiometabolic risk: the Framingham Heart study.
Academic Article Statistical methods for assessment of added usefulness of new biomarkers.
Academic Article Prior cardiovascular interventions are not associated with worsened clinical outcomes in patients with symptomatic atherothrombosis.
Academic Article Comparative determinants of 4-year cardiovascular event rates in stable outpatients at risk of or with atherothrombosis.
Academic Article Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms.
Academic Article Validation of an atrial fibrillation risk algorithm in whites and African Americans.
Academic Article Associations of carotid artery intima-media thickness (IMT) with risk factors and prevalent cardiovascular disease: comparison of mean common carotid artery IMT with maximum internal carotid artery IMT.
Academic Article Extensions of net reclassification improvement calculations to measure usefulness of new biomarkers.
Academic Article Serum gamma-glutamyl transferase and risk of heart failure in the community.
Academic Article Segment-specific association between plasma homocysteine level and carotid artery intima-media thickness in the Framingham Offspring Study.
Academic Article Relations of serum phosphorus levels to echocardiographic left ventricular mass and incidence of heart failure in the community.
Academic Article Equivalence of improvement in area under ROC curve and linear discriminant analysis coefficient under assumption of normality.
Academic Article Performance of current guidelines for coronary heart disease prevention: optimal use of the Framingham-based risk assessment.
Academic Article On the C-statistics for evaluating overall adequacy of risk prediction procedures with censored survival data.
Academic Article Frailty models: Applications to biomedical and genetic studies.
Academic Article Common carotid artery intima-media thickness progression as a predictor of stroke in multi-ethnic study of atherosclerosis.
Academic Article Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.
Academic Article Ankle-brachial index and cardiovascular risk prediction: an analysis of 11,594 individuals with 10-year follow-up.
Academic Article Objective performance goals of safety and blood pressure efficacy for clinical trials of renal artery bare metal stents in hypertensive patients with atherosclerotic renal artery stenosis.
Academic Article Assessment of genetic determinants of the association of ?' fibrinogen in relation to cardiovascular disease.
Academic Article Carotid-wall intima-media thickness and cardiovascular events.
Academic Article Sex hormone-binding globulin, but not testosterone, is associated prospectively and independently with incident metabolic syndrome in men: the framingham heart study.
Academic Article Novel metrics for evaluating improvement in discrimination: net reclassification and integrated discrimination improvement for normal variables and nested models.
Academic Article Parental intermittent claudication as risk factor for claudication in adults.
Academic Article A genetic risk score is associated with incident cardiovascular disease and coronary artery calcium: the Framingham Heart Study.
Academic Article Quantifying discrimination of Framingham risk functions with different survival C statistics.
Academic Article Defibrotide for prophylaxis of hepatic veno-occlusive disease in paediatric haemopoietic stem-cell transplantation: an open-label, phase 3, randomised controlled trial.
Academic Article Thoroughly modern risk prediction?
Academic Article A risk score for chronic kidney disease in the general population.
Academic Article Misuse of DeLong test to compare AUCs for nested models.
Academic Article Discriminating clinical features of heart failure with preserved vs. reduced ejection fraction in the community.
Academic Article An evidence-based score to detect prevalent peripheral artery disease (PAD).
Academic Article An international model to predict recurrent cardiovascular disease.
Academic Article Interpreting incremental value of markers added to risk prediction models.
Academic Article Pencina et al. respond to "The incremental value of new markers" and "Clinically relevant measures? A note of caution".
Academic Article C-reactive protein, fibrinogen, and cardiovascular disease prediction.
Academic Article Age trends in estradiol and estrone levels measured using liquid chromatography tandem mass spectrometry in community-dwelling men of the Framingham Heart Study.
Academic Article Understanding increments in model performance metrics.
Academic Article Early-adulthood cardiovascular disease risk factor profiles among individuals with and without diabetes in the Framingham Heart Study.
Academic Article Chronic kidney disease defined by cystatin C predicts mobility disability and changes in gait speed: the Framingham Offspring Study.
Academic Article Neck circumference and the development of cardiovascular disease risk factors in the Framingham Heart Study.
Academic Article Risk of type 2 diabetes and cumulative excess weight exposure in the Framingham Offspring Study.
Academic Article Relationship of lycopene intake and consumption of tomato products to incident CVD.
Academic Article Association of smoking cessation and weight change with cardiovascular disease among adults with and without diabetes.
Academic Article Sex-specific differences in the predictive value of cholesterol homeostasis markers and 10-year cardiovascular disease event rate in Framingham Offspring Study participants.
Academic Article Trends in the association of parental history of obesity over 60 years.
Academic Article Maternal factors in onset of Huntington disease.
Academic Article Fibrinogen and risk of cardiovascular disease. The Framingham Study.
Academic Article The relative importance of selected risk factors for various manifestations of cardiovascular disease among men and women from 35 to 64 years old: 30 years of follow-up in the Framingham Study.
Academic Article Functional limitations and disability among elders in the Framingham Study.
Academic Article The effect of education on the incidence of dementia and Alzheimer's disease in the Framingham Study.
Academic Article Development and testing of a new measure of case mix for use in office practice.
Academic Article Secular trends in diet and risk factors for cardiovascular disease: the Framingham Study.
Academic Article Independent risk factors for atrial fibrillation in a population-based cohort. The Framingham Heart Study.
Academic Article Physical activity and risk of breast cancer in the Framingham Heart Study.
Academic Article Dietary lipid predictors of coronary heart disease in men. The Framingham Study.
Academic Article Hypertension, antihypertensive treatment, and sudden coronary death. The Framingham Study.
Academic Article Diet, menopause, and serum cholesterol levels in women: the Framingham Study.
Academic Article Chemokine receptor mutant CX3CR1-M280 has impaired adhesive function and correlates with protection from cardiovascular disease in humans.
Academic Article Sex and age differences in lipoprotein subclasses measured by nuclear magnetic resonance spectroscopy: the Framingham Study.
Academic Article Cardiovascular Disease Risk Assessment: Insights from Framingham.
Academic Article Stenting and medical therapy for atherosclerotic renal-artery stenosis.
Academic Article Application of new cholesterol guidelines to a population-based sample.
Academic Article Evaluating Discrimination of Risk Prediction Models: The C Statistic.
Academic Article Biomarkers of oxidative stress are associated with frailty: the Framingham Offspring Study.
Academic Article The Contribution of Autonomic Imbalance to the Development of Metabolic Syndrome.
Academic Article Quantifying cardiometabolic risk using modifiable non-self-reported risk factors.
Academic Article Hyperlipidemia in early adulthood increases long-term risk of coronary heart disease.
Academic Article Apolipoprotein B improves risk assessment of future coronary heart disease in the Framingham Heart Study beyond LDL-C and non-HDL-C.
Academic Article Biomarkers of cardiovascular stress and subclinical atherosclerosis in the community.
Academic Article What to expect from net reclassification improvement with three categories.
Academic Article Medical history for prognostic risk assessment and diagnosis of stable patients with suspected coronary artery disease.
Academic Article Guideline-Based Statin Eligibility, Coronary Artery Calcification, and Cardiovascular Events.
Academic Article Inference of bioequivalence for log-normal distributed data with unspecified variances.
Academic Article Impact of farnesylation inhibitors on survival in Hutchinson-Gilford progeria syndrome.
Academic Article Long-term risk of cardiovascular events across a spectrum of adverse major plasma lipid combinations in the Framingham Heart Study.
Academic Article Calibration and Discrimination Among Multiple Cardiovascular Risk Scores in a Modern Multiethnic Cohort.
Academic Article The Role of Physicians in the Era of Predictive Analytics.
Academic Article Five-Year Risk of Mechanical Ventilation in Community-Dwelling Adults: The Framingham-Intermountain Anticipating Life Support Study.
Academic Article Response to Letter Regarding Article, "Hyperlipidemia in Early Adulthood Increases Long-Term Risk of Coronary Heart Disease".
Academic Article Impact of correlation on predictive ability of biomarkers.
Academic Article Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events.
Academic Article Sensitivity and specificity can change in opposite directions when new predictive markers are added to risk models.
Academic Article Assessing the incremental predictive performance of novel biomarkers over standard predictors.
Academic Article Net reclassification improvement and integrated discrimination improvement require calibrated models: relevance from a marker and model perspective.
Academic Article Graphical assessment of incremental value of novel markers in prediction models: From statistical to decision analytical perspectives.
Academic Article Using age- and sex-specific risk thresholds to guide statin therapy: one size may not fit all.
Academic Article A systems analysis of age-related changes in some cardiac aging traits.
Academic Article Inference of equivalence for the ratio of two normal means with unspecified variances.
Academic Article Covariate effect on constancy assumption in noninferiority clinical trials.
Academic Article Autonomic Imbalance as a Predictor of Metabolic Risks, Cardiovascular Disease, Diabetes, and Mortality.
Academic Article Incident Type 2 Myocardial Infarction in a Cohort of Patients Undergoing Coronary or Peripheral Arterial Angiography.
Academic Article Carotid Atherosclerosis and Cerebral Microbleeds: The Framingham Heart Study.
Academic Article Temporal Changes in the Association Between Modifiable Risk Factors and Coronary Heart Disease Incidence.
Academic Article Residential Proximity to Major Roads, Exposure to Fine Particulate Matter, and Coronary Artery Calcium: The Framingham Heart Study.
Academic Article Circulating Proneurotensin Concentrations and Cardiovascular Disease Events in the Community: The Framingham Heart Study.
Academic Article Plasminogen activator inhibitor and the risk of cardiovascular disease: The Framingham Heart Study.
Academic Article Cardiovascular Event Prediction and Risk Reclassification by Coronary, Aortic, and Valvular Calcification in the Framingham Heart Study.
Academic Article Discrimination slope and integrated discrimination improvement - properties, relationships and impact of calibration.
Academic Article Revised Framingham Stroke Risk Profile to Reflect Temporal Trends.
Academic Article Effects of Stenting for Atherosclerotic Renal Artery Stenosis on eGFR and Predictors of Clinical Events in the CORAL Trial.
Academic Article Lung Cancer Screening Eligibility in the Community: Cardiovascular Risk Factors, Coronary Artery Calcification, and Cardiovascular Events.
Academic Article Phase 3 trial of defibrotide for the treatment of severe veno-occlusive disease and multi-organ failure.
Academic Article Remnant Lipoprotein Cholesterol and Incident Coronary Heart Disease: The Jackson Heart and Framingham Offspring Cohort Studies.
Academic Article Net reclassification index at event rate: properties and relationships.
Academic Article Greater remnant lipoprotein cholesterol reduction with pitavastatin compared with pravastatin in HIV-infected patients.
Academic Article Mortality Following Cardiovascular and Bleeding Events Occurring Beyond 1 Year After Coronary Stenting: A Secondary Analysis of the Dual Antiplatelet Therapy (DAPT) Study.
Academic Article Relation of Risk Factors and Abdominal Aortic Calcium to Progression of Coronary Artery Calcium (from the Framingham Heart Study).
Academic Article Asymptotic distribution of ?AUC, NRIs, and IDI based on theory of U-statistics.
Academic Article Guideline-Based Statin Eligibility, Cancer Events, and Noncardiovascular Mortality in the Framingham Heart Study.
Academic Article Association of Coronary Artery Calcium Score vs Age With Cardiovascular Risk in Older Adults: An Analysis of Pooled Population-Based Studies.
Academic Article Coronary Artery Calcium Distribution Is an Independent Predictor of Incident Major Coronary Heart Disease Events: Results From the Framingham Heart Study.
Academic Article Association of Multiorgan Computed Tomographic Phenomap With Adverse Cardiovascular Health Outcomes: The Framingham Heart Study.
Academic Article Increased Aortic Diameters on Multidetector Computed Tomographic Scan Are Independent Predictors of Incident Adverse Cardiovascular Events: The Framingham Heart Study.
Academic Article Predicting new-onset HF in patients undergoing coronary or peripheral angiography: results from the Catheter Sampled Blood Archive in Cardiovascular Diseases (CASABLANCA) study.
Academic Article Cardiovascular Risk Prediction Functions Underestimate Risk in HIV Infection.
Academic Article Single-Molecule Counting of High-Sensitivity Troponin I in Patients Referred for Diagnostic Angiography: Results From the CASABLANCA (Catheter Sampled Blood Archive in Cardiovascular Diseases) Study.
Academic Article High-density lipoproteins: a consensus statement from the National Lipid Association.
Academic Article Temporal Associations Between Smoking and Cardiovascular Disease, 1971 to 2006 (from the Framingham Heart Study).
Academic Article Cigarette smoking and cardio-renal events in patients with atherosclerotic renal artery stenosis.
Academic Article Tutorial on statistical considerations on subgroup analysis in confirmatory clinical trials.
Academic Article Developing points-based risk-scoring systems in the presence of competing risks.
Academic Article Inclusion of Flagellin during Vaccination against Influenza Enhances Recall Responses in Nonhuman Primate Neonates.
Academic Article Genome wide identification of new genes and pathways in patients with both autoimmune thyroiditis and type 1 diabetes.
Academic Article Effects of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies in Adults With Hypercholesterolemia: A Systematic Review and Meta-analysis.
Academic Article Glycated hemoglobin measurement and prediction of cardiovascular disease.
Academic Article Risk estimation for recurrent Clostridium difficile infection based on clinical factors.
Academic Article 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.
Academic Article Extension of adaptive alpha allocation methods for strong control of the family-wise error rate.
Academic Article Lipid-related markers and cardiovascular disease prediction.
Academic Article Cardiovascular risk estimation in 2012: lessons learned and applicability to the HIV population.
Academic Article Patterns of weight change and progression to overweight and obesity differ in men and women: implications for research and interventions.
Academic Article Adverse outcome analyses of observational data: assessing cardiovascular risk in HIV disease.
Academic Article Stability of the Framingham Nutritional Risk Score and its component nutrients over 8 years: the Framingham Nutrition Studies.
Academic Article Prevalence and characteristics of the metabolic syndrome in the San Antonio Heart and Framingham Offspring Studies.
Academic Article Pioglitazone versus glimepiride on coronary artery calcium progression in patients with type 2 diabetes mellitus: a secondary end point of the CHICAGO study.
Academic Article Relationship of traditional and nontraditional cardiovascular risk factors to coronary artery calcium in type 2 diabetes.
Academic Article Cardiovascular risk-estimation systems in primary prevention: do they differ? Do they make a difference? Can we see the future?
Academic Article Beyond baseline data: the use of time-varying covariates.
Academic Article Trends in cardiovascular complications of diabetes.
Academic Article Increased high-density lipoprotein cholesterol predicts the pioglitazone-mediated reduction of carotid intima-media thickness progression in patients with type 2 diabetes mellitus.
Academic Article Search for an optimal atherogenic lipid risk profile: from the Framingham Study.
Academic Article Making genuine progress against metastatic breast cancer.
Academic Article The delayed-start study design.
Academic Article Prediction of coronary heart disease risk in HIV-infected patients with fat redistribution.
Academic Article Changing end points in breast-cancer drug approval--the Avastin story.
Academic Article Validity of an adaptation of the Framingham cardiovascular risk function: the VERIFICA Study.
Academic Article External validity of predictive models: a comparison of logistic regression, classification trees, and neural networks.
Academic Article Relationship of abdominal visceral and subcutaneous adipose tissue with lipoprotein particle number and size in type 2 diabetes.
Academic Article Predictors of mortality for lower respiratory infections in nursing home residents with dementia were validated transnationally.
Academic Article Time-dependent predictors of primary cardiac arrest in patients with acute myocardial infarction.
Academic Article Predictors of short-term functional decline in survivors of nursing home-acquired lower respiratory tract infection.
Academic Article Autonomic Imbalance as a Predictor of Metabolic Risks, Cardiovascular Disease, Diabetes, and Mortality Autonomic Imbalance Predicts CVD, DM, Mortality.
Academic Article Circulating folic acid in plasma: relation to folic acid fortification.
Academic Article Stent revascularization for the prevention of cardiovascular and renal events among patients with renal artery stenosis and systolic hypertension: rationale and design of the CORAL trial.
Academic Article Fasting and postchallenge glycemia and cardiovascular disease risk: the Framingham Offspring Study.
Academic Article Efficacy endpoint selection and multiplicity adjustment methods in clinical trials with inherent multiple endpoint issues.
Academic Article Effect of pioglitazone compared with glimepiride on carotid intima-media thickness in type 2 diabetes: a randomized trial.
Academic Article Longitudinal association of glycemia and microalbuminuria: the Framingham Offspring Study.
Academic Article Development of appropriate coronary heart disease risk prediction models in HIV-infected patients.
Academic Article Impact of enzyme replacement therapy on survival in adults with Pompe disease: results from a prospective international observational study.
Academic Article Does hospitalization impact survival after lower respiratory infection in nursing home residents?
Academic Article Attained educational level and incident atherothrombotic events in low- and middle-income compared with high-income countries.
Academic Article A likely explanation for the J-curve of blood pressure cardiovascular risk.
Academic Article Prevalence, clinical profile, and cardiovascular outcomes of atrial fibrillation patients with atherothrombosis.
Academic Article Global risk assessment for cardiovascular disease and astute clinical judgement.
Academic Article Age and time need not and should not be eliminated from the coronary risk prediction models.
Academic Article Predictive value for the Chinese population of the Framingham CHD risk assessment tool compared with the Chinese Multi-Provincial Cohort Study.
Academic Article Monocyte cytokine production, systemic inflammation and cardiovascular disease in very elderly men and women: the Framingham Heart Study.
Academic Article Antibiotic treatment and survival of nursing home patients with lower respiratory tract infection: a cross-national analysis.
Academic Article Association between increased homocysteine levels and impaired fibrinolytic potential: potential mechanism for cardiovascular risk.
Academic Article Validated prediction model for the development of primary open-angle glaucoma in individuals with ocular hypertension.
Academic Article Estimating treatment effects using observational data.
Academic Article Sudden coronary death in women.
Academic Article Maximum likelihood estimation for interval-censored data using a Weibull-based accelerated failure time model.
Academic Article A technique for summarizing longitudinal data.
Academic Article Sex and time trends in cardiovascular disease incidence and mortality: the Framingham Heart Study, 1950-1989.
Academic Article A comparison of performance of mathematical predictive methods for medical diagnosis: identifying acute cardiac ischemia among emergency department patients.
Academic Article Is coronary-care-unit admission restricted for elderly patients? A multicenter study.
Academic Article Clustering of metabolic factors and coronary heart disease.
Academic Article Determinants of isolated systolic hypertension.
Academic Article Fibrinogen, cigarette smoking, and risk of cardiovascular disease: insights from the Framingham Study.
Academic Article Comparison of past versus recent physical activity in the prevention of premature death and coronary artery disease.
Academic Article High intraocular pressure and survival: the Framingham Studies.
Academic Article Patient-specific predictions of outcomes in myocardial infarction for real-time emergency use: a thrombolytic predictive instrument.
Academic Article Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study. Sleep Heart Health Study.
Academic Article G-estimation of causal effects: isolated systolic hypertension and cardiovascular death in the Framingham Heart Study.
Academic Article Predictive value of T-wave alternans for arrhythmic events in patients with congestive heart failure.
Academic Article Influence of heart rate on mortality among persons with hypertension: the Framingham Study.
Academic Article Metabolic abnormalities and cardiovascular disease risk factors in adults with human immunodeficiency virus infection and lipodystrophy.
Academic Article Profile for estimating risk of heart failure.
Academic Article Decisive factors in the tolbutamide controversy.
Academic Article Systematically missing confounders in individual participant data meta-analysis of observational cohort studies.
Academic Article Physician electrocardiogram reading in the emergency department--accuracy and effect on triage decisions: findings from a multicenter study.
Academic Article Update on fibrinogen as a cardiovascular risk factor.
Academic Article Dietary predictors of serum cholesterol in men: the Framingham cohort population.
Academic Article Efficacy and tolerability of lovastatin in hypercholesterolemia in patients with systemic hypertension.
Academic Article A time-insensitive predictive instrument for acute myocardial infarction mortality: a multicenter study.
Academic Article Comparison of techniques for estimating nutrient intake: the Framingham Study.
Academic Article Efficacy and tolerability of lovastatin in elderly hypercholesterolemic patients.
Academic Article Prediction of coronary heart disease using risk factor categories.
Academic Article Testing a model that evaluates options for rural Emergency Medical Service development.
Academic Article Technology assessment in the Framingham Heart Study.
Academic Article Risk for cardiovascular disease in the elderly and associated Medicare costs: the Framingham Study.
Academic Article Increased PAI-1 and tPA antigen levels are reduced with metformin therapy in HIV-infected patients with fat redistribution and insulin resistance.
Academic Article Benefits and adverse effects of weight loss. Observations from the Framingham Study.
Academic Article Does number of children increase the rate of coronary heart disease in men?
Academic Article Benefits and pitfalls of pooling datasets from comparable observational studies: combining US and Dutch nursing home studies.
Academic Article Cardiovascular risk assessment based on US cohort studies: findings from a National Heart, Lung, and Blood institute workshop.
Academic Article Fasting plasma homocysteine levels in the insulin resistance syndrome: the Framingham offspring study.
Academic Article Prevention Conference V: Beyond secondary prevention: identifying the high-risk patient for primary prevention: medical office assessment: Writing Group I.
Academic Article Clinical findings associated with radiographic pneumonia in nursing home residents.
Academic Article Predicting mortality in nursing home residents with lower respiratory tract infection: The Missouri LRI Study.
Academic Article Comparison of baseline and repeated measure covariate techniques in the Framingham Heart Study.
Academic Article A tool for judging coronary care unit admission appropriateness, valid for both real-time and retrospective use. A time-insensitive predictive instrument (TIPI) for acute cardiac ischemia: a multicenter study.
Academic Article Physical activity and physical demand on the job and risk of cardiovascular disease and death: the Framingham Study.
Academic Article Long-term influence of fibrinogen on initial and recurrent cardiovascular events in men and women.
Academic Article Issues of study design and data analysis.
Academic Article Association of epidural analgesia with cesarean delivery in nulliparas.
Academic Article Combining single patient (N-of-1) trials to estimate population treatment effects and to evaluate individual patient responses to treatment.
Academic Article A predictive instrument to improve coronary-care-unit admission practices in acute ischemic heart disease. A prospective multicenter clinical trial.
Academic Article An aid for diagnosing acute ischemic heart disease in the emergency room.
Academic Article A logistic regression model when some events precede treatment: the effect of thrombolytic therapy for acute myocardial infarction on the risk of cardiac arrest.
Academic Article Do patients'' coronary risk factor reports predict acute cardiac ischemia in the emergency department? A multicenter study.
Academic Article The usefulness of a predictive instrument to reduce inappropriate admissions to the coronary care unit.
Academic Article Efficacy and tolerability of lovastatin in hypercholesterolemic women.
Academic Article Relation of low diastolic blood pressure to coronary heart disease death in presence of myocardial infarction: the Framingham Study.
Academic Article Electrocardiographic left ventricular hypertrophy in patients with suspected acute cardiac ischemia--its influence on diagnosis, triage, and short-term prognosis: a multicenter study.
Academic Article Role of smoking in the U-shaped relation of cholesterol to mortality in men. The Framingham Study.
Academic Article Measuring effectiveness. What to expect without a randomized control group.
Academic Article The exclusion of women from clinical trials of thrombolytic therapy: implications for developing the thrombolytic predictive instrument database.
Academic Article Physical activity and mortality in women in the Framingham Heart Study.
Academic Article Does exercise reduce mortality rates in the elderly? Experience from the Framingham Heart Study.
Academic Article Therapeutic benefit. Aspirin revisited in light of the introduction of clopidogrel.
Academic Article Hyperinsulinemia, hyperglycemia, and impaired hemostasis: the Framingham Offspring Study.
Academic Article 27th Bethesda Conference: matching the intensity of risk factor management with the hazard for coronary disease events. Task Force 5. Stratification of patients into high, medium and low risk subgroups for purposes of risk factor management.
Academic Article Missed diagnoses of acute myocardial infarction in the emergency department: results from a multicenter study.
Academic Article A comparison of logistic regression to decision-tree induction in a medical domain.
Academic Article Primary prevention of cardiovascular disease: a web-based risk score for seven British black and minority ethnic groups.
Academic Article A predictive instrument for acute ischemic heart disease to improve coronary care unit admission practices: a potential on-line tool in a computerized electrocardiograph.
Academic Article Effect of weight on cardiovascular disease.
Academic Article Secular trends in long-term sustained hypertension, long-term treatment, and cardiovascular mortality. The Framingham Heart Study 1950 to 1990.
Academic Article Use of vital capacity for cardiac failure risk estimation in persons with coronary disease and left ventricular hypertrophy.
Academic Article Differential effects of experience on house officers'' admission diagnoses for patients with possible myocardial infarction.
Academic Article Age-specific incidence rates of myocardial infarction and angina in women with systemic lupus erythematosus: comparison with the Framingham Study.
Academic Article The logistic function as an aid in the detection of acute coronary disease in emergency patients (a case study).
Academic Article Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis.
Academic Article How do physicians adapt when the coronary care unit is full? A prospective multicenter study.
Academic Article Sudden death risk in overt coronary heart disease: the Framingham Study.
Academic Article An analytic method for the evaluation of rural Emergency Medical Service development.
Academic Article Baldness and coronary heart disease rates in men from the Framingham Study.
Academic Article The appropriateness of analysis of variance to the statistical analyses of dental clinical trials.
Academic Article Presenting pulse pressure predicts thrombolytic therapy-related intracranial hemorrhage. Thrombolytic Predictive Instrument (TPI) Project results.
Academic Article Prognostic implications of baseline electrocardiographic features and their serial changes in subjects with left ventricular hypertrophy.
Academic Article A time-insensitive predictive instrument for acute hospital mortality due to congestive heart failure: development, testing, and use for comparing hospitals: a multicenter study.
Academic Article Relation of pooled logistic regression to time dependent Cox regression analysis: the Framingham Heart Study.
Academic Article Changes in risk factors and the decline in mortality from cardiovascular disease. The Framingham Heart Study.
Academic Article Blood pressure and cardiovascular morbidity and mortality rates in the elderly.
Academic Article Application of net reclassification index to non-nested and point-based risk prediction models: a review.
Academic Article International Validation of the Thrombolysis in Myocardial Infarction (TIMI) Risk Score for Secondary Prevention in Post-MI Patients: A Collaborative Analysis of the Chronic Kidney Disease Prognosis Consortium and the Risk Validation Scientific Committee.
Academic Article Harmony Outcomes: A randomized, double-blind, placebo-controlled trial of the effect of albiglutide on major cardiovascular events in patients with type 2 diabetes mellitus-Rationale, design, and baseline characteristics.
Academic Article Microsimulation model to predict incremental value of biomarkers added to prognostic models.
Academic Article Endothelin-1 Measurement in Patients Undergoing Diagnostic Coronary Angiography-Results from the Catheter Sampled Blood Archive in Cardiovascular Diseases (CASABLANCA) Study.
Academic Article Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial.
Academic Article Estimated Life Expectancy Without Recurrent Cardiovascular Events in Patients With Vascular Disease: The SMART-REACH Model.
Academic Article Quantifying Importance of Major Risk Factors for Coronary Heart Disease.
Academic Article Blood kidney injury molecule-1 predicts short and longer term kidney outcomes in patients undergoing diagnostic coronary and/or peripheral angiography-Results from the Catheter Sampled Blood Archive in Cardiovascular Diseases (CASABLANCA) study.
Academic Article Measures for evaluation of prognostic improvement under multivariate normality for nested and nonnested models.

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