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Search Results to David T. Felson, MD, MPH

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Research Expertise & Professional Interests Dr. David Felson's research interests include: understanding how to prevent osteoarthritis and treat osteoarthritis. In osteoarthritis, Dr. Felson’s interests include studying whether treatments for rheumatic diseases are effective and particularly in osteoarthritis, identifying biomechanical risk factors for disease and testing biomechanical treatments and characterizing MRI features of normal knees and knees with pain. He also studies outcome measurement in rheumatic disease and has focused in this work on rheumatoid arthritis trials.

One or more keywords matched the following items that are connected to Felson, David

Item TypeName
Concept Clinical Trials as Topic
Concept Research
Concept Research Design
Concept Research Support as Topic
Concept Peer Review, Research
Concept Controlled Clinical Trials as Topic
Concept Clinical Chemistry Tests
Concept Biomedical Research
Concept Qualitative Research
Academic Article American College of Rheumatology. Preliminary definition of improvement in rheumatoid arthritis.
Academic Article Clinical measures in rheumatoid arthritis: which are most useful in assessing patients?
Academic Article World Health Organization and International League of Associations for Rheumatology core endpoints for symptom modifying antirheumatic drugs in rheumatoid arthritis clinical trials.
Academic Article A study of manufacturer-supported trials of nonsteroidal anti-inflammatory drugs in the treatment of arthritis.
Academic Article Problems and suggested solutions in creating an archive of clinical trials data to permit later meta-analysis: an example of methotrexate trials in rheumatoid arthritis.
Academic Article Musculoskeletal disease research: should we analyze the joint or the person?
Academic Article Osteoporosis clinical trials endpoints: candidate variables and clinimetric properties.
Academic Article Critique of meta-analysis of second-line antirheumatic drugs.
Academic Article Choosing a core set of disease activity measures for rheumatoid arthritis clinical trials.
Academic Article The American College of Rheumatology preliminary core set of disease activity measures for rheumatoid arthritis clinical trials. The Committee on Outcome Measures in Rheumatoid Arthritis Clinical Trials.
Academic Article Clinical trials in rheumatoid arthritis under attack: are practice based observational studies the answer?
Academic Article Defining clinical improvement in rheumatoid arthritis.
Academic Article Should improvement in rheumatoid arthritis clinical trials be defined as fifty percent or seventy percent improvement in core set measures, rather than twenty percent?
Academic Article Estrogen and osteoarthritis: how do we explain conflicting study results?
Academic Article Early stopping of clinical trials in lupus and other uncommon rheumatologic diseases.
Academic Article Glucosamine and chondroitin for treatment of osteoarthritis: a systematic quality assessment and meta-analysis.
Academic Article The verdict favors nonsteroidal antiinflammatory drugs for treatment of osteoarthritis and a plea for more evidence on other treatments.
Academic Article A review of evidence on the discriminant validity of outcome measures in rheumatoid arthritis.
Academic Article Minimal clinically important difference module: summary, recommendations, and research agenda.
Academic Article Problems in the development and validation of questionnaire-based screening instruments for ascertaining cases with symptomatic knee osteoarthritis: the Framingham Study.
Academic Article Statistical presentation and analysis of ordered categorical outcome data in rheumatology journals.
Academic Article Discrepancy between published report and actual conduct of randomized clinical trials.
Academic Article Blocking tumor necrosis factor inhibits radiographic damage even in patients who show minimal or no clinical improvement: comment on the concise communication by Boers.
Academic Article Use of short-term efficacy/toxicity tradeoffs to select second-line drugs in rheumatoid arthritis. A metaanalysis of published clinical trials.
Academic Article The clinical importance of meniscal tears demonstrated by magnetic resonance imaging in osteoarthritis of the knee.
Academic Article An index of the three core data set patient questionnaire measures distinguishes efficacy of active treatment from that of placebo as effectively as the American College of Rheumatology 20% response criteria (ACR20) or the Disease Activity Score (DAS) in a rheumatoid arthritis clinical trial.
Academic Article MCID/Low Disease Activity State Workshop: summary, recommendations, and research agenda.
Academic Article Secular changes in the quality of published randomized clinical trials in rheumatology.
Academic Article Truth survival.
Academic Article Hierarchy of evidence: from case reports to randomized controlled trials.
Academic Article Comparison of rheumatoid arthritis clinical trial outcome measures: a simulation study.
Academic Article Evaluation of clinically relevant changes in patient reported outcomes in knee and hip osteoarthritis: the minimal clinically important improvement.
Academic Article Bias in meta-analytic research.
Academic Article Epidemiologic studies for osteoarthritis: new versus conventional study design approaches.
Academic Article Assessing the efficacy and safety of rheumatic disease treatments: obstacles and proposed solutions.
Academic Article Intra-articular hyaluronic acid in treatment of knee osteoarthritis: a meta-analysis.
Academic Article Evaluation of clinically relevant states in patient reported outcomes in knee and hip osteoarthritis: the patient acceptable symptom state.
Academic Article A surplus of positive trials: weighing biases and reconsidering equipoise.
Academic Article What WOMAC pain score should make a patient eligible for a trial in knee osteoarthritis?
Academic Article Secular changes in published clinical trials of second-line agents in rheumatoid arthritis.
Academic Article Minimal disease activity for rheumatoid arthritis: a preliminary definition.
Academic Article Current status of outcome measures in vasculitis: focus on Wegener's granulomatosis and microscopic polyangiitis. Report from OMERACT 7.
Academic Article Clinical practice. Osteoarthritis of the knee.
Academic Article Examining a whole-organ magnetic resonance imaging scoring system for osteoarthritis of the knee using Rasch analysis.
Academic Article The online case-crossover study is a novel approach to study triggers for recurrent disease flares.
Academic Article Contributions of OMERACT to rheumatic disease research.
Academic Article Glucosamine for pain in osteoarthritis: why do trial results differ?
Academic Article Composite versus individual measures of disease activity in rheumatoid arthritis.
Academic Article Rationale and strategies for reevaluating the ACR20.
Academic Article Minimal clinically important improvement and patient acceptable symptom state for subjective outcome measures in rheumatic disorders.
Academic Article Classification criteria in rheumatic diseases: a review of methodologic properties.
Academic Article Trials in rheumatoid arthritis: choosing the right outcome measure when minimal disease is achievable.
Academic Article Vitamin K in hand osteoarthritis: results from a randomised clinical trial.
Academic Article Developments in the clinical understanding of osteoarthritis.
Academic Article Reporting disease activity in clinical trials of patients with rheumatoid arthritis: EULAR/ACR collaborative recommendations.
Academic Article Methods of deriving EULAR/ACR recommendations on reporting disease activity in clinical trials of patients with rheumatoid arthritis.
Academic Article Reporting disease activity in clinical trials of patients with rheumatoid arthritis: EULAR/ACR collaborative recommendations.
Academic Article A computer-adaptive disability instrument for lower extremity osteoarthritis research demonstrated promising breadth, precision, and reliability.
Academic Article Which traditional measures should be used in rheumatoid arthritis clinical trials?
Academic Article Epidemiologic research in fibromyalgia.
Academic Article Clinically important improvement in function is common in people with or at high risk of knee OA: the MOST study.
Academic Article The 2010 American College of Rheumatology/European League Against Rheumatism classification criteria for rheumatoid arthritis: Phase 2 methodological report.
Academic Article Creating a K-community of investigators.
Academic Article American College of Rheumatology/European League against Rheumatism provisional definition of remission in rheumatoid arthritis for clinical trials.
Academic Article American College of Rheumatology/European League Against Rheumatism provisional definition of remission in rheumatoid arthritis for clinical trials.
Academic Article Osteoarthritis: Virtual joint replacement as an outcome measure in OA.
Academic Article Minimum clinically important improvement and patient acceptable symptom state in pain and function in rheumatoid arthritis, ankylosing spondylitis, chronic back pain, hand osteoarthritis, and hip and knee osteoarthritis: Results from a prospective multinational study.
Academic Article Validation of ACR/EULAR definition of remission in rheumatoid arthritis from RA practice: the ESPOIR cohort.
Academic Article Motion for debate: osteoarthritis clinical trials have not identified efficacious therapies because traditional imaging outcome measures are inadequate.
Academic Article Time for changes in the design, analysis, and reporting of rheumatoid arthritis clinical trials.
Academic Article A randomized, controlled trial of amitriptyline and naproxen in the treatment of patients with fibromyalgia.
Academic Article Evidence for the superiority of immunosuppressive drugs and prednisone over prednisone alone in lupus nephritis. Results of a pooled analysis.
Academic Article Fibromyalgia syndrome in patients infected with human immunodeficiency virus. The Boston City Hospital Clinical AIDS Team.
Academic Article The efficacy and toxicity of combination therapy in rheumatoid arthritis. A meta-analysis.
Academic Article Osteoarthritis: priorities for osteoarthritis research: much to be done.
Academic Article Magnetic resonance imaging of Hoffa''s fat pad and relevance for osteoarthritis research: a narrative review.
Academic Article Does clinically important change in function after knee replacement guarantee good absolute function? The multicenter osteoarthritis study.
Academic Article "Fear of the Known and Unknown": Factors Affecting Participation Following Knee Replacement Among Persons With Participation Restriction.
Academic Article Clinical assessment of effusion in knee osteoarthritis-A systematic review.
Academic Article The Minimum Clinically Important Improvement and Patient-acceptable Symptom State in the BASDAI and BASFI for Patients with Ankylosing Spondylitis.
Academic Article Obesity Paradox in Recurrent Attacks of Gout in Observational Studies: Clarification and Remedy.
Academic Article Why methotrexate suboptimal dosing is a potential source of bias in biologic drugs clinical trials.
Academic Article Recommendations for the conduct of efficacy trials of treatment devices for osteoarthritis: a report from a working group of the Arthritis Research UK Osteoarthritis and Crystal Diseases Clinical Studies Group.
Academic Article Harmonising data collection from osteoarthritis studies to enable stratification: recommendations on core data collection from an Arthritis Research UK clinical studies group.
Academic Article Methotrexate dosage as a source of bias in biological trials in rheumatoid arthritis: a systematic review.
Academic Article Interobserver and Intraobserver Reliability of Clinical Assessments in Knee Osteoarthritis.
Award or Honor Receipt Dr. Marian Ropes Award for research accomplishments, patient care and teaching
Academic Article Development and validation of a patient-reported outcome instrument for skin involvement in patients with systemic sclerosis.
Academic Article Use of Diagnostic Performance of Clinical Examination Measures and Pain Presentation to Identify Patellofemoral Joint Osteoarthritis.
Grant Boston University Clinical Research Training (CREST) Program
Award or Honor Receipt Lifetime Achievement Award
Award or Honor Receipt Clinical Research Award
Academic Article Emerging Treatment Models in Rheumatology: Challenges for Osteoarthritis Trials.
Academic Article The role of radiography and MRI for eligibility assessment in DMOAD trials of knee OA.
Academic Article Clinical Problems in Acute Care Medicine (Heffernan JJ, Witzburg RA, Cohen AS, eds.)
Academic Article Clinical Problems in Acute Care Medicine (Heffernan JJ, Witzburg RA, Cohen AS, eds.)
Academic Article Clinical Problems in Acute Care Medicine (Heffernan JJ, Witzburg RA, Cohen AS, eds.)
Academic Article Clinical Problems in Acute Care Medicine (Heffernan JJ, Witzburg RA, Cohen AS, eds.)
Academic Article Osteoarthritis (Brandt K, Lohmander S, Doherty M eds.)
Academic Article Encyclopedia of Biostatistics (Armitage P, Colton T, eds.)
Academic Article Obesity: Mechanisms and Clinical Management (Eckel RH ed.)
Academic Article 75th Anniversary of the American College of Rheumatology (Pisetsky, ed.)
Academic Article Recovery after unilateral knee replacement due to severe osteoarthritis and progression in the contralateral knee: a randomised clinical trial comparing daily 2000 IU versus 800 IU vitamin D.
Academic Article Changes in Pain Sensitization after Bariatric Surgery
Academic Article Foot and ankle biomechanics play a role in biomechanical response to lateral wedge insoles
Academic Article 172 THE RELATIONSHIP BETWEEN TOE-OUT DURING WALKING AND CLINICAL CHARACTERISTICS OF 1ST METATARSOPHALANGEAL JOINT OSTEOARTHRITIS: THE MOST STUDY
Academic Article Evaluation of clinically relevant changes and states in symptomatic outcome variables in osteoarthritis
Academic Article Knee osteoarthritis: does physiotherapy help?
Academic Article Encyclopedia of Biostatistics
Academic Article Natural history of kyphosis: A prospective study of change in thoracic curvature in men and women in the Framingham Study
Academic Article Journal of Bone and Mineral Research
Academic Article Patient questionnaire data discriminate between drug versus placebo as effectively as the ACR20 in a clinical trial of patients with rheumatoid arthritis (RA)
Academic Article Serum estradiol and the risk for hip fractures in elderly men: The Framingham Study
Academic Article Is the effect of smoking on bone mineral density (BMD) in elderly men mediated through estradiol (E2)? The Framingham osteoporosis study
Academic Article Risk factors for incidence of vertebral fracture in men and women: 25-year fellow-up results from the Framingham osteoporosis study
Academic Article Improvement in quality but persistent methodological deficiencies in randomized clinical trials (RCT) reports in rheumatology: 1987/8 vs. 1997/8
Academic Article Reduced joint counts in rheumatoid arthritis clinical trials. American College of Rheumatology Committee on Outcome Measures in Rheumatoid Arthritis Clinical Trials.
Academic Article The effect of age and renal function on the efficacy and toxicity of methotrexate in rheumatoid arthritis. Rheumatoid Arthritis Clinical Trial Archive Group.
Academic Article Towards prevention of post-traumatic osteoarthritis: report from an international expert working group on considerations for the design and conduct of interventional studies following acute knee injury.
Academic Article The Efficacy of a Lateral Wedge Insole for Painful Medial Knee Osteoarthritis After Prescreening: A Randomized Clinical Trial.
Academic Article Do Clinical Correlates of Knee Osteoarthritis Predict Outcome of Intraarticular Steroid Injections?
Academic Article MRI-based screening for structural definition of eligibility in clinical DMOAD trials: Rapid OsteoArthritis MRI Eligibility Score (ROAMES).
Grant The Boston University Clinical and Transitional Science Institute (KL-2 Award, PI Felson)
Grant NIAMS Multidisciplinary Clinical Research Center
Grant Ruth L. Kirschstein (NRSA) Institutional Research Training Grant (T32)
Grant Boston University Clinical and Translational Science Institute (Career Development)
Grant Boston University Clinical and Translational Science Institute (Career Development)
Grant The Boston University Clinical and Transitional Science Institute (Career Development)
Grant New Investigator Workshop on Advancing Arthritis Research
Grant Multidisciplinary Clinical Research Center at BU
Grant NIAMS Multidisciplinary Clinical Research Center
Academic Article Effect of Biomechanical Footwear on Knee Pain in People With Knee Osteoarthritis: The BIOTOK Randomized Clinical Trial.

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