Search Results to Hemant K. Roy, MD

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One or more keywords matched the following properties of Roy, Hemant

Research Expertise & Professional Interests Dr. Roy joined the faculty in 2013. He completed his medical degree from Northwestern University with distinction and completed internal medicine residency at Beth Isreal followed by GI Fellowship at University of Chicago. Dr. Roy’s research interests center on GI cancer risk stratification using intermediate biomarkers of field carcinogenesis. He has been involved in the development and clinical implementation of a variety of biophotonic techniques for risk stratification encompassing both fiberoptic probes and cytological based techniques and these are complemented by a variety of molecular markers including microRNAs. This has served as a platform for assessing risk modification via chemoprevention and applied to a number of non-GI malignancies including lung and ovarian cancer. Dr. Roy is a fellow of the American Gastroenterological Association and member of the Early Detection Research Network and the Cancer Biomarkers Study Section of the NCI, More clinically, his interests are in high risk colon cancer syndromes and role of gender in colorectal cancer screening. Throughout his career he has also been involved in teaching receiving numerous awards in this regard.
Self-Described Keywords High Risk Colon Cancer syndromes
Self-Described Keywords Role of gender in colorectal cancer screenings
Self-Described Keywords Non GI malignancies such as lung and ovarian cancer

One or more keywords matched the following items that are connected to Roy, Hemant

Item TypeName
Concept Biliary Tract Neoplasms
Concept Colonic Neoplasms
Concept Colorectal Neoplasms, Hereditary Nonpolyposis
Concept Duodenal Neoplasms
Concept Gastrointestinal Neoplasms
Concept Genital Neoplasms, Female
Concept Intestinal Neoplasms
Concept Liver Neoplasms
Concept Lung Neoplasms
Concept Mouth Neoplasms
Concept Neoplasm Invasiveness
Concept Neoplasm Metastasis
Concept Neoplasm Proteins
Concept Neoplasm Recurrence, Local
Concept Neoplasm Staging
Concept Neoplasms
Concept Neoplasms, Experimental
Concept Neoplasms, Multiple Primary
Concept Neoplasms, Radiation-Induced
Concept Ovarian Neoplasms
Concept Pancreatic Neoplasms
Concept Prostatic Neoplasms
Concept Rectal Neoplasms
Concept Stomach Neoplasms
Concept Tumor Cells, Cultured
Concept Biomarkers, Tumor
Concept Colorectal Neoplasms
Concept Antigens, Tumor-Associated, Carbohydrate
Concept Genes, Tumor Suppressor
Concept Neoplasms, Second Primary
Concept Drug Resistance, Neoplasm
Concept Cell Line, Tumor
Concept Early Detection of Cancer
Concept Neoplasm Grading
Academic Article Selective preservation of protein kinase C-zeta in the chemoprevention of azoxymethane-induced colonic tumors by piroxicam.
Academic Article Chemoprevention of azoxymethane-induced colonic carcinogenesis by supplemental dietary ursodeoxycholic acid.
Academic Article 1,25(OH)2 vitamin D3 activates PKC-alpha in Caco-2 cells: a mechanism to limit secosteroid-induced rise in [Ca2+]i.
Academic Article Colon cancer after gynecological cancer: guilt by association?
Academic Article Distal bowel selectivity in the chemoprevention of experimental colon carcinogenesis by the non-steroidal anti-inflammatory drug nabumetone.
Academic Article Chemoprevention of intestinal tumorigenesis by nabumetone: induction of apoptosis and Bcl-2 downregulation.
Academic Article Polyethylene glycol induces apoptosis in HT-29 cells: potential mechanism for chemoprevention of colon cancer.
Academic Article AKT proto-oncogene overexpression is an early event during sporadic colon carcinogenesis.
Academic Article Colorectal cancer screening compliance by medicine residents: perceived and actual.
Academic Article Ethanol promotes intestinal tumorigenesis in the MIN mouse. Multiple intestinal neoplasia.
Academic Article Diagnosing Lynch syndrome: is the answer in the mouth?
Academic Article Four-dimensional elastic light-scattering fingerprints as preneoplastic markers in the rat model of colon carcinogenesis.
Academic Article Increased cumulative incidence of prostate malignancies in colorectal cancer patients.
Academic Article Down-regulation of SNAIL suppresses MIN mouse tumorigenesis: modulation of apoptosis, proliferation, and fractal dimension.
Academic Article Polyethylene glycol inhibits intestinal neoplasia and induces epithelial apoptosis in Apc(min) mice.
Academic Article Tobacco use and increased colorectal cancer risk in patients with hereditary nonpolyposis colorectal cancer (Lynch syndrome).
Academic Article The nonsteroidal anti-inflammatory drug, nabumetone, differentially inhibits beta-catenin signaling in the MIN mouse and azoxymethane-treated rat models of colon carcinogenesis.
Academic Article The transcriptional repressor SNAIL is overexpressed in human colon cancer.
Academic Article Low-coherent backscattering spectroscopy for tissue characterization.
Academic Article Increased microvascular blood content is an early event in colon carcinogenesis.
Academic Article Depth-resolved low-coherence enhanced backscattering.
Academic Article Down-regulation of the tumor suppressor gene C-terminal Src kinase: an early event during premalignant colonic epithelial hyperproliferation.
Academic Article Spectral markers in preneoplastic intestinal mucosa: an accurate predictor of tumor risk in the MIN mouse.
Academic Article Assessment of blood supply in superficial tissue by polarization-gated elastic light-scattering spectroscopy.
Academic Article Risk stratification of colon carcinogenesis through enhanced backscattering spectroscopy analysis of the uninvolved colonic mucosa.
Academic Article Associations between the age at diagnosis and location of colorectal cancer and the use of alcohol and tobacco: implications for screening.
Academic Article The association between aspirin use and the incidence of colorectal cancer in women.
Academic Article Risk of colon cancer in hereditary non-polyposis colorectal cancer patients as predicted by fuzzy modeling: Influence of smoking.
Academic Article Chemoprevention of colon carcinogenesis by polyethylene glycol: suppression of epithelial proliferation via modulation of SNAIL/beta-catenin signaling.
Academic Article Low-coherence enhanced backscattering: review of principles and applications for colon cancer screening.
Academic Article Colon cancer screening: the good, the bad, and the ugly.
Academic Article Effect of dietary apigenin on colonic ornithine decarboxylase activity, aberrant crypt foci formation, and tumorigenesis in different experimental models.
Academic Article Low-coherence enhanced backscattering and its applications.
Academic Article Workshop on imaging science development for cancer prevention and preemption.
Academic Article Inducible nitric oxide synthase (iNOS) mediates the early increase of blood supply (EIBS) in colon carcinogenesis.
Academic Article Optical markers in duodenal mucosa predict the presence of pancreatic cancer.
Academic Article Biomarkers for the early detection of cancer: an inflammatory concept.
Academic Article Dysregulation of microRNAs in colonic field carcinogenesis: implications for screening.
Academic Article Purging the colon while preserving the kidneys.
Academic Article Spectral slope from the endoscopically-normal mucosa predicts concurrent colonic neoplasia: a pilot ex-vivo clinical study.
Academic Article Antiproliferative effect of sulindac in colonic neoplasia prevention: role of COOH-terminal Src kinase.
Academic Article Deregulation of MUC4 in gastric adenocarcinoma: potential pathobiological implication in poorly differentiated non-signet ring cell type gastric cancer.
Academic Article Optical methodology for detecting histologically unapparent nanoscale consequences of genetic alterations in biological cells.
Academic Article Partial-wave microscopic spectroscopy detects subwavelength refractive index fluctuations: an application to cancer diagnosis.
Academic Article Spectroscopic microvascular blood detection from the endoscopically normal colonic mucosa: biomarker for neoplasia risk.
Academic Article Polyethylene glycol-mediated colorectal cancer chemoprevention: roles of epidermal growth factor receptor and Snail.
Academic Article Colorectal cancer risk: black, white, or shades of gray?
Academic Article The MUC gene family: their role in the diagnosis and prognosis of gastric cancer.
Academic Article Optical spectroscopic markers of cancer.
Academic Article Investigating population risk factors of pancreatic cancer by evaluation of optical markers in the duodenal mucosa.
Academic Article Association between rectal optical signatures and colonic neoplasia: potential applications for screening.
Academic Article Rectal mucosal microvascular blood supply increase is associated with colonic neoplasia.
Academic Article Pancreatic cancer patients who smoke and drink are diagnosed at younger ages.
Academic Article Detecting alterations in cell ultrastructure with optical imaging.
Academic Article Association of colorectal cancer and prostate cancer and impact of radiation therapy.
Academic Article Nanoscale cellular changes in field carcinogenesis detected by partial wave spectroscopy.
Academic Article Differences in colon adenomas and carcinomas among women and men: potential clinical implications.
Academic Article Moving toward personalization of colorectal cancer screening: Comment on "Influence of race and sex on prevalence and recurrence of colon polyps".
Academic Article Light-scattering technologies for field carcinogenesis detection: a modality for endoscopic prescreening.
Academic Article Involvement of p21cip1/waf1 in the anti-proliferative effects of polyethylene glycol in colon carcinogenesis.
Academic Article Nanocytology for field carcinogenesis detection: novel paradigm for lung cancer risk stratification.
Academic Article Optical measurement of rectal microvasculature as an adjunct to flexible sigmoidosocopy: gender-specific implications.
Academic Article Optical detection of buccal epithelial nanoarchitectural alterations in patients harboring lung cancer: implications for screening.
Academic Article Tumor suppressor FOXO3 mediates signals from the EGF receptor to regulate proliferation of colonic cells.
Academic Article Neo-angiogenesis and the premalignant micro-circulatory augmentation of early colon carcinogenesis.
Academic Article Quantification of nanoscale density fluctuations by electron microscopy: probing cellular alterations in early carcinogenesis.
Academic Article Colonoscopy and optical biopsy: bridging technological advances to clinical practice.
Academic Article Association of stem-like cells in gender-specific chemoprevention against intestinal neoplasia in MIN mouse.
Academic Article Decreased colorectal cancer and adenoma risk in patients with microscopic colitis.
Academic Article Progress against cancer (1971-2011): how far have we come?
Academic Article Prospective analysis of association between use of statins or other lipid-lowering agents and colorectal cancer risk.
Academic Article Sex-specific prevalence of adenomas and colorectal cancer.
Academic Article In vivo measurement of the shape of the tissue-refractive-index correlation function and its application to detection of colorectal field carcinogenesis.
Academic Article Topical polyethylene glycol as a novel chemopreventive agent for oral cancer via targeting of epidermal growth factor response.
Academic Article APC gene testing for familial adenomatosis polyposis.
Academic Article Surveillance for gastrointestinal malignancies.
Academic Article Comprehensive review of the diagnosis and treatment of biliary tract cancer 2012. Part II: multidisciplinary management.
Academic Article Comprehensive review of the diagnosis and treatment of biliary tract cancer 2012. Part I: diagnosis-clinical staging and pathology.
Academic Article Nanocytology of rectal colonocytes to assess risk of colon cancer based on field cancerization.
Academic Article Spectroscopic applications in gastrointestinal endoscopy.
Academic Article Increasing colorectal cancer screening adherence: comment on "A randomized comparison of print and web communication on colorectal cancer screening".
Academic Article Biological mechanisms underlying structural changes induced by colorectal field carcinogenesis measured with low-coherence enhanced backscattering (LEBS) spectroscopy.
Academic Article Insights into the field carcinogenesis of ovarian cancer based on the nanocytology of endocervical and endometrial epithelial cells.
Academic Article Advances in biophotonics detection of field carcinogenesis for colon cancer risk stratification.
Academic Article FOXO3 growth inhibition of colonic cells is dependent on intraepithelial lipid droplet density.
Academic Article HDAC up-regulation in early colon field carcinogenesis is involved in cell tumorigenicity through regulation of chromatin structure.
Academic Article Ultrastructural alterations in field carcinogenesis measured by enhanced backscattering spectroscopy.
Academic Article Mechanism of action of chemoprotective ursodeoxycholate in the azoxymethane model of rat colonic carcinogenesis: potential roles of protein kinase C-alpha, -beta II, and -zeta.
Academic Article Nanoscale changes in chromatin organization represent the initial steps of tumorigenesis: a transmission electron microscopy study.
Academic Article Spatially resolved optical and ultrastructural properties of colorectal and pancreatic field carcinogenesis observed by inverse spectroscopic optical coherence tomography.
Academic Article Buccal spectral markers for lung cancer risk stratification.
Academic Article Rectal Optical Markers for In Vivo Risk Stratification of Premalignant Colorectal Lesions.
Academic Article Dysplasia and cancer screening in 21st century.
Academic Article Buccal microRNA dysregulation in lung field carcinogenesis: gender-specific implications.
Academic Article Polarization gating spectroscopy of normal-appearing duodenal mucosa to detect pancreatic cancer.
Academic Article In vivo risk analysis of pancreatic cancer through optical characterization of duodenal mucosa.
Academic Article End-binding protein 1 (EB1) up-regulation is an early event in colorectal carcinogenesis.
Academic Article Colonic mucosal fatty acid synthase as an early biomarker for colorectal neoplasia: modulation by obesity and gender.
Academic Article Nano-architectural alterations in mucus layer fecal colonocytes in field carcinogenesis: potential for screening.
Academic Article Nanocytological field carcinogenesis detection to mitigate overdiagnosis of prostate cancer: a proof of concept study.
Academic Article The genetics and molecular biology of colonic neoplasia: practical implications for the clinician.
Academic Article Spectral biomarkers for chemoprevention of colonic neoplasia: a placebo-controlled double-blinded trial with aspirin.
Academic Article Procedures for risk-stratification of lung cancer using buccal nanocytology.
Academic Article Mucins and associated O-glycans based immunoprofile for stratification of colorectal polyps: clinical implication for improved colon surveillance.
Academic Article Colon adenoma features and their impact on risk of future advanced adenomas and colorectal cancer.
Academic Article The Greater Genomic Landscape: The Heterogeneous Evolution of Cancer.
Academic Article Mice deficient in Muc4 are resistant to experimental colitis and colitis-associated colorectal cancer.
Academic Article Harnessing novel modalities: field carcinogenesis detection for personalizing prostate cancer management.
Academic Article Metabolic reprogramming of the premalignant colonic mucosa is an early event in carcinogenesis.
Academic Article Metabolism, microbiome and colorectal cancer.
Academic Article Higher Order Chromatin Modulator Cohesin SA1 Is an Early Biomarker for Colon Carcinogenesis: Race-Specific Implications.
Academic Article Identification of malignancy-associated change in buccal mucosa with partial wave spectroscopy (PWS): A potential biomarker for lung cancer risk.
Academic Article ASPirin Intervention for the REDuction of colorectal cancer risk (ASPIRED): a study protocol for a randomized controlled trial.
Academic Article Exercise-induced myokines as emerging therapeutic agents in colorectal cancer prevention and treatment.
Academic Article Single Nucleotide Polymorphism Facilitated Down-Regulation of the Cohesin Stromal Antigen-1: Implications for Colorectal Cancer Racial Disparities.
Academic Article Precision Medicine for CRC Patients in the Veteran Population: State-of-the-Art, Challenges and Research Directions.
Academic Article Correlating colorectal cancer risk with field carcinogenesis progression using partial wave spectroscopic microscopy.
Academic Article Prevention of colonic neoplasia with polyethylene glycol: A short term randomized placebo-controlled double-blinded trial.
Academic Article Biophotonic detection of high order chromatin alterations in field carcinogenesis predicts risk of future hepatocellular carcinoma: A pilot study.
Academic Article Early increase in blood supply (EIBS) is associated with tumor risk in the Azoxymethane model of colon cancer.

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