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Search Results to Tony E. Godfrey, PhD

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One or more keywords matched the following properties of Godfrey, Tony

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Research Expertise & Professional Interests Tony E. Godfrey, PhD, Associate Chair, Surgical Research and Associate Professor of Surgery, Boston University School of Medicine, earned a bachelor’s of science degree in biochemistry from Brunel University in England, followed by a doctorate in molecular biology and biochemistry, also from Brunel. He attended the University of California, San Francisco, for postdoctoral fellowships and managed UCSF’s Genome Analysis Core Facility. Most recently, Dr. Godfrey was a Research Associate Professor in the Department of Surgery at the University of Rochester Medical Center in Rochester, NY. Prior to this he was an Associate Professor of Pathology at Mt. Sinai School of Medicine in New York, NY. Dr. Godfrey’s research is focused on cancer genetics and molecular pathology. Research projects use state-of-the-art genetic and genomic approaches to address clinical needs in the areas of cancer diagnosis, prognosis and therapy. Currently the major focus of Dr. Godfrey’s research is on Barrett’s esophagus and esophageal adenocarcinoma; a tumor with rapidly increasing incidence in the United States and other western countries. The Godfrey lab works closely with translational research teams comprised of surgeons, pathologists and oncologists in order to develop new molecular approaches to cancer detection, staging and treatment.
Self-Described Keywords Translational cancer research
Self-Described Keywords Cancer Genomics
Self-Described Keywords Lung Cancer

One or more keywords matched the following items that are connected to Godfrey, Tony

Item TypeName
Concept Antigens, Neoplasm
Concept Brain Neoplasms
Concept Breast Neoplasms
Concept Colonic Neoplasms
Concept DNA, Neoplasm
Concept Esophageal Neoplasms
Concept Gastrointestinal Neoplasms
Concept Head and Neck Neoplasms
Concept Liver Neoplasms
Concept Lung Neoplasms
Concept Mouth Neoplasms
Concept Neoplasm Invasiveness
Concept Neoplasm Metastasis
Concept Neoplasm Proteins
Concept Neoplasm Recurrence, Local
Concept Neoplasm Staging
Concept Neoplasms
Concept Ovarian Neoplasms
Concept Prostatic Neoplasms
Concept RNA, Neoplasm
Concept Skin Neoplasms
Concept Stomach Neoplasms
Concept Thoracic Neoplasms
Concept Tumor Cells, Cultured
Concept Colorectal Neoplasms
Concept Genes, Tumor Suppressor
Concept Tumor Suppressor Protein p53
Concept Drug Resistance, Neoplasm
Concept Cell Line, Tumor
Concept Genes, Neoplasm
Concept Tumor Microenvironment
Concept Neoplasm Grading
Academic Article Mechanisms of inactivation of E-cadherin in breast cancer cell lines.
Academic Article Molecular cytogenetic analysis of consistent abnormalities at 8q12-q22 in breast cancer.
Academic Article Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma.
Academic Article PIK3CA is implicated as an oncogene in ovarian cancer.
Academic Article Whole genome amplification and molecular genetic analysis of DNA from paraffin-embedded prostate adenocarcinoma tumor tissue.
Academic Article Genome-wide screen for allelic imbalance in a mouse model for neuroblastoma.
Academic Article Validation of fluorescent SSCP analysis for sensitive detection of p53 mutations.
Academic Article Analysis of complex relationships between age, p53, epidermal growth factor receptor, and survival in glioblastoma patients.
Academic Article Gene amplifications characterize acral melanoma and permit the detection of occult tumor cells in the surrounding skin.
Academic Article An approach to analysis of large-scale correlations between genome changes and clinical endpoints in ovarian cancer.
Academic Article Measurement of DNA copy number at microsatellite loci using quantitative PCR analysis.
Academic Article Correlation between dysplasia and mutations of six tumor suppressor genes in Barrett's esophagus.
Academic Article Prognostic value of quantitative reverse transcription-polymerase chain reaction in lymph node-negative esophageal cancer patients.
Academic Article Real-time quantitative polymerase chain reaction: a potential tool for genetic analysis in neuropathology.
Academic Article Rapid, quantitative reverse transcriptase-polymerase chain reaction: application to intraoperative molecular detection of occult metastases in esophageal cancer.
Academic Article Temperature-controlled primer limit for multiplexing of rapid, quantitative reverse transcription-PCR assays: application to intraoperative cancer diagnostics.
Academic Article High-resolution mapping of the 11q13 amplicon and identification of a gene, TAOS1, that is amplified and overexpressed in oral cancer cells.
Academic Article The role of tumor suppressor genes in esophageal cancer.
Academic Article Identification of genetic alterations related to chemoresistance in epithelial ovarian cancer.
Academic Article Prognostic significance of micrometastasis in non-small-cell lung cancer.
Academic Article Tests for finding complex patterns of differential expression in cancers: towards individualized medicine.
Academic Article Characterization of amplifiable, circulating RNA in plasma and its potential as a tool for cancer diagnostics.
Academic Article Expression pattern of chemokine receptor 6 (CCR6) and CCR7 in squamous cell carcinoma of the head and neck identifies a novel metastatic phenotype.
Academic Article Quantitative analysis of circulating plasma DNA as a tumor marker in thoracic malignancies.
Academic Article Chemokine receptors 6 and 7 identify a metastatic expression pattern in squamous cell carcinoma of the head and neck.
Academic Article Molecular staging of lymph nodes from patients with esophageal adenocarcinoma.
Academic Article The HGF receptor c-Met is overexpressed in esophageal adenocarcinoma.
Academic Article Workshop on cancer biometrics: identifying biomarkers and surrogates of cancer in patients: a meeting held at the Masur Auditorium, National Institutes of Health.
Academic Article Technology for automated, rapid, and quantitative PCR or reverse transcription-PCR clinical testing.
Academic Article Molecular staging of cervical lymph nodes in squamous cell carcinoma of the head and neck.
Academic Article Recent thymic emigrants and subsets of naive and memory T cells in the circulation of patients with head and neck cancer.
Academic Article Prediction of lymph node metastasis by analysis of gene expression profiles in primary lung adenocarcinomas.
Academic Article A rapid, fully automated, molecular-based assay accurately analyzes sentinel lymph nodes for the presence of metastatic breast cancer.
Academic Article Identification of mRNA markers for molecular staging of lymph nodes in colorectal cancer.
Academic Article A combination of molecular markers accurately detects lymph node metastasis in non-small cell lung cancer patients.
Academic Article Comprehensive genome and transcriptome analysis of the 11q13 amplicon in human oral cancer and synteny to the 7F5 amplicon in murine oral carcinoma.
Academic Article Is occult lymph node disease in colorectal cancer patients clinically significant? A review of the relevant literature.
Academic Article MicroRNA expression profiles of esophageal cancer.
Academic Article Optimal markers for real-time quantitative reverse transcription PCR detection of circulating tumor cells from melanoma, breast, colon, esophageal, head and neck, and lung cancers.
Academic Article Whole genome exon arrays identify differential expression of alternatively spliced, cancer-related genes in lung cancer.
Academic Article Association between CCND1 G/A870 polymorphism, allele-specific amplification, cyclin D1 expression, and survival in esophageal and lung carcinoma.
Academic Article Molecular staging of pathologically negative sentinel lymph nodes from melanoma patients using multimarker, quantitative real-time rt-PCR.
Academic Article Quantitative expression and immunogenicity of MAGE-3 and -6 in upper aerodigestive tract cancer.
Academic Article A quantitative reverse transcription-PCR assay for rapid, automated analysis of breast cancer sentinel lymph nodes.
Academic Article Early G1 cyclin-dependent kinases as prognostic markers and potential therapeutic targets in esophageal adenocarcinoma.
Academic Article Micro RNA expression profiles as adjunctive data to assess the risk of hepatocellular carcinoma recurrence after liver transplantation.
Academic Article Intraoperative qRT-PCR for detection of lymph node metastasis in head and neck cancer.
Academic Article MicroRNA prognostic signature for nodal metastases and survival in esophageal adenocarcinoma.
Academic Article HER2 amplification, overexpression and score criteria in esophageal adenocarcinoma.
Academic Article Rapid molecular detection of metastatic head and neck squamous cell carcinoma as an intraoperative adjunct to sentinel lymph node biopsy.
Academic Article Comparative genomics of esophageal adenocarcinoma and squamous cell carcinoma.
Academic Article Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis.
Academic Article Clinicopathologic characteristics of high expression of Bmi-1 in esophageal adenocarcinoma and squamous cell carcinoma.
Academic Article Gene expression profiles in esophageal adenocarcinoma predict survival after resection.
Academic Article Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity.
Academic Article Correlation of tumor marker expression with nodal disease burden in metastatic head and neck cancer.
Academic Article Bile acid at low pH reduces squamous differentiation and activates EGFR signaling in esophageal squamous cells in 3-D culture.
Academic Article Vitamin D receptor is highly expressed in precancerous lesions and esophageal adenocarcinoma with significant sex difference.
Academic Article Comparison of cancer-associated genetic abnormalities in columnar-lined esophagus tissues with and without goblet cells.
Academic Article Properties of targeted preamplification in DNA and cDNA quantification.
Academic Article Cyclin E involved in early stage carcinogenesis of esophageal adenocarcinoma by SNP DNA microarray and immunohistochemical studies.
Academic Article Multiplex Preamplification of Serum DNA to Facilitate Reliable Detection of Extremely Rare Cancer Mutations in Circulating DNA by Digital PCR.
Academic Article Allelic imbalance mapping of chromosome 16 shows two regions of common deletion in prostate adenocarcinoma.
Academic Article Plasma circulating tumor DNA as a potential tool for disease monitoring in head and neck cancer.
Academic Article Considerations and quality controls when analyzing cell-free tumor DNA.
Academic Article The Molecular Biologic Basis of Esophageal and Gastric Cancers.
Academic Article Multilaboratory Assessment of a New Reference Material for Quality Assurance of Cell-Free Tumor DNA Measurements.
Academic Article Detection of Circulating Tumor DNA in Plasma: A Potential Biomarker for Esophageal Adenocarcinoma.
Academic Article Corrigendum to "Considerations and quality controls when analyzing cell-free tumor DNA" [Biomol. Detect. Quantif. 17 (2019) 100078].

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  • neoplasms