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Search Results to David J. Waxman, PhD

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One or more keywords matched the following items that are connected to Waxman, David

Item TypeName
Concept Transcription Factors
Concept STAT1 Transcription Factor
Concept STAT3 Transcription Factor
Concept STAT5 Transcription Factor
Academic Article Dehydroepiandrosterone sulfate and beta-cell function: enhanced glucose-induced insulin secretion and altered gene expression in rodent pancreatic beta-cells.
Academic Article Environmental and endogenous peroxisome proliferator-activated receptor gamma agonists induce bone marrow B cell growth arrest and apoptosis: interactions between mono(2-ethylhexyl)phthalate, 9-cis-retinoic acid, and 15-deoxy-Delta12,14-prostaglandin J2.
Academic Article Male-specific hepatic Bcl6: growth hormone-induced block of transcription elongation in females and binding to target genes inversely coordinated with STAT5.
Academic Article Sex-dependent liver gene expression is extensive and largely dependent upon signal transducer and activator of transcription 5b (STAT5b): STAT5b-dependent activation of male genes and repression of female genes revealed by microarray analysis.
Academic Article STAT5 signaling in sexually dimorphic gene expression and growth patterns.
Academic Article Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression.
Academic Article Interaction of growth hormone-activated STATs with SH2-containing phosphotyrosine phosphatase SHP-1 and nuclear JAK2 tyrosine kinase.
Academic Article Role of hepatocyte nuclear factors in growth hormone-regulated, sexually dimorphic expression of liver cytochromes P450.
Academic Article STAT5b-deficient mice are growth hormone pulse-resistant. Role of STAT5b in sex-specific liver p450 expression.
Academic Article SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms.
Academic Article Dynamic, sex-differential STAT5 and BCL6 binding to sex-biased, growth hormone-regulated genes in adult mouse liver.
Academic Article Loss of sexually dimorphic liver gene expression upon hepatocyte-specific deletion of Stat5a-Stat5b locus.
Academic Article Interaction of a novel sex-dependent, growth hormone-regulated liver nuclear factor with CYP2C12 promoter.
Academic Article Synergistic action of hepatocyte nuclear factors 3 and 6 on CYP2C12 gene expression and suppression by growth hormone-activated STAT5b. Proposed model for female specific expression of CYP2C12 in adult rat liver.
Academic Article Signalling cross-talk between hepatocyte nuclear factor 4alpha and growth-hormone-activated STAT5b.
Academic Article Plasma growth hormone pulse activation of hepatic JAK-STAT5 signaling: developmental regulation and role in male-specific liver gene expression.
Academic Article trans-Activation of PPARalpha and PPARgamma by structurally diverse environmental chemicals.
Academic Article Growth hormone pulse-activated STAT5 signalling: a unique regulatory mechanism governing sexual dimorphism of liver gene expression.
Academic Article STAT5b is required for GH-induced liver IGF-I gene expression.
Academic Article Serine phosphorylation of GH-activated signal transducer and activator of transcription 5a (STAT5a) and STAT5b: impact on STAT5 transcriptional activity.
Academic Article Impact of CUX2 on the female mouse liver transcriptome: activation of female-biased genes and repression of male-biased genes.
Academic Article Down-regulation of liver JAK2-STAT5b signaling by the female plasma pattern of continuous growth hormone stimulation.
Academic Article Down-regulation of STAT5b transcriptional activity by ligand-activated peroxisome proliferator-activated receptor (PPAR) alpha and PPARgamma.
Academic Article STAT5b down-regulates peroxisome proliferator-activated receptor alpha transcription by inhibition of ligand-independent activation function region-1 trans-activation domain.
Academic Article Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis.
Academic Article Regulation of signal transducer and activator of transcription (STAT) 5b activation by the temporal pattern of growth hormone stimulation.
Academic Article Growth hormone regulation of sex-dependent liver gene expression.
Academic Article Impact of dimethyl sulfoxide on expression of nuclear receptors and drug-inducible cytochromes P450 in primary rat hepatocytes.
Academic Article Activation of PPARalpha and PPARgamma by environmental phthalate monoesters.
Academic Article Dynamic in vivo binding of STAT5 to growth hormone-regulated genes in intact rat liver. Sex-specific binding at low- but not high-affinity STAT5 sites.
Academic Article Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption.
Academic Article Simultaneous, bidirectional inhibitory crosstalk between PPAR and STAT5b.
Academic Article Growth hormone, but not prolactin, maintains, low-level activation of STAT5a and STAT5b in female rat liver.
Academic Article Characterization of three growth hormone-responsive transcription factors preferentially expressed in adult female liver.
Academic Article Temporal relationship between the sexually dimorphic spontaneous GH secretory profiles and hepatic STAT5 activity.
Academic Article Cross Talk Between GH-Regulated Transcription Factors HNF6 and CUX2 in Adult Mouse Liver.
Academic Article Activation of Male Liver Chromatin Accessibility and STAT5-Dependent Gene Transcription by Plasma Growth Hormone Pulses.
Academic Article Loss of growth hormone-mediated signal transducer and activator of transcription 5 (STAT5) signaling in mice results in insulin sensitivity with obesity.
Academic Article Sexually dimorphic P450 gene expression in liver-specific hepatocyte nuclear factor 4alpha-deficient mice.
Academic Article P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.
Academic Article Role of the cytokine-induced SH2 domain-containing protein CIS in growth hormone receptor internalization.
Academic Article Unbiased, genome-wide in vivo mapping of transcriptional regulatory elements reveals sex differences in chromatin structure associated with sex-specific liver gene expression.
Academic Article Role of hepatocyte nuclear factors in transcriptional regulation of male-specific CYP2A2.
Academic Article Intermittent plasma growth hormone triggers tyrosine phosphorylation and nuclear translocation of a liver-expressed, Stat 5-related DNA binding protein. Proposed role as an intracellular regulator of male-specific liver gene transcription.
Academic Article Peroxisome proliferator-activated receptor alpha required for gene induction by dehydroepiandrosterone-3 beta-sulfate.
Academic Article MAnorm: a robust model for quantitative comparison of ChIP-Seq data sets.
Academic Article Role of the cytokine-inducible SH2 protein CIS in desensitization of STAT5b signaling by continuous growth hormone.
Academic Article Growth hormone receptor cytoplasmic domain differentially promotes tyrosine phosphorylation of signal transducers and activators of transcription 5b and 3 by activated JAK2 kinase.
Academic Article Genome-wide analysis of chromatin states reveals distinct mechanisms of sex-dependent gene regulation in male and female mouse liver.
Academic Article Growth hormone activation of Stat 1, Stat 3, and Stat 5 in rat liver. Differential kinetics of hormone desensitization and growth hormone stimulation of both tyrosine phosphorylation and serine/threonine phosphorylation.
Academic Article Multiple, functional DBP sites on the promoter of the cholesterol 7 alpha-hydroxylase P450 gene, CYP7. Proposed role in diurnal regulation of liver gene expression.
Academic Article Codependence of growth hormone-responsive, sexually dimorphic hepatic gene expression on signal transducer and activator of transcription 5b and hepatic nuclear factor 4alpha.
Academic Article Functional Roles of Sex-Biased, Growth Hormone-Regulated MicroRNAs miR-1948 and miR-802 in Young Adult Mouse Liver.
Academic Article Chemical and Hormonal Effects on STAT5b-Dependent Sexual Dimorphism of the Liver Transcriptome.
Academic Article Disruption of STAT5b-Regulated Sexual Dimorphism of the Liver Transcriptome by Diverse Factors Is a Common Event.
Academic Article Inhibitory cross-talk between STAT5b and liver nuclear factor HNF3beta: impact on the regulation of growth hormone pulse-stimulated, male-specific liver cytochrome P-450 gene expression.
Academic Article Activation of peroxisome proliferator-activated receptors by chlorinated hydrocarbons and endogenous steroids.
Academic Article Termination of growth hormone pulse-induced STAT5b signaling.
Academic Article Cross-talk between janus kinase-signal transducer and activator of transcription (JAK-STAT) and peroxisome proliferator-activated receptor-alpha (PPARalpha) signaling pathways. Growth hormone inhibition of pparalpha transcriptional activity mediated by stat5b.
Academic Article Elevated basal expression of liver peroxisomal beta-oxidation enzymes and CYP4A microsomal fatty acid omega-hydroxylase in STAT5b(-/-) mice: cross-talk in vivo between peroxisome proliferator-activated receptor and signal transducer and activator of transcription signaling pathways.
Academic Article Synthetic drugs and natural products as modulators of constitutive androstane receptor (CAR) and pregnane X receptor (PXR).

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