Search Results to David J. Waxman, PhD

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Research Expertise & Professional Interests David J. Waxman, PhD is a Biologist with extensive experience in the fields of biochemistry, molecular biology, and enzymology. Over the past 35 years, his lab has made seminal contributions to the research of cancer pharmacology and therapeutics, and steroid-metabolizing enzymes. Dr. Waxman has spoken at over 130 conferences and has held appointments at a variety of universities including Harvard Medical School, MIT, and the Weizmann Institute.

One or more keywords matched the following items that are connected to Waxman, David

Item TypeName
Concept Models, Structural
Concept Magnetic Resonance Spectroscopy
Concept Spectrum Analysis
Concept Computational Biology
Academic Article Wavelength-dependent backscattering measurements for quantitative monitoring of apoptosis, part 1: early and late spectral changes are indicative of the presence of apoptosis in cell cultures.
Academic Article Wavelength-dependent backscattering measurements for quantitative monitoring of apoptosis, part 2: early spectral changes during apoptosis are linked to apoptotic volume decrease.
Academic Article The structural basis of pregnane X receptor binding promiscuity.
Academic Article Differential apoprotein loss of rat liver cytochromes P450 after their inactivation by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine: a case for distinct proteolytic mechanisms?
Academic Article trans-Activation of PPARalpha and PPARgamma by structurally diverse environmental chemicals.
Academic Article Participation of two structurally related enzymes in rat hepatic microsomal androstenedione 7 alpha-hydroxylation.
Academic Article Detoxification of lithocholic acid. Elucidation of the pathways of oxidative metabolism in rat liver microsomes.
Academic Article Computational screening of phthalate monoesters for binding to PPARgamma.
Academic Article Cytochrome P-450 cholesterol 7 alpha-hydroxylase: inhibition of enzyme deactivation by structurally diverse calmodulin antagonists and phosphatase inhibitors.
Academic Article P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.
Academic Article Exploring the binding site structure of the PPAR gamma ligand-binding domain by computational solvent mapping.
Academic Article Chemical and Hormonal Effects on STAT5b-Dependent Sexual Dimorphism of the Liver Transcriptome.
Academic Article Computational solvent mapping reveals the importance of local conformational changes for broad substrate specificity in mammalian cytochromes P450.

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  • spectroscopy