Search Results to David J. Waxman, PhD

This is a "connection" page, showing the details of why an item matched the keywords from your search.


One or more keywords matched the following items that are connected to Waxman, David

Item TypeName
Concept Genetic Therapy
Academic Article Experimental tumor therapy in mice using the cyclophosphamide-activating cytochrome P450 2B1 gene.
Academic Article Retroviral transfer of human cytochrome P450 genes for oxazaphosphorine-based cancer gene therapy.
Academic Article Harnessing apoptosis for improved anticancer gene therapy.
Academic Article Frequent, moderate-dose cyclophosphamide administration improves the efficacy of cytochrome P-450/cytochrome P-450 reductase-based cancer gene therapy.
Academic Article Enhancement of intratumoral cyclophosphamide pharmacokinetics and antitumor activity in a P450 2B11-based cancer gene therapy model.
Academic Article Potentiation of cytochrome P450/cyclophosphamide-based cancer gene therapy by coexpression of the P450 reductase gene.
Academic Article Progress and prospects: gene therapy clinical trials (part 2).
Academic Article Collaboration between hepatic and intratumoral prodrug activation in a P450 prodrug-activation gene therapy model for cancer treatment.
Academic Article Cancer chemotherapy and drug metabolism.
Academic Article Impact of liver P450 reductase suppression on cyclophosphamide activation, pharmacokinetics and antitumoral activity in a cytochrome P450-based cancer gene therapy model.
Academic Article Combination of the bioreductive drug tirapazamine with the chemotherapeutic prodrug cyclophosphamide for P450/P450-reductase-based cancer gene therapy.
Academic Article Intratumoral activation and enhanced chemotherapeutic effect of oxazaphosphorines following cytochrome P-450 gene transfer: development of a combined chemotherapy/cancer gene therapy strategy.
Academic Article Modulation of cyclophosphamide-based cytochrome P450 gene therapy using liver P450 inhibitors.
Academic Article Cytochrome P450-based cancer gene therapy: recent advances and future prospects.
Academic Article Sustained P450 expression and prodrug activation in bolus cyclophosphamide-treated cultured tumor cells. Impact of prodrug schedule on P450 gene-directed enzyme prodrug therapy.
Academic Article Potentiation of methoxymorpholinyl doxorubicin antitumor activity by P450 3A4 gene transfer.
Academic Article Selection of cytochrome p450 genes for use in prodrug activation-based cancer gene therapy.
Academic Article 7 in vitro methods for evaluation of p450-based anticancer gene therapy.
Academic Article 8 tumor models for evaluation of p450 gene therapy in vivo.
Academic Article Enhanced antitumor activity of P450 prodrug-based gene therapy using the low Km cyclophosphamide 4-hydroxylase P450 2B11.
Academic Article Cytochrome p450-based gene therapies for cancer.
Academic Article Adenoviral vectors for prodrug activation-based gene therapy for cancer.
Academic Article Activation of oxazaphosphorines by cytochrome P450: application to gene-directed enzyme prodrug therapy for cancer.
Academic Article Adenoviral delivery of pan-caspase inhibitor p35 enhances bystander killing by P450 gene-directed enzyme prodrug therapy using cyclophosphamide+.
Academic Article Enhanced bystander cytotoxicity of P450 gene-directed enzyme prodrug therapy by expression of the antiapoptotic factor p35.
Academic Article Identification of novel enzyme-prodrug combinations for use in cytochrome P450-based gene therapy for cancer.

Search Criteria
  • gene therapy