Search Results to Ronald J. Killiany, PhD

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Research Expertise & Professional Interests The underlying theme of my research has been to explore structure – function relationships in the brain. To this end, my work has focused on uncovering the morphological changes in the brain that are responsible for the cognitive decline seen in aging and disease processes. In initial studies, I used developmental techniques to examine specific structure-function relationships in the memory system of non-human primates. I continued on to conduct studies of normal aging and cerebrovascular disease. In this work I have focused on characterize the cognitive changes taking place in non-human primate models. As my interests in studying the brain grew, I become involved in structural Magnetic Resonance Imaging (MRI) studies of normal aging and disorders such as Alzheimer’s disease. In this work I have been quantifying volumetric changes taking place in the brain in the course of the disease processes. This work continues to evolve and has changed focus somewhat in the recent years to include studies aimed at exploring the value of MRI in predicting which subjects will progress to develop cognitive decline and Alzheimer’s disease and which will remain cognitively stable.

One or more keywords matched the following items that are connected to Killiany, Ronald

Item TypeName
Concept Alzheimer Disease
Academic Article Temporal lobe regions on magnetic resonance imaging identify patients with early Alzheimer's disease.
Academic Article Use of structural magnetic resonance imaging to predict who will get Alzheimer's disease.
Academic Article MRI measures of entorhinal cortex vs hippocampus in preclinical AD.
Academic Article Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain.
Academic Article MRI-guided SPECT perfusion measures and volumetric MRI in prodromal Alzheimer disease.
Academic Article Structural magnetic resonance imaging in established and prodromal Alzheimer disease: a review.
Academic Article Medial temporal lobe function and structure in mild cognitive impairment.
Academic Article Progression of atrophy in Alzheimer's disease.
Academic Article An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest.
Academic Article Intensity non-uniformity correction using N3 on 3-T scanners with multichannel phased array coils.
Academic Article Spatial distribution of white-matter hyperintensities in Alzheimer disease, cerebral amyloid angiopathy, and healthy aging.
Academic Article The Alzheimer's Disease Neuroimaging Initiative (ADNI): MRI methods.
Academic Article An MRI study of age-related white and gray matter volume changes in the rhesus monkey.
Academic Article MRI measures of temporoparietal regions show differential rates of atrophy during prodromal AD.
Academic Article Temporoparietal MR imaging measures of atrophy in subjects with mild cognitive impairment that predict subsequent diagnosis of Alzheimer disease.
Academic Article Subregional neuroanatomical change as a biomarker for Alzheimer's disease.
Academic Article Isn't amyloid more than just a marker for Alzheimer disease?
Academic Article Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional-executive network function in Alzheimer's disease.
Academic Article Whole brain quantitative T2 MRI across multiple scanners with dual echo FSE: applications to AD, MCI, and normal aging.
Academic Article Update on the magnetic resonance imaging core of the Alzheimer's disease neuroimaging initiative.
Academic Article Subregions of the inferior parietal lobule are affected in the progression to Alzheimer''s disease.
Academic Article Alzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults.
Academic Article Hippocampal subregions are differentially affected in the progression to Alzheimer's disease.
Academic Article Survey of protocols for the manual segmentation of the hippocampus: preparatory steps towards a joint EADC-ADNI harmonized protocol.
Academic Article Standardization of analysis sets for reporting results from ADNI MRI data.
Academic Article The EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance: evidence of validity.
Academic Article It is unclear if adjusting cortical thickness for changes in gray/white matter intensity ratio improves discrimination between normal aging, MCI, and AD.
Academic Article Magnetic resonance imaging in Alzheimer''s Disease Neuroimaging Initiative 2.
Academic Article Delphi definition of the EADC-ADNI Harmonized Protocol for hippocampal segmentation on magnetic resonance.
Academic Article Comparison of ApoE-related brain connectivity differences in early MCI and normal aging populations: an fMRI study.
Academic Article Entorhinal Cortex: Antemortem Cortical Thickness and Postmortem Neurofibrillary Tangles and Amyloid Pathology.
Academic Article Seed Location Impacts Whole-Brain Structural Network Comparisons between Healthy Elderly and Individuals with Alzheimer''s Disease.
Academic Article Multimodal Discrimination between Normal Aging, Mild Cognitive Impairment and Alzheimer''s Disease and Prediction of Cognitive Decline.
Academic Article A Clinicopathological Investigation of White Matter Hyperintensities and Alzheimer''s Disease Neuropathology.
Academic Article Failure to detect an association between self-reported traumatic brain injury and Alzheimer''s disease neuropathology and dementia.
Academic Article Independent effects of white matter hyperintensities on cognitive, neuropsychiatric, and functional decline: a longitudinal investigation using the National Alzheimer''s Coordinating Center Uniform Data Set.
Academic Article A longitudinal examination of plasma neurofilament light and total tau for the clinical detection and monitoring of Alzheimer''s disease.
Grant Alzheimer's Disease Neuroimaging Initiative 2 (ADNI2)
Grant Vielight Neuro RX Gamma Photobiomodulation Device for Moderate to Severe Alzheimer's Disease
Grant Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3)
Grant ADNI-DOD-TAU, Effects of Traumatic Brain Injury and Post-Traumatic Stress Disorder and Alzheimer's Disease on Brain Tau in Vietnam Veterans using ADNI

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  • Alzheimer Disease