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Research Expertise & Professional Interests 72 East Concord Street, K-503, Boston, MA 02118 820 Harrison Avenue, Boston, MA 02118 (clinic address) Expertise includes: AL amyloidosis - clinical trials, treatment; Amyloidosis; Stem cell transplantation; Myeloma. Dr Vaishali Sanchorawala is the Director of Stem Cell Transplantation program at Boston Medical Center; Director of Amyloidosis Center at Boston University School of Medicine; Skinner Professor of Amyloidosis Research in the Department of Medicine; Associate Editor of Amyloid: The Journal of Protein Folding Disorders and Secretary of the International Society of Amyloidosis for the term 2020-2022. Her research has led and defined the field in AL amyloidosis. She is recognized as one of the leading international experts and a key opinion leader in amyloidosis. With numerous publications and meeting presentations, she is one of the pioneers in the field of clinical research in AL amyloidosis. Her work in the treatment of AL amyloidosis has resulted in the evolution of the standard of care for these patients. I am currently heading several clinical trials in the treatment of AL amyloidosis, two of which were conducted nationally through the Southwest Oncology Group (SWOG0115 and SWOG1702), completed accrual in a timely fashion and led to publications in a peer-reviewed journals. Dr Sanchorawala is part of the faculty at major international conferences in amyloidosis and has given many invited talks at national and international meetings. She is active in various non-profit organizations, regulatory authorities, and funding bodies as an expert on amyloidosis. She is at present a member of the Executive Steering Committee of Amyloidosis Research Consortium which is developing pathways to education, patient voice, development of treatment and access to novel therapies. She has participated in meetings with the FDA for enhancing the amyloidosis drug development pathway, guidance for more efficient and successful programs. She serves on the advisory board of number of leading pharmaceutical partners for drugs in AL amyloidosis. She has helped to create and cultivate the next generation of physician-scientists in the area of clinical research in amyloidosis. She regularly attends a number of patient information seminars and support group meetings in the US. She also created the first “live tweet event” for patients and care givers to ask questions via social media. Outside of roles of direct research and clinical care, she has an interest inworking in charity organizations. She helps cook meals for ~300 underserved individuals at a meal center in Massachusetts (1-2 times a month) and volunteers regularly at “Cradles to Crayons” charity, non-profit organization.
Self-Described Keywords Amyloidosis [C18.452.845.500]

One or more keywords matched the following items that are connected to Sanchorawala, Vaishali

Item TypeName
Concept Alanine
Concept Alcohol Drinking
Concept Algorithms
Concept Alkaline Phosphatase
Concept Alkylating Agents
Concept Amyloidosis
Concept Serum Albumin
Concept Antineoplastic Agents, Alkylating
Academic Article Intermediate-dose intravenous melphalan and blood stem cells mobilized with sequential GM+G-CSF or G-CSF alone to treat AL (amyloid light chain) amyloidosis.
Academic Article Dose-intensive melphalan with blood stem-cell support for the treatment of AL (amyloid light-chain) amyloidosis: survival and responses in 25 patients.
Academic Article Effect of dose-intensive intravenous melphalan and autologous blood stem-cell transplantation on al amyloidosis-associated renal disease.
Academic Article Acquired factor X deficiency in patients with amyloid light-chain amyloidosis: incidence, bleeding manifestations, and response to high-dose chemotherapy.
Academic Article High-dose intravenous melphalan with autologous stem cell transplantation in AL amyloidosis-associated end-stage renal disease.
Academic Article An overview of the use of high-dose melphalan with autologous stem cell transplantation for the treatment of AL amyloidosis.
Academic Article Immunologic recovery after autologous blood stem cell transplantation in patients with AL-amyloidosis.
Academic Article Low-dose continuous oral melphalan for the treatment of primary systemic (AL) amyloidosis.
Academic Article Tolerability and efficacy of thalidomide for the treatment of patients with light chain-associated (AL) amyloidosis.
Academic Article Incidence and outcome of acute renal failure complicating autologous stem cell transplantation for AL amyloidosis.
Academic Article Spontaneous rupture of the spleen in AL amyloidosis.
Academic Article High-dose melphalan and autologous stem-cell transplantation in patients with AL amyloidosis: an 8-year study.
Academic Article Persistent pleural effusions in primary systemic amyloidosis: etiology and prognosis.
Academic Article High-dose intravenous melphalan and autologous stem cell transplantation as initial therapy or following two cycles of oral chemotherapy for the treatment of AL amyloidosis: results of a prospective randomized trial.
Academic Article Improvement in quality of life of patients with AL amyloidosis treated with high-dose melphalan and autologous stem cell transplantation.
Academic Article Predictive factors for hematopoietic engraftment after autologous peripheral blood stem cell transplantation for AL amyloidosis.
Academic Article Serum free light-chain responses after high-dose intravenous melphalan and autologous stem cell transplantation for AL (primary) amyloidosis.
Academic Article Definition of organ involvement and treatment response in immunoglobulin light chain amyloidosis (AL): a consensus opinion from the 10th International Symposium on Amyloid and Amyloidosis, Tours, France, 18-22 April 2004.
Academic Article Diaphragm paralysis in primary systemic amyloidosis.
Academic Article Quantitative serum free light chain assay in the diagnostic evaluation of AL amyloidosis.
Academic Article Lenalidomide and dexamethasone in the treatment of AL amyloidosis: results of a phase 2 trial.
Academic Article Association of acquired von Willebrand syndrome with AL amyloidosis.
Academic Article AL amyloidosis associated with B-cell lymphoproliferative disorders: frequency and treatment outcomes.
Academic Article Successful treatment of AL amyloidosis with high-dose melphalan and autologous stem cell transplantation in patients over age 65.
Academic Article Adapting to AL amyloidosis.
Academic Article Tandem cycles of high-dose melphalan and autologous stem cell transplantation increases the response rate in AL amyloidosis.
Academic Article Long-term outcome of patients with AL amyloidosis treated with high-dose melphalan and stem-cell transplantation.
Academic Article Light-chain (AL) amyloidosis: diagnosis and treatment.
Academic Article An overview of high-dose melphalan and stem cell transplantation in the treatment of AL amyloidosis.
Academic Article Febrile reactions occurring with second cycle of high-dose melphalan and SCT in patients with AL amyloidosis: a 'melphalan recall' reaction.
Academic Article Hepatic response after high-dose melphalan and stem cell transplantation in patients with AL amyloidosis associated liver disease.
Academic Article Weekly and twice-weekly bortezomib in patients with systemic AL amyloidosis: results of a phase 1 dose-escalation study.
Academic Article Short and long-term outcome of treatment with high-dose melphalan and stem cell transplantation for multiple myeloma-associated AL amyloidosis.
Academic Article Cardiac transplantation followed by dose-intensive melphalan and autologous stem-cell transplantation for light chain amyloidosis and heart failure.
Academic Article Spontaneous rupture of the liver in a patient with systemic AL amyloidosis undergoing treatment with high-dose melphalan and autologous stem cell transplantation: a case report with literature review.
Academic Article Kidney dysfunction during lenalidomide treatment for AL amyloidosis.
Academic Article Durable hematologic complete responses can be achieved with lenalidomide in AL amyloidosis.
Academic Article A second course of high-dose melphalan and auto-SCT for the treatment of relapsed AL amyloidosis.
Academic Article Increases in B-type natriuretic peptide (BNP) during treatment with lenalidomide in AL amyloidosis.
Academic Article Oral cyclic melphalan and dexamethasone for patients with AL amyloidosis.
Academic Article Macroglossia - not always AL amyloidosis.
Academic Article Localized amyloidosis of the breast: a case series.
Academic Article Myocardial infarction with "clean coronaries" caused by amyloid light-chain AL amyloidosis: a case report and literature review.
Academic Article Efficacy and safety of once-weekly and twice-weekly bortezomib in patients with relapsed systemic AL amyloidosis: results of a phase 1/2 study.
Academic Article Cardiac amyloidosis: evolving approach to diagnosis and management.
Academic Article Amyloidotic cardiomyopathy: multidisciplinary approach to diagnosis and treatment.
Academic Article Bortezomib in a phase 1 trial for patients with relapsed AL amyloidosis: cardiac responses and overall effects.
Academic Article Outcome of AL amyloidosis after high-dose melphalan and autologous stem cell transplantation: long-term results in a series of 421 patients.
Academic Article High-dose melphalan and autologous stem cell transplantation for AL amyloidosis: recent trends in treatment-related mortality and 1-year survival at a single institution.
Academic Article Regression of cardiac wall thickness following chemotherapy and stem cell transplantation for light chain (AL) amyloidosis.
Academic Article Bortezomib and high-dose melphalan conditioning for stem cell transplantation for AL amyloidosis: a pilot study.
Academic Article Amyloidomics comes of age.
Academic Article Role of high-dose melphalan and autologous peripheral blood stem cell transplantation in AL amyloidosis.
Academic Article Consensus guidelines for the conduct and reporting of clinical trials in systemic light-chain amyloidosis.
Academic Article Multiple arterial and venous thromboembolic complications in AL amyloidosis and cardiac involvement: a case report and literature review.
Academic Article Amyloid deposits in the bone marrow of patients with immunoglobulin light chain amyloidosis do not impact stem cell mobilization or engraftment.
Academic Article AL amyloidosis: who, what, when, why, and where.
Academic Article Amyloidosis of the gastrointestinal tract: a 13-year, single-center, referral experience.
Academic Article Melphalan, lenalidomide and dexamethasone for the treatment of immunoglobulin light chain amyloidosis: results of a phase II trial.
Academic Article A solitary mediastinal mass due to localized AL amyloidosis: case report and review of the literature.
Academic Article High-dose melphalan and stem cell transplantation for patients with AL amyloidosis: trends in treatment-related mortality over the past 17 years at a single referral center.
Academic Article Microbiologically documented infections in patients undergoing high-dose melphalan and autologous stem cell transplantation for the treatment of light chain amyloidosis.
Academic Article Risk of second primary malignancy in patients with AL amyloidosis treated with lenalidomide.
Academic Article New hematologic response criteria predict survival in patients with immunoglobulin light chain amyloidosis treated with high-dose melphalan and autologous stem-cell transplantation.
Academic Article AL (Immunoglobulin Light-Chain) Amyloidosis
Academic Article The Amyloidoses
Academic Article Hospital admissions following outpatient administration of high-dose melphalan and autologous SCT for AL amyloidosis.
Academic Article Optimal dosing of high-dose melphalan prior to autologous hematopoietic stem cell transplantation in a patient with AL amyloidosis and a solitary kidney.
Academic Article Modified high-dose melphalan and autologous SCT for AL amyloidosis or high-risk myeloma: analysis of SWOG trial S0115.
Academic Article Update on treatment of light chain amyloidosis.
Academic Article Long-term follow-up from a phase 1/2 study of single-agent bortezomib in relapsed systemic AL amyloidosis.
Academic Article Lymphadenopathy as a manifestation of amyloidosis: a case series.
Academic Article Simultaneous presentation of kappa-restricted chronic lymphocytic leukemia and lambda light chain AL amyloidosis.
Academic Article Induction Therapy with Bortezomib Followed by Bortezomib-High Dose Melphalan and Stem Cell Transplantation for Light Chain Amyloidosis: Results of a Prospective Clinical Trial.
Academic Article Plerixafor-augmented peripheral blood stem cell mobilization in AL amyloidosis with cardiac involvement: a case series.
Academic Article High dose melphalan and autologous peripheral blood stem cell transplantation in AL amyloidosis.
Academic Article Vertebral compression fractures as the initial presentation of AL amyloidosis: case series and review of literature.
Academic Article Risk factors for venous thromboembolism in immunoglobulin light chain amyloidosis.
Academic Article Serum free light chain trends between orthotopic heart transplantation and auto-SCT in patients with AL amyloidosis.
Academic Article Safety and efficacy of high-dose melphalan and auto-SCT in patients with AL amyloidosis and cardiac involvement.
Academic Article Single agent lenalidomide three times a week induces hematologic responses in AL amyloidosis patients on dialysis.
Academic Article Rationale, application and clinical qualification for NT-proBNP as a surrogate end point in pivotal clinical trials in patients with AL amyloidosis.
Academic Article In memoriam David C. Seldin, MD, PhD.
Academic Article Validation of new renal staging system in AL amyloidosis treated with high dose melphalan and stem cell transplantation.
Academic Article Pomalidomide and dexamethasone in the treatment of AL amyloidosis: results of a phase 1 and 2 trial.
Academic Article David C Seldin, MD, PhD: scientist, clinician, teacher, gentleman, 1957-2015.
Academic Article The Effect of Bone Marrow Plasma Cell Burden on Survival in Patients with Light Chain Amyloidosis Undergoing High-Dose Melphalan and Autologous Stem Cell Transplantation.
Academic Article Bendamustine-Induced Nephrogenic Diabetes Insipidus in a Patient With AL Amyloidosis.
Academic Article Clinical presentation and treatment responses in IgM-related AL amyloidosis.
Academic Article Immunoglobulin heavy light chain test quantifies clonal disease in patients with AL amyloidosis and normal serum free light chain ratio.
Academic Article Effect of severe hypoalbuminemia on toxicity of high-dose melphalan and autologous stem cell transplantation in patients with AL amyloidosis.
Academic Article Penile ulcers complicating systemic AL amyloidosis: a case report.
Academic Article Nonoperative Management of Spontaneous Splenic Rupture in a Patient with Light-Chain Amyloidosis: A Case Report.
Academic Article Long-term outcome of patients with AL amyloidosis treated with high-dose melphalan and stem cell transplantation: 20-year experience.
Academic Article Longitudinal systolic strain, cardiac function improvement, and survival following treatment of light-chain (AL) cardiac amyloidosis.
Academic Article Depression and anxiety in patients with AL amyloidosis as assessed by the SF-36 questionnaire: experience in 1226 patients.
Academic Article A phase II trial of lenalidomide for patients with AL amyloidosis.
Academic Article Transbronchial biopsies safely diagnose amyloid lung disease.
Academic Article The six-minute walk test in patients with AL amyloidosis: a single centre case series.
Academic Article A phase 1/2 study of the oral proteasome inhibitor ixazomib in relapsed or refractory AL amyloidosis.
Academic Article Hematologic relapse in AL amyloidosis after high-dose melphalan and stem cell transplantation.
Academic Article High-Dose Melphalan and Stem Cell Transplantation in Patients on Dialysis Due to Immunoglobulin Light-Chain Amyloidosis and Monoclonal Immunoglobulin Deposition Disease.
Academic Article The incidence of atrial fibrillation among patients with AL amyloidosis undergoing high-dose melphalan and stem cell transplantation: experience at a single institution.
Academic Article A longitudinal evaluation of health-related quality of life in patients with AL amyloidosis: associations with health outcomes over time.
Academic Article Psychometric validation of the SF-36 Health Survey in light chain amyloidosis: results from community-based and clinic-based samples.
Academic Article Neuralgic amyotrophy following high-dose melphalan and autologous peripheral blood stem cell transplantation for AL amyloidosis.
Academic Article Treatment patterns and health care resource utilization among patients with relapsed/refractory systemic light chain amyloidosis.
Academic Article Monoclonal gammopathy of undetermined significance in systemic transthyretin amyloidosis (ATTR).
Academic Article Predictive value of the new renal response criteria in AL amyloidosis treated with high dose melphalan and stem cell transplantation.
Academic Article Once AL amyloidosis: not always AL amyloidosis.
Academic Article Echocardiography and Survival in Light Chain Cardiac Amyloidosis: Back to Basics.
Academic Article Evaluation of a new continuous mononuclear cell collection procedure in a single transplant center cohort enriched for AL amyloidosis patients.
Academic Article High-dose melphalan and stem cell transplantation in AL amyloidosis with elevated cardiac biomarkers.
Academic Article Modified High-Dose Melphalan and Autologous Stem Cell Transplantation for Immunoglobulin Light Chain Amyloidosis.
Academic Article Outcomes of patients with AL amyloidosis and low serum free light chain levels at diagnosis.
Academic Article A library of ATTR amyloidosis patient-specific induced pluripotent stem cells for disease modelling and in vitro testing of novel therapeutics.
Academic Article Improvements in Cardiac Biomarkers are Associated with Better Health-Related Quality of Life in Patients with Light Chain Amyloidosis
Academic Article ABNORMAL LEFT ATRIAL MECHANICS PREDICT INCIDENT ATRIAL FIBRILLATION IN AL CARDIAC AMYLOIDOSIS FOLLOWING AUTOLOGOUS STEM CELL TRANSPLANTATION
Academic Article NEOD001 DEMONSTRATES CARDIAC BIOMARKER RESPONSES IN PATIENTS WITH LIGHT CHAIN AMYLOIDOSIS: RESULTS FROM THE PHASE 1/2 STUDY
Academic Article NEOD001 Demonstrates Organ Biomarker Responses in Patients With Light Chain Amyloidosis and Persistent Organ Dysfunction: Results From a Phase 1/2 Study
Academic Article Organ Biomarker Responses in Patients With Light Chain Amyloidosis Treated With NEOD001 Are Independent of Previous Hematologic Response
Academic Article Echocardiographic identification of cardiac amyloidosis patients capable of undergoing intensive treatment with intravenous melphalan therapy
Academic Article A retrospective comparison of the impact of darbepoetin or epoetin usage on red cell transfusions transfusions in autologous stem cell transplantation (SCT) for light-chain related amyloidosis
Academic Article Cryotherapy (ice chips) is effective in preventing melphalan-induced oral mucositis (OM) in patients with AL amyloidosis
Academic Article A retrospective analysis of the impact of erythropoeitic growth factor utilization on transfusion requirements in patients with AL amyloidosis undergoing autologous SCT
Academic Article Skin reactions associated with oral Revlimid (lenalidomide) in al amyloidosis (ALA); Patient teaching encouraging prompt reporting, and clinical assessment
Academic Article Amyloid
Academic Article Amyloid
Academic Article Blood
Academic Article Treatment-Related Mortality in Patients with AL Amyloidosis Undergoing High-Dose Melphalan and Stem Cell Transplantation: Trend Over The Past 14 Years at a Single Institution
Academic Article Bortezomib And High Dose Melphalan Followed By Autologous Stem Cell Transplantation (B-HDM/SCT) For The Treatment Of Al Amyloidosis: Results Of A Feasibility Study
Academic Article REDUCTION IN VENTRICULAR WALL THICKNESS FOLLOWING HIGH-DOSE CHEMOTHERAPY AND STEM-CELL TRANSPLANTATION FOR AL CARDIAC AMYLOIDOSIS
Academic Article Amyloid
Academic Article Modified high-dose melphalan and autologous stem cell transplantation (mHDM/SCT) in the treatment of AL amyloidosis (AL) and/or high-risk myeloma (hM): Analysis of a Southwest Oncology Group trial
Academic Article Clinical Pathways and Standard Operating Procedures: Essential Tools for Outpatient Stem Cell Transplant Programs Treating Patients With AL Amyloidosis
Academic Article Blood
Academic Article A Multidisciplinary Team Approach for Diagnosis and Treatment of Patients with AL Amyloidosis
Academic Article NEOD001 Demonstrates Cardiac Responses in Patients with Light Chain Amyloidosis and Persistent Organ Dysfunction in a Phase 1/2 Study Expansion
Academic Article Amyloid and Amyloidosis
Academic Article Development and validation of a survival staging system incorporating BNP in patients with light chain amyloidosis.
Academic Article Systemic immunoglobulin light chain amyloidosis.
Academic Article Cardiac biomarkers and health-related quality of life in patients with light chain (AL) amyloidosis.
Academic Article Bortezomib ocular toxicities: Outcomes with ketotifen.
Academic Article Long-term outcome of kidney transplantation in AL amyloidosis.
Academic Article Induction Therapy with Bortezomib and Dexamethasone and Conditioning with High-Dose Melphalan and Bortezomib Followed by Autologous Stem Cell Transplantation for Immunoglobulin Light Chain Amyloidosis: Long-Term Follow-Up Analysis.
Academic Article Delay treatment of AL amyloidosis at relapse until symptomatic: devil is in the details.
Academic Article High-dose melphalan and autologous peripheral blood stem cell transplantation in patients with AL amyloidosis and cardiac defibrillators.
Academic Article Early Detection of Multiorgan Light-Chain Amyloidosis by Whole-Body 18F-Florbetapir PET/CT.
Academic Article Long term outcome of patients treated on clinical trials of immunomodulatory agents for the treatment of Immunoglobulin light chain (AL) amyloidosis: A pooled analysis.
Academic Article Orthotopic heart transplant rejection in association with immunomodulatory therapy for AL amyloidosis: A case series and review of the literature.
Academic Article Prevalence and prognostic value of D-dimer elevation in patients with AL amyloidosis.
Academic Article Comparison of Ultrasound Features of Major Salivary Glands in Sarcoidosis, Amyloidosis, and Sjögren''s Syndrome.
Academic Article A new era of amyloidosis: the trends at a major US referral centre.
Academic Article Updated analysis of phase 2 study of bendamustine and dexamethasone in patients with relapsed/refractory systemic light chain (AL) amyloidosis.
Academic Article Safety of autologous stem cell transplantation in patients with known Human T-cell Lymphotropic Viruses Type 1 and 2 infection: A case series of four patients.
Academic Article Establishment of brain natriuretic peptide - based criteria for evaluating cardiac response to treatment in light chain (AL) amyloidosis.
Academic Article The utility of repeat kidney biopsy in systemic immunoglobulin light chain amyloidosis.
Academic Article Treatment Options For Relapsed/refractory Systemic Light-Chain (AL) Amyloidosis: Current Perspectives.
Academic Article Systemic AL amyloidosis with an undetectable plasma cell dyscrasia: A zebra without stripes.
Academic Article Quantitative [18F]florbetapir PET/CT may identify lung involvement in patients with systemic AL amyloidosis.
Academic Article Safety, tolerability, and response rates of daratumumab in relapsed AL amyloidosis: results of a phase 2 study.
Grant Oncopeptides: An Open-Label, Phase 1/2 Study of Melflufen and Dexamethasone for Patients with AL…
Grant Phase 1 Study of Pomalidomide, Bortezomib, and Dexamethasone (PVD) as First-Line Treatment of AL …
Academic Article Bendamustine With Dexamethasone in Relapsed/Refractory Systemic Light-Chain Amyloidosis: Results of a Phase II Study.
Academic Article Assessment of minimal residual disease using multiparametric flow cytometry in patients with AL amyloidosis.
Academic Article Daratumumab plus CyBorD for patients with newly diagnosed AL amyloidosis: safety run-in results of ANDROMEDA.
Academic Article High-Dose Melphalan and Autologous Peripheral Blood Stem Cell Transplantation in AL Amyloidosis.
Academic Article Improved Quantification of Cardiac Amyloid Burden in Systemic Light Chain Amyloidosis: Redefining Early Disease?
Academic Article Challenges in the management of patients with systemic light chain (AL) amyloidosis during the COVID-19 pandemic.
Academic Article Presence of t(11;14) in AL amyloidosis as a marker of response when treated with a bortezomib-based regimen.
Academic Article Patient outcomes in light chain (AL) amyloidosis: The clock is ticking from symptoms to diagnosis.
Academic Article AL Amyloidosis in Myeloma: Red Flag Symptoms.
Academic Article Organ responses after highdose melphalan and stemcell transplantation in AL amyloidosis.
Academic Article Comparing measures of hematologic response after high-dose melphalan and stem cell transplantation in AL amyloidosis.
Academic Article A pharmacist''s review of the treatment of systemic light chain amyloidosis.
Grant An Open-Label, Dose-Escalation, Phase 1 Study of the Oral Formulation of MLN9708 Administered Weekly in Adult Patients with Relapsed or Refractory Light-Chain (AL) Amyloidosis Who Require Further
Grant Phase II trial of induction therapy with Bortezomib and Dexamethasone followed by high-dose melphalan and stem cell transplantation in patients with AL amyloidosis
Grant A Phase I/II Trial of Pomalidomide and Dexamethasone for the treatment of patients with AL Amyloidosis
Grant An Open Label, Phase 1/2 Study of Velcade (bortezomib) for Injection in Subjects with Light Chain Amyloidosis
Grant A MulticenterPhase II Trial of Velcade, Melphalan, and Dexamethasone (V-MD) in Patients with AL Amyloidosis or LCDD
Grant A Phase I Dose-Escalation Study of Carflizomib in Patients with Previously-Treated Systemic Light-Chain (AL) Amyloidosis
Grant Phase II study of the combination Bendamustine and Dexamethasone in patients with relapsed AL amyloidosis
Grant A phase 1, open label, dose escalation study of intravenous administration of single agent NEOD001 in subjects with light chain (AL) amyloidosis
Academic Article Systemic Amyloidosis Caused by Monoclonal Immunoglobulins: Soft Tissue and Vascular Involvement.

Highlights
Search Criteria
  • AL
  • amyloidosis