Search Results to John L. Berk, MD

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One or more keywords matched the following properties of Berk, John

Research Expertise & Professional Interests Expertise in Amyloidosis with specific emphasis in Familial and localized amyloid disease; pulmonary fibrosis.
Self-Described Keywords amyloid lung disease

One or more keywords matched the following items that are connected to Berk, John

Item TypeName
Concept Amyloid
Concept Autoimmune Diseases
Concept Autonomic Nervous System Diseases
Concept Bronchial Diseases
Concept Conjunctival Diseases
Concept Gastrointestinal Diseases
Concept Heart Diseases
Concept Kidney Diseases
Concept Laryngeal Diseases
Concept Lung Diseases
Concept Lymphatic Diseases
Concept Protein-Lysine 6-Oxidase
Concept Mediastinal Diseases
Concept Nervous System Diseases
Concept Parkinson Disease
Concept Protein Processing, Post-Translational
Concept Protein Synthesis Inhibitors
Concept Proteinuria
Concept Recombinant Proteins
Concept Tracheal Diseases
Concept Protein Biosynthesis
Concept Protein Structure, Secondary
Concept Protein Folding
Concept Lung Diseases, Interstitial
Concept Amyloid Neuropathies
Concept Disease Progression
Concept Disease-Free Survival
Concept Genetic Predisposition to Disease
Concept Amyloid Neuropathies, Familial
Concept Retinol-Binding Proteins, Plasma
Concept Protein Multimerization
Concept Protein Stability
Concept Asymptomatic Diseases
Concept Protein Unfolding
Academic Article The effect of retinoic acid on amino acid uptake and protein synthesis by lung fibroblasts.
Academic Article Regulation of type I collagen production by insulin and transforming growth factor-beta in human lung fibroblasts.
Academic Article Intermediate-dose intravenous melphalan and blood stem cells mobilized with sequential GM+G-CSF or G-CSF alone to treat AL (amyloid light chain) amyloidosis.
Academic Article Dose-intensive melphalan with blood stem-cell support for the treatment of AL (amyloid light-chain) amyloidosis: survival and responses in 25 patients.
Academic Article Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 20-1998. A 53-year-old man with cardiac amyloidosis and a left pulmonary mass.
Academic Article Hypoxia downregulates tropoelastin gene expression in rat lung fibroblasts by pretranslational mechanisms.
Academic Article Effect of dose-intensive intravenous melphalan and autologous blood stem-cell transplantation on al amyloidosis-associated renal disease.
Academic Article Tracheobronchial amyloidosis. The Boston University experience from 1984 to 1999.
Academic Article Low-dose continuous oral melphalan for the treatment of primary systemic (AL) amyloidosis.
Academic Article Tolerability and efficacy of thalidomide for the treatment of patients with light chain-associated (AL) amyloidosis.
Academic Article High-dose intravenous melphalan and autologous stem cell transplantation as initial therapy or following two cycles of oral chemotherapy for the treatment of AL amyloidosis: results of a prospective randomized trial.
Academic Article Pleural effusions in systemic amyloidosis.
Academic Article Diaphragm paralysis in primary systemic amyloidosis.
Academic Article Quantitative serum free light chain assay in the diagnostic evaluation of AL amyloidosis.
Academic Article Recombinant interleukin-1 beta inhibits elastin formation by a neonatal rat lung fibroblast subtype.
Academic Article Oral cyclic melphalan and dexamethasone for patients with AL amyloidosis.
Academic Article Macroglossia - not always AL amyloidosis.
Academic Article Amyloidotic cardiomyopathy: multidisciplinary approach to diagnosis and treatment.
Academic Article Outcome of AL amyloidosis after high-dose melphalan and autologous stem cell transplantation: long-term results in a series of 421 patients.
Academic Article High-dose melphalan and autologous stem cell transplantation for AL amyloidosis: recent trends in treatment-related mortality and 1-year survival at a single institution.
Academic Article Regression of cardiac wall thickness following chemotherapy and stem cell transplantation for light chain (AL) amyloidosis.
Academic Article The diflunisal trial: update on study drug tolerance and disease progression.
Academic Article The Diflunisal Trial: study accrual and drug tolerance.
Academic Article Long-term results of conformal radiotherapy for progressive airway amyloidosis.
Academic Article Amyloidosis of the gastrointestinal tract: a 13-year, single-center, referral experience.
Academic Article Guideline of transthyretin-related hereditary amyloidosis for clinicians.
Academic Article A solitary mediastinal mass due to localized AL amyloidosis: case report and review of the literature.
Academic Article Regulation of lysyl oxidase expression in lung fibroblasts by transforming growth factor-beta 1 and prostaglandin E2.
Academic Article Neuronal molecular mimicry in immune-mediated neurologic disease.
Academic Article Efficacy and safety of patisiran for familial amyloidotic polyneuropathy: a phase II multi-dose study.
Academic Article Lymphadenopathy as a manifestation of amyloidosis: a case series.
Academic Article Discordant phenotype in monozygotic female twins with Lys35Thr TTR familial amyloidotic polyneuropathy.
Academic Article Cooperative stabilization of transthyretin by clusterin and diflunisal.
Academic Article Repurposing diflunisal for familial amyloid polyneuropathy: a randomized clinical trial.
Academic Article Safety and efficacy of high-dose melphalan and auto-SCT in patients with AL amyloidosis and cardiac involvement.
Academic Article Retrospective study of a TTR FAP cohort to modify NIS+7 for therapeutic trials.
Academic Article Heart Failure Resulting From Age-Related Cardiac Amyloid Disease Associated With Wild-Type Transthyretin: A Prospective, Observational Cohort Study.
Academic Article Clinical presentation and treatment responses in IgM-related AL amyloidosis.
Academic Article Assessing mNIS+7Ionis and international neurologists'' proficiency in a familial amyloidotic polyneuropathy trial.
Academic Article Nonbiopsy Diagnosis of Cardiac Transthyretin Amyloidosis.
Academic Article Can 99mTc-Pyrophosphate Aid in Early Detection of Cardiac Involvement in Asymptomatic Variant TTR Amyloidosis?
Academic Article Depression and anxiety in patients with AL amyloidosis as assessed by the SF-36 questionnaire: experience in 1226 patients.
Academic Article Retinol binding protein 4 (RBP4) concentration identifies V122I transthyretin cardiac amyloidosis.
Academic Article Identification of Transthyretin Cardiac Amyloidosis Using Serum Retinol-Binding Protein 4 and a Clinical Prediction Model.
Academic Article Transbronchial biopsies safely diagnose amyloid lung disease.
Academic Article Familial wild-type transthyretin cardiomyopathy.
Academic Article Artificial neural network modelling of ATTR amyloidosis: is now the time?
Academic Article Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients.
Academic Article Prevalence of mutant ATTR cardiac amyloidosis in elderly African Americans with heart failure.
Academic Article Monoclonal gammopathy of undetermined significance in systemic transthyretin amyloidosis (ATTR).
Academic Article Use of Serum Transthyretin as a Prognostic Indicator and Predictor of Outcome in Cardiac Amyloid Disease Associated With Wild-Type Transthyretin.
Academic Article Once AL amyloidosis: not always AL amyloidosis.
Academic Article External beam radiation for localized periocular amyloidosis: a case series.
Academic Article Features of atrial fibrillation in wild-type transthyretin cardiac amyloidosis: a systematic review and clinical experience.
Academic Article Unusual duplication mutation in a surface loop of human transthyretin leads to an aggressive drug-resistant amyloid disease.
Academic Article Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis.
Academic Article Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis.
Academic Article A library of ATTR amyloidosis patient-specific induced pluripotent stem cells for disease modelling and in vitro testing of novel therapeutics.
Academic Article Hereditary transthyretin amyloidosis: baseline characteristics of patients in the NEURO-TTR trial.
Academic Article Oligonucleotide Drugs for Transthyretin Amyloidosis.
Academic Article Effects of Patisiran, an RNA Interference Therapeutic, on Cardiac Parameters in Patients With Hereditary Transthyretin-Mediated Amyloidosis.
Academic Article TTR Gene Silencers for Hereditary ATTR Amyloidosis: More than ICER Recognized.
Academic Article Neuropathy Associated with Systemic Amyloidosis.
Academic Article Analysis of autonomic outcomes in APOLLO, a phase III trial of the RNAi therapeutic patisiran in patients with hereditary transthyretin-mediated amyloidosis.
Academic Article Quality of life outcomes in APOLLO, the phase 3 trial of the RNAi therapeutic patisiran in patients with hereditary transthyretin-mediated amyloidosis.
Academic Article TTR gene silencing therapy in post liver transplant hereditary ATTR amyloidosis patients.
Grant An Open-Label Extension Study to Assess the Long-Term Safety and Efficacy of ISIS 420915 in Patients with Familial Amyloid Polyneuropathy
Grant A study of the Natural History of Leukocyte Chemotactic Factor 2 Amyloidosis (ALECT2) Disease
Grant Protocol # ION-682844-CS3: A Phase 3 Global, Open-Label, Randomized Study to Evaluate the Efficacy and Safety of ION-682884 in Patients with Hereditary Transthyretin-Mediated Amyloid Polyneuropathy
Grant A phase 2/3 randomized, double-blind, placebo controlled study to assess the efficacy and safety of Isis 420915 In Patients with Amyloid Polyneuropathy
Grant Protocol ION-682884-CS2: A Phase 3 Global, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of ION-682884 in Patients with Transthyretin-Mediated Amyloid Cardiomy
Grant A Randomised, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of GSK2998728 in Subjects with Transthyretin Amyloid Cardiomyopathy, FAC204650
Grant A phase 2, open-label, multi-dose, dose escalation trial to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of intravenous infusions of ALN-TTR02 in patients with TTR Amyloid
Grant "A Phase 3, Randomized, Double-Blind, Placebo-controlled Study of the Efficacy and Safety of AG10 in Subjects with Symptomatic Transthyretin Amyloid Cardiomyopathy"

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  • Protein
  • misfolding
  • amyloid
  • diseases