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Research Expertise & Professional Interests Gheorghe Doros is Professor of Biostatistics and director of the Biostatistics Consulting Group. He received his PhD in Statistics from Yale University and joined BUSPH’s Department of Biostatistics in 2006 after spending two years at Eli Lilly, as a member of that company's Drug Discovery and Toxicology department. Dr. Doros’s research on methodological approaches and strategies has been concentrated in the area of clinical trials, more specifically on Bayesian approaches to clinical trials and the area of placebo response in clinical trials. The outcome of his work has been a corner stone in developing a host of collaborations with outstanding faculty, clinicians, and researchers at the Boston University Medical Campus and at other institutions. These productive collaborations have resulted in several federally funded grants. Dr. Doros authored and co-authored many peer-reviewed publications of original and innovative research which has had a major impact on the field. On the majority of publications, Dr. Doros is the lead statistician author. He demonstrated continuing record of multidisciplinary research that has had a major impact on the rapidly changing field. His publications on clinical trials; most proposing the design, analysis and new methodologies or of significant contributions to this field. Dr. Doros is a very active and effective teacher and mentor in the department of Biostatistics. His teaching philosophy is to pursue an active approach to learning and to engage students to think critically. He taught core and elective courses for Master and PhD-level courses. The excellent course evaluations he received attests to his ability in engaging students in active learning. Dr. Doros has been awarded the excellence in teaching three times in three years. On a national level, Dr. Doros has served as an Associate Editor for the BioMed Central’s journal Trials and as a reviewer for a number of academic journals. He served as a member of the merit review subcommittee for Epidemiology of the Department of Veteran Affairs and a member NHLBI-Ancillary Studies in Clinical Trials between 2012 and 2014. He has served as a statistical expert on a number of Independent Data Monitoring Committee(IDMC) for clinical trials and clinical programs. He served or seves as a senior consultant on multicenter trials and/or programs for the following organizations Pfizer, Takeda, Avanir, Sarepta and Children's Hospital.

One or more keywords matched the following items that are connected to Doros, Gheorghe

Item TypeName
Concept Clinical Decision-Making
Concept Clinical Clerkship
Concept Clinical Competence
Concept Clinical Protocols
Concept Clinical Trials as Topic
Concept Research Design
Concept Research Support as Topic
Concept Clinical Trials, Phase I as Topic
Concept Clinical Trials, Phase II as Topic
Concept Clinical Trials, Phase III as Topic
Concept Comparative Effectiveness Research
Academic Article Recent treatment history vs clinical characteristics in the prediction of use of outpatient psychiatric services.
Academic Article Probability of replication revisited: comment on "An alternative to Null-Hypothesis Significance Tests.".
Academic Article Clinical effects of erdosteine in the treatment of acute respiratory tract diseases in children.
Academic Article Soft tissue, joint, and bone manifestations of AL amyloidosis: clinical presentation, molecular features, and survival.
Academic Article The Boston bowel preparation scale: a valid and reliable instrument for colonoscopy-oriented research.
Academic Article Cardiac amyloidosis in African Americans: comparison of clinical and laboratory features of transthyretin V122I amyloidosis and immunoglobulin light chain amyloidosis.
Academic Article Diagnosis and measurement of subjective incompetence: the clinical hallmark of demoralization.
Academic Article Poractant alfa and beractant treatment of very premature infants with respiratory distress syndrome.
Academic Article A third-year surgery clerkship with extensive exposure to vascular surgery improves knowledge about vascular disease and the role of vascular surgeons in its management.
Academic Article A point-of-care clinical trial comparing insulin administered using a sliding scale versus a weight-based regimen.
Academic Article Clinical features and survival in senile systemic amyloidosis: comparison to familial transthyretin cardiomyopathy.
Academic Article A repeated measures model for analysis of continuous outcomes in sequential parallel comparison design studies.
Academic Article Using vascular quality initiative as a platform for organizing multicenter, prospective, randomized clinical trials: OVERPAR trial.
Academic Article Perspectives on endovascular training in traditional 5+2 vascular surgery fellowship training programs.
Academic Article Nonparametric Prediction of Event Times for Analysis of Failure-Time Data.
Academic Article Placebo non-response measure in sequential parallel comparison design studies.
Academic Article Efficacy of electrical stimulation and exercise for dysphagia in patients with head and neck cancer: A randomized clinical trial.
Academic Article Variability in freedom from loss of primary patency results in trials assessing stent implantation in the superficial femoral artery.
Academic Article Testosterone therapy in men with Crohn''s disease improves the clinical course of the disease: data from long-term observational registry study.
Academic Article Impact of Compliance on Dysphagia Rehabilitation in Head and Neck Cancer Patients: Results from a Multi-center Clinical Trial.
Academic Article Statistical considerations for stopping systemic lupus erythematosus clinical trials earlier.
Academic Article Preoperative Hypoalbuminemia Is Associated With Poor Clinical Outcomes After Open and Endovascular Abdominal Aortic Aneurysm Repair.
Academic Article Anticholinergic vs Long-Acting ß-Agonist in Combination With Inhaled Corticosteroids in Black Adults With Asthma: The BELT Randomized Clinical Trial.
Academic Article Effect of team training on improving MRI study completion rates and no-show rates.
Academic Article Testosterone therapy in hypogonadal men results in sustained and clinically meaningful weight loss.
Academic Article Preoperative hypoalbuminemia is associated with poor clinical outcomes after open and endovascular abdominal aortic aneurysm repair.
Academic Article Design and implementation of electronic health record integrated clinical prediction rules (iCPR): a randomized trial in diverse primary care settings.
Academic Article The association of Carotid Revascularization Endarterectomy versus Stent Trial (CREST) and Centers for Medicare and Medicaid Services Carotid Guideline Publication on utilization and outcomes of carotid stenting among "high-risk" patients.
Academic Article Contemporary Trends in Oral Anticoagulant Prescription in Atrial Fibrillation Patients at Low to Moderate Risk of Stroke After Guideline-Recommended Change in Use of the CHADS2 to the CHA2DS2-VASc Score for Thromboembolic Risk Assessment: Analysis From the National Cardiovascular Data Registry''s Outpatient Practice Innovation and Clinical Excellence Atrial Fibrillation Registry.
Academic Article Factors associated with rhythm control treatment decisions in patients with atrial fibrillation-Insights from the NCDR PINNACLE registry.
Academic Article External validation of Vascular Study Group of New England risk predictive model of mortality after elective abdominal aorta aneurysm repair in the Vascular Quality Initiative and comparison against established models.
Academic Article Perioperative outcomes after reoperative carotid endarterectomy are worse than expected.
Academic Article A single center analysis of factors influencing study start-up timeline in clinical trials.
Academic Article Comparison of access type on perioperative outcomes after endovascular aortic aneurysm repair.
Academic Article Addition or removal of guideline directed medical therapy in ambulatory patients with heart failure with reduced ejection fraction relative to change in symptom severity: An analysis from the PINNACLE (Practice Innovation and Clinical Excellence) Registry®.
Academic Article Routine Use of Ultrasound Guidance in Femoral Arterial Access for Peripheral Vascular Intervention Decreases Groin Hematoma Rates in High-Volume Surgeons.
Academic Article Safety and efficacy of dual vs. triple antithrombotic therapy in patients with atrial fibrillation following percutaneous coronary intervention: a systematic review and meta-analysis of randomized clinical trials.
Academic Article Retraction notice to Addition or removal of guideline directed medical therapy in ambulatory patients with heart failure with reduced ejection fraction relative to change in symptom severity: An analysis from the PINNACLE (Practice Innovation and Clinical Excellence) Registry® [International Journal of Cardiology 254 (2018) 222-223].
Academic Article Features of atrial fibrillation in wild-type transthyretin cardiac amyloidosis: a systematic review and clinical experience.
Academic Article Clinical Variables Associated with Wound Complication after Open Femoral Exposure for Endovascular Abdominal Aortic Aneurysm Repair
Academic Article Patients with Heart Failure with Mid-Range Ejection Fraction Have a Distinct Clinical Profile: An Analysis from the PINNACLE (Practice Innovation and Clinical Excellence) Registry
Academic Article PS96. Routine Compared to Selective Use of Completion Imaging after Infrainguinal Lower Extremity Bypass Is Not Associated with Higher Bypass Graft Patency
Academic Article Do 5a-Reductase Inhibitors Raise Circulating Serum Testosterone Levels? A Comprehensive Review and Meta-Analysis to Explaining Paradoxical Results.
Academic Article Long term outcome of patients treated on clinical trials of immunomodulatory agents for the treatment of Immunoglobulin light chain (AL) amyloidosis: A pooled analysis.
Academic Article Comparison of novel methods in two-way enriched clinical trial design.
Academic Article Comparison of Early and Late Post-operative Outcomes after Supra-inguinal Bypass for Aortoiliac Occlusive Disease.
Grant Personnel Agreement for Research Services of Gheorghe Doros
Grant Gheorghe Doros, PhD: Statistical research in clinical trials (Baim Institute for Clinical Research)
Grant Personnel Agreement for Research Services of Gheorghe Doros
Grant Personnel Agreement for Research Services of Gheorghe Doros
Grant Personnel Agreement for Research Services of Gheorghe Doros
Grant Gheorghe Doros, PhD (faculty): Statistical research in clinical trials (Harvard Clinical Research Institute)
Grant Personnel agreement for research services of Gheorghe Doros

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