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One or more keywords matched the following properties of Ramachandran, Vasan

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Research Expertise & Professional Interests Vasan S. Ramachandran, M.D., Principal Investigator and Director of the FHS, and Director of the FHS fellowship program in cardiovascular epidemiology for the last 25 years. Dr. Ramachandran is a Professor of Medicine and Epidemiology at BUSM/BUSPH, and Chief, Section of Preventive Medicine and Epidemiology, Department of Medicine, BUSM. He is the Jay & Louis Coffman Professor of Vascular Medicine at BUSM. Dr. Ramachandran is a trained cardiologist with subspecialty training in echocardiography. He is a fellow of the AHA Councils on Epidemiology and Prevention and Functional Genomics and Translational Biology, and a fellow of the American College of Cardiology (ACC). He has extensive experience in supervising trainees at many levels and has taught the foundational core course on Cardiovascular Epidemiology at BUSPH (EP751). He has several active R01 grants from the NHLBI/NIDDK and received two K24 Mid-Career Investigator mentoring grants from the NHLBI. He has mentored several K23 awardees, and is currently the Principal Investigator of a post-doctoral training program (T32) in cardiovascular epidemiology. Overall, he has supervised over 70 trainees during the past 20 years; most are in key positions in academia. He received the Outstanding Mentor awards from the Department of Medicine, BUSM, and the AHA Council on Epidemiology and Prevention, and the prestigious AHA Population Science Award in 2014. Importantly, Dr. Ramachandran’s own peer-reviewed funding spans thematic areas of genetics and genomics, cardiac and vascular remodeling, novel biomarkers, systems biology including proteomics and metabolomics, and stem cell biology. He has a 25-year history in research in cardiovascular epidemiology, including the two years he trained as a FHS fellow (1993-1995). He established the first School of Public Health in India between 1996-1998, serving as its inaugural director and the coordinator of its MPH program. He is the founding member and leader of the international EchoGen consortium, and chairs the Steering Committee of the Chronic Kidney Disease Biomarker Consortium funded by the NIDDK (U01DK085689). He is recognized internationally for translational research in cardiovascular epidemiology and lectures regularly at the AHA early career session on “how to develop a career in translational research and epidemiology/genetics.” He is well equipped to mentor trainees about grant writing having been a member of the Cardiovascular and Sleep (CASE) SRG, and an active reviewer of grants for national and international funding agencies. He served for many years on the NHLBI panel for reviewing K23-K24-K25 career development grants. He is well qualified to mentor trainees in best publication practices and has served until recently as an Associate Editor for Circulation, and the Editor-in-Chief of Circulation: Cardiovascular Genetics. He works directs the Center for Integrative Transdisciplinary Epidemiology within BUSM, that hosts multiple epidemiological datasets, including from multiple cohort studies, national surveys (NHANES), administrative databases and electronic health records; this center will be a valuable data source for trainees. For the last 20 years, Dr. Ramachandran has focused his research on A) the genetic and non-genetic epidemiology of congestive heart failure, including identifying risk factors for the disease, characterizing the subgroups with diastolic heart failure, asymptomatic LV systolic and diastolic dysfunction, and evaluating the role of LV remodeling; B) population-based vascular testing and echocardiography, including identifying biological, environmental, and genetic determinants (correlates) of cardiac structure and function; normative standards; detailed assessment of biomarkers of the process of LV remodeling, including but not limited to role of natriuretic peptides, insulin resistance, cardiac extracellular matrix markers, oxidative stress, inflammation, growth factors; genetics of LV remodeling, LA and aortic structure and gene-environment interactions; brachial artery endothelial function, its correlates and tonometric assessment of large artery function; C) genetic and non-genetic epidemiology of high blood pressure, including characterizing the lifetime risk, rates of progression and risks associated with various degrees of elevation; large artery stiffness and function and role in systolic hypertension in the elderly; genetics of high blood pressure and large artery function; and D) CVD risk estimation in the short, medium- and long-term, with novel biomarkers including genomic biomarkers.

One or more keywords matched the following items that are connected to Ramachandran, Vasan

Item TypeName
Concept Fibroblast Growth Factors
Concept Insulin-Like Growth Factor I
Concept Growth Hormone
Concept Hepatocyte Growth Factor
Concept Insulin-Like Growth Factor Binding Proteins
Concept Insulin-Like Growth Factor Binding Protein 3
Concept Human Growth Hormone
Concept Receptors, Vascular Endothelial Growth Factor
Concept Vascular Endothelial Growth Factor Receptor-1
Concept Vascular Endothelial Growth Factor Receptor-2
Concept Vascular Endothelial Growth Factors
Concept Vascular Endothelial Growth Factor A
Concept Vascular Endothelial Growth Factor C
Concept Growth Differentiation Factor 15
Academic Article Absence of association or genetic linkage between the angiotensin-converting-enzyme gene and left ventricular mass.
Academic Article Serum insulin-like growth factor I and risk for heart failure in elderly individuals without a previous myocardial infarction: the Framingham Heart Study.
Academic Article Clinical and genetic factors associated with lipoprotein-associated phospholipase A2 in the Framingham Heart Study.
Academic Article Vascular endothelial growth factor, its soluble receptor, and hepatocyte growth factor: clinical and genetic correlates and association with vascular function.
Academic Article A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3.
Academic Article Circulating insulin-like growth factor-1 and its binding protein-3: metabolic and genetic correlates in the community.
Academic Article Circulating angiogenic cell populations, vascular function, and arterial stiffness.
Academic Article Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels.
Academic Article Relation of vascular growth factors with CT-derived measures of body fat distribution: the Framingham Heart Study.
Academic Article Circulating vascular growth factors and central hemodynamic load in the community.
Academic Article Prognostic utility of novel biomarkers of cardiovascular stress: the Framingham Heart Study.
Academic Article Clinical and genetic correlates of growth differentiation factor 15 in the community.
Academic Article Biomarkers of cardiovascular stress and incident chronic kidney disease.
Academic Article Serum brain-derived neurotrophic factor and vascular endothelial growth factor levels are associated with risk of stroke and vascular brain injury: Framingham Study.
Academic Article Association of novel biomarkers of cardiovascular stress with left ventricular hypertrophy and dysfunction: implications for screening.
Academic Article Relation between soluble ST2, growth differentiation factor-15, and high-sensitivity troponin I and incident atrial fibrillation.
Academic Article Genome-wide association and functional studies identify a role for IGFBP3 in hip osteoarthritis.
Academic Article Biomarkers of cardiovascular stress and subclinical atherosclerosis in the community.
Academic Article Genome-wide association study for endothelial growth factors.
Academic Article Associations of Circulating Growth Differentiation Factor-15 and ST2 Concentrations With Subclinical Vascular Brain Injury and Incident Stroke.
Academic Article A robust method for genome-wide association meta-analysis with the application to circulating insulin-like growth factor I concentrations.
Academic Article Serum fibroblast growth factor-23 is associated with incident kidney disease.
Academic Article Cardiovascular endocrinology: Growth hormone in CVD prediction--a tall order?
Academic Article Insulin-like growth factor-1 and risk of Alzheimer dementia and brain atrophy.
Academic Article Circulating vascular endothelial growth factor and the risk of cardiovascular events.
Academic Article Plasma Fibroblast Growth Factor 23: Clinical Correlates and Association With Cardiovascular Disease and Mortality in the Framingham Heart Study.
Academic Article Relations of circulating GDF-15, soluble ST2, and troponin-I concentrations with vascular function in the community: The Framingham Heart Study.
Academic Article Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits.
Academic Article Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies.
Academic Article Association of the IGF1 gene with fasting insulin levels.
Academic Article Circulating biomarkers and incident ischemic stroke in the Framingham Offspring Study.
Academic Article Associations of objective physical activity with insulin sensitivity and circulating adipokine profile: the Framingham Heart Study.
Academic Article Serum Insulin-Like Growth Factor 1 and the Risk of Ischemic Stroke: The Framingham Study.

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