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Search Results to Vasan S. Ramachandran, MD

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Research Expertise & Professional Interests Vasan S. Ramachandran, M.D., Principal Investigator and Director of the FHS, and Director of the FHS fellowship program in cardiovascular epidemiology for the last 25 years. Dr. Ramachandran is a Professor of Medicine and Epidemiology at BUSM/BUSPH, and Chief, Section of Preventive Medicine and Epidemiology, Department of Medicine, BUSM. He is the Jay & Louis Coffman Professor of Vascular Medicine at BUSM. Dr. Ramachandran is a trained cardiologist with subspecialty training in echocardiography. He is a fellow of the AHA Councils on Epidemiology and Prevention and Functional Genomics and Translational Biology, and a fellow of the American College of Cardiology (ACC). He has extensive experience in supervising trainees at many levels and has taught the foundational core course on Cardiovascular Epidemiology at BUSPH (EP751). He has several active R01 grants from the NHLBI/NIDDK and received two K24 Mid-Career Investigator mentoring grants from the NHLBI. He has mentored several K23 awardees, and is currently the Principal Investigator of a post-doctoral training program (T32) in cardiovascular epidemiology. Overall, he has supervised over 70 trainees during the past 20 years; most are in key positions in academia. He received the Outstanding Mentor awards from the Department of Medicine, BUSM, and the AHA Council on Epidemiology and Prevention, and the prestigious AHA Population Science Award in 2014. Importantly, Dr. Ramachandran’s own peer-reviewed funding spans thematic areas of genetics and genomics, cardiac and vascular remodeling, novel biomarkers, systems biology including proteomics and metabolomics, and stem cell biology. He has a 25-year history in research in cardiovascular epidemiology, including the two years he trained as a FHS fellow (1993-1995). He established the first School of Public Health in India between 1996-1998, serving as its inaugural director and the coordinator of its MPH program. He is the founding member and leader of the international EchoGen consortium, and chairs the Steering Committee of the Chronic Kidney Disease Biomarker Consortium funded by the NIDDK (U01DK085689). He is recognized internationally for translational research in cardiovascular epidemiology and lectures regularly at the AHA early career session on “how to develop a career in translational research and epidemiology/genetics.” He is well equipped to mentor trainees about grant writing having been a member of the Cardiovascular and Sleep (CASE) SRG, and an active reviewer of grants for national and international funding agencies. He served for many years on the NHLBI panel for reviewing K23-K24-K25 career development grants. He is well qualified to mentor trainees in best publication practices and has served until recently as an Associate Editor for Circulation, and the Editor-in-Chief of Circulation: Cardiovascular Genetics. He works directs the Center for Integrative Transdisciplinary Epidemiology within BUSM, that hosts multiple epidemiological datasets, including from multiple cohort studies, national surveys (NHANES), administrative databases and electronic health records; this center will be a valuable data source for trainees. For the last 20 years, Dr. Ramachandran has focused his research on A) the genetic and non-genetic epidemiology of congestive heart failure, including identifying risk factors for the disease, characterizing the subgroups with diastolic heart failure, asymptomatic LV systolic and diastolic dysfunction, and evaluating the role of LV remodeling; B) population-based vascular testing and echocardiography, including identifying biological, environmental, and genetic determinants (correlates) of cardiac structure and function; normative standards; detailed assessment of biomarkers of the process of LV remodeling, including but not limited to role of natriuretic peptides, insulin resistance, cardiac extracellular matrix markers, oxidative stress, inflammation, growth factors; genetics of LV remodeling, LA and aortic structure and gene-environment interactions; brachial artery endothelial function, its correlates and tonometric assessment of large artery function; C) genetic and non-genetic epidemiology of high blood pressure, including characterizing the lifetime risk, rates of progression and risks associated with various degrees of elevation; large artery stiffness and function and role in systolic hypertension in the elderly; genetics of high blood pressure and large artery function; and D) CVD risk estimation in the short, medium- and long-term, with novel biomarkers including genomic biomarkers.

One or more keywords matched the following items that are connected to Ramachandran, Vasan

Item TypeName
Concept Cognition Disorders
Concept Endothelium, Vascular
Concept Vascular Diseases
Concept Vascular Resistance
Concept Peripheral Vascular Diseases
Concept Receptors, Vascular Endothelial Growth Factor
Concept Vascular Endothelial Growth Factor Receptor-1
Concept Vascular Endothelial Growth Factor Receptor-2
Concept Vascular Endothelial Growth Factors
Concept Vascular Endothelial Growth Factor A
Concept Vascular Endothelial Growth Factor C
Concept Vascular Stiffness
Concept Vascular Calcification
Concept Vascular Remodeling
Academic Article Clinical correlates and heritability of flow-mediated dilation in the community: the Framingham Heart Study.
Academic Article Local shear stress and brachial artery flow-mediated dilation: the Framingham Heart Study.
Academic Article Predictors of new-onset diastolic and systolic hypertension: the Framingham Heart Study.
Academic Article Low-grade albuminuria and the risks of hypertension and blood pressure progression.
Academic Article Brachial artery vasodilator function and systemic inflammation in the Framingham Offspring Study.
Academic Article Heritability and a genome-wide linkage scan for arterial stiffness, wave reflection, and mean arterial pressure: the Framingham Heart Study.
Academic Article Genome scan of systemic biomarkers of vascular inflammation in the Framingham Heart Study: evidence for susceptibility loci on 1q.
Academic Article Cross-sectional relations of peripheral microvascular function, cardiovascular disease risk factors, and aortic stiffness: the Framingham Heart Study.
Academic Article Cross-sectional relations of multiple biomarkers from distinct biological pathways to brachial artery endothelial function.
Academic Article Left ventricular mass, blood pressure, and lowered cognitive performance in the Framingham offspring.
Academic Article Relation of obesity to cognitive function: importance of central obesity and synergistic influence of concomitant hypertension. The Framingham Heart Study.
Academic Article Vascular stiffness and genetic variation at the endothelial nitric oxide synthase locus: the Framingham Heart study.
Academic Article Pericardial fat, visceral abdominal fat, cardiovascular disease risk factors, and vascular calcification in a community-based sample: the Framingham Heart Study.
Academic Article BMI vs. waist circumference for identifying vascular risk.
Academic Article Relation of season and temperature to endothelium-dependent flow-mediated vasodilation in subjects without clinical evidence of cardiovascular disease (from the Framingham Heart Study).
Academic Article Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study.
Academic Article Cross-sectional relations of digital vascular function to cardiovascular risk factors in the Framingham Heart Study.
Academic Article Relations of measures of endothelial function and kidney disease: the Framingham Heart Study.
Academic Article Clinical and genetic factors associated with lipoprotein-associated phospholipase A2 in the Framingham Heart Study.
Academic Article Carotid artery atherosclerosis, MRI indices of brain ischemia, aging, and cognitive impairment: the Framingham study.
Academic Article Visceral and subcutaneous adiposity and brachial artery vasodilator function.
Academic Article Cross-sectional relations of multiple inflammatory biomarkers to peripheral arterial disease: The Framingham Offspring Study.
Academic Article Multimarker approach to evaluate correlates of vascular stiffness: the Framingham Heart Study.
Academic Article Association between arterial stiffness and variations in oestrogen-related genes.
Academic Article Vascular endothelial growth factor, its soluble receptor, and hepatocyte growth factor: clinical and genetic correlates and association with vascular function.
Academic Article Triglycerides as vascular risk factors: new epidemiologic insights.
Academic Article Major lipids, apolipoproteins, and risk of vascular disease.
Academic Article Association of plasma ADMA levels with MRI markers of vascular brain injury: Framingham offspring study.
Academic Article Asymmetric dimethylarginine as a mediator of vascular dysfunction and a marker of cardiovascular disease and mortality: an intriguing interaction with diabetes mellitus.
Academic Article Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies.
Academic Article Relation of brachial and digital measures of vascular function in the community: the Framingham heart study.
Academic Article Circulating angiogenic cell populations, vascular function, and arterial stiffness.
Academic Article Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels.
Academic Article Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium.
Academic Article Relation of vascular growth factors with CT-derived measures of body fat distribution: the Framingham Heart Study.
Academic Article Multiple biomarkers and risk of clinical and subclinical vascular brain injury: the Framingham Offspring Study.
Academic Article Relations of exercise blood pressure response to cardiovascular risk factors and vascular function in the Framingham Heart Study.
Academic Article Aortic stiffness, blood pressure progression, and incident hypertension.
Academic Article Circulating vascular growth factors and central hemodynamic load in the community.
Academic Article Thoracic periaortic and visceral adipose tissue and their cross-sectional associations with measures of vascular function.
Academic Article Serum brain-derived neurotrophic factor and vascular endothelial growth factor levels are associated with risk of stroke and vascular brain injury: Framingham Study.
Academic Article Relations of arterial stiffness and endothelial function to brain aging in the community.
Academic Article Vascular inflammation and sleep disordered breathing in a community-based cohort.
Academic Article Aortic stiffness and incident hypertension--reply.
Academic Article Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis.
Academic Article Association of Exhaled Carbon Monoxide With Stroke Incidence and Subclinical Vascular Brain Injury: Framingham Heart Study.
Academic Article Endothelial function, arterial stiffness and adherence to the 2010 Dietary Guidelines for Americans: a cross-sectional analysis.
Academic Article Associations of Circulating Growth Differentiation Factor-15 and ST2 Concentrations With Subclinical Vascular Brain Injury and Incident Stroke.
Academic Article Temporal trends in pulse pressure and mean arterial pressure during the rise of pediatric obesity in US children.
Academic Article Cross-sectional relations of arterial stiffness, pressure pulsatility, wave reflection, and arterial calcification.
Academic Article The relation of red blood cell fatty acids with vascular stiffness, cardiac structure and left ventricular function: the Framingham Heart Study.
Academic Article Short-term exposure to air pollution and digital vascular function.
Academic Article Physical activity measured by accelerometry and its associations with cardiac structure and vascular function in young and middle-aged adults.
Academic Article Association of circulating endothelial microparticles with cardiometabolic risk factors in the Framingham Heart Study.
Academic Article Nonalcoholic fatty liver disease and vascular function: cross-sectional analysis in the Framingham heart study.
Academic Article Aortic root remodeling and risk of heart failure in the Framingham Heart study.
Academic Article Circulating Adipokines and Vascular Function: Cross-Sectional Associations in a Community-Based Cohort.
Academic Article Relations of Central Hemodynamics and Aortic Stiffness with Left Ventricular Structure and Function: The Framingham Heart Study.
Academic Article Circulating vascular endothelial growth factor and the risk of cardiovascular events.
Academic Article Cross-Sectional Associations of Flow Reversal, Vascular Function, and Arterial Stiffness in the Framingham Heart Study.
Academic Article Relation of Central Arterial Stiffness to Incident Heart Failure in the Community.
Academic Article Circulating Sex Steroids and Vascular Calcification in Community-Dwelling Men: The Framingham Heart Study.
Academic Article Effects of Arterial Stiffness on Brain Integrity in Young Adults From the Framingham Heart Study.
Academic Article Relations of circulating GDF-15, soluble ST2, and troponin-I concentrations with vascular function in the community: The Framingham Heart Study.
Academic Article Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies.
Academic Article The association between sleep-disordered breathing and aortic stiffness in a community cohort.
Academic Article Relations Between Aortic Stiffness and Left Ventricular Mechanical Function in the Community.
Academic Article Association of arterial stiffness with progression of subclinical brain and cognitive disease.
Academic Article Circulating biomarkers and incident ischemic stroke in the Framingham Offspring Study.
Academic Article Association of Aortic Stiffness With Cognition and Brain Aging in Young and Middle-Aged Adults: The Framingham Third Generation Cohort Study.
Academic Article Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia.
Academic Article Relations of Arterial Stiffness and Brachial Flow-Mediated Dilation With New-Onset Atrial Fibrillation: The Framingham Heart Study.
Academic Article Association of Parental Hypertension With Arterial Stiffness in Nonhypertensive Offspring: The Framingham Heart Study.
Academic Article Aortic Stiffness and the Risk of Incident Mild Cognitive Impairment and Dementia.
Academic Article Relative Contributions of Arterial Stiffness and Hypertension to Cardiovascular Disease: The Framingham Heart Study.
Academic Article Microvascular Function Contributes to the Relation Between Aortic Stiffness and Cardiovascular Events: The Framingham Heart Study.
Academic Article The association of endothelial function and tone by digital arterial tonometry with MRI left ventricular mass in African Americans: the Jackson Heart Study.
Academic Article Relations of Arterial Stiffness With Postural Change in Mean Arterial Pressure in Middle-Aged Adults: The Framingham Heart Study.
Academic Article Relations of Metabolically Healthy and Unhealthy Obesity to Digital Vascular Function in Three Community-Based Cohorts: A Meta-Analysis.
Academic Article Aortic-Brachial Arterial Stiffness Gradient and Cardiovascular Risk in the Community: The Framingham Heart Study.
Academic Article Aortic Stiffness, Increased White Matter Free Water, and Altered Microstructural Integrity: A Continuum of Injury.
Grant Aldosterone in Vascular Remodeling and Dysfunction
Academic Article Prevalence, Correlates, and Prognosis of Healthy Vascular Aging in a Western Community-Dwelling Cohort: The Framingham Heart Study.
Academic Article Inter-Relations of Orthostatic Blood Pressure Change, Aortic Stiffness, and Brain Structure and Function in Young Adults.
Academic Article Association of Multiorgan Computed Tomographic Phenomap With Adverse Cardiovascular Health Outcomes: The Framingham Heart Study.
Academic Article Relations of mitochondrial genetic variants to measures of vascular function.
Academic Article Vascular risk factor burden and new-onset depression in the community.
Academic Article Metabolic Predictors of Change in Vascular Function: Prospective Associations From a Community-Based Cohort.
Grant Ventricular-vascular coupling in the elderly: lifecourse determinants, trajectories and prognostic significance
Grant Vascular Stiffness as a Precursor of Hypertension in a Middle-aged Cohort
Grant Biomarkers of Metabolic & Vascular Risk in Obesity
Academic Article Clinical Associations of Vascular Stiffness, Microvascular Dysfunction, and Prevalent Cardiovascular Disease in a Black Cohort: The Jackson Heart Study.

Highlights
Search Criteria
  • Vascular
  • cognitive impairment