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Search Results to Vasan S. Ramachandran, MD

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Research Expertise & Professional Interests Vasan S. Ramachandran, M.D., Principal Investigator and Director of the FHS, and Director of the FHS fellowship program in cardiovascular epidemiology for the last 25 years. Dr. Ramachandran is a Professor of Medicine and Epidemiology at BUSM/BUSPH, and Chief, Section of Preventive Medicine and Epidemiology, Department of Medicine, BUSM. He is the Jay & Louis Coffman Professor of Vascular Medicine at BUSM. Dr. Ramachandran is a trained cardiologist with subspecialty training in echocardiography. He is a fellow of the AHA Councils on Epidemiology and Prevention and Functional Genomics and Translational Biology, and a fellow of the American College of Cardiology (ACC). He has extensive experience in supervising trainees at many levels and has taught the foundational core course on Cardiovascular Epidemiology at BUSPH (EP751). He has several active R01 grants from the NHLBI/NIDDK and received two K24 Mid-Career Investigator mentoring grants from the NHLBI. He has mentored several K23 awardees, and is currently the Principal Investigator of a post-doctoral training program (T32) in cardiovascular epidemiology. Overall, he has supervised over 70 trainees during the past 20 years; most are in key positions in academia. He received the Outstanding Mentor awards from the Department of Medicine, BUSM, and the AHA Council on Epidemiology and Prevention, and the prestigious AHA Population Science Award in 2014. Importantly, Dr. Ramachandran’s own peer-reviewed funding spans thematic areas of genetics and genomics, cardiac and vascular remodeling, novel biomarkers, systems biology including proteomics and metabolomics, and stem cell biology. He has a 25-year history in research in cardiovascular epidemiology, including the two years he trained as a FHS fellow (1993-1995). He established the first School of Public Health in India between 1996-1998, serving as its inaugural director and the coordinator of its MPH program. He is the founding member and leader of the international EchoGen consortium, and chairs the Steering Committee of the Chronic Kidney Disease Biomarker Consortium funded by the NIDDK (U01DK085689). He is recognized internationally for translational research in cardiovascular epidemiology and lectures regularly at the AHA early career session on “how to develop a career in translational research and epidemiology/genetics.” He is well equipped to mentor trainees about grant writing having been a member of the Cardiovascular and Sleep (CASE) SRG, and an active reviewer of grants for national and international funding agencies. He served for many years on the NHLBI panel for reviewing K23-K24-K25 career development grants. He is well qualified to mentor trainees in best publication practices and has served until recently as an Associate Editor for Circulation, and the Editor-in-Chief of Circulation: Cardiovascular Genetics. He works directs the Center for Integrative Transdisciplinary Epidemiology within BUSM, that hosts multiple epidemiological datasets, including from multiple cohort studies, national surveys (NHANES), administrative databases and electronic health records; this center will be a valuable data source for trainees. For the last 20 years, Dr. Ramachandran has focused his research on A) the genetic and non-genetic epidemiology of congestive heart failure, including identifying risk factors for the disease, characterizing the subgroups with diastolic heart failure, asymptomatic LV systolic and diastolic dysfunction, and evaluating the role of LV remodeling; B) population-based vascular testing and echocardiography, including identifying biological, environmental, and genetic determinants (correlates) of cardiac structure and function; normative standards; detailed assessment of biomarkers of the process of LV remodeling, including but not limited to role of natriuretic peptides, insulin resistance, cardiac extracellular matrix markers, oxidative stress, inflammation, growth factors; genetics of LV remodeling, LA and aortic structure and gene-environment interactions; brachial artery endothelial function, its correlates and tonometric assessment of large artery function; C) genetic and non-genetic epidemiology of high blood pressure, including characterizing the lifetime risk, rates of progression and risks associated with various degrees of elevation; large artery stiffness and function and role in systolic hypertension in the elderly; genetics of high blood pressure and large artery function; and D) CVD risk estimation in the short, medium- and long-term, with novel biomarkers including genomic biomarkers.
Self-Described Keywords cardiovascular epidemiology

One or more keywords matched the following items that are connected to Ramachandran, Vasan

Item TypeName
Concept Epidemiology
Concept Stroke Volume
Concept Confounding Factors (Epidemiology)
Concept Molecular Epidemiology
Concept Stroke
Academic Article Congestive heart failure in subjects with normal versus reduced left ventricular ejection fraction: prevalence and mortality in a population-based cohort.
Academic Article Elevated midlife blood pressure increases stroke risk in elderly persons: the Framingham Study.
Academic Article Alcohol consumption and risk for congestive heart failure in the Framingham Heart Study.
Academic Article What is normal blood pressure?
Academic Article Natural history of asymptomatic left ventricular systolic dysfunction in the community.
Academic Article A risk score for predicting stroke or death in individuals with new-onset atrial fibrillation in the community: the Framingham Heart Study.
Academic Article Novel approach to examining first cardiovascular events after hypertension onset.
Academic Article Epidemiology of uncontrolled hypertension in the United States.
Academic Article Circulating biomarkers of extracellular matrix remodeling and risk of atherosclerotic events.
Academic Article Aggressive lowering of blood pressure.
Academic Article Risk factors for acute ischaemic stroke in young adults in South India.
Academic Article Association of multiple inflammatory markers with carotid intimal medial thickness and stenosis (from the Framingham Heart Study).
Academic Article Atrial fibrillation is associated with lower cognitive performance in the Framingham offspring men.
Academic Article Carotid artery atherosclerosis, MRI indices of brain ischemia, aging, and cognitive impairment: the Framingham study.
Academic Article Epidemiology of incident heart failure in a contemporary elderly cohort: the health, aging, and body composition study.
Academic Article Association of carotid artery atherosclerosis with circulating biomarkers of extracellular matrix remodeling: the Framingham Offspring Study.
Academic Article Epidemiology of left ventricular false tendons: clinical correlates in the Framingham Heart Study.
Academic Article Association of the endogenous nitric oxide synthase inhibitor ADMA with carotid artery intimal media thickness in the Framingham Heart Study offspring cohort.
Academic Article Relation of disease pathogenesis and risk factors to heart failure with preserved or reduced ejection fraction: insights from the framingham heart study of the national heart, lung, and blood institute.
Academic Article Major lipids, apolipoproteins, and risk of vascular disease.
Academic Article Arterial stiffness and cardiovascular events: the Framingham Heart Study.
Academic Article Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality.
Academic Article Association of plasma ADMA levels with MRI markers of vascular brain injury: Framingham offspring study.
Academic Article Relation of serum leptin with cardiac mass and left atrial dimension in individuals >70 years of age.
Academic Article C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis.
Academic Article Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium.
Academic Article Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies.
Academic Article A systematic assessment of causes of death after heart failure onset in the community: impact of age at death, time period, and left ventricular systolic dysfunction.
Academic Article Biomarkers of extracellular matrix metabolism (MMP-9 and TIMP-1) and risk of stroke, myocardial infarction, and cause-specific mortality: cohort study.
Academic Article Genome-wide meta-analyses identify multiple loci associated with smoking behavior.
Academic Article Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies.
Academic Article Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium.
Academic Article Segment-specific association between plasma homocysteine level and carotid artery intima-media thickness in the Framingham Offspring Study.
Academic Article Epidemiology and clinical course of heart failure with preserved ejection fraction.
Academic Article Cardiac dysfunction and noncardiac dysfunction as precursors of heart failure with reduced and preserved ejection fraction in the community.
Academic Article Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
Academic Article Advances in the epidemiology of heart failure and left ventricular remodeling.
Academic Article Heart failure: pentraxin 3—a marker of diastolic dysfunction and HF?
Academic Article Multiple biomarkers and risk of clinical and subclinical vascular brain injury: the Framingham Offspring Study.
Academic Article Galectin-3, a marker of cardiac fibrosis, predicts incident heart failure in the community.
Academic Article Discriminating clinical features of heart failure with preserved vs. reduced ejection fraction in the community.
Academic Article Association of physical activity and heart failure with preserved vs. reduced ejection fraction in the elderly: the Framingham Heart Study.
Academic Article Serum brain-derived neurotrophic factor and vascular endothelial growth factor levels are associated with risk of stroke and vascular brain injury: Framingham Study.
Academic Article Association of novel biomarkers of cardiovascular stress with left ventricular hypertrophy and dysfunction: implications for screening.
Academic Article Predictors of new-onset heart failure: differences in preserved versus reduced ejection fraction.
Academic Article Relationship of lycopene intake and consumption of tomato products to incident CVD.
Academic Article The epidemiology of "asymptomatic" left ventricular systolic dysfunction: implications for screening
Academic Article A comparison of dobutamine infusion and exercise during radionuclide ventriculography in the evaluation of coronary arterial disease.
Academic Article Epidemiology of heart failure with preserved ejection fraction.
Academic Article Serum Leptin Levels and the Risk of Stroke: The Framingham Study.
Academic Article Association of Exhaled Carbon Monoxide With Stroke Incidence and Subclinical Vascular Brain Injury: Framingham Heart Study.
Academic Article Cardiovascular Health Status and Incidence of Heart Failure in the Framingham Offspring Study.
Academic Article Cohort Profile: The Framingham Heart Study (FHS): overview of milestones in cardiovascular epidemiology.
Academic Article Left ventricular hypertrophy patterns and incidence of heart failure with preserved versus reduced ejection fraction.
Academic Article Genome-wide association study of L-arginine and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine.
Academic Article 50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study.
Academic Article Epidemiology and pathophysiology of mitral valve prolapse: new insights into disease progression, genetics, and molecular basis.
Academic Article Implications of the US cholesterol guidelines on eligibility for statin therapy in the community: comparison of observed and predicted risks in the Framingham Heart Study Offspring Cohort.
Academic Article Associations of Circulating Growth Differentiation Factor-15 and ST2 Concentrations With Subclinical Vascular Brain Injury and Incident Stroke.
Academic Article Atrial flutter: Clinical risk factors and adverse outcomes in the Framingham Heart Study.
Academic Article The Framingham Heart Study and the epidemiology of cardiovascular disease: a historical perspective.
Academic Article Long-term cardiovascular risks associated with an elevated heart rate: the Framingham Heart Study.
Academic Article Preventing heart failure: the role of physical activity.
Academic Article Does low diastolic blood pressure contribute to the risk of recurrent hypertensive cardiovascular disease events? The Framingham Heart Study.
Academic Article Long-term outcomes of secondary atrial fibrillation in the community: the Framingham Heart Study.
Academic Article The Impact of Multipollutant Clusters on the Association Between Fine Particulate Air Pollution and Microvascular Function.
Academic Article Effects of Arterial Stiffness on Brain Integrity in Young Adults From the Framingham Heart Study.
Academic Article Atrial fibrillation without comorbidities: Prevalence, incidence and prognosis (from the Framingham Heart Study).
Academic Article The Future of Cardiovascular Epidemiology.
Academic Article Prognosis of Adults With Borderline Left Ventricular Ejection Fraction.
Academic Article Predicting Heart Failure With Preserved and Reduced Ejection Fraction: The International Collaboration on Heart Failure Subtypes.
Academic Article Response to Letter Regarding Article, "Atrial Fibrillation Begets Heart Failure and Vice Versa: Temporal Associations and Differences in Preserved Versus Reduced Ejection Fraction".
Academic Article Cerebral Microbleeds as Predictors of Mortality: The Framingham Heart Study.
Academic Article Revised Framingham Stroke Risk Profile to Reflect Temporal Trends.
Academic Article A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.
Academic Article Circulating biomarkers and incident ischemic stroke in the Framingham Offspring Study.
Academic Article Atrial Fibrillation Begets Heart Failure and Vice Versa: Temporal Associations and Differences in Preserved Versus Reduced Ejection Fraction.
Academic Article Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia.
Academic Article Aortic Stiffness and the Risk of Incident Mild Cognitive Impairment and Dementia.
Academic Article The association of chronic kidney disease and microalbuminuria with heart failure with preserved vs. reduced ejection fraction.
Academic Article Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia: A Prospective Cohort Study.
Academic Article Association Between HIV Infection and the Risk of Heart Failure With Reduced Ejection Fraction and Preserved Ejection Fraction in the Antiretroviral Therapy Era: Results From the Veterans Aging Cohort Study.
Academic Article Aortic Stiffness, Increased White Matter Free Water, and Altered Microstructural Integrity: A Continuum of Injury.
Academic Article Recent Update to the US Cholesterol Treatment Guidelines: A Comparison With International Guidelines.
Academic Article Epidemiology of cardiovascular disease: recent novel outlooks on risk factors and clinical approaches.
Academic Article Serum Insulin-Like Growth Factor 1 and the Risk of Ischemic Stroke: The Framingham Study.
Academic Article Overweight, Obesity, and Survival After Stroke in the Framingham Heart Study.
Academic Article Association of descending thoracic aortic plaque with brain atrophy and white matter hyperintensities: The Framingham Heart Study.
Academic Article Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology.
Academic Article PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data From 9 Studies of Blacks and Whites.
Academic Article Clinical and Echocardiographic Correlates of Left Atrial Function Index: The Framingham Offspring Study.
Academic Article Epidemiology of Left Ventricular Systolic Dysfunction and Heart Failure in the Framingham Study: An Echocardiographic Study Over 3 Decades.
Academic Article Association of Multiorgan Computed Tomographic Phenomap With Adverse Cardiovascular Health Outcomes: The Framingham Heart Study.
Academic Article Analysis commons, a team approach to discovery in a big-data environment for genetic epidemiology.
Academic Article Vascular risk factor burden and new-onset depression in the community.
Academic Article Predictors and outcomes of heart failure with mid-range ejection fraction.
Academic Article Association of Cardiovascular Biomarkers With Incident Heart Failure With Preserved and Reduced Ejection Fraction.
Academic Article Characteristics and prognosis of heart failure with improved compared with persistently reduced ejection fraction: A systematic review and meta-analyses.
Academic Article Epidemiology of cardiovascular disease in young individuals.
Grant Epidemiology of IGFs and Aging
Grant Multidisciplinary Training Program in Cardiovascular Epidemiology
Academic Article FIB-4 stage of liver fibrosis is associated with incident heart failure with preserved, but not reduced, ejection fraction among people with and without HIV or hepatitis C.

Highlights
Search Criteria
  • Stroke
  • epidemiology