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Search Results to Maria Trojanowska, PhD

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One or more keywords matched the following items that are connected to Trojanowska, Maria

Item TypeName
Concept Growth Inhibitors
Concept Growth Substances
Concept Platelet-Derived Growth Factor
Concept Transforming Growth Factors
Concept Transforming Growth Factor beta
Concept Fibroblast Growth Factor 2
Concept Receptors, Fibroblast Growth Factor
Concept Receptors, Platelet-Derived Growth Factor
Concept Receptors, Transforming Growth Factor beta
Concept Receptor, Platelet-Derived Growth Factor beta
Concept Transforming Growth Factor beta1
Concept Transforming Growth Factor beta2
Concept Connective Tissue Growth Factor
Academic Article Independent effects of platelet-derived growth factor isoforms on mitogen-activated protein kinase activation and mitogenesis in human dermal fibroblasts.
Academic Article Different effects of basic fibroblast growth factor and transforming growth factor-beta on the two platelet-derived growth factor receptors' expression in scleroderma and healthy human dermal fibroblasts.
Academic Article IL-4 upregulates tenascin synthesis in scleroderma and healthy skin fibroblasts.
Academic Article Differential responses of human papillary and reticular fibroblasts to growth factors.
Academic Article Elevated levels of platelet derived growth factor and transforming growth factor-beta 1 in bronchoalveolar lavage fluid from patients with scleroderma.
Academic Article Basic fibroblast growth factor inhibits basal and transforming growth factor-beta induced collagen alpha 2(I) gene expression in scleroderma and normal fibroblasts.
Academic Article Increased expression of TGF-beta receptors by scleroderma fibroblasts: evidence for contribution of autocrine TGF-beta signaling to scleroderma phenotype.
Academic Article Stimulation of type I collagen transcription in human skin fibroblasts by TGF-beta: involvement of Smad 3.
Academic Article Oncostatin M: a cytokine upregulated in human cirrhosis, increases collagen production by human hepatic stellate cells.
Academic Article Mechanisms by which bradykinin promotes fibrosis in vascular smooth muscle cells: role of TGF-beta and MAPK.
Academic Article Interaction of smad3 with a proximal smad-binding element of the human alpha2(I) procollagen gene promoter required for transcriptional activation by TGF-beta.
Academic Article Differential modulation of bFGF receptors by TGF-beta in adult skin, scleroderma skin, and newborn foreskin fibroblasts.
Academic Article Selective upregulation of platelet-derived growth factor alpha receptors by transforming growth factor beta in scleroderma fibroblasts.
Academic Article Differential modulation of bFGF receptors by TGF-beta in adult skin, scleroderma skin, and newborn foreskin fibroblasts.
Academic Article Reversal of activation of human myofibroblast-like cells by culture on a basement membrane-like substrate.
Academic Article Modulation of transforming growth factor-beta (TGF-beta) signaling by endogenous sphingolipid mediators.
Academic Article Selective stimulation of collagen synthesis in the presence of costimulatory insulin signaling by connective tissue growth factor in scleroderma fibroblasts.
Academic Article Differential regulation of transforming growth factor-beta receptors type I and II by platelet-derived growth factor in human dermal fibroblasts.
Academic Article Oncostatin M stimulates tissue inhibitor of metalloproteinase-1 via a MEK-sensitive mechanism in human myofibroblasts.
Academic Article Blockade of the effects of TGF-beta1 on mesangial cells by overexpression of Smad7.
Academic Article Role of p38 MAPK in transforming growth factor beta stimulation of collagen production by scleroderma and healthy dermal fibroblasts.
Academic Article Ets1 is an effector of the transforming growth factor beta (TGF-beta ) signaling pathway and an antagonist of the profibrotic effects of TGF-beta.
Academic Article TGF-beta and CTGF have overlapping and distinct fibrogenic effects on human renal cells.
Academic Article Growth and characterization of fibroblasts obtained from bronchoalveolar lavage of patients with scleroderma.
Academic Article Pulmonary and activation-regulated chemokine stimulates collagen production in lung fibroblasts.
Academic Article Persistent down-regulation of Fli1, a suppressor of collagen transcription, in fibrotic scleroderma skin.
Academic Article Direct demonstration of transcriptional activation of collagen gene expression in systemic sclerosis fibroblasts: insensitivity to TGF beta 1 stimulation.
Academic Article The 72-kilodalton IE-1 protein of human cytomegalovirus (HCMV) is a potent inducer of connective tissue growth factor (CTGF) in human dermal fibroblasts.
Academic Article Sphingosine kinase 1 (SPHK1) is induced by transforming growth factor-beta and mediates TIMP-1 up-regulation.
Academic Article Tenascin-C upregulation by transforming growth factor-beta in human dermal fibroblasts involves Smad3, Sp1, and Ets1.
Academic Article An increased transforming growth factor beta receptor type I:type II ratio contributes to elevated collagen protein synthesis that is resistant to inhibition via a kinase-deficient transforming growth factor beta receptor type II in scleroderma.
Academic Article Lysophosphatidic acid inhibits TGF-beta-mediated stimulation of type I collagen mRNA stability via an ERK-dependent pathway in dermal fibroblasts.
Academic Article Fibroblast expression of the coactivator p300 governs the intensity of profibrotic response to transforming growth factor beta.
Academic Article Platelet derived growth factor induced tenascin-C transcription is phosphoinositide 3-kinase/Akt-dependent and mediated by Ets family transcription factors.
Academic Article Mechanisms of low-density lipoprotein-induced expression of connective tissue growth factor in human aortic endothelial cells.
Academic Article Expression of oncostatin M and its receptors in normal and cirrhotic human liver.
Academic Article Cytokines and human fibrosis.
Academic Article Gene profiling of scleroderma skin reveals robust signatures of disease that are imperfectly reflected in the transcript profiles of explanted fibroblasts.
Academic Article Fli1 and Ets1 have distinct roles in connective tissue growth factor/CCN2 gene regulation and induction of the profibrotic gene program.
Academic Article Increased levels of transforming growth factor beta receptor type I and up-regulation of matrix gene program: A model of scleroderma.
Academic Article Transforming growth factor-beta receptor type I-dependent fibrogenic gene program is mediated via activation of Smad1 and ERK1/2 pathways.
Academic Article Cyr61/CCN1 and CTGF/CCN2 mediate the proangiogenic activity of VHL-mutant renal carcinoma cells.
Academic Article Mitogenic effect of transforming growth factor beta 1 on human fibroblasts involves the induction of platelet-derived growth factor alpha receptors.
Academic Article Transforming growth factor-beta regulates DNA binding activity of transcription factor Fli1 by p300/CREB-binding protein-associated factor-dependent acetylation.
Academic Article GATA-6 is a novel transcriptional repressor of the human Tenascin-C gene expression in fibroblasts.
Academic Article Akt blockade downregulates collagen and upregulates MMP1 in human dermal fibroblasts.
Academic Article Role of PDGF in fibrotic diseases and systemic sclerosis.
Academic Article Persistent effect of TGF-beta 1 on extracellular matrix gene expression in human dermal fibroblasts.
Academic Article Phosphorylation of Fli1 at threonine 312 by protein kinase C delta promotes its interaction with p300/CREB-binding protein-associated factor and subsequent acetylation in response to transforming growth factor beta.
Academic Article Opposite effects of dihydrosphingosine 1-phosphate and sphingosine 1-phosphate on transforming growth factor-beta/Smad signaling are mediated through the PTEN/PPM1A-dependent pathway.
Academic Article Smad1 pathway is activated in systemic sclerosis fibroblasts and is targeted by imatinib mesylate.
Academic Article Akt inhibition up-regulates MMP1 through a CCN2-dependent pathway in human dermal fibroblasts.
Academic Article Establishment and characterization of scleroderma fibroblast clonal cell lines by introduction of the hTERT gene.
Academic Article A strategy for determining the pathogenesis of systemic sclerosis. Is transforming growth factor beta the answer?
Academic Article Noncanonical transforming growth factor beta signaling in scleroderma fibrosis.
Academic Article Genetic variant in the promoter of connective tissue growth factor gene confers susceptibility to nephropathy in type 1 diabetes.
Academic Article Connective tissue growth factor (CTGF/CCN2) mediates angiogenic effect of S1P in human dermal microvascular endothelial cells.
Academic Article Autocrine transforming growth factor ß signaling regulates extracellular signal-regulated kinase 1/2 phosphorylation via modulation of protein phosphatase 2A expression in scleroderma fibroblasts.
Academic Article The c-Abl tyrosine kinase controls protein kinase Cd-induced Fli-1 phosphorylation in human dermal fibroblasts.
Academic Article Endoglin promotes TGF-ß/Smad1 signaling in scleroderma fibroblasts.
Academic Article Fli1 is a negative regulator of estrogen receptor a in dermal fibroblasts.
Academic Article CCN2 is required for the TGF-ß induced activation of Smad1-Erk1/2 signaling network.
Academic Article Elevated expression of cav-1 in a subset of SSc fibroblasts contributes to constitutive Alk1/Smad1 activation.
Academic Article Role of endoglin in fibrosis and scleroderma.
Academic Article Acid sphingomyelinase deficiency contributes to resistance of scleroderma fibroblasts to Fas-mediated apoptosis.
Academic Article Interferon-? promotes vascular remodeling in human microvascular endothelial cells by upregulating endothelin (ET)-1 and transforming growth factor (TGF) ß2.
Academic Article MMP-12 deficiency attenuates angiotensin II-induced vascular injury, M2 macrophage accumulation, and skin and heart fibrosis.
Academic Article Epstein-Barr virus infection induces aberrant TLR activation pathway and fibroblast-myofibroblast conversion in scleroderma.
Academic Article Simultaneous downregulation of KLF5 and Fli1 is a key feature underlying systemic sclerosis.
Academic Article Fli1 represses transcription of the human a2(I) collagen gene by recruitment of the HDAC1/p300 complex.
Academic Article Adenosine A(2A) receptors promote collagen production by a Fli1- and CTGF-mediated mechanism.
Academic Article Fibrosis, vascular activation, and immune abnormalities resembling systemic sclerosis in bleomycin-treated Fli-1-haploinsufficient mice.
Academic Article Glycyrrhizin Ameliorates Fibrosis, Vasculopathy, and Inflammation in Animal Models of Systemic Sclerosis.
Academic Article PDGFRß Is a Novel Marker of Stromal Activation in Oral Squamous Cell Carcinomas.
Academic Article Blockade of PDGF Receptors by Crenolanib Has Therapeutic Effect in Patient Fibroblasts and in Preclinical Models of Systemic Sclerosis.
Academic Article Anti-connective tissue growth factor (CTGF/CCN2) monoclonal antibody attenuates skin fibrosis in mice models of systemic sclerosis.
Academic Article Therapeutic Targeting of TAZ and YAP by Dimethyl Fumarate in Systemic Sclerosis Fibrosis.
Academic Article The Activation of Human Dermal Microvascular Cells by Poly(I:C), Lipopolysaccharide, Imiquimod, and ODN2395 Is Mediated by the Fli1/FOXO3A Pathway.

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