Search Results to Esther Bullitt, PhD

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Research Expertise & Professional Interests Structural studies of biological macromolecular assemblies are providing an understanding of cellular function. In our laboratory, we utilize electron microscopy and image reconstruction to investigate questions about microbial virulence. Work in the lab currently focuses on bacterial adhesion pili (fimbriae), type III secretion system needles, and virus replication. These projects address basic medical research questions directed at understanding bacterial adhesion to human host tissue and viral replication. Our data support development of novel therapeutics targeting these important health issues including, for example, development of a vaccine against traveler’s diarrhea.
Self-Described Keywords Structural biology

One or more keywords matched the following items that are connected to Bullitt, Esther

Item TypeName
Concept Microscopy, Electron
Concept Microscopy, Electron, Scanning
Concept Models, Structural
Concept Structural Homology, Protein
Concept Microscopy, Electron, Transmission
Academic Article Development of pilus organelle subassemblies in vitro depends on chaperone uncapping of a beta zipper.
Academic Article The yeast spindle pole body is assembled around a central crystal of Spc42p.
Academic Article Bacterial adhesion pili are heterologous assemblies of similar subunits.
Academic Article Electron microscopy and x-ray diffraction studies of Lotus tetragonolobus A isolectin cross-linked with a divalent Lewisx oligosaccharide, an oncofetal antigen.
Academic Article Structure and function of Hib pili from Haemophilus influenzae type b.
Academic Article Visualization and functional analysis of RNA-dependent RNA polymerase lattices.
Academic Article Localization of a critical interface for helical rod formation of bacterial adhesion P-pili.
Academic Article Crystal structure of the P pilus rod subunit PapA.
Academic Article The three-dimensional structure of CFA/I adhesion pili: traveler's diarrhea bacteria hang on by a spring.
Academic Article Structure of flexible filamentous plant viruses.
Academic Article Giardia cyst wall protein 1 is a lectin that binds to curled fibrils of the GalNAc homopolymer.
Academic Article A structural basis for sustained bacterial adhesion: biomechanical properties of CFA/I pili.
Academic Article Ultrastructural analysis of IpaD at the tip of the nascent MxiH type III secretion apparatus of Shigella flexneri.
Academic Article ß-1,3-glucan, which can be targeted by drugs, forms a trabecular scaffold in the oocyst walls of Toxoplasma and Eimeria.
Academic Article Surface for catalysis by poliovirus RNA-dependent RNA polymerase.
Academic Article Structural polymorphism of bacterial adhesion pili.
Academic Article Three-dimensional reconstruction of an actin bundle.
Academic Article A model for fibrinogen: domains and sequence.
Academic Article Haemophilus influenzae pili are composite structures assembled via the HifB chaperone.
Academic Article Snapshots of usher-mediated protein secretion and ordered pilus assembly.
Academic Article Biomechanical and structural features of CS2 fimbriae of enterotoxigenic Escherichia coli.
Academic Article The Role of Electron Microscopy in Studying the Continuum of Changes in Membranous Structures during Poliovirus Infection.
Academic Article Structure and function of enterotoxigenic Escherichia coli fimbriae from differing assembly pathways.
Academic Article Cryo-EM reveals the structural basis of long-range electron transport in a cytochrome-based bacterial nanowire.

Search Criteria
  • structural
  • electron microscopy