Connection

Search Results to Lindsay Farrer, PhD

This is a "connection" page, showing the details of why an item matched the keywords from your search.

Search Results

Farrer, Lindsay

One or more keywords matched the following properties of Farrer, Lindsay

Property	Value
Research Expertise & Professional Interests	Dr. Lindsay Farrer is a medical geneticist at Boston University Schools of Medicine and Public Health where he is the Boston University Distinguished Professor of Genetics, Chief of Biomedical Genetics, and a Professor of Medicine, Neurology, Ophthalmology, Epidemiology, and Biostatistics. Dr. Farrer is a graduate of the University of North Carolina in Chapel Hill, received his Ph.D. from the Indiana University School of Medicine, and gained additional training in genetic epidemiology at Yale University. He holds adjunct faculty positions at Harvard Medical School, Massachusetts General Hospital, and the Veterans Administration Medical Center in Bedford, Massachusetts. He is a Founding Fellow of the American College of Medical Genetics. Dr. Farrer teaches several courses in human genetics and addiction science at Boston University, directs the BU Transformative Training Program in Addiction Science (TTPAS) that features transdisciplinary training for students enrolled in PhD programs across the Medical and Charles River campuses, directs Boston University’s Molecular Genetics Core Facility which offers DNA genotyping and sequencing services to investigators at Boston University and elsewhere, and provides genetic counseling and testing to patients with a variety of inherited conditions. Dr. Farrer’s research has lead to more than 450 publications on genetic risk factors for several familial neurodegenerative and other chronic diseases. In collaboration with other laboratories worldwide, his group has localized genes causing a variety of rare and common disorders, most notably Alzheimer disease (AD), substance use disorders (SUDs), age-related macular degeneration (AMD), Wilson disease, Machado-Joseph disease, Waardenburg syndrome, hypertension, sensorineural deafness, and osteoarthritis. His group identified a functional genetic variant in the complement factor H gene which accounts for more than 30% of the attributable risk for AMD, the leading cause of progressive vision loss and blindness in the elderly. In collaboration with other researchers, Dr. Farrer is conducting genome wide association studies (GWAS) and whole genome/exome sequencing studies for several disorders including AD, SUDs (cocaine, opiates, nicotine, alcohol and cannabis), and AMD. Dr. Farrer’s team is also developing methods for locating genes that influence the natural history of complex diseases and pharmacogenetic response. Under Dr. Farrer’s leadership, the MIRAGE Project, a multi-center study of AD funded since 1991 by the National Institute on Aging, has made several important contributions to our understanding of the interactions between genetic and environmental factors for the disorder. This study has a particular emphasis on the genetics of AD in African Americans. MIRAGE was the first study to demonstrate that genetic factors have a major role in the development of AD and that APOE e4 is more weakly associated with disease in men and persons older than 75 years. Dr. Farrer co-directed the international effort which demonstrated that SORL1 is genetically and functionally associated with AD, thus implicating intracellular protein trafficking as integral pathway in AD. His laboratory conducted genome wide association studies (GWAS) for AD in several populations including African Americans and an inbred Israeli-Arab community, and identified rare AD causal mutations in the AKAP9 gene which are specific to African Americans. Dr. Farrer serves on the Executive Committee of the national Alzheimer Disease Genetics Consortium and co-directs the data analysis effort for this large NIH-funded project. He is also a Principal Investigator of the national Alzheimer Disease Sequencing Project and a study to identify AD risk and protective variants in Koreans.
Self-Described Keywords	Alzheimer disease

Property

Value

Research Expertise & Professional Interests

Dr. Lindsay Farrer is a medical geneticist at Boston University Schools of Medicine and Public Health where he is the Boston University Distinguished Professor of Genetics, Chief of Biomedical Genetics, and a Professor of Medicine, Neurology, Ophthalmology, Epidemiology, and Biostatistics. Dr. Farrer is a graduate of the University of North Carolina in Chapel Hill, received his Ph.D. from the Indiana University School of Medicine, and gained additional training in genetic epidemiology at Yale University. He holds adjunct faculty positions at Harvard Medical School, Massachusetts General Hospital, and the Veterans Administration Medical Center in Bedford, Massachusetts. He is a Founding Fellow of the American College of Medical Genetics. Dr. Farrer teaches several courses in human genetics and addiction science at Boston University, directs the BU Transformative Training Program in Addiction Science (TTPAS) that features transdisciplinary training for students enrolled in PhD programs across the Medical and Charles River campuses, directs Boston University’s Molecular Genetics Core Facility which offers DNA genotyping and sequencing services to investigators at Boston University and elsewhere, and provides genetic counseling and testing to patients with a variety of inherited conditions. Dr. Farrer’s research has lead to more than 450 publications on genetic risk factors for several familial neurodegenerative and other chronic diseases. In collaboration with other laboratories worldwide, his group has localized genes causing a variety of rare and common disorders, most notably Alzheimer disease (AD), substance use disorders (SUDs), age-related macular degeneration (AMD), Wilson disease, Machado-Joseph disease, Waardenburg syndrome, hypertension, sensorineural deafness, and osteoarthritis. His group identified a functional genetic variant in the complement factor H gene which accounts for more than 30% of the attributable risk for AMD, the leading cause of progressive vision loss and blindness in the elderly. In collaboration with other researchers, Dr. Farrer is conducting genome wide association studies (GWAS) and whole genome/exome sequencing studies for several disorders including AD, SUDs (cocaine, opiates, nicotine, alcohol and cannabis), and AMD. Dr. Farrer’s team is also developing methods for locating genes that influence the natural history of complex diseases and pharmacogenetic response. Under Dr. Farrer’s leadership, the MIRAGE Project, a multi-center study of AD funded since 1991 by the National Institute on Aging, has made several important contributions to our understanding of the interactions between genetic and environmental factors for the disorder. This study has a particular emphasis on the genetics of AD in African Americans. MIRAGE was the first study to demonstrate that genetic factors have a major role in the development of AD and that APOE e4 is more weakly associated with disease in men and persons older than 75 years. Dr. Farrer co-directed the international effort which demonstrated that SORL1 is genetically and functionally associated with AD, thus implicating intracellular protein trafficking as integral pathway in AD. His laboratory conducted genome wide association studies (GWAS) for AD in several populations including African Americans and an inbred Israeli-Arab community, and identified rare AD causal mutations in the AKAP9 gene which are specific to African Americans. Dr. Farrer serves on the Executive Committee of the national Alzheimer Disease Genetics Consortium and co-directs the data analysis effort for this large NIH-funded project. He is also a Principal Investigator of the national Alzheimer Disease Sequencing Project and a study to identify AD risk and protective variants in Koreans.

Self-Described Keywords

Alzheimer disease

One or more keywords matched the following items that are connected to Farrer, Lindsay

Item Type	Name
Concept	Alleles
Concept	Alzheimer Disease
Concept	Amino Acid Sequence
Concept	Amyotrophic Lateral Sclerosis
Concept	Anemia, Sickle Cell
Concept	Anti-Inflammatory Agents, Non-Steroidal
Concept	Base Sequence
Concept	Behavioral Symptoms
Concept	Binding Sites
Concept	Brain Diseases
Concept	Cardiovascular Diseases
Concept	Charcot-Marie-Tooth Disease
Concept	Computer Simulation
Concept	Coronary Artery Disease
Concept	Cross-Sectional Studies
Concept	Data Interpretation, Statistical
Concept	Disease
Concept	Disease Models, Animal
Concept	Disease Susceptibility
Concept	Diseases in Twins
Concept	DNA, Satellite
Concept	Drug Synergism
Concept	Educational Status
Concept	Endocrine System Diseases
Concept	Epistasis, Genetic
Concept	Evaluation Studies as Topic
Concept	Factor Analysis, Statistical
Concept	Feasibility Studies
Concept	Follow-Up Studies
Concept	Fragile X Syndrome
Concept	Genes
Concept	Genes, Dominant
Concept	Genes, Homeobox
Concept	Genes, Recessive
Concept	Multigene Family
Concept	Health Status
Concept	Health Surveys
Concept	Heat-Shock Proteins
Concept	Hemoglobin, Sickle
Concept	Hirschsprung Disease
Concept	Huntington Disease
Concept	Information Systems
Concept	Length of Stay
Concept	Lod Score
Concept	Longitudinal Studies
Concept	Major Histocompatibility Complex
Concept	Marijuana Smoking
Concept	Mass Screening
Concept	Mental Status Schedule
Concept	Mice, Inbred Strains
Concept	Mice, Mutant Strains
Concept	Molecular Sequence Data
Concept	Neonatal Abstinence Syndrome
Concept	S100 Proteins
Concept	Synaptic Transmission
Concept	Organ Specificity
Concept	Organ Size
Concept	Parkinson Disease
Concept	Population Surveillance
Concept	Prospective Studies
Concept	Psychiatric Status Rating Scales
Concept	Psychoses, Substance-Induced
Concept	Receptors, Cell Surface
Concept	Receptors, Serotonin
Concept	Reference Standards
Concept	Regulatory Sequences, Nucleic Acid
Concept	Repetitive Sequences, Nucleic Acid
Concept	Retrospective Studies
Concept	Saliva
Concept	Schizophrenia
Concept	Schizophrenic Psychology
Concept	Sclerosis
Concept	Scotland
Concept	Self-Help Groups
Concept	Sensitivity and Specificity
Concept	Serine
Concept	Severity of Illness Index
Concept	Sexual Behavior
Concept	Sex Characteristics
Concept	Sex Chromosome Aberrations
Concept	Sex Factors
Concept	Skin Neoplasms
Concept	Skinfold Thickness
Concept	Sleep
Concept	Smoking
Concept	Social Environment
Concept	Socioeconomic Factors
Concept	Software
Concept	Solubility
Concept	Spain
Concept	Species Specificity
Concept	Spinal Puncture
Concept	Spinocerebellar Degenerations
Concept	Statistics as Topic
Concept	Stem Cells
Concept	Street Drugs
Concept	Stress Disorders, Post-Traumatic
Concept	Stress, Psychological
Concept	Structure-Activity Relationship
Concept	Substance Withdrawal Syndrome
Concept	Suicide
Concept	Suicide, Attempted
Concept	Sulfonylurea Compounds
Concept	Sweden
Concept	Switzerland
Concept	Sympathetic Nervous System
Concept	United States
Concept	Waardenburg Syndrome
Concept	Blotting, Southern
Concept	Models, Statistical
Concept	Sulfotransferases
Concept	Deoxyribonucleases, Type II Site-Specific
Concept	Cohort Studies
Concept	Molecular Structure
Concept	Signal Transduction
Concept	Trauma Severity Indices
Concept	Gene Library
Concept	Substance Abuse, Intravenous
Concept	Genome, Human
Concept	Tomography, Emission-Computed, Single-Photon
Concept	Selection Bias
Concept	Chi-Square Distribution
Concept	Least-Squares Analysis
Concept	Survival Analysis
Concept	Epidemiologic Studies
Concept	Case-Control Studies
Concept	Sequence Tagged Sites
Concept	Open Reading Frames
Concept	Sequence Alignment
Concept	Needle Sharing
Concept	Genes, Neurofibromatosis 1
Concept	Smoking Cessation
Concept	Genome
Concept	Protein-Serine-Threonine Kinases
Concept	Sequence Deletion
Concept	Sequence Homology, Amino Acid
Concept	Sequence Analysis, DNA
Concept	Sequence Analysis, RNA
Concept	Protein Structure, Secondary
Concept	Protein Structure, Tertiary
Concept	Marital Status
Concept	Sex Distribution
Concept	Machado-Joseph Disease
Concept	Genes, Reporter
Concept	Oxidative Stress
Concept	Sample Size
Concept	Disease Progression
Concept	Patient Selection
Concept	Statistics, Nonparametric
Concept	Sepsis
Concept	HSP70 Heat-Shock Proteins
Concept	Staurosporine
Concept	Neurodegenerative Diseases
Concept	Amino Acid Substitution
Concept	Substance-Related Disorders
Concept	Calcium Signaling
Concept	Genetic Predisposition to Disease
Concept	Catalytic Domain
Concept	Alcohol-Induced Disorders, Nervous System
Concept	Alcohol Withdrawal Seizures
Concept	Oligonucleotide Array Sequence Analysis
Concept	Stroke
Concept	Genes, myb
Concept	Polymorphism, Single Nucleotide
Concept	RNA Splice Sites
Concept	Electrophoretic Mobility Shift Assay
Concept	Metabolic Syndrome X
Concept	Tumor Suppressor Proteins
Concept	Amino Acid Transport Systems, Basic
Concept	Symporters
Concept	Organic Anion Transporters, Sodium-Dependent
Concept	Genetic Diseases, Inborn
Concept	RNA, Small Interfering
Concept	Siblings
Concept	Diagnostic and Statistical Manual of Mental Disorders
Concept	Pluripotent Stem Cells
Concept	Semaphorins
Concept	Semaphorin-3A
Concept	Quantitative Trait Loci
Concept	DNA Repeat Expansion
Concept	Receptor, Serotonin, 5-HT2B
Concept	Unsafe Sex
Concept	Intracellular Signaling Peptides and Proteins
Concept	Adaptor Proteins, Signal Transducing
Concept	Saposins
Concept	Systems Biology
Concept	Serotonin Plasma Membrane Transport Proteins
Concept	STAT6 Transcription Factor
Concept	Smad3 Protein
Concept	Smad6 Protein
Concept	Nitric Oxide Synthase Type I
Concept	Nitric Oxide Synthase Type III
Concept	CARD Signaling Adaptor Proteins
Concept	Amyloid Precursor Protein Secretases
Concept	Adult Survivors of Child Abuse
Concept	Genome-Wide Association Study
Concept	Protein Stability
Concept	Genetic Loci
Concept	Sirtuin 1
Concept	Genetic Association Studies
Concept	Endosomal Sorting Complexes Required for Transport
Concept	Nuclear Receptor Subfamily 1, Group F, Member 1
Concept	Mice, 129 Strain
Concept	Sorting Nexins
Concept	Genetic Pleiotropy
Concept	Molecular Sequence Annotation
Concept	High-Throughput Nucleotide Sequencing
Concept	Suicidal Ideation
Concept	Transcriptome
Concept	Exome
Concept	Support Vector Machine
Concept	Wnt Signaling Pathway
Concept	Molecular Docking Simulation
Concept	Sialic Acid Binding Ig-like Lectin 3
Concept	Sulfonylurea Receptors
Academic Article	Statement on use of apolipoprotein E testing for Alzheimer disease. American College of Medical Genetics/American Society of Human Genetics Working Group on ApoE and Alzheimer disease.
Academic Article	Apolipoprotein E genotype in patients with Alzheimer's disease: implications for the risk of dementia among relatives.
Academic Article	Allele epsilon 4 of apolipoprotein E shows a dose effect on age at onset of Pick disease.
Academic Article	Identification of the genetic locus for keratosis palmaris et plantaris on chromosome 17 near the RARA and keratin type I genes.
Academic Article	[Mapping the gene for palmoplantar hyperkeratosis (thylosis) to chromosome 17 in the 17q12-q24 region].
Academic Article	Correlation between CAG repeat length and clinical features in Machado-Joseph disease.
Academic Article	A contiguous linkage map of chromosome 13q with 39 distinct loci separated on average by 5.1 centimorgans.
Academic Article	Rate of progression of Alzheimer's disease is associated with genetic risk.
Academic Article	Machado Joseph disease maps to the same region of chromosome 14 as the spinocerebellar ataxia type 3 locus.
Academic Article	A population-based study of familial Alzheimer disease: linkage to chromosomes 14, 19, and 21.
Academic Article	Locus heterogeneity for Waardenburg syndrome is predictive of clinical subtypes.
Academic Article	46,XY/47,XYY male with the fragile X syndrome: cytogenetic and molecular studies.
Academic Article	Polymorphic microsatellites and Wilson disease (WD).
Academic Article	A 4.5-megabase yeast artificial chromosome contig from human chromosome 13q14.3 ordering 9 polymorphic microsatellites (22 sequence-tagged sites) tightly linked to the Wilson disease locus.
Academic Article	Refining the position of Wilson disease by linkage disequilibrium with polymorphic microsatellites.
Academic Article	Estimating the probability for major gene Alzheimer disease.
Academic Article	Susceptibility genes for familial Alzheimer's disease on chromosomes 19 and 21: a reality check.
Academic Article	The normal Huntington disease (HD) allele, or a closely linked gene, influences age at onset of HD.
Academic Article	Genetic transmission of Alzheimer's disease among families in a Dutch population based study.
Academic Article	Linkage of congenital, recessive deafness (DFNB4) to chromosome 7q31 and evidence for genetic heterogeneity in the Middle Eastern Druze population.
Academic Article	Linkage of congenital recessive deafness (gene DFNB10) to chromosome 21q22.3.
Academic Article	A familial factor independent of CAG repeat length influences age at onset of Machado-Joseph disease.
Academic Article	Presenilin polymorphisms in Alzheimer's disease.
Academic Article	No genetic effect of alpha1-antichymotrypsin in Alzheimer disease.
Academic Article	Risk of dementia among relatives of Alzheimer's disease patients in the MIRAGE study: What is in store for the oldest old?
Academic Article	Linkage of polymorphic congenital cataract to the gamma-crystallin gene locus on human chromosome 2q33-35.
Academic Article	Evidence for major gene inheritance of Alzheimer disease in families of patients with and without apolipoprotein E epsilon 4.
Academic Article	A novel mutation in the MITF gene causes Waardenburg syndrome type 2.
Academic Article	Linkage disequilibrium analysis in Machado-Joseph disease patients of different ethnic origins.
Academic Article	No association between alpha 1-antichymotrypsin and familial Alzheimer's disease.
Academic Article	The clinical introduction of genetic testing for Alzheimer disease. An ethical perspective.
Academic Article	No association or linkage between an intronic polymorphism of presenilin-1 and sporadic or late-onset familial Alzheimer disease.
Academic Article	Apolipoprotein E epsilon2 does not increase risk of early-onset sporadic Alzheimer's disease.
Academic Article	Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium.
Academic Article	Novel ATP7B mutations causing Wilson disease in several Israeli ethnic groups.
Academic Article	Amyloid-beta-protein isoforms in brain of subjects with PS1-linked, beta APP-linked and sporadic Alzheimer disease.
Academic Article	Absence of association between Alzheimer disease and the -491 regulatory region polymorphism of APOE.
Academic Article	Evidence for an Alzheimer disease susceptibility locus on chromosome 12 and for further locus heterogeneity.
Academic Article	Smoking and risk of Alzheimer's disease. MIRAGE Study Group.
Academic Article	Association between bleomycin hydrolase and Alzheimer's disease in caucasians.
Academic Article	An alpha-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease.
Academic Article	Alpha-2 macroglobulin gene in early- and late-onset Alzheimer disease.
Academic Article	Detecting linkage for a complex disease using simulated extended pedigrees.
Academic Article	Analysis of the butyrylcholinesterase gene and nearby chromosome 3 markers in Alzheimer disease.
Academic Article	Correlation between Waardenburg syndrome phenotype and genotype in a population of individuals with identified PAX3 mutations.
Academic Article	Autosomal dominant orthostatic hypotensive disorder maps to chromosome 18q.
Academic Article	A family history study of male sexual orientation using three independent samples.
Academic Article	Evidence for linkage between essential hypertension and a putative locus on human chromosome 17.
Academic Article	Identification of a polymorphic glutamic acid stretch in the alpha2B-adrenergic receptor and lack of linkage with essential hypertension.
Academic Article	No association between the HLA-A2 allele and Alzheimer disease.
Academic Article	Familial risk for Alzheimer disease in ethnic minorities: nondiscriminating genes.
Academic Article	Power of concordant versus discordant sib pairs at different penetrance levels.
Academic Article	Stratification techniques to explore genotype environment interactions.
Academic Article	Association between angiotensin-converting enzyme and Alzheimer disease.
Academic Article	Intercontinental epidemiology of Alzheimer disease: a global approach to bad gene hunting.
Academic Article	Highly polymorphic short tandem repeat analyses clarify complex molecular test results.
Academic Article	Genetic predisposition to stroke in relatives of hypertensives.
Academic Article	No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease.
Academic Article	Head injury and the risk of AD in the MIRAGE study.
Academic Article	Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing.
Academic Article	Reliability of information collected by proxy in family studies of Alzheimer's disease.
Academic Article	Distinguishable effects of presenilin-1 and APP717 mutations on amyloid plaque deposition.
Academic Article	The angiotensin-converting enzyme gene as a possible risk or protective factor in Alzheimer's disease.
Academic Article	Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14.
Academic Article	Maternal component in the familial aggregation of hypertension.
Academic Article	Mutations in the open reading frame of the beta-site APP cleaving enzyme (BACE) locus are not a common cause of Alzheimer's disease.
Academic Article	The human cationic amino acid transporter (ATRC1): physical and genetic mapping to 13q12-q14.
Academic Article	Waardenburg syndrome (WS) type I is caused by defects at multiple loci, one of which is near ALPP on chromosome 2: first report of the WS consortium.
Academic Article	Risk of dementia among white and African American relatives of patients with Alzheimer disease.
Academic Article	Association between apolipoprotein E genotype and Alzheimer disease in African American subjects.
Academic Article	Genetic and environmental risk factors for Alzheimer's disease in Israeli Arabs.
Academic Article	Regulatory region variability in the human presenilin-2 (PSEN2) gene: potential contribution to the gene activity and risk for AD.
Academic Article	Monozygotic twins concordant for late-onset probable Alzheimer disease with suspected Alzheimer disease in four sibs.
Academic Article	Identification of multiple loci for Alzheimer disease in a consanguineous Israeli-Arab community.
Academic Article	Comparison of Alzheimer's disease risk factors in white and African American families.
Academic Article	Genetic variants of WNK4 in whites and African Americans with hypertension.
Academic Article	Reasons for seeking genetic susceptibility testing among first-degree relatives of people with Alzheimer disease.
Academic Article	Differences between African Americans and Whites in their attitudes toward genetic testing for Alzheimer's disease.
Academic Article	Depression as a risk factor for Alzheimer disease: the MIRAGE Study.
Academic Article	Genetic and environmental epidemiology of Alzheimer's disease in arabs residing in Israel.
Academic Article	The genetics of adult-onset neuropsychiatric disease: complexities and conundra?
Academic Article	Polymorphisms near a chromosome 6q QTL area are associated with modulation of fetal hemoglobin levels in sickle cell anemia.
Academic Article	The Machado-Joseph disease locus is different from the spinocerebellar ataxia locus (SCA1).
Academic Article	Empirically derived phenotypic subgroups - qualitative and quantitative trait analyses.
Academic Article	Search for genetic factors predisposing to atherogenic dyslipidemia.
Academic Article	Genome-wide screen for heavy alcohol consumption.
Academic Article	Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms.
Academic Article	Segregation analysis of total nevus density and estimation of lifetime risk and average onset age of melanoma.
Academic Article	Estimating risk curves for first-degree relatives of patients with Alzheimer's disease: the REVEAL study.
Academic Article	Who seeks genetic susceptibility testing for Alzheimer's disease? Findings from a multisite, randomized clinical trial.
Academic Article	Analysis of the glucocerebrosidase gene in Parkinson's disease.
Academic Article	Postmenopausal hormone therapy and Alzheimer's disease risk: interaction with age.
Academic Article	Association of single nucleotide polymorphisms in klotho with priapism in sickle cell anaemia.
Academic Article	Relation between atherogenic dyslipidemia and the Adult Treatment Program-III definition of metabolic syndrome (Genetic Epidemiology of Metabolic Syndrome Project).
Academic Article	Polymorphisms in the promoter region of catalase gene and essential hypertension.
Academic Article	Hemolysis-associated priapism in sickle cell disease.
Academic Article	Estimation of morbid risk and age at onset with missing information.
Academic Article	Patterns of inheritance of the symptoms of Huntington's disease suggestive of an effect of genomic imprinting.
Academic Article	Multifactor-dimensionality reduction versus family-based association tests in detecting susceptibility loci in discordant sib-pair studies.
Academic Article	Whole-genome variance components linkage analysis using single-nucleotide polymorphisms versus microsatellites on quantitative traits of derived phenotypes from factor analysis of electroencephalogram waves.
Academic Article	Genome-wide linkage analysis for alcohol dependence: a comparison between single-nucleotide polymorphism and microsatellite marker assays.
Academic Article	Nonsteroidal anti-inflammatory drug use and Alzheimer's disease risk: the MIRAGE Study.
Academic Article	Complement factor H polymorphism and age-related macular degeneration.
Academic Article	Association of klotho, bone morphogenic protein 6, and annexin A2 polymorphisms with sickle cell osteonecrosis.
Academic Article	Rating the severity and character of transient cocaine-induced delusions and hallucinations with a new instrument, the Scale for Assessment of Positive Symptoms for Cocaine-Induced Psychosis (SAPS-CIP).
Academic Article	Diagnostic reliability of the Semi-structured Assessment for Drug Dependence and Alcoholism (SSADDA).
Academic Article	Genomewide linkage scan for cocaine dependence and related traits: significant linkages for a cocaine-related trait and cocaine-induced paranoia.
Academic Article	APOE, vascular pathology, and the AD brain.
Academic Article	Multiple QTLs influencing triglyceride and HDL and total cholesterol levels identified in families with atherogenic dyslipidemia.
Academic Article	An alpha satellite DNA polymorphism specific for the centromeric region of chromosome 13.
Academic Article	Polymorphisms in the PON gene cluster are associated with Alzheimer disease.
Academic Article	Association of asthma with a functional promoter polymorphism in the IL16 gene.
Academic Article	The serotonin receptor subtype 2 locus HTR2 is on human chromosome 13 near genes for esterase D and retinoblastoma-1 and on mouse chromosome 14.
Academic Article	Risk factors for cocaine-induced paranoia in cocaine-dependent sibling pairs.
Academic Article	Intronic variants in the dopa decarboxylase (DDC) gene are associated with smoking behavior in European-Americans and African-Americans.
Academic Article	Association studies between the plasmin genes and late-onset Alzheimer's disease.
Academic Article	Predictive testing for Wilson's disease using tightly linked and flanking DNA markers.
Academic Article	Predictors of subjective memory complaint in cognitively normal relatives of patients with Alzheimer's disease.
Academic Article	Education effects on cognitive function in a healthy aged Arab population.
Academic Article	Genomewide linkage scan for nicotine dependence: identification of a chromosome 5 risk locus.
Academic Article	Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations.
Academic Article	Diabetes mellitus and risk of developing Alzheimer disease: results from the Framingham Study.
Academic Article	Fetal hemoglobin in sickle cell anemia: genetic determinants of response to hydroxyurea.
Academic Article	Genomewide linkage scan for opioid dependence and related traits.
Academic Article	Association of polymorphisms in the Angiotensin-converting enzyme gene with Alzheimer disease in an Israeli Arab community.
Academic Article	Sickle cell leg ulcers: associations with haemolysis and SNPs in Klotho, TEK and genes of the TGF-beta/BMP pathway.
Academic Article	Genetic association between endothelial nitric oxide synthase and Alzheimer disease.
Academic Article	Association of polymorphisms of IGF1R and genes in the transforming growth factor- beta /bone morphogenetic protein pathway with bacteremia in sickle cell anemia.
Academic Article	Serum heat shock protein 70 level as a biomarker of exceptional longevity.
Academic Article	Estimated glomerular filtration rate in sickle cell anemia is associated with polymorphisms of bone morphogenetic protein receptor 1B.
Academic Article	The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease.
Academic Article	Segregation analysis reveals evidence of a major gene for Alzheimer disease.
Academic Article	The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort.
Academic Article	Association of decreased paternal age and late-onset Alzheimer's disease. An example of genetic imprinting?
Academic Article	Potential ethnic modifiers in the assessment and treatment of Alzheimer's disease: challenges for the future.
Academic Article	The validity of cocaine dependence subtypes.
Academic Article	Reliability of DSM-IV diagnostic criteria using the semi-structured assessment for drug dependence and alcoholism (SSADDA).
Academic Article	A network model to predict the risk of death in sickle cell disease.
Academic Article	Variation and heritability of Hb F and F-cells among beta-thalassemia heterozygotes in Hong Kong.
Academic Article	Heritability of magnetic resonance imaging (MRI) traits in Alzheimer disease cases and their siblings in the MIRAGE study.
Academic Article	Comorbid psychiatric diagnoses and their association with cocaine-induced psychosis in cocaine-dependent subjects.
Academic Article	Beta-globin gene cluster polymorphisms are strongly associated with severity of HbE/beta(0)-thalassemia.
Academic Article	Association between SORL1 and Alzheimer's disease in a genome-wide study.
Academic Article	Further examination of the candidate genes in chromosome 12p13 locus for late-onset Alzheimer disease.
Academic Article	Incorporating ethnicity into genetic risk assessment for Alzheimer disease: the REVEAL study experience.
Academic Article	Collection of clinical and epidemiological data for linkage studies.
Academic Article	Substance dependence low-density whole genome association study in two distinct American populations.
Academic Article	Transmission and age-at-onset patterns in familial Alzheimer's disease: evidence for heterogeneity.
Academic Article	Estimation of familial risk in Alzheimer's disease.
Academic Article	Association of psychiatric and substance use disorder comorbidity with cocaine dependence severity and treatment utilization in cocaine-dependent individuals.
Academic Article	Dense genomewide linkage scan for alcohol dependence in African Americans: significant linkage on chromosome 10.
Academic Article	Interaction between two independent CNR1 variants increases risk for cocaine dependence in European Americans: a replication study in family-based sample and population-based sample.
Academic Article	Association of distinct variants in SORL1 with cerebrovascular and neurodegenerative changes related to Alzheimer disease.
Academic Article	Association of variants in MANEA with cocaine-related behaviors.
Academic Article	Performance of random forest when SNPs are in linkage disequilibrium.
Academic Article	Sources of unreliability in the diagnosis of substance dependence.
Academic Article	Correlates of co-occurring ADHD in drug-dependent subjects: prevalence and features of substance dependence and psychiatric disorders.
Academic Article	Lack of association between angiotensin-converting enzyme and dementia of the Alzheimer's type in an elderly Arab population in Wadi Ara, Israel.
Academic Article	BCL11A is a major HbF quantitative trait locus in three different populations with beta-hemoglobinopathies.
Academic Article	Wilson's disease in Israel: a genetic and epidemiological study.
Academic Article	Magnetic resonance imaging traits in siblings discordant for Alzheimer disease.
Academic Article	Essential tremor might be less frequent than Parkinson's disease in North Israel Arab villages.
Academic Article	Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder.
Academic Article	Pro-opiomelanocortin gene variation related to alcohol or drug dependence: evidence and replications across family- and population-based studies.
Academic Article	Association of TTR polymorphisms with hippocampal atrophy in Alzheimer disease families.
Academic Article	Statin use and the risk of Alzheimer's disease: the MIRAGE study.
Academic Article	The Nevada Vital Aging Initiative: a private-public partnership to study early predictors of dementia.
Academic Article	Disclosure of APOE genotype for risk of Alzheimer's disease.
Academic Article	Subtypes of major depression in substance dependence.
Academic Article	Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: a systems biology based approach.
Academic Article	Transient cocaine-associated behavioral symptoms rated with a new instrument, the scale for assessment of positive symptoms for cocaine-induced psychosis (SAPS-CIP).
Academic Article	Homozygote for Huntington disease.
Academic Article	Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations.
Academic Article	Hypertension increases the probability of Alzheimer's disease and of mild cognitive impairment in an Arab community in northern Israel.
Academic Article	Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster.
Academic Article	Education attenuates the effect of medial temporal lobe atrophy on cognitive function in Alzheimer's disease: the MIRAGE study.
Academic Article	Adverse childhood events as risk factors for substance dependence: partial mediation by mood and anxiety disorders.
Academic Article	Molecular genetics of familial Alzheimer's disease.
Academic Article	Familial Alzheimer's disease: progress and problems.
Academic Article	Adolescent cannabis use increases risk for cocaine-induced paranoia.
Academic Article	Molecular genetics of familial Alzheimer's disease.
Academic Article	Assessment and familial aggregation of psychosis in Alzheimer's disease from the National Institute on Aging Late Onset Alzheimer's Disease Family Study.
Academic Article	Confirmation and generalization of an alcohol-dependence locus on chromosome 10q.
Academic Article	Genetic modifiers of Hb E/beta0 thalassemia identified by a two-stage genome-wide association study.
Academic Article	Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration.
Academic Article	Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder.
Academic Article	Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes.
Academic Article	Head circumference, atrophy, and cognition: implications for brain reserve in Alzheimer disease.
Academic Article	Healthy aging and preclinical dementia: the United States-Israel Longitudinal Database project.
Academic Article	Meta-analysis of the association between variants in SORL1 and Alzheimer disease.
Academic Article	Agitated depression in substance dependence.
Academic Article	SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk.
Academic Article	Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans.
Academic Article	Genome-wide analysis of genetic loci associated with Alzheimer disease.
Academic Article	Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.
Academic Article	Mild cognitive impairment is associated with mild parkinsonian signs in a door-to-door study.
Academic Article	Localization and linkage of three polymorphic DNA sequences on human chromosome 20.
Academic Article	Serum paraoxonase activity is associated with variants in the PON gene cluster and risk of Alzheimer disease.
Academic Article	Identification of novel candidate genes for Alzheimer's disease by autozygosity mapping using genome wide SNP data.
Academic Article	An efficient strategy for gene mapping using multipoint linkage analysis: exclusion of the multiple endocrine neoplasia 2A (MEN2A) locus from chromosome 13.
Academic Article	A new human RFLP identified by 7D2 places D13S10 proximal to esterase D.
Academic Article	Linkage analysis of multiple endocrine neoplasia type 2A (MEN-2A) and three DNA markers on chromosome 20: evidence against synteny.
Academic Article	Assignment of multiple endocrine neoplasia type 2A to chromosome 10 by linkage.
Academic Article	One large kindred excludes a locus for multiple endocrine neoplasia type 2A from about 25% of the human autosomal genetic map.
Academic Article	Predictive testing for Huntington's disease with use of a linked DNA marker.
Academic Article	Empirically derived subtypes of opioid use and related behaviors.
Academic Article	Power and pitfalls of the genome-wide association study approach to identify genes for Alzheimer's disease.
Academic Article	Considerations in using linkage analysis as a presymptomatic test for Huntington's disease.
Academic Article	A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression.
Academic Article	5-HTTLPR as a potential moderator of the effects of adverse childhood experiences on risk of antisocial personality disorder.
Academic Article	Ancestry of African Americans with sickle cell disease.
Academic Article	Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence.
Academic Article	No association between ADCYAP1R1 and post-traumatic stress disorder in two independent samples.
Academic Article	GABRG1 and GABRA2 variation associated with alcohol dependence in African Americans.
Academic Article	A CRHR1 haplotype moderates the effect of adverse childhood experiences on lifetime risk of major depressive episode in African-American women.
Academic Article	Influence of ROBO1 and RORA on risk of age-related macular degeneration reveals genetically distinct phenotypes in disease pathophysiology.
Academic Article	Childhood adversity increases risk for nicotine dependence and interacts with a5 nicotinic acetylcholine receptor genotype specifically in males.
Academic Article	Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
Academic Article	Association between polymorphisms in catechol-O-methyltransferase (COMT) and cocaine-induced paranoia in European-American and African-American populations.
Academic Article	Genetics and genomics of late-onset Alzheimer's disease and its endophenotypes.
Academic Article	Magnetic resonance imaging-measured atrophy and its relationship to cognitive functioning in vascular dementia and Alzheimer's disease patients.
Academic Article	Hamilton et al. Respond to "Consolidating Data Harmonization"
Academic Article	The PhenX Toolkit: get the most from your measures.
Academic Article	A genomewide linkage scan of cocaine dependence and major depressive episode in two populations.
Academic Article	A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study.
Academic Article	Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration.
Academic Article	A comprehensive genetic association study of Alzheimer disease in African Americans.
Academic Article	ACSL6 is associated with the number of cigarettes smoked and its expression is altered by chronic nicotine exposure.
Academic Article	Variation in OPRM1 and risk of suicidal behavior in drug-dependent individuals.
Academic Article	High prevalence of mild cognitive impairment and Alzheimer's disease in arabic villages in northern Israel: impact of gender and education.
Academic Article	Collection of clinical and epidemiological data for genetic linkage and association studies.
Academic Article	Eight closely linked loci place the Wilson disease locus within 13q14-q21.
Academic Article	Autosomal linkage scan for loci predisposing to comorbid dependence on multiple substances.
Academic Article	Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases.
Academic Article	Identification of Alzheimer disease-associated variants in genes that regulate retromer function.
Academic Article	Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants.
Academic Article	Serotonin transporter 5-HTTLPR genotype moderates the effects of childhood adversity on posttraumatic stress disorder risk: a replication study.
Academic Article	Improved methods to identify stable, highly heritable subtypes of opioid use and related behaviors.
Academic Article	Genome-wide association study of Alzheimer's disease.
Academic Article	Association of COL25A1 with comorbid antisocial personality disorder and substance dependence.
Academic Article	Linkage analysis followed by association show NRG1 associated with cannabis dependence in African Americans.
Academic Article	ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior.
Academic Article	A functional promoter polymorphism of the d-globin gene is a specific marker of the Arab-Indian haplotype.
Academic Article	Novel late-onset Alzheimer disease loci variants associate with brain gene expression.
Academic Article	Multiple loci influencing hippocampal degeneration identified by genome scan.
Academic Article	Comprehensive search for Alzheimer disease susceptibility loci in the APOE region.
Academic Article	Prevalence of DSM-IV and DSM-5 alcohol, cocaine, opioid, and cannabis use disorders in a largely substance dependent sample.
Academic Article	d-Catenin is genetically and biologically associated with cortical cataract and future Alzheimer-related structural and functional brain changes.
Academic Article	Behavioral variant frontotemporal lobar degeneration with amyotrophic lateral sclerosis with a chromosome 9p21 hexanucleotide repeat.
Academic Article	Prayer at midlife is associated with reduced risk of cognitive decline in Arabic women.
Academic Article	Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
Academic Article	Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci.
Academic Article	Seven new loci associated with age-related macular degeneration.
Academic Article	Fetal hemoglobin in sickle cell anemia: genetic studies of the Arab-Indian haplotype.
Academic Article	GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.
Academic Article	SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.
Academic Article	Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ?4,and the risk of late-onset Alzheimer disease in African Americans.
Academic Article	Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis.
Academic Article	A complex interplay between personality domains, marital status and a variant in CHRNA5 on the risks of cocaine, nicotine dependences and cocaine-induced paranoia.
Academic Article	Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts.
Academic Article	Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment.
Academic Article	Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP).
Academic Article	Identification of functional variants from whole-exome sequencing, combined with neuroimaging genetics.
Academic Article	APOE genotype and MRI markers of cerebrovascular disease: systematic review and meta-analysis.
Academic Article	Locating genetic modifiers for inherited neurodegenerative diseases
Academic Article	Apolipoprotein E genotyping in Alzheimer’s disease
Academic Article	Molecular genetics of autosomal dominant familial Alzheimer's disease
Academic Article	Determining the genetic component of a disease
Academic Article	Alzheimer’s disease and diet
Academic Article	Genetic and environmental risk factors for Alzheimer’s disease in Arabs residing in Israel
Academic Article	The genetic component in Parkinson disease is half that of Alzheimer disease
Academic Article	DNA markers at 13q14-q22 linked to Wilson's disease
Academic Article	Application of database techniques in medical genetics
Academic Article	Alzheimer disease and the fronto-temporal dementias: diseases with cerebral deposition of fibrillar proteins
Academic Article	Letter to the Editor: Suicide and presymptomatic testing in Huntington disease
Academic Article	Book review: Hannah's Heirs: The Quest for the Genetic Origins of Alzheimer's Disease
Academic Article	Age at onset of Alzheimer Disease is influenced by multiple genetic and non-genetic factors: The MIRAGE Study
Academic Article	Effects of smoking, alcohol and APOE genotype on Alzheimer disease: The MIRAGE Study
Academic Article	Genetic neurodegenerative disease models for human aging
Academic Article	Book review: Alzheimer's Disease and the Environment (Royal Society of Medicine Services, Round Table Series, No. 26)
Academic Article	Risk of dementia in first degree relatives of patients with Alzheimer's disease
Academic Article	Linkage map of anonymous loci near the CF gene.
Academic Article	Molecular genetics of familial Alzheimer's disease and its implications
Academic Article	Risk of Alzheimer disease is associated with parental age among apolipoprotein E e4 heterozygotes
Academic Article	Reliability of self-reported age at onset of major depression.
Academic Article	Assessment of genetic risk for Alzheimer's disease among first-degree relatives.
Academic Article	A linkage group of five DNA markers on human chromosome 10.
Academic Article	An anthropometric assessment of Huntington's disease patients and families.
Academic Article	Suicide and attempted suicide in Huntington disease: implications for preclinical testing of persons at risk.
Academic Article	Predictability of phenotype in Huntington's disease.
Academic Article	Diabetes mellitus in Huntington disease.
Academic Article	A genetic model for age at onset in Huntington disease.
Academic Article	Anthropometric discrimination among affected, at-risk, and not-at-risk individuals in families with Huntington disease.
Academic Article	Predicting genotypes at loci for autosomal recessive disorders using linked genetic markers: application to Wilson's disease.
Academic Article	Clinical anthropometry and medical genetics: a compilation of body measurements in genetic and congenital disorders.
Academic Article	Evidence for linkage between Wilson disease and esterase D in three kindreds: detection of linkage for an autosomal recessive disorder by the family study method.
Academic Article	Development of a map of chromosome 11p.
Academic Article	Mapping the Wilson disease locus to a cluster of linked polymorphic markers on chromosome 13.
Academic Article	Managing data for genetic linkage analysis.
Academic Article	Automating data manipulation for genetic analysis using a data base management system.
Academic Article	Assignment of the gene for Wilson disease to chromosome 13: linkage to the esterase D locus.
Academic Article	The natural history of Huntington disease: possible role of "aging genes".
Academic Article	Inverse relationship between age at onset of Huntington disease and paternal age suggests involvement of genetic imprinting.
Academic Article	A test of the hypothesis that age at onset in Huntington disease is controlled by an X-linked recessive modifier.
Academic Article	Does the omission of missing information bias the estimates of age-at-onset distributions?
Academic Article	Segregation analysis in Alzheimer disease: no evidence for a major gene.
Academic Article	Gender equality in Machado-Joseph disease.
Academic Article	Chromosome 13q deletion with Waardenburg syndrome: further evidence for a gene involved in neural crest function on 13q.
Academic Article	[A systematic genetic-epidemiologic family study of patients with Alzheimer disease--experience with the MIRAGE study in Germany].
Academic Article	Multiple etiologies for Alzheimer disease are revealed by segregation analysis.
Academic Article	Linkage of late-onset Alzheimer''s disease with apolipoprotein E type 4 on chromosome 19.
Academic Article	Machado Joseph disease is not an allele of the spinocerebellar ataxia 2 locus.
Academic Article	Interrater agreement for diagnosis of Alzheimer's disease: the MIRAGE study.
Academic Article	Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder.
Academic Article	Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence.
Academic Article	A case of inappropriate apolipoprotein e testing in Alzheimer''s disease due to lack of an informed consent discussion.
Academic Article	Data compatibility in the addiction sciences: an examination of measure commonality.
Academic Article	Association of MAPT haplotypes with Alzheimer''s disease risk and MAPT brain gene expression levels.
Academic Article	F-box/LRR-repeat protein 7 is genetically associated with Alzheimer''s disease.
Academic Article	A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.
Academic Article	Genome-wide association study of the rate of cognitive decline in Alzheimer''s disease.
Academic Article	Deep resequencing of 17 glutamate system genes identifies rare variants in DISC1 and GRIN2B affecting risk of opioid dependence.
Academic Article	Structural interactions between inhibitor and substrate docking sites give insight into mechanisms of human PS1 complexes.
Academic Article	Gene-wide analysis detects two new susceptibility genes for Alzheimer''s disease.
Academic Article	Genetic risk prediction and neurobiological understanding of alcoholism.
Academic Article	Estimating the risk for conversion from mild cognitive impairment to Alzheimer''s disease in an elderly Arab community.
Academic Article	Eye color: A potential indicator of alcohol dependence risk in European Americans.
Academic Article	The ticking clock of Cayo Santiago macaques and its implications for understanding human circadian rhythm disorders.
Academic Article	Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways.
Academic Article	Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer''s disease.
Academic Article	Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.
Academic Article	Follow-up of loci from the International Genomics of Alzheimer''s Disease Project identifies TRIP4 as a novel susceptibility gene.
Academic Article	Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration.
Academic Article	Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.
Academic Article	Evaluating the role of a galanin enhancer genotype on a range of metabolic, depressive and addictive phenotypes.
Academic Article	Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans.
Academic Article	Protective variant for hippocampal atrophy identified by whole exome sequencing.
Academic Article	Ancestry of the Timorese: age-related macular degeneration associated genotype and allele sharing among human populations from throughout the world.
Academic Article	Variations in opioid receptor genes in neonatal abstinence syndrome.
Academic Article	Evidence of CNIH3 involvement in opioid dependence.
Academic Article	Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers.
Academic Article	Search for age-related macular degeneration risk variants in Alzheimer disease genes and pathways.
Academic Article	Missense variant in TREML2 protects against Alzheimer''s disease.
Academic Article	Reply: To PMID 23740775.
Academic Article	The a-endomannosidase gene (MANEA) is associated with panic disorder and social anxiety disorder.
Academic Article	FLT1 genetic variation predisposes to neovascular AMD in ethnically diverse populations and alters systemic FLT1 expression.
Academic Article	Genetic risk prediction and neurobiological understanding of alcoholism.
Academic Article	Genome-wide association meta-analysis of neuropathologic features of Alzheimer''s disease and related dementias.
Academic Article	Rarity of the Alzheimer disease-protective APP A673T variant in the United States.
Academic Article	Convergent genetic and expression data implicate immunity in Alzheimer''s disease.
Academic Article	Which alcohol use disorder criteria contribute to the association of ADH1B with alcohol dependence?
Academic Article	Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease.
Academic Article	Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population-based cohort.
Academic Article	Identification of a rare coding variant in complement 3 associated with age-related macular degeneration.
Academic Article	ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
Academic Article	Nf1 regulates alcohol dependence-associated excessive drinking and gamma-aminobutyric acid release in the central amygdala in mice and is associated with alcohol dependence in humans.
Academic Article	A novel Alzheimer disease locus located near the gene encoding tau protein.
Academic Article	Expanding the genomic roadmap of Alzheimer''s disease.
Academic Article	Genome-wide association study of body mass index in subjects with alcohol dependence.
Academic Article	PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation.
Academic Article	A rare mutation in UNC5C predisposes to late-onset Alzheimer''s disease and increases neuronal cell death.
Academic Article	Global and local ancestry in African-Americans: Implications for Alzheimer''s disease risk.
Academic Article	Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.
Academic Article	Exploring the genetic architecture of alcohol dependence in African-Americans via analysis of a genomewide set of common variants.
Academic Article	Critical evaluation of transcription factor Atf2 as a candidate modulator of alcohol preference in mouse and human populations.
Academic Article	Genome-wide association study of copy number variations (CNVs) with opioid dependence.
Academic Article	Genetic overlap between Alzheimer''s disease and Parkinson''s disease at the MAPT locus.
Academic Article	BCL11A enhancer haplotypes and fetal hemoglobin in sickle cell anemia.
Academic Article	Genomewide Association Study for Maximum Number of Alcoholic Drinks in European Americans and African Americans.
Academic Article	Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error.
Academic Article	Genome-wide Association Study of Cannabis Dependence Severity, Novel Risk Variants, and Shared Genetic Risks.
Academic Article	Assessment of the genetic variance of late-onset Alzheimer''s disease.
Academic Article	Reply: To PMID 25559091.
Academic Article	Further analyses support the association between light eye color and alcohol dependence.
Academic Article	Genetic factor common to schizophrenia and HIV infection is associated with risky sexual behavior: antagonistic vs. synergistic pleiotropic SNPs enriched for distinctly different biological functions.
Academic Article	Two novel loci, COBL and SLC10A2, for Alzheimer''s disease in African Americans.
Academic Article	ABCA7 frameshift deletion associated with Alzheimer disease in African Americans.
Academic Article	Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium.
Academic Article	Homozygosity for a haplotype in the HBG2-OR51B4 region is exclusive to Arab-Indian haplotype sickle cell anemia.
Academic Article	Erratum to: Network-driven plasma proteomics expose molecular changes in the Alzheimer''s brain.
Academic Article	Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer''s disease.
Academic Article	Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence.
Academic Article	Genetic Relationship between Schizophrenia and Nicotine Dependence.
Academic Article	The Interplay Between Risky Sexual Behaviors and Alcohol Dependence: Genome-Wide Association and Neuroimaging Support for LHPP as a Risk Gene.
Academic Article	Association of maternal and infant variants in PNOC and COMT genes with neonatal abstinence syndrome severity.
Academic Article	Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer''s disease.
Academic Article	Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals.
Academic Article	Segregation of a rare TTC3 variant in an extended family with late-onset Alzheimer disease.
Academic Article	A protocadherin gene cluster regulatory variant is associated with nicotine withdrawal and the urge to smoke.
Academic Article	Network-driven plasma proteomics expose molecular changes in the Alzheimer''s brain.
Academic Article	A candidate transacting modulator of fetal hemoglobin gene expression in the Arab-Indian haplotype of sickle cell anemia.
Academic Article	Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms.
Academic Article	S100A10 identified in a genome-wide gene × cannabis dependence interaction analysis of risky sexual behaviours.
Academic Article	Genome-wide association study identifies four novel loci associated with Alzheimer''s endophenotypes and disease modifiers.
Academic Article	Transethnic genome-wide scan identifies novel Alzheimer''s disease loci.
Academic Article	A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer''s Disease Brains.
Academic Article	Genome-wide association study of therapeutic opioid dosing identifies a novel locus upstream of OPRM1.
Academic Article	Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.
Academic Article	Largest GWAS of PTSD (N=20?070) yields genetic overlap with schizophrenia and sex differences in heritability.
Grant	Genetic Basis of Cerebrovascular Mechanisms in Alzheimer’s Disease
Grant	Genetic Epidemiological Studies of Alzheimer Disease
Grant	Centenarian Offspring and Control for Longitudinal Study
Grant	Genetic Factor Underlying Alzheimer Disease
Grant	Family Based Studies of Gene-Environment Interactions in Alzheimer’s Disease
Grant	Mapping of the Alzheimer’s Disease Susceptibility Gene on Chromosome 12
Grant	Biomedical Research Support Program in Genetics
Grant	Multi-Ethnic Genome Wide Alzheimer’s Association
Academic Article	A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer''s disease.
Academic Article	Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer''s disease.
Academic Article	Oxytocin receptor gene polymorphisms, attachment, and PTSD: Results from the National Health and Resilience in Veterans Study.
Academic Article	Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport.
Academic Article	A phased SNP-based classification of sickle cell anemia HBB haplotypes.
Academic Article	Genetics of age-related macular degeneration (AMD).
Academic Article	Genetics of age-related macular degeneration (AMD).
Academic Article	Genome-Wide Association Studies of a Broad Spectrum of Antisocial Behavior.
Academic Article	Caspase-8, association with Alzheimer''s Disease and functional analysis of rare variants.
Academic Article	Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence.
Academic Article	Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors.
Academic Article	Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.
Academic Article	Genome-wide association study identifies a novel locus for cannabis dependence.
Academic Article	Exome Sequencing of Extended Families with Alzheimer''s Disease Identifies Novel Genes Implicated in Cell Immunity and Neuronal Function.
Academic Article	A putative causal relationship between genetically determined female body shape and posttraumatic stress disorder.
Academic Article	The Alzheimer''s Disease Sequencing Project: Study design and sample selection.
Academic Article	Genome-wide association study of Alzheimer''s disease endophenotypes at prediagnosis stages.
Academic Article	Human induced pluripotent stem cells illuminate pathways and novel treatment targets for age-related macular degeneration.
Academic Article	Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer''s disease.
Academic Article	Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated With Opioid Dependence in European Americans.
Academic Article	Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer''s Disease Sequencing Project.
Academic Article	Tau Phosphorylation is Impacted by Rare AKAP9 Mutations Associated with Alzheimer Disease in African Americans.
Academic Article	FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-p Interactions.
Academic Article	One for all and all for One: Improving replication of genetic studies through network diffusion.
Academic Article	Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer''s disease.
Academic Article	Translational studies support a role for serotonin 2B receptor (HTR2B) gene in aggression-related cannabis response.
Academic Article	Analysis of shared heritability in common disorders of the brain.
Academic Article	Genome-wide association meta-analysis of age at first cannabis use.
Award or Honor Receipt	Alfred P. Sloan Research Fellow
Award or Honor Receipt	Who is Who in Science and Engineering (1999 edition)
Award or Honor Receipt	Distinguished Alumnus Award
Award or Honor Receipt	Distinguished Scientist Award
Award or Honor Receipt	Jack Spivack Excellence in Neuroscience Research Award
Academic Article	F131. Genome-Wide Association Study Identifies Glutamate Ionotropic Receptor GRIA4 as a Risk Gene for Comorbid Nicotine Dependence and Major Depression
Academic Article	NOVEL GENETIC VARIANTS ASSOCIATED WITH FAMILIAL LATE-ONSET ALZHEIMER DISEASE IN THE ALZHEIMER’S DISEASE SEQUENCING PROJECT
Academic Article	SEX-SPECIFIC ANALYSIS OF THE ADSP CASE-CONTROL WHOLE-EXOME SEQUENCING DATASET
Academic Article	ALZHEIMER'S DISEASE SEQUENCING PROJECT: CASE-CONTROL ANALYSES
Academic Article	CEREBROSPINAL FLUID ENDOPHENOTYPES PROVIDE INSIGHT INTO BIOLOGY UNDERLYING ALZHEIMER'S DISEASE
Academic Article	BIVARIATE GENOME-WIDE ASSOCIATION STUDY OF NEUROPATHOLOGIC FEATURES OF ALZHEIMER’S DISEASE
Academic Article	GENOME-WIDE RARE VARIANT IMPUTATION AND TISSUE-SPECIFIC TRANSCRIPTOMIC ANALYSIS IDENTIFY NOVEL RARE VARIANT CANDIDATE LOCI IN LATE-ONSET ALZHEIMER’S DISEASE: THE ALZHEIMER’S DISEASE GENETICS CONSORTIUM
Academic Article	GENOME-WIDE ASSOCIATION STUDY OF ALZHEIMER DISEASE ENDOPHENOTYPES AT PRECLINICAL AND MCI STAGES
Academic Article	Genome-Wide Association Study Identifies HTR2B as a Risk Variant of Cannabis-Related Aggression in African Americans
Academic Article	FURTHER STRATIFICATION OF APOE E4-NEGATIVE SUBJECTS IDENTIFIES NOVEL GENES FOR ALZHEIMER'S DISEASE
Academic Article	HIGH-RESOLUTION IMPUTATION IN GENOME-WIDE ASSOCIATION STUDIES OF LATE-ONSET ALZHEIMER'S DISEASE IDENTIFIES NOVEL RARE VARIANT ASSOCIATIONS
Academic Article	A COMMON ALLELE IN SPI1 LOWERS RISK AND DELAYS AGE AT ONSET FOR ALZHEIMER'S DISEASE
Academic Article	ALZHEIMER'S DISEASE SEQUENCING PROJECT: SEARCH FOR ALZHEIMER'S DISEASE RESILIENCE GENES THAT MAY MODIFY DISEASE SUSCEPTIBILITY IN SPECIFIC APOE GENOTYPE BACKGROUNDS
Academic Article	RARE DELETERIOUS AND LOSS-OF-FUNCTION VARIANTS IN OPRL1 AND GAS2L2 CONTRIBUTE TO THE RISK OF LATE-ONSET ALZHEIMER’S DISEASE: ALZHEIMER’S DISEASE SEQUENCING PROJECT CASE-CONTROL STUDY
Academic Article	IDENTIFICATION OF NOVEL CANDIDATE GENES FOR EARLY-ONSET ALZHEIMER'S DISEASE THROUGH INTEGRATED WHOLE-EXOME SEQUENCING AND EXOME CHIP ARRAY ASSOCIATION ANALYSIS
Academic Article	Exome array analysis identifies novel risk variants for Alzheimer's disease with onset before 65 years
Academic Article	LOW-FREQUENCY VARIANT IMPUTATION IDENTIFIES NOVEL DISEASE-ASSOCIATED LOCI IN A GENOME-WIDE ASSOCIATION STUDY OF LATE-ONSET ALZHEIMER'S DISEASE
Academic Article	WHOLE-EXOME SEQUENCING OF HISPANIC EARLY-ONSET ALZHEIMER DISEASE FAMILIES IDENTIFIES RARE VARIANTS IN MULTIPLE ALZHEIMER'S-RELATED GENES
Academic Article	A VARIANT IN STK24 ACHIEVES GENOME-WIDE SIGNIFICANCE IN AFRICAN AMERICANS USING A LIABILITY MODEL
Academic Article	Ttn as a likely causal gene for QTL of alcohol preference on mouse chromosome 2
Academic Article	Genome-wide association study in different clinical stages of Alzheimer’s disease
Academic Article	Analyzing pathway specificity of variants associated with Alzheimer’s disease from the scientific literature corpus
Academic Article	Speaker 4: Joel Gelernter, USA
Academic Article	PM296. SORCS2 regulates alcohol withdrawal severity and excitatory synaptic transmission
Academic Article	STRUCTURAL VARIATION (SV) IN HETEROGENOUS WHOLE-GENOME SEQUENCING DATA FROM 111 FAMILIES AT RISK FOR ALZHEIMER'S DISEASE: ALZHEIMER'S DISEASE SEQUENCING PROJECT SV STUDY
Academic Article	Transethnic genome-wide meta-analysis for Alzheimer disease
Academic Article	MULTIVARIATE PHENOTYPES ASSOCIATION STUDY OF NEUROPATHOLOGICAL FEATURES OF ALZHEIMER'S DISEASE AND RELATED DEMENTIAS
Academic Article	Low-frequency variant imputation identifies rare variant candidate loci in a gwas of late-onset Alzheimer’s disease in the igap consortium
Academic Article	ABCA7 deletion associated with Alzheimer's disease in African Americans
Academic Article	The role of common and rare variants in risk for Alzheimer's disease across populations
Academic Article	Genome-wide association study identifies susceptibility loci associated with the rate of cognitive decline
Academic Article	Protective variant for rate of hippocampal volume loss identified by whole exome sequencing in APOE-e3e3 males with MCI
Academic Article	Genetic variation in PLXNA4 associated with susceptibility of Alzheimer’s disease through tau phosphorylation
Academic Article	Genome-wide association analyses of onset age in late-onset Alzheimer disease (LOAD) demonstrate no strong effect outside of the APOE region
Academic Article	Candidate gene study in the endosome-to-Golgi retrieval pathway reveals association of retromer genes with Alzheimer's disease
Academic Article	Genetic association of variants with late-onset Alzheimer's disease risk and brain gene expression
Academic Article	ALCOHOL DEPENDENCE GWAS IN TWO POPULATIONS WITH CONSIDERATION OF SUICIDE-RELATED TRAITS
Academic Article	LINKAGE AND ASSOCIATION STUDIES OF CANNABIS DEPENDENCE SUGGEST NRG1 AS A RISK LOCUS
Academic Article	Two rare AKAP9 variants are associated with Alzheimers disease in African Americans
Academic Article	ADGC+: An expanded Alzheimer's Disease Genetics Consortium (ADGC) genome-wide association study
Academic Article	The identification of rare variants in late-onset Alzheimer’s disease using extended families
Academic Article	Late-onset Alzheimer’s disease neuropathology genomic screen identifies novel loci for neuritic plaque and other Alzheimer’s neuropathology features
Academic Article	A review of published genetic studies using ADNI multimodality quantitative phenotypes: MRI, PET, fluid biomarkers, cognition and clinical status
Academic Article	Genome-wide association study for cognitive decline
Academic Article	Correction: ACSL6 Is Associated with the Number of Cigarettes Smoked and Its Expression Is Altered by Chronic Nicotine Exposure
Academic Article	Association of TREM2 variants with Alzheimer's disease in African-Americans: For the Alzheimer's Disease Genetics Consortium (ADGC)
Academic Article	APP associated with late-onset Alzheimer's disease in an autopsy-confirmed dataset
Academic Article	Structural, functional and molecular imaging as intermediate phenotypes for studies of candidate genes, pathways and GWAS in Alzheimer's disease
Academic Article	A rare mutation in the CTNND2 gene is associated with increased Aß42 secretion
Academic Article	Genome-wide association study of Alzheimer's-related brain MRI traits identifies several loci influencing degeneration of the hippocampus
Academic Article	CTNNA3, CAPRIN2 and SPG20 are significantly associated with Alzheimer's disease in preliminary analyses of a genome-wide association study in African-Americans
Academic Article	Intracellular Traffic and Neurodegenerative Disorders
Academic Article	Clustering Based on Genetic Ancestry
Academic Article	Mild Parkinsonian Signs (MPS) Are Associated with Mild Cognitive Impairment (MCI) but Not Predictive of Progression to Alzheimer's Disease (AD) in a Door-to-Door Study of an Elderly Arab Population
Academic Article	U.S. Alzheimer's Disease Genetics Consortium: Organization and results
Academic Article	Genome-wide Association of Cerebrovascular and Neurodegenerative Quantitative MRI Traits in Alzheimer's Disease
Academic Article	GENETIC MODERATION OF ADVERSE CHILDHOOD EVENTS AND RISK OF DEPRESSION AND SUBSTANCE DEPENDENCE
Academic Article	GENOMEWIDE STUDIES OF ALCOHOL DEPENDENCE
Academic Article	Comparison of Family Based Methods For Genome-Wide Association Study In the Framingham Eye Study
Academic Article	A Genomewide Association Study Of Plasma Total IGE In The Framingham Heart Study Identifies HLA-A As A Susceptibility Locus
Academic Article	Identification of Gene-Gene Interactions in Alzheimer Disease Using CoOperative Game Theory
Academic Article	Genome-Wide Scan Suggested Novel Alzheimer’s Disease Susceptibility Genes by Factoring Influence of APOE
Academic Article	The ADGC genome browser
Academic Article	Genetic Associations between VPS10 Receptor Genes and Late-Onset Alzheimer's Disease
Academic Article	The genetics of Alzheimer's disease
Academic Article	Using CSF biomarkers to replicate genetic associations in Alzheimer's disease.
Academic Article	Statin use is associated with reduced risk of Alzheimer's disease
Academic Article	Polymorphism in the cyclooxygenase-2 (COX-2) and presenilin 2 (PS2) gene promoters: Impact on inflammatory signaling and potential contribution to the etiopathology of Alzheimer's disease (AD)
Academic Article	Genetic polymorphisms associated with fetal hemoglobin response to hydroxyurea in patients with sickle cell anemia
Academic Article	Recent findings from a genomewide linkage scan for cocaine dependence
Academic Article	Polymorphisms in paraoxonase genes PON1, PON2 and PON3 are associated with late onset Alzheimer disease
Academic Article	Modeling genetic polymorhphisms and sickle cell associated vasoocclusive events using classification and regression trees (CART)
Academic Article	Polymorphisms (Snps) in multiple genes of the Tgf-beta/Bmp pathway are associated with a global measure of sickle cell disease severity
Academic Article	Modeling Genetic Polymorphisms and Sickle Cell Associated Vasoocclusive Events Using Classification and Regression Trees (CART) and Stochastic Gradient Boosting (SGB)
Academic Article	P2-060: Comparison of Alzheimer and vascular dementia patients using MRI-based measures of atrophy
Academic Article	Adherence in Internet interventions for anxiety and depression: Systematic review
Academic Article	CLONING THE WILSON DISEASE GENE
Academic Article	219Cross-national comparison of risk factors for Alzheimer's disease: Same genetic risk in different environments?
Academic Article	The use of consanguineous families from isolated populations to identify genes for recessive, non-syndromal deafness
Academic Article	Localization of a gene for blood pressure regulation to human chromosome 18q
Academic Article	Candidate genes associated with Alzheimer's disease
Academic Article	Analysis of candidate genes of chromosome 12P
Academic Article	A genetic linkage study on late-onset familial Alzheimer's disease does not provide strong evidence for linkage to chromosome 1Q22, 9Q21.1, 10Q23, and chromosome 11Q23.3
Academic Article	Does hypertension affect the risk and age at onset of Alzheimer disease?
Academic Article	Genetic linkage studies of Alzheimer's disease in Israeli arabs
Academic Article	The REVEAL study: A new model for susceptibility genotyping. risk assessment and counseling for Alzheimer's disease
Academic Article	Preliminary findings from the REVEAL Study: Genetic risk assessment and counseling for Alzheimer's disease
Academic Article	Authors' response to commentaries
Academic Article	Response to Kessler: Suicide and presymptomatic testing in Huntington disease
Academic Article	SEARCHING FOR DISEASE MODIFIER GENES IN ß0THALASSEMIA/Hb E
Academic Article	A fine structure linkage map for chromosome 13
Academic Article	Fetal Hemoglobin In Sickle Cell Anemia: Molecular Characterization of Saudi Patients From the Eastern Province
Academic Article	Whole exome sequencing study identifies novel rare and common Alzheimer''s-Associated variants involved in immune response and transcriptional regulation.
Academic Article	Genome-wide association study of cognitive flexibility assessed by the Wisconsin Card Sorting Test.
Academic Article	Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer''s disease.
Academic Article	Targeted Sequencing of Alzheimer Disease Genes in African Americans Implicates Novel Risk Variants.
Academic Article	Risk Locus Identification Ties Alcohol Withdrawal Symptoms to SORCS2.
Academic Article	Genome-wide association study identifies glutamate ionotropic receptor GRIA4 as a risk gene for comorbid nicotine dependence and major depression.
Academic Article	An efficient analytic approach in genome-wide identification of methylation quantitative trait loci response to fenofibrate treatment.
Academic Article	Variation in TMEM106B in chronic traumatic encephalopathy.
Academic Article	Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer''s disease.
Academic Article	Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.
Academic Article	Ancestral origin of ApoE e4 Alzheimer disease risk in Puerto Rican and African American populations.
Academic Article	A rare missense variant of CASP7 is associated with familial late-onset Alzheimer''s disease.
Academic Article	Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease.
Academic Article	Comparison of methods for multivariate gene-based association tests for complex diseases using common variants.
Academic Article	The genetics and epigenetics of Neonatal Abstinence Syndrome.
Academic Article	Genetic meta-analysis of diagnosed Alzheimer''s disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing.
Academic Article	The Utah Protocol for Postmortem Eye Phenotyping and Molecular Biochemical Analysis.
Academic Article	Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry.
Academic Article	Salivary microRNAs identified by small RNA sequencing and machine learning as potential biomarkers of alcohol dependence.
Academic Article	CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.
Academic Article	Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype.
Academic Article	Genome-Wide Meta-Analyses of FTND and TTFC Phenotypes.
Academic Article	A systems biology approach towards understanding and treating non-neovascular age-related macular degeneration.
Academic Article	Author Correction: Genetic meta-analysis of diagnosed Alzheimer''s disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing.
Award or Honor Receipt	BU Evans Center for Interdisciplinary Biomedical Research Leadership Award
Academic Article	APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE e4 on Alzheimer''s Disease Risk in a Multiracial Sample.
Academic Article	International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci.
Academic Article	Correction: Whole exome sequencing study identifies novel rare and common Alzheimer''s-Associated variants involved in immune response and transcriptional regulation.
Academic Article	A regulatory variant of CHRM3 is associated with cannabis-induced hallucinations in European Americans.
Academic Article	Post-GWAS analysis of six substance use traits improves the identification and functional interpretation of genetic risk loci.
Academic Article	Genome-Wide Association Study of Opioid Cessation.
Academic Article	Exceptionally low likelihood of Alzheimer''s dementia in APOE2 homozygotes from a 5,000-person neuropathological study.
Academic Article	Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies.
Academic Article	Genomic influences on self-reported childhood maltreatment.
Academic Article	Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium.
Academic Article	Prefrontal cortex eQTLs/mQTLs enriched in genetic variants associated with alcohol use disorder and other diseases.
Academic Article	Association of OPRM1 Functional Coding Variant With Opioid Use Disorder: A Genome-Wide Association Study.
Academic Article	Sex-dependent autosomal effects on clinical progression of Alzheimer''s disease.
Academic Article	Genome-wide association study of rate of cognitive decline in Alzheimer''s disease patients identifies novel genes and pathways.
Academic Article	Genetic variants and functional pathways associated with resilience to Alzheimer''s disease.
Academic Article	Analysis of brain region-specific co-expression networks reveals clustering of established and novel genes associated with Alzheimer disease.
Academic Article	Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.
Academic Article	A large-scale genome-wide association study meta-analysis of cannabis use disorder.
Grant	The Alzheimer Disease Sequencing Analysis Collaborative
Grant	Precision Monitoring and Assessment in the Framingham Study: Cognitive, MRI, Genetic and Biomarker Precursors of AD & Dementia
Grant	Alzheimer Disease Genetic Architecture in African Americans
Grant	International Alzheimer's Disease Genetics Consortium
Grant	Alzheimer's Disease Genetics Consortium
Grant	Coordinating Center for Genetics and Genomics of Alzheimer's Disease
Grant	Alzheimer's Disease Genetics Consortium
Grant	Genetic Studies of Alzheimer Disease in Koreans
Grant	Metabolomic Signatures for Disease Sub-classification and Target Prioritization in AMP-AD
Grant	Institutional Program Unifying Population and Laboratory Based Sciences Award
Grant	Genomic and Biological Studies of APOE e2 in Alzheimer's Disease
Grant	Genetic Mechanisms Shared by Eye and Brain Diseases as Novel Therapeutic Targets for Age-Related macular Degeneration
Grant	Alzheimer Disease Genetic Architecture in African Americans
Grant	Personnel Agreement for Research Services of Mark Logue
Grant	Coordinating Center for Genetics and Genomics of Alzheimer's Disease
Grant	Identifying Methamphetamine Risk Variants by Extreme Phenotype Exome Sequencing
Grant	Consortium for Alzheimer Sequencing and Analysis (CASA)
Grant	Alzheimer Disease Genetics Consortium
Academic Article	Analysis of telomere length variation and Shelterin complex subunit gene expression changes in ethanol-exposed human embryonic stem cells.
Academic Article	Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits.

Highlights

Search Criteria

Alzheimer
s
disease