Search Results to George T. O'Connor, MD

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Research Expertise & Professional Interests My research focuses on epidemiology, including genetic epidemiology, and clinical investigations of asthma, allergy, chronic obstructive pulmonary disease, and sleep apnea. I have been the Boston University / Boston Medical Center principal investigator of multiple NIH-funded multi-center investigations, currently including the Inner-City Asthma Consortium (ICAC), the Vitamin D Antenatal Asthma Reduction Trial (VDAART), and the All of Us Research Program. Our ICAC studies include clinical trials in children and adolescents with asthma and a birth-cohort study examining the risk factors for asthma and allergy in the inner city. I also conduct epidemiologic and genetic epidemiologic research at the Framingham Heart Study, including genome-wide association studies seeking novel genetic determinants of lung function impairment, interstitial lung abnormalities, and atopy. I have collaborated with the Division of Computational Biomedicine's studies of alterations in gene expression related to tobacco smoking and COPD. My research spans disciplines including adult medicine, pediatrics, obstetrics, epidemiology, genetics and genomics, immunology, and environmental science. At Boston Medical Center, my outpatient practice focuses on adults with asthma, COPD, and bronchiectasis. I am an Associate Editor of JAMA.
Self-Described Keywords COPD

One or more keywords matched the following items that are connected to O'Connor, George

Item TypeName
Concept Pulmonary Disease, Chronic Obstructive
Academic Article Environmental and genetic risk factors and gene-environment interactions in the pathogenesis of chronic obstructive lung disease.
Academic Article Heritability of longitudinal change in lung function. The Framingham study.
Academic Article Sleep and sleep-disordered breathing in adults with predominantly mild obstructive airway disease.
Academic Article Association between glycemic state and lung function: the Framingham Heart Study.
Academic Article Genetic loci influencing lung function: a genome-wide scan in the Framingham Study.
Academic Article Association of physical activity with sleep-disordered breathing.
Academic Article Framingham Heart Study genome-wide association: results for pulmonary function measures.
Academic Article Systemic inflammation and COPD: the Framingham Heart Study.
Academic Article A genome-wide association study of pulmonary function measures in the Framingham Heart Study.
Academic Article The role of allergy and nonspecific airway hyperresponsiveness in the pathogenesis of chronic obstructive pulmonary disease.
Academic Article Eosinophil and T cell markers predict functional decline in COPD patients.
Academic Article The relation of airways responsiveness and atopy to the development of chronic obstructive lung disease.
Academic Article Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.
Academic Article A multidimensional computer adaptive test approach to dyspnea assessment.
Academic Article Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.
Academic Article Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD.
Academic Article A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment.
Academic Article Adhesion molecules, endothelin-1 and lung function in seven population-based cohorts.
Academic Article Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
Academic Article Elastin and collagen degradation products in urine of smokers with and without chronic obstructive pulmonary disease.
Academic Article APOM and high-density lipoprotein cholesterol are associated with lung function and per cent emphysema.
Academic Article Screening, Case-Finding, and Outcomes for Adults With Unrecognized COPD.
Academic Article Sex-Based Genetic Association Study Identifies CELSR1 as a Possible Chronic Obstructive Pulmonary Disease Risk Locus among Women.
Academic Article A comparison of visual and quantitative methods to identify interstitial lung abnormalities.
Academic Article Association Between Interstitial Lung Abnormalities and All-Cause Mortality.
Academic Article Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1.
Academic Article Molecular mechanisms underlying variations in lung function: a systems genetics analysis.
Academic Article Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.
Grant Effects of 12 Week Treatment of 5 25 or &5 Mg BIIL 284 BS on Exercise Endurance in Patients with Chronic Obstructive Pulmonary Disease Double Blind Double Dummy Placebo Controlled Randomized Parallel Group Dose Ranging Study
Academic Article Heritability and genome-wide association study of diffusing capacity of the lung.
Academic Article Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.
Academic Article Albuminuria, Lung Function Decline, and Risk of Incident Chronic Obstructive Pulmonary Disease. The NHLBI Pooled Cohorts Study.
Academic Article Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.
Academic Article Discriminative Accuracy of FEV1:FVC Thresholds for COPD-Related Hospitalization and Mortality.
Academic Article Radiographic pulmonary vessel volume, lung function and airways disease in the Framingham Heart Study.
Grant ScreenFlow - COPD Screening System
Grant ScreenFlow - COPD Screening System
Academic Article Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants.

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  • COPD