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Search Results to James A. Hamilton, PhD

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Research Expertise & Professional Interests Research in our group is aimed at providing fundamental information relating to heart disease, diabetes, obesity, and diseases related to fatty acid metabolism. An overall goal to is to develop novel approaches to biomedical issues by integrating physical-chemical and physiological/biochemical approaches. In our newer research this is achieved by assembling multi-disciplinary teams to translate basic research into clinical applications. We use physical and instrumental methods (including solution state 13C NMR spectroscopy, solid state and magic angle spinning multinuclear NMR, multidimensional NMR, MR imaging, and fluorescence) that are tailored to the specific questions we are addressing. These techniques are complemented with molecular modeling, molecular biology and other cell biology methods.

One or more keywords matched the following items that are connected to Hamilton, James

Item TypeName
Concept Electron Spin Resonance Spectroscopy
Concept Models, Structural
Concept Magnetic Resonance Spectroscopy
Concept Spectrum Analysis
Concept Computational Biology
Academic Article Temperature-dependent molecular motions of cholesterol esters: a carbon-13 nuclear magnetic resonance study.
Academic Article Solubilization and localization of cholesteryl oleate in egg phosphatidylcholine vesicles. A carbon 13 NMR study.
Academic Article Phase behavior and crystalline structures of cholesteryl ester mixtures: a C-13 MASNMR study.
Academic Article Interactions of a very long chain fatty acid with model membranes and serum albumin. Implications for the pathogenesis of adrenoleukodystrophy.
Academic Article Molecular organization and motions of crystalline monoacylglycerols and diacylglycerols: a C-13 MASNMR study.
Academic Article Structural requirements for charged lipid molecules to directly increase or suppress K+ channel activity in smooth muscle cells. Effects of fatty acids, lysophosphatidate, acyl coenzyme A and sphingosine.
Academic Article Molecular organization and motions of cholesteryl esters in crystalline and liquid crystalline phases: a 13C and 1H magic angle spinning NMR study.
Academic Article Conformation and inhibitory properties of peptides based on the tissue kallikrein-aprotinin complex.
Academic Article Profound increase in viscosity and aggregation of pig gastric mucin at low pH.
Academic Article NMR studies of phospholipase C hydrolysis of phosphatidylcholine in model membranes.
Academic Article Interactions of acyl-coenzyme A with phosphatidylcholine bilayers and serum albumin.
Academic Article Binding of ethyl oleate to low density lipoprotein, phospholipid vesicles, and albumin: a 13C NMR study.
Academic Article 13C MAS NMR studies of crystalline cholesterol and lipid mixtures modeling atherosclerotic plaques.
Academic Article Solution structure of human intestinal fatty acid binding protein: implications for ligand entry and exit.
Academic Article Magic-angle spinning and solution 13C nuclear magnetic resonance studies of medium- and long-chain cholesteryl esters in model bilayers.
Academic Article Monoacylglycerols alter the lipid composition and molecular mobility of phosphatidylcholine bilayers: 13C NMR evidence of dynamic lipid remodeling.
Academic Article Incorporation of medium chain triacylglycerols into phospholipid bilayers: effect of long chain triacylglycerols, cholesterol, and cholesteryl esters.
Academic Article Locations of the three primary binding sites for long-chain fatty acids on bovine serum albumin.
Academic Article Solubilization and localization of weakly polar lipids in unsonicated egg phosphatidylcholine: A 13C MAS NMR study.
Academic Article Identification of different lipid phases and calcium phosphate deposits in human carotid artery plaques by MAS NMR spectroscopy.
Academic Article High-field 13C NMR Studies of certain normal and abnormal human plasma lipoproteins.
Academic Article A comparative study of the backbone dynamics of two closely related lipid binding proteins: bovine heart fatty acid binding protein and porcine ileal lipid binding protein.
Academic Article Incorporation of [1-13C]oleate into cellular triglycerides in differentiating 3T3L1 cells.
Academic Article Solution structure of ileal lipid binding protein in complex with glycocholate.
Academic Article Quantification in situ of crystalline cholesterol and calcium phosphate hydroxyapatite in human atherosclerotic plaques by solid-state magic angle spinning NMR.
Academic Article Carbon-13 nuclear magnetic resonance studies of cholesteryl esters and cholesteryl ester/triglyceride mixtures.
Academic Article Natural abundance 13C nuclear magnetic resonance studies of human plasma high density lipoproteins.
Academic Article Molecular dynamics of lipids in human plasma high density lipoproteins. A high field 13C NMR study.
Academic Article Quantification of cholesteryl esters in human and rabbit atherosclerotic plaques by magic-angle spinning (13)C-NMR.
Academic Article Transthyretin: a review from a structural perspective.
Academic Article Interactions of very long-chain saturated fatty acids with serum albumin.
Academic Article A solid-state NMR study of phospholipid-cholesterol interactions: sphingomyelin-cholesterol binary systems.
Academic Article Interactions of acyl carnitines with model membranes: a (13)C-NMR study.
Academic Article Lipid dynamics in human low density lipoproteins and human aortic tissue with fibrous plaques. A study by high field 13C NMR spectroscopy.
Academic Article NMR assignment and structural characterization of the fatty acid binding protein from the flight muscle of Locusta migratoria.
Academic Article Sulfonylureas rapidly cross phospholipid bilayer membranes by a free-diffusion mechanism.
Academic Article Fatty acid interactions with proteins: what X-ray crystal and NMR solution structures tell us.
Academic Article Identification of cholesteryl esters in human carotid atherosclerosis by ex vivo image-guided proton MRS.
Academic Article Locating high-affinity fatty acid-binding sites on albumin by x-ray crystallography and NMR spectroscopy.
Academic Article The interfacial conformation and transbilayer movement of diacylglycerols in phospholipid bilayers.
Academic Article Identification of atherosclerotic lipid deposits by diffusion-weighted imaging.
Academic Article Interactions between fatty acids and alpha-synuclein.
Academic Article Targeted binding of PLA microparticles with lipid-PEG-tethered ligands.
Academic Article Medium-chain versus long-chain triacylglycerol emulsion hydrolysis by lipoprotein lipase and hepatic lipase: implications for the mechanisms of lipase action.
Academic Article The distribution of oleic acid between chylomicron-like emulsions, phospholipid bilayers, and serum albumin. A model for fatty acid distribution between lipoproteins, membranes, and albumin.
Academic Article Insider access: pepducin symposium explores a new approach to GPCR modulation.
Academic Article Medium-chain fatty acid binding to albumin and transfer to phospholipid bilayers.
Academic Article Interactions of triglycerides with phospholipids: incorporation into the bilayer structure and formation of emulsions.
Academic Article Study of the miscibility of cholesteryl oleate in a matrix of ceramide, cholesterol and fatty acid.
Academic Article Ionization and phase behavior of fatty acids in water: application of the Gibbs phase rule.
Academic Article Hydrolysis of a phospholipid in an inert lipid matrix by phospholipase A2: a 13C NMR study.
Academic Article The ionization and distribution behavior of oleic acid in chylomicrons and chylomicron-like emulsion particles and the influence of serum albumin.
Academic Article Interactions of oleic acid with liver fatty acid binding protein: a carbon-13 NMR study.
Academic Article Temperature-dependent molecular motions and phase behavior of cholesteryl ester analogues.
Academic Article Transfer of oleic acid between albumin and phospholipid vesicles.
Academic Article Carbon 13 NMR studies of saturated fatty acids bound to bovine serum albumin. I. The filling of individual fatty acid binding sites.
Academic Article Carbon 13 NMR studies of saturated fatty acids bound to bovine serum albumin. II. Electrostatic interactions in individual fatty acid binding sites.
Academic Article Partial synthesis and properties of a series of N-acyl sphingomyelins.
Academic Article Nuclear magnetic resonance studies of lipoproteins.
Academic Article Natural abundance carbon-13 nuclear magnetic resonance spectra of human serum lipoproteins.
Academic Article Thermotropic properties and molecular dynamics of cholesteryl ester rich very low density lipoproteins: effect of hydrophobic core on polar surface.
Academic Article The ionization behavior of fatty acids and bile acids in micelles and membranes.
Academic Article Interactions of myristic acid with bovine serum albumin: a 13C NMR study.
Academic Article Transbilayer movement of bile acids in model membranes.
Academic Article The ionization behavior of bile acids in different aqueous environments.
Academic Article The effect of free cholesterol on the solubilization of cholesteryl oleate in phosphatidylcholine bilayers: A 13C-NMR study.
Academic Article Molecular motions and thermotropic phase behavior of cholesteryl esters with triolein.
Academic Article Natural abundance carbon-13 nuclear magnetic resonance spectra of the canine sciatic nerve.
Academic Article Solubilization of triolein and cholesteryl oleate in egg phosphatidylcholine vesicles.
Academic Article Solubilization and localization of triolein in phosphatidylcholine bilayers: a 13C NMR study.
Academic Article Interfacial conformation of dipalmitoylglycerol and dipalmitoylphosphatidylcholine in phospholipid bilayers.
Academic Article 1H NMR studies of lymph chylomicra and very low density lipoproteins from nonhuman primates.
Academic Article Interactions of the carboxyl group of oleic acid with bovine serum albumin: a 13C NMR study.
Academic Article Physical studies of d less than 1.006 g/ml lymph lipoproteins from rats fed palmitate-rich diets.
Academic Article Ionization behavior of aqueous short-chain carboxylic acids: a carbon-13 NMR study.
Academic Article Lipoprotein-X: carbon-13 nuclear magnetic resonance studies on native, reconstituted, and model systems.
Academic Article A multinuclear solid-state NMR study of phospholipid-cholesterol interactions. Dipalmitoylphosphatidylcholine-cholesterol binary system.
Academic Article Interactions of lyso 1-palmitoylphosphatidylcholine with phospholipids: a 13C and 31P NMR study.
Academic Article 13C NMR studies of the binding of medium-chain fatty acids to human serum albumin.
Academic Article [Structure of plasma lipoproteins (author's transl)].
Academic Article Influence of muscle fiber type composition on early fat accumulation under high-fat diet challenge.
Academic Article MRI of atherosclerosis and fatty liver disease in cholesterol fed rabbits.
Academic Article Arteriosclerosis, Thrombosis, and Vascular Biology

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  • structural
  • biology
  • spectroscopy