Connection

Search Results to Alpaslan Dedeoglu, MD, PhD

This is a "connection" page, showing the details of why an item matched the keywords from your search.

                     
                     

One or more keywords matched the following properties of Dedeoglu, Alpaslan

PropertyValue
Research Expertise & Professional Interests Dr. Alpaslan Dedeoglu received his MD from the Istanbul University School of Medicine and completed a pharmacology program at the Marmara University in 1992. During and after his pharmacology program he worked at the University of Arizona, Ohio State University, and Massachusetts General Hospital; he then joined Boston University in 2000. Dr. Dedeoglu’s major research interests are neuroanatomy, neuropathology, and the neurochemistry of animal models of neurodegenerative disorders. His labs are located at the Boston VA Medical Center. Dr. Dedeoglu is the PI of several ongoing projects that are funded by the NIH, VA, and private foundations. He also works with therapeutic trials in rodent models of neurodegenerative disorders.

One or more keywords matched the following items that are connected to Dedeoglu, Alpaslan

Item TypeName
Concept Acute Disease
Concept Alzheimer Disease
Concept Amyotrophic Lateral Sclerosis
Concept Central Nervous System Stimulants
Concept Anti-Inflammatory Agents, Non-Steroidal
Concept Base Sequence
Concept Cell Survival
Concept Chronic Disease
Concept Corpus Striatum
Concept Disease Models, Animal
Concept Drug Synergism
Concept Huntington Disease
Concept Longitudinal Studies
Concept Mice, Inbred Strains
Concept Motor Skills
Concept Myelin Sheath
Concept Magnetic Resonance Spectroscopy
Concept Organ Size
Concept Parkinson Disease, Secondary
Concept Psychiatric Status Rating Scales
Concept Repetitive Sequences, Nucleic Acid
Concept Somatosensory Cortex
Concept Somatostatin
Concept Spectrum Analysis
Concept Spinal Cord
Concept Stress, Psychological
Concept Succinate Dehydrogenase
Concept Sulfonamides
Concept Superoxide Dismutase
Concept Survival
Concept Synapses
Concept Hazardous Substances
Concept Signal Transduction
Concept Gene Library
Concept Survival Rate
Concept Free Radical Scavengers
Concept Sp1 Transcription Factor
Concept Motor Neuron Disease
Concept Rats, Sprague-Dawley
Concept Protein Structure, Tertiary
Concept Oxidative Stress
Concept Disease Progression
Concept HSP70 Heat-Shock Proteins
Concept Persian Gulf Syndrome
Concept Transgenes
Concept GTP-Binding Protein alpha Subunits, Gs
Concept Dietary Supplements
Concept Neurodegenerative Diseases
Concept Succinic Acid
Concept Genetic Predisposition to Disease
Concept Salicylic Acid
Concept Neurotoxicity Syndromes
Concept Two-Hybrid System Techniques
Concept Amino Acid Transport System X-AG
Concept Dendritic Spines
Concept Serotonin Plasma Membrane Transport Proteins
Concept STAT1 Transcription Factor
Concept Amyloid Precursor Protein Secretases
Concept Neural Stem Cells
Academic Article Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.
Academic Article Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease.
Academic Article N-acetyl-L-cysteine improves survival and preserves motor performance in an animal model of familial amyotrophic lateral sclerosis.
Academic Article Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation.
Academic Article Creatine increase survival and delays motor symptoms in a transgenic animal model of Huntington's disease.
Academic Article Dichloroacetate exerts therapeutic effects in transgenic mouse models of Huntington's disease.
Academic Article Malonate and 3-nitropropionic acid neurotoxicity are reduced in transgenic mice expressing a caspase-1 dominant-negative mutant.
Academic Article Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP.
Academic Article Transgenic ALS mice show increased vulnerability to the mitochondrial toxins MPTP and 3-nitropropionic acid.
Academic Article Effects of an inhibitor of poly(ADP-ribose) polymerase, desmethylselegiline, trientine, and lipoic acid in transgenic ALS mice.
Academic Article Therapeutic efficacy of EGb761 (Gingko biloba extract) in a transgenic mouse model of amyotrophic lateral sclerosis.
Academic Article Lipoic acid improves survival in transgenic mouse models of Huntington's disease.
Academic Article Increased oxidative damage to DNA in a transgenic mouse model of Huntington's disease.
Academic Article Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease.
Academic Article Reduced creatine kinase activity in transgenic amyotrophic lateral sclerosis mice.
Academic Article Therapeutic effects of cystamine in a murine model of Huntington's disease.
Academic Article Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway.
Academic Article Mice overexpressing 70-kDa heat shock protein show increased resistance to malonate and 3-nitropropionic acid.
Academic Article Cytochrome C and caspase-9 expression in Huntington's disease.
Academic Article Huntington's disease of the endocrine pancreas: insulin deficiency and diabetes mellitus due to impaired insulin gene expression.
Academic Article Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease.
Academic Article Creatine therapy provides neuroprotection after onset of clinical symptoms in Huntington's disease transgenic mice.
Academic Article Magnetic resonance spectroscopic analysis of Alzheimer's disease mouse brain that express mutant human APP shows altered neurochemical profile.
Academic Article 3-Nitropropionic acid-induced neurotoxicity--assessed by ultra high resolution positron emission tomography with comparison to magnetic resonance spectroscopy.
Academic Article Effects of CAG repeat length, HTT protein length and protein context on cerebral metabolism measured using magnetic resonance spectroscopy in transgenic mouse models of Huntington's disease.
Academic Article Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis.
Academic Article Application of MRS to mouse models of neurodegenerative illness.
Academic Article Neuroprotective effects of synaptic modulation in Huntington's disease R6/2 mice.
Academic Article Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice.
Academic Article Extralarge XL(alpha)s (XXL(alpha)s), a variant of stimulatory G protein alpha-subunit (Gs(alpha)), is a distinct, membrane-anchored GNAS product that can mimic Gs(alpha).
Academic Article Anti-inflammatory treatment in AD mice protects against neuronal pathology.
Academic Article Moderate exercise delays the motor performance decline in a transgenic model of ALS.
Academic Article Longitudinal monitoring of motor neuron circuitry in FALS rats using in-vivo phMRI.
Academic Article Magnetic resonance spectroscopy of regional brain metabolite markers in FALS mice and the effects of dietary creatine supplementation.
Academic Article Detection of increased scyllo-inositol in brain with magnetic resonance spectroscopy after dietary supplementation in Alzheimer's disease mouse models.
Academic Article The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS.
Academic Article Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer''s disease.
Academic Article 7,8-Dihydroxyflavone improves motor performance and enhances lower motor neuronal survival in a mouse model of amyotrophic lateral sclerosis.
Academic Article The effects of aging, housing and ibuprofen treatment on brain neurochemistry in a triple transgene Alzheimer''s disease mouse model using magnetic resonance spectroscopy and imaging.
Academic Article R-flurbiprofen improves tau, but not Aß pathology in a triple transgenic model of Alzheimer''s disease.
Academic Article Combination therapy in a transgenic model of Alzheimer''s disease.
Academic Article Functional modulation of G-protein coupled receptors during Parkinson disease-like neurodegeneration.
Academic Article Fingolimod modulates multiple neuroinflammatory markers in a mouse model of Alzheimer''s disease.
Grant Integrated Neuroimaging and Pathology of Alzheimer Mice
Grant Anti-Inflammatory Therapy in a Mouse Model of Alzheimer’s Disease: A Magnetic Resonance Imaging, Spectroscopy and Quantitative Histopathological Study
Academic Article Combined administration of resolvin E1 and lipoxin A4 resolves inflammation in a murine model of Alzheimer''s disease.
Academic Article Anxiety, neuroinflammation, cholinergic and GABAergic abnormalities are early markers of Gulf War illness in a mouse model of the disease.
Academic Article Protective effects of 7,8-dihydroxyflavone on neuropathological and neurochemical changes in a mouse model of Alzheimer''s disease.
Academic Article Corrigendum to "Anxiety, neuroinflammation, cholinergic and GABAergic abnormalities are early markers of Gulf War illness in a mouse model of the disease" [Brain Res. 1681 (2018) 34-43].
Academic Article Vasoactive Intestinal Peptide Decreases ß-Amyloid Accumulation and Prevents Brain Atrophy in the 5xFAD Mouse Model of Alzheimer''s Disease.
Academic Article Dual dose-dependent effects of fingolimod in a mouse model of Alzheimer''s disease.
Grant Mechanistic Link Between Alzheimer's Disease and Periodontitis
Grant Mouse Breeding Colonies for Neurodegenerative Diseases
Grant Sphingosine-1-phosphate induced modulation of inflammation
Academic Article A Preliminary Study of Cu Exposure Effects upon Alzheimer''s Amyloid Pathology.
Grant Fingolimod therapy in models of Alzheimer's disease
Grant Mechanistic link between Alzheimer's disease and periodontitis
Grant Personnel Agreement for Research Services of Nurgul Aytan
Grant Sphingosine-1-phosphate induced modulation of inflammation in aging and Alzheimer's disease
Grant Mechanisms of Resolvin E1 in Periodontal Regeneration (admin supplement)
Grant Cyclohexanehexol Therapy in Transgenic Models of Alzheimer's Disease
Grant Interpersonnel Agreement for Sudarshana Sengupta
Academic Article Microglial response to experimental periodontitis in a murine model of Alzheimer''s disease.

Highlights
Search Criteria
  • Alzheimer
  • s
  • disease