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Search Results to Neil W. Kowall, MD

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Research Expertise & Professional Interests Dr. Neil W. Kowall was born in Calgary, Canada and graduated with his MD from the University of British Columbia. He moved to Boston for postgraduate training in Internal Medicine at the Beth Israel Deaconess Hospital followed by a Neurology residency at Massachusetts General Hospital. After finishing his clinical training, he completed a postdoctoral research fellowship and was appointed Assistant Professor of Neurology at Massachusetts General Hospital and Harvard Medical School. He moved to the VA and Boston University in 1992 where he is currently Professor of Neurology and Pathology, Chief of Neurology at VA Boston Healthcare System, Director of the VA New England Geriatric Research Education and Clinical Center and Director of the NIH-funded Boston University Alzheimer’s Disease Center. He has published over 199 original reports. His major research interests are human neuroanatomy and neuropathology and the use of animal models to test novel therapies for neurodegenerative diseases including Alzheimer’s disease. Dr. Kowall’s research interests include the following: human neuroanatomy, immunocytochemistry and enzyme histochemistry of the brain, neuropathological basis of neurological disorders, animal models of neurological diseases, geriatric neurology, and cognitive decline in the elderly.

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Concept Neurodegenerative Diseases
Academic Article Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington's disease mice.
Academic Article Somatostatin: alterations in the central nervous system in neurological diseases.
Academic Article Cortical somatostatin, neuropeptide Y, and NADPH diaphorase neurons: normal anatomy and alterations in Alzheimer's disease.
Academic Article Alterations of neuropeptide Y in neurological disorders
Academic Article Gilles de la Tourette's syndrome. A postmortem neuropathological and immunohistochemical study.
Academic Article The Neuropathology of Huntington’s Disease
Academic Article Mitochondrial Dysfunction as a Model for Huntington's Disease Using the Electron Transport Chain Inhibitor, 3-Nitropropionic Acid
Academic Article Substance P and substance P receptor histochemistry in human neurodegenerative diseases.
Academic Article Beta-amyloid deposition in chronic traumatic encephalopathy.
Academic Article Assessing clinicopathological correlation in chronic traumatic encephalopathy: rationale and methods for the UNITE study.
Academic Article Transcriptome analyses of chronic traumatic encephalopathy show alterations in protein phosphatase expression associated with tauopathy.
Academic Article Remodeling of heterochromatin structure slows neuropathological progression and prolongs survival in an animal model of Huntington''s disease.
Academic Article Metabolomic Analysis Identifies Alterations of Amino Acid Metabolome Signatures in the Postmortem Brain of Alzheimer''s Disease.
Academic Article Alterations of transcriptome signatures in head trauma-related neurodegenerative disorders.
Academic Article Neuropathological profile of long-duration amyotrophic lateral sclerosis in military Veterans.

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  • neuropathological
  • alterations
  • neurodegenerative diseases