Search Results to John H. Connor, PhD

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Research Expertise & Professional Interests My laboratory studies the virus-host interaction. We take a variety of approaches from genetic to systems biology to biochemistry and molecular biology. We are studying how viruses take over the cellular protein synthesis apparatus, how cells effectively fight virus infection, and how the host responds to infection with viruses that cause hemorrhagic fever.
Self-Described Keywords virus-host interaction

One or more keywords matched the following items that are connected to Connor, John

Item TypeName
Concept Zika Virus
Concept Chikungunya virus
Concept Dengue Virus
Concept Encephalitis Virus, Venezuelan Equine
Concept Lassa virus
Concept Marburg Virus Disease
Concept Monkeypox virus
Concept Myxoma virus
Concept Vaccinia virus
Concept Vesicular stomatitis Indiana virus
Concept Virus Cultivation
Concept Virus Diseases
Concept Virus Replication
Concept Virus Integration
Concept La Crosse virus
Concept Virus Physiological Phenomena
Concept Virus Assembly
Concept Virus Attachment
Concept Virus Internalization
Concept gag Gene Products, Human Immunodeficiency Virus
Concept Virus Release
Academic Article Vesicular stomatitis virus infection alters the eIF4F translation initiation complex and causes dephosphorylation of the eIF4E binding protein 4E-BP1.
Academic Article Replication and cytopathic effect of oncolytic vesicular stomatitis virus in hypoxic tumor cells in vitro and in vivo.
Academic Article Inhibition of host and viral translation during vesicular stomatitis virus infection. eIF2 is responsible for the inhibition of viral but not host translation.
Academic Article Role of residues 121 to 124 of vesicular stomatitis virus matrix protein in virus assembly and virus-host interaction.
Academic Article Preferential translation of vesicular stomatitis virus mRNAs is conferred by transcription from the viral genome.
Academic Article Antiviral activity and RNA polymerase degradation following Hsp90 inhibition in a range of negative strand viruses.
Academic Article New mRNAs are preferentially translated during vesicular stomatitis virus infection.
Academic Article Capture and transfer of HIV-1 particles by mature dendritic cells converges with the exosome-dissemination pathway.
Academic Article hnRNPs Relocalize to the cytoplasm following infection with vesicular stomatitis virus.
Academic Article Vesicular stomatitis virus matrix protein mutations that affect association with host membranes and viral nucleocapsids.
Academic Article Akt inhibitor Akt-IV blocks virus replication through an Akt-independent mechanism.
Academic Article Inhibition of heat-shock protein 90 reduces Ebola virus replication.
Academic Article Dominant inhibition of Akt/protein kinase B signaling by the matrix protein of a negative-strand RNA virus.
Academic Article Formation of antiviral cytoplasmic granules during orthopoxvirus infection.
Academic Article Label-free multiplexed virus detection using spectral reflectance imaging.
Academic Article Development of Vaccinia reporter viruses for rapid, high content analysis of viral function at all stages of gene expression.
Academic Article Identification of a pyridopyrimidinone inhibitor of orthopoxviruses from a diversity-oriented synthesis library.
Academic Article In vitro inhibition of monkeypox virus production and spread by Interferon-ß.
Academic Article A vesiculovirus showing a steepened transcription gradient and dominant trans-repression of virus transcription.
Academic Article HijAkt: The PI3K/Akt pathway in virus replication and pathogenesis.
Academic Article Translational control by negative-strand RNA viruses: methods for the study of a crucial virus/host interaction.
Academic Article Myxoma and vaccinia viruses bind differentially to human leukocytes.
Academic Article Identification of a broad-spectrum inhibitor of viral RNA synthesis: validation of a prototype virus-based approach.
Academic Article Transcriptional profiling of the circulating immune response to lassa virus in an aerosol model of exposure.
Academic Article An interferometric reflectance imaging sensor for point of care viral diagnostics.
Academic Article A single vertebrate DNA virus protein disarms invertebrate immunity to RNA virus infection.
Academic Article Discovery of a novel compound with anti-venezuelan equine encephalitis virus activity that targets the nonstructural protein 2.
Academic Article Probing the virus host interaction in high containment: an approach using pooled short hairpin RNA.
Academic Article The master regulator of the cellular stress response (HSF1) is critical for orthopoxvirus infection.
Academic Article Vaccinia reporter viruses for quantifying viral function at all stages of gene expression.
Academic Article Digital sensing and sizing of vesicular stomatitis virus pseudotypes in complex media: a model for Ebola and Marburg detection.
Academic Article Temporal Characterization of Marburg Virus Angola Infection following Aerosol Challenge in Rhesus Macaques.
Academic Article Transcriptional Profiling of the Immune Response to Marburg Virus Infection.
Academic Article Activation of stress response pathways promotes formation of antiviral granules and restricts virus replication.
Academic Article Lassa and Marburg viruses elicit distinct host transcriptional responses early after infection.
Academic Article Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus.
Academic Article In vivo Ebola virus infection leads to a strong innate response in circulating immune cells.
Academic Article New Approaches for Virus Detection through Multidisciplinary Partnerships.
Academic Article Hypusination of eIF5A as a Target for Antiviral Therapy.
Academic Article Polyamines and Hypusination Are Required for Ebolavirus Gene Expression and Replication.
Academic Article Generating Recombinant Vesicular Stomatitis Viruses for Use as Vaccine Platforms.
Academic Article Zika virus induced cellular remodelling.
Grant Control of the eIF4F Complex by Vesicular Stomatitis Virus
Academic Article Enhanced light microscopy visualization of virus particles from Zika virus to filamentous ebolaviruses.
Academic Article Variable Inhibition of Zika Virus Replication by Different Wolbachia Strains in Mosquito Cell Cultures.
Academic Article Spontaneous Mutation at Amino Acid 544 of the Ebola Virus Glycoprotein Potentiates Virus Entry and Selection in Tissue Culture.
Academic Article An RNA polymerase II-driven Ebola virus minigenome system as an advanced tool for antiviral drug screening.
Academic Article Polyamines and Their Role in Virus Infection.
Academic Article Host Transcriptional Response to Ebola Virus Infection.
Academic Article Group B Wolbachia Strain-Dependent Inhibition of Arboviruses.
Academic Article A conserved transcriptional response to intranasal Ebola virus exposure in nonhuman primates prior to onset of fever.
Academic Article Dual Insect specific virus infection limits Arbovirus replication in Aedes mosquito cells.
Academic Article Wolbachia wStri Blocks Zika Virus Growth at Two Independent Stages of Viral Replication.
Academic Article T-Cell Receptor Diversity and the Control of T-Cell Homeostasis Mark Ebola Virus Disease Survival in Humans.
Academic Article Growth-Adaptive Mutations in the Ebola Virus Makona Glycoprotein Alter Different Steps in the Virus Entry Pathway.
Academic Article Differential Mechanisms for the Involvement of Polyamines and Hypusinated eIF5A in Ebola Virus Gene Expression.
Grant Assessment of infection route and vulnerability of neural precursor classes to Zika virus
Grant role for polyamines in Ebola Virus Replication
Academic Article Previremic Identification of Ebola or Marburg Virus Infection Using Integrated Host-Transcriptome and Viral Genome Detection.

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