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Search Results to Michael F. Holick, MD, PhD

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Research Expertise & Professional Interests Dr. Holick has made numerous contributions to the field of the biochemistry, physiology, metabolism, and photobiology of vitamin D for human nutrition. Dr. Holick has established global recommendations advising sunlight exposure as an integral source of vitamin D. He has helped increase awareness in the pediatric and medical communities regarding vitamin D deficiency pandemic, and its role in causing not only metabolic bone disease, and osteoporosis in adults, but increasing risk of children and adults developing preeclampsia, common deadly cancers, schizophrenia, infectious diseases including TB and influenza, autoimmune diseases including type 1 diabetes and multiple sclerosis, type 2 diabetes, stroke and heart disease. Dr. Holick is a Diplomate of the American Board of Internal Medicine, a Fellow of the American College of Nutrition, and a member of the American Association of Physicians. He is the recipient of numerous awards and honors, including the General Clinical Research Centers Program Award for Excellence in Clinical Research from NIH, American College of Nutrition’s Communication Media Award, Best Docs in America, the Linus Pauling Functional Medicine Award from the Institute for Functional Medicine and the Linus Pauling Prize for Human Nutrition. Dr. Holick serves on a number of national committees and editorial boards and has organized and/or co-chaired several international symposia. He served as the chair for the Endocrine Society’s Practice Guidelines on Vitamin D. He has authored more than 400 peer-reviewed publications, and written more than 200 review articles, as well as numerous book chapters. He has acted as editor and/or co-editor on 13 books, and has written The UV Advantage in 2004 and The Vitamin D Solution in 2010 and helped develop the dminder.info app.
Self-Described Keywords cancer

One or more keywords matched the following items that are connected to Holick, Michael

Item TypeName
Concept Breast Neoplasms
Concept Colonic Neoplasms
Concept Combined Modality Therapy
Concept Drug Therapy, Combination
Concept Exercise Therapy
Concept Liver Neoplasms
Concept Lung Neoplasms
Concept Neoplasms
Concept Neoplasms, Experimental
Concept Neoplasms, Hormone-Dependent
Concept Neoplasms, Radiation-Induced
Concept Pancreatic Neoplasms
Concept Prostatic Neoplasms
Concept Skin Neoplasms
Concept Thyroid Neoplasms
Concept Ultraviolet Therapy
Concept Colorectal Neoplasms
Concept Genetic Therapy
Concept Estrogen Replacement Therapy
Concept Treatment Outcome
Concept Neoplasms, Basal Cell
Concept Muscle Neoplasms
Concept Hormone Replacement Therapy
Concept Epigenomics
Academic Article Increased PKC activity in cultured human keratinocytes and fibroblasts after treatment with 1 alpha, 25-dihydroxyvitamin D3.
Academic Article Therapy with parenteral pamidronate prevents thyroid hormone-induced bone turnover in humans.
Academic Article Effects of the vitamin D3 analog 1 alpha, 25-dihydroxyvitamin D3-3 beta-bromoacetate on rat osteosarcoma cells: comparison with 1 alpha, 25-dihydroxyvitamin D3.
Academic Article Topical calcitriol (1,25-dihydroxyvitamin D3) treatment of psoriasis: an immunohistological evaluation.
Academic Article 1,25-dihydroxyvitamin D3 and 1, alpha-hydroxyvitamin D3 in children: biologic and therapeutic effects in nutritional rickets and different types of vitamin D resistance.
Academic Article Active vitamin D compounds and analogues: a new therapeutic era for dermatology in the 21st century.
Academic Article Treatment of hypoparathyroidism and pseudohypoparathyroidism with metabolites of vitamin D: evidence for impaired conversion of 25-hydroxyvitamin D to 1 alpha,25-dihydroxyvitamin D.
Academic Article Efficacy and safety of topical calcitriol (1,25-dihydroxyvitamin d3) for the treatment of psoriasis.
Academic Article Safety and efficacy of oral calcitriol (1,25-dihydroxyvitamin D3) for the treatment of psoriasis.
Academic Article Human prostate cells synthesize 1,25-dihydroxyvitamin D3 from 25-hydroxyvitamin D3.
Academic Article Ultraviolet B and blood pressure.
Academic Article Immunological responses to ultraviolet light B radiation in Black individuals.
Academic Article Serum vitamin D metabolite levels and the subsequent development of prostate cancer (Hawaii, United States)
Academic Article Analysis of 1,25-dihydroxyvitamin D(3) receptors (VDR) in basal cell carcinomas.
Academic Article Sunlight "D"ilemma: risk of skin cancer or bone disease and muscle weakness.
Academic Article 25-hydroxyvitamin D-1alpha-hydroxylase in normal and malignant colon tissue.
Academic Article The in vitro evaluation of 25-hydroxyvitamin D3 and 19-nor-1alpha,25-dihydroxyvitamin D2 as therapeutic agents for prostate cancer.
Academic Article Calcium and vitamin D. Diagnostics and therapeutics.
Academic Article Rationale for use and clinical responsiveness of hexafluoro-1,25-dihydroxyvitamin D3 for the treatment of plaque psoriasis: a pilot study.
Academic Article Enhancing 1 alpha-hydroxylase activity with the 25-hydroxyvitamin D-1 alpha-hydroxylase gene in cultured human keratinocytes and mouse skin.
Academic Article 1,25-Dihydroxyvitamin D3 for the treatment of psoriasis.
Academic Article Prediagnostic serum levels of 1,25-dihydroxyvitamin D and malignant melanoma.
Academic Article A new strategy for modulating chemotherapy-induced alopecia, using PTH/PTHrP receptor agonist and antagonist.
Academic Article Treatment of vitamin D deficiency due to Crohn's disease with tanning bed ultraviolet B radiation.
Academic Article Does sunscreen block the skin's ability to make vitamin D? If so, how can I get enough of this vitamin without raising my risk of skin cancer?
Academic Article 25-Hydroxyvitamin D-1alpha-hydroxylase activity is diminished in human prostate cancer cells and is enhanced by gene transfer.
Academic Article Prostatic 25-hydroxyvitamin D-1alpha-hydroxylase and its implication in prostate cancer.
Academic Article Evolution and function of vitamin D.
Academic Article Regulation of the 25-hydroxyvitamin D-1alpha-hydroxylase gene and its splice variant.
Academic Article Vitamin D autocrine system and prostate cancer.
Academic Article Analysis of the vitamin D system in cutaneous malignancies.
Academic Article Evaluation of vitamin D analogs as therapeutic agents for prostate cancer.
Academic Article Pancreatic cancer cells express 25-hydroxyvitamin D-1 alpha-hydroxylase and their proliferation is inhibited by the prohormone 25-hydroxyvitamin D3.
Academic Article Oncogenic osteomalacia: clinical presentation, densitometric findings, and response to therapy.
Academic Article Prevalence of vitamin D deficiency in patients attending an outpatient cancer care clinic in Boston.
Academic Article Topical PTH (1-34) is a novel, safe and effective treatment for psoriasis: a randomized self-controlled trial and an open trial.
Academic Article Vitamin D and prostate cancer prevention and treatment.
Academic Article The prostate 25-hydroxyvitamin D-1 alpha-hydroxylase is not influenced by parathyroid hormone and calcium: implications for prostate cancer chemoprevention by vitamin D.
Academic Article Analysis of the vitamin D system in cutaneous squamous cell carcinomas.
Academic Article Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis.
Academic Article Topical paricalcitol (19-nor-1 alpha,25-dihydroxyvitamin D2) is a novel, safe and effective treatment for plaque psoriasis: a pilot study.
Academic Article Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease.
Academic Article Plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D and risk of breast cancer.
Academic Article Colon cancer and solar ultraviolet B radiation and prevention and treatment of colon cancer in mice with vitamin D and its Gemini analogs.
Academic Article Vitamin D and prevention of colorectal cancer.
Academic Article The vitamin D epidemic and its health consequences.
Academic Article PTH (1-34): a novel anabolic drug for the treatment of osteoporosis.
Academic Article The role of vitamin D in cancer prevention.
Academic Article Inhibition of proliferation and induction of apoptosis by 25-hydroxyvitamin D3-3beta-(2)-Bromoacetate, a nontoxic and vitamin D receptor-alkylating analog of 25-hydroxyvitamin D3 in prostate cancer cells.
Academic Article Prevalence of Vitamin D inadequacy among postmenopausal North American women receiving osteoporosis therapy.
Academic Article Vitamin D for health and in chronic kidney disease.
Academic Article Comparisons of estimated economic burdens due to insufficient solar ultraviolet irradiance and vitamin D and excess solar UV irradiance for the United States.
Academic Article Vitamin D deficiency enhances the growth of MC-26 colon cancer xenografts in Balb/c mice.
Academic Article Review of treatment modalities for postmenopausal osteoporosis.
Academic Article Vitamin D: important for prevention of osteoporosis, cardiovascular heart disease, type 1 diabetes, autoimmune diseases, and some cancers.
Academic Article Vitamin D: its role in cancer prevention and treatment.
Academic Article Calcium plus vitamin D and the risk of colorectal cancer.
Academic Article Low bone density in patients receiving methadone maintenance treatment.
Academic Article Epidemic influenza and vitamin D.
Academic Article Evaluation of C-2-substituted 19-nor-1alpha,25-dihydroxyvitamin D3 analogs as therapeutic agents for prostate cancer.
Academic Article Optimal vitamin D status for colorectal cancer prevention: a quantitative meta analysis.
Academic Article A higher dose of vitamin d reduces the risk of falls in nursing home residents: a randomized, multiple-dose study.
Academic Article High prevalence of vitamin D inadequacy and implications for health.
Academic Article Vitamin D and cancer.
Academic Article Vitamin D metabolism in human prostate cells: implications for prostate cancer chemoprevention by vitamin D.
Academic Article Analysis of 25-hydroxyvitamin D3-1alpha-hydroxylase in normal and malignant breast tissue.
Academic Article Comparison of the effects of a new conjugated oral estrogen, estradiol-3beta-glucoside, with oral micronized 17beta-estradiol in postmenopausal women.
Academic Article 1alpha,25-Dihydroxyvitamin D and fish oil synergistically inhibit G1/S-phase transition in prostate cancer cells.
Academic Article Calcitriol derivatives with two different side chains at C-20 III. An epimeric pair of the gemini family with unprecedented antiproliferative effects on tumor cells and renin mRNA expression inhibition.
Academic Article Treatment of low-risk myelodysplastic syndromes with high-dose daily oral cholecalciferol (2000-4000 IU vitamin D(3)).
Academic Article Vitamin D and prevention of breast cancer: pooled analysis.
Academic Article Selective vitamin D receptor modulators and their effects on colorectal tumor growth.
Academic Article Vitamin d and rehabilitation: improving functional outcomes.
Academic Article SOLAR ultraviolet radiation and vitamin D: a historical perspective.
Academic Article Treatment of vitamin D deficiency with UV light in patients with malabsorption syndromes: a case series.
Academic Article Sickle cell bone disease: response to vitamin D and calcium.
Academic Article Optimal vitamin D status for the prevention and treatment of osteoporosis.
Academic Article Sunlight, UV-radiation, vitamin D and skin cancer: how much sunlight do we need?
Academic Article Vitamin D deficiency: a worldwide problem with health consequences.
Academic Article Michael Holick, PhD, MD: vitamin D pioneer. Interview by Frank Lampe and Suzanne Snyder.
Academic Article Does vitamin D3 dosing schedule influence treatment efficacy in nursing home residents with vitamin D deficiency?
Academic Article Inhibition of RelB by 1,25-dihydroxyvitamin D3 promotes sensitivity of breast cancer cells to radiation.
Academic Article Vitamin D and sunlight: strategies for cancer prevention and other health benefits.
Academic Article Refractory hypocalcemia following near-total thyroidectomy in a patient with a prior Roux-en-Y gastric bypass.
Academic Article Prostate cancer survival: is there a dietary connection?
Academic Article Chemoprevention of colorectal neoplasia.
Academic Article Alendronate/vitamin D3 70 mg/2800 IU with and without additional 2800 IU vitamin D3 for osteoporosis: results from the 24-week extension of a 15-week randomized, controlled trial.
Academic Article Standard multivitamin supplementation does not improve vitamin D insufficiency after burns.
Academic Article Multiple myeloma and cancer: is there a D-lightful connection?
Academic Article Evaluation of 19-nor-2alpha-(3-hydroxypropyl)-1alpha,25-dihydroxyvitamin D3 as a therapeutic agent for androgen-dependent prostate cancer.
Academic Article Fish oil enhances the antiproliferative effect of 1alpha,25-dihydroxyvitamin D3 on liver cancer cells.
Academic Article Vitamin D2 treatment for vitamin D deficiency and insufficiency for up to 6 years.
Academic Article Will 1,25-dihydroxyvitamin D3, MC 903, and their analogues herald a new pharmacologic era for the treatment of psoriasis?
Academic Article Shining light on the vitamin D: Cancer connection IARC report.
Academic Article Open letter to IARC Director Christopher P. Wild-Re: IARC Working Group Report 5: Vitamin D and Cancer.
Academic Article Vitamin D: extraskeletal health.
Academic Article 20-Hydroxyvitamin D2 is a noncalcemic analog of vitamin D with potent antiproliferative and prodifferentiation activities in normal and malignant cells.
Academic Article Diagnosis and treatment of osteopenia.
Academic Article The D-batable Institute of Medicine report: a D-lightful perspective.
Academic Article Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline.
Academic Article Low vitamin d status of patients in methadone maintenance treatment.
Academic Article Solar UV doses of young Americans and vitamin D3 production.
Academic Article Chronic sunscreen use decreases circulating concentrations of 25-hydroxyvitamin D. A preliminary study.
Academic Article Treatment with 50,000 IU vitamin D2 every other week and effect on serum 25-hydroxyvitamin D2, 25-hydroxyvitamin D3, and total 25-hydroxyvitamin D in a clinical setting.
Academic Article Effect of dietary vitamin D and calcium on the growth of androgen-insensitive human prostate tumor in a murine model.
Academic Article Hypercalcemia associated with mineral oil-induced sclerosing paraffinomas.
Academic Article Optimize dietary intake of vitamin D: an epigenetic perspective.
Academic Article Vitamin D, sunlight and cancer connection.
Academic Article Treatment of psoriatic arthritis with oral 1,25-dihydroxyvitamin D3: a pilot study.
Academic Article Vitamin D - effects on skeletal and extraskeletal health and the need for supplementation.
Academic Article Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality-a review of recent evidence.
Academic Article Practical guidelines for the supplementation of vitamin D and the treatment of deficits in Central Europe - recommended vitamin D intakes in the general population and groups at risk of vitamin D deficiency.
Academic Article Vitamin D favorably alters the cancer promoting prostaglandin cascade.
Academic Article A novel approach for the evaluation and treatment of psoriasis. Oral or topical use of 1,25-dihydroxyvitamin D3 can be a safe and effective therapy for psoriasis.
Academic Article 1,25-Dihydroxyvitamin D3 and the skin: a unique application for the treatment of psoriasis.
Academic Article Skin as the site of vitamin D synthesis and target tissue for 1,25-dihydroxyvitamin D3. Use of calcitriol (1,25-dihydroxyvitamin D3) for treatment of psoriasis.
Academic Article X-linked hypophosphataemic rickets: Inadequate therapeutic response to 1,25-dihydroxycholecalciferol.
Academic Article Increased skin pigment reduces the capacity of skin to synthesise vitamin D3.
Academic Article The photoproduction of 1 alpha,25-dihydroxyvitamin D3 in skin: an approach to the therapy of vitamin-D-resistant syndromes.
Academic Article Vitamin-D synthesis and metabolism after ultraviolet irradiation of normal and vitamin-D-deficient subjects.
Academic Article Sunlight, ultraviolet radiation, vitamin D and skin cancer: how much sunlight do we need?
Academic Article Molecular Mechanism(s) Involved in 25-Hydroxyvitamin D''s Antiproliferative Effects in CYP27B1-transfected LNCaP Cells.
Academic Article Shedding new light on the role of the sunshine vitamin D for skin health: the lncRNA-skin cancer connection.
Academic Article Targeting the vitamin D endocrine system (VDES) for the management of inflammatory and malignant skin diseases: An historical view and outlook.
Academic Article Biologic Effects of Light: An Enlighting Prospective.
Academic Article Biological Effects of Sunlight, Ultraviolet Radiation, Visible Light, Infrared Radiation and Vitamin D for Health.
Academic Article Micronutrients in Oncological Intervention.
Academic Article Vitamin D3 Treatment Influences PGE2 and TGFß in Normal and Increased Breast Cancer Risk Women.
Academic Article Sunlight and Vitamin D: Necessary for Public Health.
Academic Article Predicted 25-hydroxyvitamin D in relation to incidence of breast cancer in a large cohort of African American women.
Academic Article The vitamin D deficiency pandemic: Approaches for diagnosis, treatment and prevention.
Grant Comparison of the Therapeutic Efficacy of Topically Administered 19-nor-1,25(OH)D3 & Dovonex in Treating Psoriasis
Grant Therapy for Chemotherapy Alopecia with PTHrP Analogs
Academic Article Cancer, sunlight and vitamin D.
Academic Article A Critical Appraisal of the Recent Reports on Sunbeds from the European Commission''s Scientific Committee on Health, Environmental and Emerging Risks and from the World Health Organization.
Academic Article Calcium and vitamin D supplementation and/or periodontal therapy in the treatment of periodontitis among Brazilian pregnant women: protocol of a feasibility randomised controlled trial (the IMPROVE trial).
Academic Article Vitamin D deficiency and its relationship to cancer stage in patients who underwent thyroidectomy for papillary thyroid carcinoma.
Academic Article The ongoing D-lemma of vitamin D supplementation for nonskeletal health and bone health.
Academic Article Vitamin D Status as a Predictor of Postoperative Hypocalcemia after Thyroidectomy.
Academic Article Sunlight, UV Radiation, Vitamin D, and Skin Cancer: How Much Sunlight Do We Need?
Academic Article Vitamin D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng/mL reduced risk for adverse clinical outcomes in patients with COVID-19 infection.
Academic Article Correction to: Calcium and vitamin D supplementation and/or periodontal therapy in the treatment of periodontitis among Brazilian pregnant women: protocol of a feasibility randomised controlled trial (the IMPROVE trial).

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