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Research Expertise & Professional Interests Jerrold Ellner, MD is Adjunct Professor of Medicine in Infectious Diseases at Boston University School of Medicine and at Rutgers New Jersey Medical School. He has studied the immunopathogenesis of TB and TB in HIV through research collaborations in Uganda and Brazil. He has conducted clinical trials of the prevention of treatment of TB as well as the first HIV/AIDS Vaccine Trial in Africa. His research group was the first to show that TB accelerated the course of HIV infection by activating viral replication in latently infected cells. He was one of the principal architects of the Uganda-Case Western Reserve University Research Collaboration, a founding member of the Academic Alliance for AIDS Prevention and Care in Africa which developed the Infectious Diseases Institute at Makerere University, and the founding director of the TB Research Unit at Case Western Reserve University. He is PI of an International Collaboration for Infectious Diseases Research (ICIDR) program in Brazil and the TB – Clinical Diagnostics Research Consortium (CDRC). He has authored more than 250 publications on TB and has trained a number of current academic leaders in infectious diseases.
Self-Described Keywords infectious diseases
Self-Described Keywords diagnostics

One or more keywords matched the following items that are connected to Ellner, Jerrold

Item TypeName
Concept Acute Disease
Concept Autoimmune Diseases
Concept Brain Diseases
Concept Central Nervous System Diseases
Concept Chronic Disease
Concept Communicable Disease Control
Concept Disease Models, Animal
Concept Disease Outbreaks
Concept Disease Susceptibility
Concept Liver Diseases
Concept Liver Diseases, Parasitic
Concept Lung
Concept Lyme Disease
Concept Nose Diseases
Concept Occupational Diseases
Concept Skin Diseases
Concept Splenic Diseases
Concept Virus Diseases
Concept Biomarkers
Concept Infectious Disease Transmission, Patient-to-Professional
Concept Disease Progression
Concept Disease Transmission, Infectious
Concept Infectious Disease Medicine
Academic Article Monocyte-mediated killing of schistosomula of Schistosoma mansoni: alterations in human Schistosomiasis mansoni and tuberculosis.
Academic Article Two cases of rhinocerebral zygomycosis (mucormycosis) with common epidemiologic and environmental features.
Academic Article Cytokines and tuberculosis.
Academic Article Generalized immune activation in pulmonary tuberculosis: co-activation with HIV infection.
Academic Article Site of disease and opportunistic infection predict survival in HIV-associated tuberculosis.
Academic Article Immunosuppression in tuberculosis.
Academic Article Immune activation, allergic drug toxicity and mortality in HIV-positive tuberculosis.
Academic Article Pulmonary tuberculosis in a BCG vaccinated area: relationship of disease severity with immunological and hematological parameters and drug resistance patterns.
Academic Article Impact of human immunodeficiency virus type-1 infection on the initial bacteriologic and radiographic manifestations of pulmonary tuberculosis in Uganda. Makerere University-Case Western Reserve University Research Collaboration.
Academic Article Examining a paradox in the pathogenesis of human pulmonary tuberculosis: immune activation and suppression/anergy.
Academic Article Risk factors for adverse drug reactions during thiacetazone treatment of pulmonary tuberculosis in human immunodeficiency virus infected adults.
Academic Article Risk factors for relapse in human immunodeficiency virus type 1 infected adults with pulmonary tuberculosis.
Academic Article Immunological screening of a genomic M. bovis BCG library expressed in M. smegmatis and identification of the M. bovis BCG analog of ClpB.
Academic Article Scientific advances necessary for tuberculosis control.
Academic Article Pulmonary tuberculosis.
Academic Article Measurement of sputum Mycobacterium tuberculosis messenger RNA as a surrogate for response to chemotherapy.
Academic Article The effect of bacille Calmette-Guérin vaccination at birth on tuberculin skin test reactivity in Ugandan children.
Academic Article PPD-specific IgG1 antibody subclass upregulate tumour necrosis factor expression in PPD-stimulated monocytes: possible link with disease pathogenesis in tuberculosis.
Academic Article Efficacy of an unsupervised 8-month rifampicin-containing regimen for the treatment of pulmonary tuberculosis in HIV-infected adults. Uganda-Case Western Reserve University Research Collaboration.
Academic Article Quantitative bacillary response to treatment in Mycobacterium tuberculosis infected and M. africanum infected adults with pulmonary tuberculosis.
Academic Article Quantitative sputum bacillary load during rifampin-containing short course chemotherapy in human immunodeficiency virus-infected and non-infected adults with pulmonary tuberculosis.
Academic Article Correlates of protective immunity to Mycobacterium tuberculosis in humans.
Academic Article Impact of pulmonary tuberculosis on survival of HIV-infected adults: a prospective epidemiologic study in Uganda.
Academic Article Chronic meningitis.
Academic Article Inhibition of isoniazid-induced expression of Mycobacterium tuberculosis antigen 85 in sputum: potential surrogate marker in tuberculosis chemotherapy trials.
Academic Article The human immune response to Mycobacterium Tuberculosis infection and disease.
Academic Article Activation of beta-chemokines and CCR5 in persons infected with human immunodeficiency virus type 1 and tuberculosis.
Academic Article Whither Mycobacterium vaccae--encore.
Academic Article Sputum cytokine levels in patients with pulmonary tuberculosis as early markers of mycobacterial clearance.
Academic Article Bactericidal activity in whole blood as a potential surrogate marker of immunity after vaccination against tuberculosis.
Academic Article Investigation of the relationships between immune-mediated inhibition of mycobacterial growth and other potential surrogate markers of protective Mycobacterium tuberculosis immunity.
Academic Article Regulation of the human cellular immune response to Mycobacterium tuberculosis. The mechanism of selective depression of the response to PPD.
Academic Article Tuberculosis infection among HCWs.
Academic Article Mycobacterium tuberculosis growth control by lung macrophages and CD8 cells from patient contacts.
Academic Article Comparison of intermittent ethambutol with rifampicin-based regimens in HIV-infected adults with PTB, Kampala.
Academic Article Effect of tuberculosis preventive therapy on HIV disease progression and survival in HIV-infected adults.
Academic Article Low-cost rapid detection of rifampicin resistant tuberculosis using bacteriophage in Kampala, Uganda.
Academic Article Concurrent responses of peripheral blood and splenic mononuclear cells to antigenic and mitogenic stimulation in human hepatosplenic schistosomiasis.
Academic Article Dissociation of immunoregulatory function of blood monocytes from maturational state and expression of interleukin-1 in humans chronically infected with Schistosoma mansoni.
Academic Article Mycobacterium avium infection and AIDS: a therapeutic dilemma in rapid evolution.
Academic Article Drug-resistant TB and HIV in resource-limited settings: what TB/HIV programmes can learn from each other.
Academic Article Compartmentalized bronchoalveolar IFN-gamma and IL-12 response in human pulmonary tuberculosis.
Academic Article Comparison of rapid tests for detection of rifampicin-resistant Mycobacterium tuberculosis in Kampala, Uganda.
Academic Article Differential expression of Toll-like receptors on human alveolar macrophages and autologous peripheral monocytes.
Academic Article Immunoregulation in TB: observations and implications.
Academic Article Management of acute and chronic respiratory tract infections.
Academic Article Bacterial colonization of the tracheobronchial tree.
Academic Article Ten challenges for TB biomarkers.
Academic Article Clinical research and development of tuberculosis diagnostics: moving from silos to synergy.
Academic Article Defective accessory function of monocytes in human immunodeficiency virus-related disease syndromes.
Academic Article Chronic Meningitis
Academic Article HIV disease progression and effects of tuberculosis preventive therapy in HIV-infected adults
Academic Article Tuberculosis and Atypical Mycobacterial Infections
Academic Article Urinary interleukins in patients receiving intravesical Bacillus Calmette-Guerin therapy for superficial bladder cancer.
Academic Article Lymphocytes of persons with the acquired immunodeficiency syndrome and related conditions express reactivity with the monoclonal antibody 4D12 reflective of in vivo lymphocyte activation.
Academic Article Buffer's belly.
Academic Article Chronic meningitis.
Academic Article Stress as a precipitating factor in subjects with recurrent herpes labialis.
Academic Article Suppressor cells of man.
Academic Article Modulation of macrophage activation and resistance by suppressor T lymphocytes in chronic murine Schistosoma mansoni infection.
Academic Article Suppression splenic T lymphocytes in human hepatosplenic Schistosomiasis mansoni.
Academic Article Haemophilus influenzae meningitis: the spectrum of disease in adults.
Academic Article Dichotomies in the reactivity to worm antigen in human schistosomiasis mansoni.
Academic Article Accelerated course of human immunodeficiency virus infection after tuberculosis.
Academic Article Absence of Mycobacterium avium complex disease in patients with AIDS in Uganda.
Academic Article Enhanced production of TGF-beta by blood monocytes from patients with active tuberculosis and presence of TGF-beta in tuberculous granulomatous lung lesions.
Academic Article Modulation of the effector function of human monocytes for Mycobacterium avium by human immunodeficiency virus-1 envelope glycoprotein gp120.
Academic Article Quest for correlates of protection against tuberculosis.
Academic Article Cost-effectiveness of novel algorithms for rapid diagnosis of tuberculosis in HIV-infected individuals in Uganda.
Academic Article Diagnostic accuracy of a rapid urine lipoarabinomannan test for tuberculosis in HIV-infected adults.
Academic Article Latent tuberculosis infection--Revisiting and revising concepts.
Academic Article RePORT International: Advancing Tuberculosis Biomarker Research Through Global Collaboration.
Academic Article Serologic Responses in Childhood Pulmonary Tuberculosis.
Academic Article Evaluation of a Rapid Molecular Drug-Susceptibility Test for Tuberculosis.
Academic Article Scientific advances necessary for tuberculosis control [The George Comstock Lecture].
Academic Article Intensity of exposure to pulmonary tuberculosis determines risk of tuberculosis infection and disease.
Academic Article "Tuberculosis in advanced HIV infection is associated with increased expression of IFN? and its downstream targets".
Award or Honor Receipt Squibb Award
Award or Honor Receipt Top Doctor, Infectious Disease
Award or Honor Receipt Top Doctor, Infectious Disease
Award or Honor Receipt Top Doctor, Infectious Disease
Academic Article Transmission phenotype of Mycobacterium tuberculosis strains is mechanistically linked to induction of distinct pulmonary pathology.
Academic Article Effect of malnutrition on radiographic findings and mycobacterial burden in pulmonary tuberculosis.
Grant TBRU - Biomarkers and Mechanisms of Paucibacillary and Latent Tuberculosis
Grant A Triage Strategy for TB Based on Inflammatory Biomarkers and Mycobacterium tuberculosis-specific…
Grant Tuberculosis Clinical Diagnostics Research Consortium (CDRC)-Administrative Core
Grant Training of Ugandans in Basic Research on TB and Emerging Infectious Diseases
Grant Tuberculosis Clinical Diagnostics Research Consortium (CDRC) - Salary, FB payments
Grant RePORT SA: The Clinical Research Unit (CRU) for Advancement of Tuberculosis Biomarkers
Grant Training of Ugandans in Basic and Translational Research on TB and Emerging Infectious Diseases
Grant RePORT India: Biomarkers for Risk of TB and for TB Treatment Failure and Relapse
Grant US Brazilian Collaboration on Immunity and Biomarkers in Tuberculosis

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