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One or more keywords matched the following properties of A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling.

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has major subject area list Membrane Glycoproteins; Myeloid Differentiation Factor 88; Receptors, Interleukin-1; Signal Transduction; Toll-Like Receptor 2; Toll-Like Receptor 4
information resource reference Nagpal K, Plantinga TS, Wong J, Monks BG, Gay NJ, Netea MG, Fitzgerald KA, Golenbock DT. A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling. J Biol Chem. 2009 Sep 18; 284(38):25742-8. PMID: 19509286.
label A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling.

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  • TLR
  • signaling