Connection

Search Results to Nikhil C. Munshi, MD

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One or more keywords matched the following items that are connected to Munshi, Nikhil C.

Item TypeName
Concept Alleles
Concept Allosteric Regulation
Concept Amino Acid Sequence
Concept Base Sequence
Concept Gene Expression Regulation
Concept Gene Frequency
Concept Genes, Dominant
Concept Genes, MHC Class II
Concept Genes, Viral
Concept Lac Operon
Concept Molecular Sequence Data
Concept Oncogenes
Concept Genes, ras
Concept Sequence Homology, Nucleic Acid
Concept Gene Rearrangement
Concept Gene Rearrangement, B-Lymphocyte, Heavy Chain
Concept Down-Regulation
Concept Gene Products, tat
Concept Gene Library
Concept Up-Regulation
Concept Gene Expression
Concept Genome, Human
Concept Gene Expression Regulation, Viral
Concept Gene Expression Regulation, Enzymologic
Concept Gene Expression Regulation, Neoplastic
Concept Genes, Tumor Suppressor
Concept Genes, p53
Concept Gene Deletion
Concept Genes, APC
Concept Genes, Reporter
Concept Gene Transfer Techniques
Concept Gene Targeting
Concept Gene Dosage
Concept Genes, bcl-2
Concept Polymorphism, Single Nucleotide
Concept Gene Silencing
Concept Gene Expression Profiling
Concept Gene Fusion
Concept Genes, Neoplasm
Concept Gene Regulatory Networks
Concept tat Gene Products, Human Immunodeficiency Virus
Concept Gene Knockdown Techniques
Concept Gene Knockout Techniques
Concept Genetic Loci
Concept Transcriptome
Concept Exome
Concept Gene Ontology
Academic Article MYD88-independent growth and survival effects of Sp1 transactivation in Waldenstrom macroglobulinemia.
Academic Article The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells.
Academic Article miR-23b/SP1/c-myc forms a feed-forward loop supporting multiple myeloma cell growth.
Academic Article Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma.
Academic Article Dual PAK4-NAMPT Inhibition Impacts Growth and Survival, and Increases Sensitivity to DNA-Damaging Agents in Waldenström Macroglobulinemia.
Academic Article Immunomodulatory drug costimulates T cells via the B7-CD28 pathway.
Academic Article Telomerase inhibitor GRN163L inhibits myeloma cell growth in vitro and in vivo.
Academic Article Aplidin, a marine organism-derived compound with potent antimyeloma activity in vitro and in vivo.
Academic Article Therapeutic vulnerability of multiple myeloma to MIR17PTi, a first-in-class inhibitor of pri-miR-17-92.
Academic Article Targeting PKC: a novel role for beta-catenin in ER stress and apoptotic signaling.
Academic Article Consensus recommendations for risk stratification in multiple myeloma: report of the International Myeloma Workshop Consensus Panel 2.
Academic Article Specific killing of multiple myeloma cells by (-)-epigallocatechin-3-gallate extracted from green tea: biologic activity and therapeutic implications.
Academic Article Widespread intronic polyadenylation diversifies immune cell transcriptomes.
Academic Article Didox, a ribonucleotide reductase inhibitor, induces apoptosis and inhibits DNA repair in multiple myeloma cells.
Academic Article Preclinical activity of P276-00, a novel small-molecule cyclin-dependent kinase inhibitor in the therapy of multiple myeloma.
Academic Article The bortezomib/proteasome inhibitor PS-341 and triterpenoid CDDO-Im induce synergistic anti-multiple myeloma (MM) activity and overcome bortezomib resistance.
Academic Article Gene expression analysis of B-lymphoma cells resistant and sensitive to bortezomib.
Academic Article Genomic heterogeneity in multiple myeloma.
Academic Article The biological sequelae of stromal cell-derived factor-1alpha in multiple myeloma.
Academic Article Antisense p53 transduction leads to overexpression of bcl-2 and dexamethasone resistance in multiple myeloma.
Academic Article Identification of genes regulated by 2-methoxyestradiol (2ME2) in multiple myeloma cells using oligonucleotide arrays.
Academic Article Non-overlapping Control of Transcriptome by Promoter- and Super-Enhancer-Associated Dependencies in Multiple Myeloma.
Academic Article Selective targeting of IRF4 by synthetic microRNA-125b-5p mimics induces anti-multiple myeloma activity in vitro and in vivo.
Academic Article Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications.
Academic Article Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts.
Academic Article Human immunodeficiency virus tat modulates the Flk-1/KDR receptor, mitogen-activated protein kinases, and components of focal adhesion in Kaposi''s sarcoma cells.
Academic Article Targeting homologous recombination and telomerase in Barrett''s adenocarcinoma: impact on telomere maintenance, genomic instability and tumor growth.
Academic Article Histone deacetylase 3 as a novel therapeutic target in multiple myeloma.
Academic Article NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma.
Academic Article Identification of human leucocyte antigen (HLA)-A*0201-restricted cytotoxic T lymphocyte epitopes derived from HLA-DOß as a novel target for multiple myeloma.
Academic Article SAR650984 directly induces multiple myeloma cell death via lysosomal-associated and apoptotic pathways, which is further enhanced by pomalidomide.
Academic Article Acetylation of HMG I(Y) by CBP turns off IFN beta expression by disrupting the enhanceosome.
Academic Article Targeting CD38 Suppresses Induction and Function of T Regulatory Cells to Mitigate Immunosuppression in Multiple Myeloma.
Academic Article Gene signature combinations improve prognostic stratification of multiple myeloma patients.
Academic Article Neutralizing B-cell activating factor antibody improves survival and inhibits osteoclastogenesis in a severe combined immunodeficient human multiple myeloma model.
Academic Article Inhibition of Akt induces significant downregulation of survivin and cytotoxicity in human multiple myeloma cells.
Academic Article Identification of genes modulated in multiple myeloma using genetically identical twin samples.
Academic Article Targeting the miR-221-222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma.
Academic Article Functional interaction of plasmacytoid dendritic cells with multiple myeloma cells: a therapeutic target.
Academic Article The KDM3A-KLF2-IRF4 axis maintains myeloma cell survival.
Academic Article Proteasome inhibitor PS-341 abrogates IL-6 triggered signaling cascades via caspase-dependent downregulation of gp130 in multiple myeloma.
Academic Article A 13 mer LNA-i-miR-221 Inhibitor Restores Drug Sensitivity in Melphalan-Refractory Multiple Myeloma Cells.
Academic Article Clinical, radiographic, and biochemical characterization of multiple myeloma patients with osteonecrosis of the jaw.
Academic Article Ribonucleotide Reductase Catalytic Subunit M1 (RRM1) as a Novel Therapeutic Target in Multiple Myeloma.
Academic Article A global expression-based analysis of the consequences of the t(4;14) translocation in myeloma.
Academic Article Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma.
Academic Article A proto-oncogene BCL6 is up-regulated in the bone marrow microenvironment in multiple myeloma cells.
Academic Article Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition.
Academic Article Biological pathways and in vivo antitumor activity induced by Atiprimod in myeloma.
Academic Article Outcomes in patients with relapsed or refractory multiple myeloma in a phase I study of everolimus in combination with lenalidomide.
Academic Article Proteasomal degradation of topoisomerase I is preceded by c-Jun NH2-terminal kinase activation, Fas up-regulation, and poly(ADP-ribose) polymerase cleavage in SN38-mediated cytotoxicity against multiple myeloma.
Academic Article APRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment.
Academic Article Minor clone provides a reservoir for relapse in multiple myeloma.
Academic Article Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease.
Academic Article CCR6, the sole receptor for the chemokine CCL20, promotes spontaneous intestinal tumorigenesis.
Academic Article miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/ß-catenin/BCL9 pathway.
Academic Article Gene expression profile alone is inadequate in predicting complete response in multiple myeloma.
Academic Article In vivo anti-myeloma activity and modulation of gene expression profile induced by valproic acid, a histone deacetylase inhibitor.
Academic Article miR-29b sensitizes multiple myeloma cells to bortezomib-induced apoptosis through the activation of a feedback loop with the transcription factor Sp1.
Academic Article Expression of AAV Rep proteins in SV40-transformed and untransformed cells: reciprocal interaction with host DNA synthesis.
Academic Article Graft-versus-tumor response in patients with multiple myeloma is associated with antibody response to BCMA, a plasma-cell membrane receptor.
Academic Article Dual level inhibition of E2F-1 activity by adeno-associated virus Rep78.
Academic Article Interaction of adeno-associated virus Rep78 with SV40 T antigen: implications in Rep protein expression leading to the inhibition of SV40-mediated cell proliferation.
Academic Article Identification of genes regulated by dexamethasone in multiple myeloma cells using oligonucleotide arrays.
Academic Article Heat shock protein 90 is critical for regulation of phenotype and functional activity of human T lymphocytes and NK cells.
Academic Article Therapeutic Targeting of miR-29b/HDAC4 Epigenetic Loop in Multiple Myeloma.
Academic Article Telomerase inhibition by siRNA causes senescence and apoptosis in Barrett''s adenocarcinoma cells: mechanism and therapeutic potential.
Academic Article Differential and limited expression of mutant alleles in multiple myeloma.
Academic Article Seliciclib (CYC202 or R-roscovitine), a small-molecule cyclin-dependent kinase inhibitor, mediates activity via down-regulation of Mcl-1 in multiple myeloma.
Academic Article Coordination of a transcriptional switch by HMGI(Y) acetylation.
Academic Article canEvolve: a web portal for integrative oncogenomics.
Academic Article Dysfunctional homologous recombination mediates genomic instability and progression in myeloma.
Academic Article Molecular and cellular effects of multi-targeted cyclin-dependent kinase inhibition in myeloma: biological and clinical implications.
Academic Article Pyk2 promotes tumor progression in multiple myeloma.
Academic Article p53-related protein kinase confers poor prognosis and represents a novel therapeutic target in multiple myeloma.
Academic Article Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myeloma.
Academic Article Targeting miR-21 inhibits in vitro and in vivo multiple myeloma cell growth.
Academic Article Molecular sequelae of proteasome inhibition in human multiple myeloma cells.
Academic Article JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells.
Academic Article Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341.
Academic Article Bortezomib induces canonical nuclear factor-kappaB activation in multiple myeloma cells.
Academic Article A DNA target-enrichment approach to detect mutations, copy number changes and immunoglobulin translocations in multiple myeloma.
Academic Article Insights into the multistep transformation of MGUS to myeloma using microarray expression analysis.
Academic Article Cytokines modulate telomerase activity in a human multiple myeloma cell line.
Academic Article Targeting PI3K and RAD51 in Barrett''s adenocarcinoma: impact on DNA damage checkpoints, expression profile and tumor growth.
Academic Article Chromothripsis identifies a rare and aggressive entity among newly diagnosed multiple myeloma patients.
Academic Article Individualized therapy in multiple myeloma: are we there?
Academic Article Immunotherapy in Multiple Myeloma: Accelerating on the Path to the Patient.
Academic Article Combination of a Selective HSP90a/ß Inhibitor and a RAS-RAF-MEK-ERK Signaling Pathway Inhibitor Triggers Synergistic Cytotoxicity in Multiple Myeloma Cells.
Academic Article Prognostic significance of copy-number alterations in multiple myeloma.
Academic Article Genomic patterns of progression in smoldering multiple myeloma.
Academic Article APRIL signaling via TACI mediates immunosuppression by T regulatory cells in multiple myeloma: therapeutic implications.
Academic Article Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups.
Academic Article Targeting MEK1/2 blocks osteoclast differentiation, function and cytokine secretion in multiple myeloma.
Academic Article Blockade of Deubiquitylating Enzyme USP1 Inhibits DNA Repair and Triggers Apoptosis in Multiple Myeloma Cells.
Academic Article Growth arrest, apoptosis, and telomere shortening of Barrett''s-associated adenocarcinoma cells by a telomerase inhibitor.
Academic Article Regulation of Sclerostin Expression in Multiple Myeloma by Dkk-1: A Potential Therapeutic Strategy for Myeloma Bone Disease.
Academic Article Role of apurinic/apyrimidinic nucleases in the regulation of homologous recombination in myeloma: mechanisms and translational significance.
Academic Article Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications.
Academic Article Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma.
Academic Article Complete response to donor lymphocyte infusion in multiple myeloma is associated with antibody responses to highly expressed antigens.
Academic Article The sumoylation pathway is dysregulated in multiple myeloma and is associated with adverse patient outcome.
Academic Article The shaping and functional consequences of the dosage effect landscape in multiple myeloma.
Academic Article Telomerase inhibition and cell growth arrest after telomestatin treatment in multiple myeloma.
Academic Article Significant biological role of sp1 transactivation in multiple myeloma.
Academic Article Elevated IL-17 produced by TH17 cells promotes myeloma cell growth and inhibits immune function in multiple myeloma.
Academic Article CSNK1a1 mediates malignant plasma cell survival.
Academic Article Bone marrow stromal cells as a vehicle for gene transfer.
Academic Article Logic programming reveals alteration of key transcription factors in multiple myeloma.
Academic Article Molecular characterization of PS-341 (bortezomib) resistance: implications for overcoming resistance using lysophosphatidic acid acyltransferase (LPAAT)-beta inhibitors.
Academic Article Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma.
Academic Article NF-kappa B as a therapeutic target in multiple myeloma.
Academic Article Expressed fusion gene landscape and its impact in multiple myeloma.
Academic Article A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma.
Academic Article PI3K/p110{delta} is a novel therapeutic target in multiple myeloma.
Academic Article p38 MAPK inhibition enhances PS-341 (bortezomib)-induced cytotoxicity against multiple myeloma cells.
Academic Article Phenotypic and functional effects of heat shock protein 90 inhibition on dendritic cell.
Academic Article Classify hyperdiploidy status of multiple myeloma patients using gene expression profiles.
Academic Article CS1 promotes multiple myeloma cell adhesion, clonogenic growth, and tumorigenicity via c-maf-mediated interactions with bone marrow stromal cells.
Academic Article Histone deacetylase (HDAC) inhibitor ACY241 enhances anti-tumor activities of antigen-specific central memory cytotoxic T lymphocytes against multiple myeloma and solid tumors.
Academic Article Drugging the lncRNA MALAT1 via LNA gapmeR ASO inhibits gene expression of proteasome subunits and triggers anti-multiple myeloma activity.
Academic Article Combination therapy with interleukin-6 receptor superantagonist Sant7 and dexamethasone induces antitumor effects in a novel SCID-hu In vivo model of human multiple myeloma.
Academic Article Continuous absence of metaphase-defined cytogenetic abnormalities, especially of chromosome 13 and hypodiploidy, ensures long-term survival in multiple myeloma treated with Total Therapy I: interpretation in the context of global gene expression.
Academic Article An ikaros-containing chromatin-remodeling complex in adult-type erythroid cells.
Academic Article The architectural transcription factor high mobility group I(Y) participates in photoreceptor-specific gene expression.
Academic Article MicroRNAs 15a/16-1 function as tumor suppressor genes in multiple myeloma.
Academic Article MiR-29b antagonizes the pro-inflammatory tumor-promoting activity of multiple myeloma-educated dendritic cells.
Academic Article Synthetic miR-34a mimics as a novel therapeutic agent for multiple myeloma: in vitro and in vivo evidence.
Academic Article Impact of Genes Highly Correlated with MMSET Myeloma on the Survival of Non-MMSET Myeloma Patients.
Academic Article Intracellular NAD? depletion enhances bortezomib-induced anti-myeloma activity.
Academic Article Thymidine kinase (TK) gene-transduced human lymphocytes can be highly purified, remain fully functional, and are killed efficiently with ganciclovir.
Academic Article Targeted disruption of the BCL9/ß-catenin complex inhibits oncogenic Wnt signaling.
Academic Article Antigen-mediated regulation in monoclonal gammopathies and myeloma.
Academic Article Gene Expression Profiles in Myeloma: Ready for the Real World?
Academic Article The dChip survival analysis module for microarray data.
Academic Article A multiple myeloma classification system that associates normal B-cell subset phenotypes with prognosis.
Academic Article Human MYD88L265P is insufficient by itself to drive neoplastic transformation in mature mouse B cells.
Academic Article Timing the initiation of multiple myeloma.

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  • Regulation