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Search Results to Chad Mire, PhD

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Research Expertise & Professional Interests My research focuses on understanding host-pathogen interactions of lethal negative strand RNA viruses. Using reverse genetics we characterize viruses in vitro and in vivo elucidating what is important for virus replication thereby potentially revealing pathways for small molecule inhibitors or therapeutics which can be targeted for protective benefit.

One or more keywords matched the following items that are connected to Mire, Chad

Item TypeName
Concept Zika Virus
Concept Encephalitis Virus, Venezuelan Equine
Concept Lassa virus
Concept Marburg Virus Disease
Concept Vaccinia virus
Concept Vesicular stomatitis Indiana virus
Concept Virus Cultivation
Concept Virus Replication
Concept Virus Inactivation
Concept Hendra Virus
Concept Nipah Virus
Concept Virus Internalization
Academic Article Aerosolized Ebola vaccine protects primates and elicits lung-resident T cell responses.
Academic Article Polyamines and Hypusination Are Required for Ebolavirus Gene Expression and Replication.
Academic Article Enhanced light microscopy visualization of virus particles from Zika virus to filamentous ebolaviruses.
Academic Article Recombinant vesicular stomatitis virus vaccine vectors expressing filovirus glycoproteins lack neurovirulence in nonhuman primates.
Academic Article Single injection recombinant vesicular stomatitis virus vaccines protect ferrets against lethal Nipah virus disease.
Academic Article A recombinant Hendra virus G glycoprotein subunit vaccine protects nonhuman primates against Hendra virus challenge.
Academic Article Vesicular stomatitis virus-based vaccines protect nonhuman primates against Bundibugyo ebolavirus.
Academic Article Therapeutic treatment of Nipah virus infection in nonhuman primates with a neutralizing human monoclonal antibody.
Academic Article Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAs in infected cells.
Academic Article Durability of a vesicular stomatitis virus-based marburg virus vaccine in nonhuman primates.
Academic Article Lipid nanoparticle siRNA treatment of Ebola-virus-Makona-infected nonhuman primates.
Academic Article The immunomodulating V and W proteins of Nipah virus determine disease course.
Academic Article Nipah Virus C and W Proteins Contribute to Respiratory Disease in Ferrets.
Academic Article Molecular Diagnostic Field Test for Point-of-Care Detection of Ebola Virus Directly From Blood.
Academic Article Pathogenic Differences between Nipah Virus Bangladesh and Malaysia Strains in Primates: Implications for Antibody Therapy.
Academic Article Passive Immunotherapy: Assessment of Convalescent Serum Against Ebola Virus Makona Infection in Nonhuman Primates.
Academic Article Oral and Conjunctival Exposure of Nonhuman Primates to Low Doses of Ebola Makona Virus.
Academic Article Rescue of non-human primates from advanced Sudan ebolavirus infection with lipid encapsulated siRNA.
Academic Article Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a human monoclonal antibody.
Academic Article Human-monoclonal-antibody therapy protects nonhuman primates against advanced Lassa fever.
Academic Article Transcriptome Analysis of Circulating Immune Cell Subsets Highlight the Role of Monocytes in Zaire Ebola Virus Makona Pathogenesis.
Academic Article Infection with the Makona variant results in a delayed and distinct host immune response compared to previous Ebola virus variants.
Academic Article siRNA rescues nonhuman primates from advanced Marburg and Ravn virus disease.
Academic Article Single-Dose Trivalent VesiculoVax Vaccine Protects Macaques from Lethal Ebolavirus and Marburgvirus Challenge.
Academic Article Single-dose attenuated Vesiculovax vaccines protect primates against Ebola Makona virus.
Academic Article Marburg virus infection in nonhuman primates: Therapeutic treatment by lipid-encapsulated siRNA.
Academic Article Mutual antagonism between the Ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome.
Academic Article Protection against lethal Marburg virus infection mediated by lipid encapsulated small interfering RNA.
Academic Article The Marburg virus VP24 protein interacts with Keap1 to activate the cytoprotective antioxidant response pathway.
Academic Article A recombinant vesicular stomatitis virus-based Lassa fever vaccine protects guinea pigs and macaques against challenge with geographically and genetically distinct Lassa viruses.
Academic Article Vaccination With a Highly Attenuated Recombinant Vesicular Stomatitis Virus Vector Protects Against Challenge With a Lethal Dose of Ebola Virus.
Academic Article Comparison of the Pathogenesis of the Angola and Ravn Strains of Marburg Virus in the Outbred Guinea Pig Model.
Academic Article The Synthetic Antiviral Drug Arbidol Inhibits Globally Prevalent Pathogenic Viruses.
Academic Article Single-Vector, Single-Injection Recombinant Vesicular Stomatitis Virus Vaccines Against High-Containment Viruses.
Academic Article Ebola virus vaccines - reality or fiction?
Academic Article Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins.
Academic Article Targeting Innate Immunity for Antiviral Therapy through Small Molecule Agonists of the RLR Pathway.
Academic Article Analytical Performance Characteristics of the Cepheid GeneXpert Ebola Assay for the Detection of Ebola Virus.
Academic Article Treatment of Lassa virus infection in outbred guinea pigs with first-in-class human monoclonal antibodies.
Academic Article Postexposure Efficacy of Recombinant Vesicular Stomatitis Virus Vectors Against High and Low Doses of Marburg Virus Variant Angola in Nonhuman Primates.
Academic Article Post-exposure treatments for Ebola and Marburg virus infections.
Academic Article Marburg and Ravn Viruses Fail to Cause Disease in the Domestic Ferret (Mustela putorius furo).
Academic Article A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus species in non-human primates.
Academic Article Post-exposure treatments for Ebola and Marburg virus infections.
Academic Article Efficacy of Human Monoclonal Antibody Monotherapy Against Bundibugyo Virus Infection in Nonhuman Primates.
Academic Article Author Correction: Infection with the Makona variant results in a delayed and distinct host immune response compared to previous Ebola virus variants.
Academic Article Use of Single-Injection Recombinant Vesicular Stomatitis Virus Vaccine to Protect Nonhuman Primates Against Lethal Nipah Virus Disease.
Academic Article Vesicular Stomatitis Virus-Based Vaccine Protects Mice against Crimean-Congo Hemorrhagic Fever.
Academic Article Current Ebola Virus Vaccine Progress.
Academic Article Antibody therapy for Lassa fever.
Academic Article The FDA-Approved Oral Drug Nitazoxanide Amplifies Host Antiviral Responses and Inhibits Ebola Virus.
Academic Article A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge.
Academic Article A Lethal Aerosol Exposure Model of Nipah Virus Strain Bangladesh in African Green Monkeys.
Academic Article An Intranasal Exposure Model of Lethal Nipah Virus Infection in African Green Monkeys.
Academic Article A Cross-Reactive Humanized Monoclonal Antibody Targeting Fusion Glycoprotein Function Protects Ferrets Against Lethal Nipah Virus and Hendra Virus Infection.
Academic Article Antagonism of STAT1 by Nipah virus P gene products modulates disease course but not lethal outcome in the ferret model.
Academic Article Quadrivalent VesiculoVax vaccine protects nonhuman primates from viral-induced hemorrhagic fever and death.
Academic Article Resistance of Cynomolgus Monkeys to Nipah and Hendra Virus Disease Is Associated With Cell-Mediated and Humoral Immunity.
Academic Article Immune correlates of postexposure vaccine protection against Marburg virus.
Academic Article Correction for Satterfield et al., "Nipah Virus C and W Proteins Contribute to Respiratory Disease in Ferrets".

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