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Search Results to Gareth J Morgan, PhD

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Research Expertise & Professional Interests Gareth Morgan, PhD is a Research Assistant Professor at the Boston University School of Medicine. His research focuses on the molecular mechanisms of AL amyloidosis with the aim of developing new treatments for this disease.

One or more keywords matched the following items that are connected to Morgan, Gareth

Item TypeName
Concept Amyloid
Concept Bone Diseases
Concept Carrier Proteins
Concept Disease
Concept DNA-Binding Proteins
Concept Heat-Shock Proteins
Concept Neoplasm Proteins
Concept Protein Conformation
Concept Protein Denaturation
Concept Proteins
Concept Proto-Oncogene Proteins
Concept Recombinant Proteins
Concept Protein Biosynthesis
Concept Fusion Proteins, bcr-abl
Concept Amyloid beta-Peptides
Concept Protein-Serine-Threonine Kinases
Concept Protein Structure, Secondary
Concept Protein Structure, Tertiary
Concept Protein Folding
Concept Disease Progression
Concept HSP90 Heat-Shock Proteins
Concept Escherichia coli Proteins
Concept Proto-Oncogene Proteins c-akt
Concept Protein Multimerization
Concept Protein Stability
Concept Unfolded Protein Response
Concept Protein Unfolding
Concept Protein Aggregation, Pathological
Concept Protein Aggregates
Academic Article Introduction of a (poly)histidine tag in L-lactate dehydrogenase produces a mixture of active and inactive molecules.
Academic Article Essential role of proline isomerization in stefin B tetramer formation.
Academic Article Exclusion of the native alpha-helix from the amyloid fibrils of a mixed alpha/beta protein.
Academic Article Optimizing protein stability in vivo.
Academic Article Conformational properties of the unfolded state of Im7 in nondenaturing conditions.
Academic Article Mapping local structural perturbations in the native state of stefin B (cystatin B) under amyloid forming conditions.
Academic Article Unfolded protein response activation reduces secretion and extracellular aggregation of amyloidogenic immunoglobulin light chain.
Academic Article The Kinetic Stability of a Full-Length Antibody Light Chain Dimer Determines whether Endoproteolysis Can Release Amyloidogenic Variable Domains.
Academic Article Differential Sensitivity of Target Genes to Translational Repression by miR-17~92.
Academic Article Incomplete Refolding of Antibody Light Chains to Non-Native, Protease-Sensitive Conformations Leads to Aggregation: A Mechanism of Amyloidogenesis in Patients?
Academic Article Translation efficiency is maintained at elevated temperature in Escherichia coli.
Academic Article protein folding and misfolding: Shining light by infrared spectroscopy (Fabian H, Naumann D, eds.)
Academic Article Summary: FASEB Science Research Conference on Protein Aggregation in Health and Disease.
Academic Article Role of domain interactions in the aggregation of full-length immunoglobulin light chains.
Academic Article Stabilization of amyloidogenic immunoglobulin light chains by small molecules.
Academic Article Antimyeloma activity of heat shock protein-90 inhibition.
Academic Article Essential role of caveolae in interleukin-6- and insulin-like growth factor I-triggered Akt-1-mediated survival of multiple myeloma cells.
Academic Article The Role of Protein Thermodynamics and Primary Structure in Fibrillogenesis of Variable Domains from Immunoglobulin Light Chains.
Academic Article Summary: FASEB Science Research Conference on Protein Aggregation in Health and Disease June 11-16, 2017, Steamboat Springs, Colorado, USA.
Academic Article The sialyltransferase ST3GAL6 influences homing and survival in multiple myeloma.
Academic Article Oral ixazomib maintenance following autologous stem cell transplantation (TOURMALINE-MM3): a double-blind, randomised, placebo-controlled phase 3 trial.
Academic Article Challenging the current approaches to multiple myeloma- and other cancer-related bone diseases: from bisphosphonates to targeted therapy.
Academic Article International harmonization in performing and reporting minimal residual disease assessment in multiple myeloma trials.
Academic Article The Process of Amyloid Formation due to Monoclonal Immunoglobulins.

Highlights
Search Criteria
  • Protein
  • misfolding
  • amyloid
  • diseases