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The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function.Academic Article Why?
The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI.Academic Article Why?
Ubiquitin-Protein Ligase ComplexesConcept Why?
Ubiquitin-Protein LigasesConcept Why?
Interaction of the deubiquitinating enzyme Ubp2 and the e3 ligase Rsp5 is required for transporter/receptor sorting in the multivesicular body pathway.Academic Article Why?
Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA Topoisomerase 1 inhibition.Academic Article Why?
A critical role for the E3-ligase activity of c-Cbl in VEGFR-2-mediated PLCgamma1 activation and angiogenesis.Academic Article Why?
Chitalia, VipulPerson Why?
Cohen, HerbertPerson Why?
c-Cbl, a ubiquitin E3 ligase that targets active ß-catenin: a novel layer of Wnt signaling regulation.Academic Article Why?
The E3 ligase APC/C(Cdh1) promotes ubiquitylation-mediated proteolysis of PAX3 to suppress melanocyte proliferation and melanoma growth.Academic Article Why?
Advances in the molecular basis of renal neoplasia.Academic Article Why?
AMPK downregulates ALK2 via increasing the interaction between Smurf1 and Smad6, leading to inhibition of osteogenic differentiation.Academic Article Why?
An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme.Academic Article Why?
An important von Hippel-Lindau tumor suppressor domain mediates Sp1-binding and self-association.Academic Article Why?
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