Caspase 3 | Profiles RNS

Caspase 3

"Caspase 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 9. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.

Descriptor ID	D053148
MeSH Number(s)	D08.811.277.656.262.500.126.350.300 D08.811.277.656.300.200.126.350.300 D12.644.360.075.405.350.300 D12.776.476.075.405.350.300
Concept/Terms	Caspase 3 Caspase 3 Caspase-3 Apopain CASP3 Procaspase-3 Procaspase-3 Procaspase 3 Pro-Caspase-3 Pro Caspase 3

Below are MeSH descriptors whose meaning is more general than "Caspase 3".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Peptide Hydrolases [D08.811.277.656]
Cysteine Proteases [D08.811.277.656.262]
Cysteine Endopeptidases [D08.811.277.656.262.500]
Caspases [D08.811.277.656.262.500.126]
Caspases, Effector [D08.811.277.656.262.500.126.350]
Caspase 3 [D08.811.277.656.262.500.126.350.300]
Endopeptidases [D08.811.277.656.300]
Cysteine Endopeptidases [D08.811.277.656.300.200]
Caspases [D08.811.277.656.300.200.126]
Caspases, Effector [D08.811.277.656.300.200.126.350]
Caspase 3 [D08.811.277.656.300.200.126.350.300]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Apoptosis Regulatory Proteins [D12.644.360.075]
Caspases [D12.644.360.075.405]
Caspases, Effector [D12.644.360.075.405.350]
Caspase 3 [D12.644.360.075.405.350.300]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Apoptosis Regulatory Proteins [D12.776.476.075]
Caspases [D12.776.476.075.405]
Caspases, Effector [D12.776.476.075.405.350]
Caspase 3 [D12.776.476.075.405.350.300]

Below are MeSH descriptors whose meaning is related to "Caspase 3".

Below are MeSH descriptors whose meaning is more specific than "Caspase 3".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Caspase 3" by people in this website by year, and whether "Caspase 3" was a major or minor topic of these publications.

Bar chart showing 92 publications over 22 distinct years, with a maximum of 10 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1998	0	2	2
1999	0	2	2
2000	0	4	4
2001	0	4	4
2002	0	6	6
2003	0	6	6
2004	0	10	10
2005	0	6	6
2006	0	4	4
2007	1	5	6
2008	1	3	4
2009	1	7	8
2010	0	5	5
2011	1	4	5
2012	0	2	2
2013	0	5	5
2014	0	2	2
2015	0	2	2
2016	0	3	3
2017	1	2	3
2019	0	2	2

Below are the most recent publications written about "Caspase 3" by people in Profiles.

Wang G, Sun L, Reina CP, Song I, Gabel CV, Driscoll M. CED-4 CARD domain residues can modulate non-apoptotic neuronal regeneration functions independently from apoptosis. Sci Rep. 2019 09 16; 9(1):13315. PMID: 31527664.

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Wang J, Liu Y, Liu Y, Zheng S, Wang X, Zhao J, Yang F, Zhang G, Wang C, Chen PR. Time-resolved protein activation by proximal decaging in living systems. Nature. 2019 05; 569(7757):509-513. PMID: 31068699.

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Vrselja Z, Daniele SG, Silbereis J, Talpo F, Morozov YM, Sousa AMM, Tanaka BS, Skarica M, Pletikos M, Kaur N, Zhuang ZW, Liu Z, Alkawadri R, Sinusas AJ, Latham SR, Waxman SG, Sestan N. Restoration of brain circulation and cellular functions hours post-mortem. Nature. 2019 04; 568(7752):336-343. PMID: 30996318.

View in: PubMed
Khatri N, Gilbert JP, Huo Y, Sharaflari R, Nee M, Qiao H, Man HY. The Autism Protein Ube3A/E6AP Remodels Neuronal Dendritic Arborization via Caspase-Dependent Microtubule Destabilization. J Neurosci. 2018 01 10; 38(2):363-378. PMID: 29175955.

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Wang H, Zhao YT, Zhang S, Dubielecka PM, Du J, Yano N, Chin YE, Zhuang S, Qin G, Zhao TC. Irisin plays a pivotal role to protect the heart against ischemia and reperfusion injury. J Cell Physiol. 2017 Dec; 232(12):3775-3785. PMID: 28181692.

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Kim D, Mecham RP, Trackman PC, Roy S. Downregulation of Lysyl Oxidase Protects Retinal Endothelial Cells From High Glucose-Induced Apoptosis. Invest Ophthalmol Vis Sci. 2017 May 01; 58(5):2725-2731. PMID: 28538980.

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Zhao YT, Wang H, Zhang S, Du J, Zhuang S, Zhao TC. Irisin Ameliorates Hypoxia/Reoxygenation-Induced Injury through Modulation of Histone Deacetylase 4. PLoS One. 2016; 11(11):e0166182. PMID: 27875543.

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Cea M, Cagnetta A, Acharya C, Acharya P, Tai YT, Yang C, Lovera D, Soncini D, Miglino M, Fraternali-Orcioni G, Mastracci L, Nencioni A, Montecucco F, Monacelli F, Ballestrero A, Hideshima T, Chauhan D, Gobbi M, Lemoli RM, Munshi N, Treon SP, Anderson KC. Dual NAMPT and BTK Targeting Leads to Synergistic Killing of Waldenström Macroglobulinemia Cells Regardless of MYD88 and CXCR4 Somatic Mutation Status. Clin Cancer Res. 2016 Dec 15; 22(24):6099-6109. PMID: 27287071.

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Fulciniti M, Amodio N, Bandi RL, Cagnetta A, Samur MK, Acharya C, Prabhala R, D'Aquila P, Bellizzi D, Passarino G, Adamia S, Neri A, Hunter ZR, Treon SP, Anderson KC, Tassone P, Munshi NC. miR-23b/SP1/c-myc forms a feed-forward loop supporting multiple myeloma cell growth. Blood Cancer J. 2016 Jan 15; 6:e380. PMID: 26771806.

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Miller EJ, Calamaras T, Elezaby A, Sverdlov A, Qin F, Luptak I, Wang K, Sun X, Vijay A, Croteau D, Bachschmid M, Cohen RA, Walsh K, Colucci WS. Partial Liver Kinase B1 (LKB1) Deficiency Promotes Diastolic Dysfunction, De Novo Systolic Dysfunction, Apoptosis, and Mitochondrial Dysfunction With Dietary Metabolic Challenge. J Am Heart Assoc. 2015 Dec 31; 5(1). PMID: 26722122.

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