Dendritic Spines

"Dendritic Spines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Spiny processes on DENDRITES, each of which receives excitatory input from one nerve ending (NERVE ENDINGS). They are commonly found on PURKINJE CELLS and PYRAMIDAL CELLS.

Descriptor ID	D049229
MeSH Number(s)	A08.675.256.200 A11.284.180.225.169 A11.671.240.169
Concept/Terms	Dendritic Spines Dendritic Spines Dendritic Spine Spine, Dendritic Spines, Dendritic

Below are MeSH descriptors whose meaning is more general than "Dendritic Spines".

Anatomy [A]
Nervous System [A08]
Neurons [A08.675]
Dendrites [A08.675.256]
Dendritic Spines [A08.675.256.200]
Cells [A11]
Cellular Structures [A11.284]
Cell Surface Extensions [A11.284.180]
Dendrites [A11.284.180.225]
Dendritic Spines [A11.284.180.225.169]
Neurons [A11.671]
Dendrites [A11.671.240]
Dendritic Spines [A11.671.240.169]

Below are MeSH descriptors whose meaning is related to "Dendritic Spines".

Below are MeSH descriptors whose meaning is more specific than "Dendritic Spines".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Dendritic Spines" by people in this website by year, and whether "Dendritic Spines" was a major or minor topic of these publications.

Bar chart showing 24 publications over 13 distinct years, with a maximum of 4 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	1	0	1
2006	1	0	1
2007	0	1	1
2009	1	1	2
2011	0	1	1
2012	2	2	4
2013	0	1	1
2014	1	1	2
2015	2	0	2
2016	1	1	2
2017	1	0	1
2018	1	2	3
2019	1	2	3

Below are the most recent publications written about "Dendritic Spines" by people in Profiles.

Zhang Z, Ye M, Li Q, You Y, Yu H, Ma Y, Mei L, Sun X, Wang L, Yue W, Li R, Li J, Zhang D. The Schizophrenia Susceptibility Gene OPCML Regulates Spine Maturation and Cognitive Behaviors through Eph-Cofilin Signaling. Cell Rep. 2019 Oct 01; 29(1):49-61.e7. PMID: 31577955.

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Guillamon-Vivancos T, Tyler WA, Medalla M, Chang WW, Okamoto M, Haydar TF, Luebke JI. Distinct Neocortical Progenitor Lineages Fine-tune Neuronal Diversity in a Layer-specific Manner. Cereb Cortex. 2019 03 01; 29(3):1121-1138. PMID: 29415216.

View in: PubMed
Le NTT, Wu B, Harris DA. Prion neurotoxicity. Brain Pathol. 2019 03; 29(2):263-277. PMID: 30588688.

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Fang C, Wu B, Le NTT, Imberdis T, Mercer RCC, Harris DA. Prions activate a p38 MAPK synaptotoxic signaling pathway. PLoS Pathog. 2018 09; 14(9):e1007283. PMID: 30235355.

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Goodliffe JW, Song H, Rubakovic A, Chang W, Medalla M, Weaver CM, Luebke JI. Differential changes to D1 and D2 medium spiny neurons in the 12-month-old Q175+/- mouse model of Huntington's Disease. PLoS One. 2018; 13(8):e0200626. PMID: 30118496.

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Aytan N, Choi JK, Carreras I, Crabtree L, Nguyen B, Lehar M, Blusztajn JK, Jenkins BG, Dedeoglu A. Protective effects of 7,8-dihydroxyflavone on neuropathological and neurochemical changes in a mouse model of Alzheimer's disease. Eur J Pharmacol. 2018 Jun 05; 828:9-17. PMID: 29510124.

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Viggiano D, Speranza L, Crispino M, Bellenchi GC, di Porzio U, Iemolo A, De Leonibus E, Volpicelli F, Perrone-Capano C. Information content of dendritic spines after motor learning. Behav Brain Res. 2018 Jan 15; 336:256-260. PMID: 28899819.

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Ryskamp D, Wu J, Geva M, Kusko R, Grossman I, Hayden M, Bezprozvanny I. The sigma-1 receptor mediates the beneficial effects of pridopidine in a mouse model of Huntington disease. Neurobiol Dis. 2017 Jan; 97(Pt A):46-59. PMID: 27818324.

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Fang C, Imberdis T, Garza MC, Wille H, Harris DA. A Neuronal Culture System to Detect Prion Synaptotoxicity. PLoS Pathog. 2016 May; 12(5):e1005623. PMID: 27227882.

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Paulin JJ, Haslehurst P, Fellows AD, Liu W, Jackson JD, Joel Z, Cummings DM, Edwards FA. Large and Small Dendritic Spines Serve Different Interacting Functions in Hippocampal Synaptic Plasticity and Homeostasis. Neural Plast. 2016; 2016:6170509. PMID: 26881123.

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