Pulmonary Surfactant-Associated Protein C

"Pulmonary Surfactant-Associated Protein C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

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A pulmonary surfactant associated protein that plays a role in alveolar stability by lowering the surface tension at the air-liquid interface. It is a membrane-bound protein that constitutes 1-2% of the pulmonary surfactant mass. Pulmonary surfactant-associated protein C is one of the most hydrophobic peptides yet isolated and contains an alpha-helical domain with a central poly-valine segment that binds to phospholipid bilayers.

Descriptor ID	D037721
MeSH Number(s)	D12.776.543.717 D12.776.816.750 D12.776.823.186
Concept/Terms	Pulmonary Surfactant-Associated Protein C Pulmonary Surfactant-Associated Protein C Pulmonary Surfactant Associated Protein C Surfactant Polypeptide SP-C SP-C, Surfactant Polypeptide Surfactant Polypeptide SP C SP-C protein SP C protein Pulmonary Surfactant Protein C Pulmonary Surfactant-Associated Protein SP-C Pulmonary Surfactant Associated Protein SP C

Below are MeSH descriptors whose meaning is more general than "Pulmonary Surfactant-Associated Protein C".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Pulmonary Surfactant-Associated Protein C [D12.776.543.717]
Proteolipids [D12.776.816]
Pulmonary Surfactant-Associated Protein C [D12.776.816.750]
Pulmonary Surfactant-Associated Proteins [D12.776.823]
Pulmonary Surfactant-Associated Protein C [D12.776.823.186]

Below are MeSH descriptors whose meaning is related to "Pulmonary Surfactant-Associated Protein C".

Below are MeSH descriptors whose meaning is more specific than "Pulmonary Surfactant-Associated Protein C".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Pulmonary Surfactant-Associated Protein C" by people in this website by year, and whether "Pulmonary Surfactant-Associated Protein C" was a major or minor topic of these publications.

Bar chart showing 5 publications over 3 distinct years, with a maximum of 2 publications in 2005 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	0	2	2
2012	0	1	1
2021	2	0	2

Below are the most recent publications written about "Pulmonary Surfactant-Associated Protein C" by people in Profiles.

Sun YL, Hurley K, Villacorta-Martin C, Huang J, Hinds A, Gopalan K, Caballero IS, Russo SJ, Kitzmiller JA, Whitsett JA, Beers MF, Kotton DN. Heterogeneity in Human Induced Pluripotent Stem Cell-derived Alveolar Epithelial Type II Cells Revealed with ABCA3/SFTPC Reporters. Am J Respir Cell Mol Biol. 2021 10; 65(4):442-460. PMID: 34101541.

View in: PubMed
Alysandratos KD, Russo SJ, Petcherski A, Taddeo EP, Acín-Pérez R, Villacorta-Martin C, Jean JC, Mulugeta S, Rodriguez LR, Blum BC, Hekman RM, Hix OT, Minakin K, Vedaie M, Kook S, Tilston-Lunel AM, Varelas X, Wambach JA, Cole FS, Hamvas A, Young LR, Liesa M, Emili A, Guttentag SH, Shirihai OS, Beers MF, Kotton DN. Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease. Cell Rep. 2021 08 31; 36(9):109636. PMID: 34469722.

View in: PubMed
Lee JH, Kim J, Gludish D, Roach RR, Saunders AH, Barrios J, Woo AJ, Chen H, Conner DA, Fujiwara Y, Stripp BR, Kim CF. Surfactant protein-C chromatin-bound green fluorescence protein reporter mice reveal heterogeneity of surfactant protein C-expressing lung cells. Am J Respir Cell Mol Biol. 2013 Mar; 48(3):288-98. PMID: 23204392.

View in: PubMed
Bernard ME, Kim H, Rajagopalan MS, Stone B, Salimi U, Rwigema JC, Epperly MW, Shen H, Goff JP, Franicola D, Dixon T, Cao S, Zhang X, Wang H, Stolz DB, Greenberger JS. Repopulation of the irradiation damaged lung with bone marrow-derived cells. In Vivo. 2012 Jan-Feb; 26(1):9-18. PMID: 22210711.

View in: PubMed
Chang JC, Summer R, Sun X, Fitzsimmons K, Fine A. Evidence that bone marrow cells do not contribute to the alveolar epithelium. Am J Respir Cell Mol Biol. 2005 Oct; 33(4):335-42. PMID: 15961725.

View in: PubMed
Kotton DN, Fabian AJ, Mulligan RC. Failure of bone marrow to reconstitute lung epithelium. Am J Respir Cell Mol Biol. 2005 Oct; 33(4):328-34. PMID: 15961722.

View in: PubMed

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