Diacylglycerol Kinase

"Diacylglycerol Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An enzyme of the transferase class that uses ATP to catalyze the phosphorylation of diacylglycerol to a phosphatidate. EC 2.7.1.107.

Descriptor ID	D019852
MeSH Number(s)	D08.811.913.696.620.200
Concept/Terms	Diacylglycerol Kinase Diacylglycerol Kinase Kinase, Diacylglycerol 1,2-Diacylglycerol Kinase 1,2 Diacylglycerol Kinase Kinase, 1,2-Diacylglycerol DAG Kinase Kinase, DAG Diglyceride Kinase Kinase, Diglyceride Ceramide-Diglyceride Kinase Ceramide-Diglyceride Kinase Ceramide Diglyceride Kinase Kinase, Ceramide-Diglyceride DGK-IV DGK-IV DGK beta DGK beta beta, DGK DGK delta DGK delta delta, DGK DGKdelta DGK gamma DGK gamma gamma, DGK Arachidonoyl-Diacylglycerol Kinase Arachidonoyl-Diacylglycerol Kinase Arachidonoyl Diacylglycerol Kinase Kinase, Arachidonoyl-Diacylglycerol DGK alpha DGK alpha alpha, DGK

Below are MeSH descriptors whose meaning is more general than "Diacylglycerol Kinase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Diacylglycerol Kinase [D08.811.913.696.620.200]

Below are MeSH descriptors whose meaning is more specific than "Diacylglycerol Kinase".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Diacylglycerol Kinase" by people in this website by year, and whether "Diacylglycerol Kinase" was a major or minor topic of these publications.

Bar chart showing 18 publications over 14 distinct years, with a maximum of 2 publications in 1994 and 2003 and 2005 and 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1991	0	1	1
1992	0	1	1
1994	0	2	2
1995	0	1	1
1999	1	0	1
2003	1	1	2
2004	1	0	1
2005	2	0	2
2006	1	0	1
2007	1	0	1
2008	0	1	1
2009	0	1	1
2012	1	1	2
2013	1	0	1

Below are the most recent publications written about "Diacylglycerol Kinase" by people in Profiles.

Batista EL, Kantarci AI, Hasturk H, Van Dyke TE. Alternative splicing generates a diacylglycerol kinase a transcript that acts as a dominant-negative modulator of superoxide production in localized aggressive periodontitis. J Periodontol. 2014 Jul; 85(7):934-43. PMID: 24171497.

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Bae-Harboe YS, Park HY. Tyrosinase: a central regulatory protein for cutaneous pigmentation. J Invest Dermatol. 2012 Dec; 132(12):2678-80. PMID: 23187110.

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Saadeh M, Ferrante TC, Kane A, Shirihai O, Corkey BE, Deeney JT. Reactive oxygen species stimulate insulin secretion in rat pancreatic islets: studies using mono-oleoyl-glycerol. PLoS One. 2012; 7(1):e30200. PMID: 22272304.

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Laramie JM, Wilk JB, Williamson SL, Nagle MW, Latourelle JC, Tobin JE, Province MA, Borecki IB, Myers RH. Multiple genes influence BMI on chromosome 7q31-34: the NHLBI Family Heart Study. Obesity (Silver Spring). 2009 Dec; 17(12):2182-9. PMID: 19461589.

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Pankratz N, Wilk JB, Latourelle JC, DeStefano AL, Halter C, Pugh EW, Doheny KF, Gusella JF, Nichols WC, Foroud T, Myers RH. Genomewide association study for susceptibility genes contributing to familial Parkinson disease. Hum Genet. 2009 Jan; 124(6):593-605. PMID: 18985386.

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Leach NT, Sun Y, Michaud S, Zheng Y, Ligon KL, Ligon AH, Sander T, Korf BR, Lu W, Harris DJ, Gusella JF, Maas RL, Quade BJ, Cole AJ, Kelz MB, Morton CC. Disruption of diacylglycerol kinase delta (DGKD) associated with seizures in humans and mice. Am J Hum Genet. 2007 Apr; 80(4):792-9. PMID: 17357084.

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Biron D, Shibuya M, Gabel C, Wasserman SM, Clark DA, Brown A, Sengupta P, Samuel AD. A diacylglycerol kinase modulates long-term thermotactic behavioral plasticity in C. elegans. Nat Neurosci. 2006 Dec; 9(12):1499-505. PMID: 17086178.

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Yahagi H, Takeda M, Asaumi Y, Okumura K, Takahashi R, Takahashi J, Ohta J, Tada H, Minatoya Y, Sakuma M, Watanabe J, Goto K, Shirato K, Kagaya Y. Differential regulation of diacylglycerol kinase isozymes in cardiac hypertrophy. Biochem Biophys Res Commun. 2005 Jun 24; 332(1):101-8. PMID: 15896305.

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Batista EL, Warbington M, Badwey JA, Van Dyke TE. Differentiation of HL-60 cells to granulocytes involves regulation of select diacylglycerol kinases (DGKs). J Cell Biochem. 2005 Mar 1; 94(4):774-93. PMID: 15578578.

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Gronert K, Kantarci A, Levy BD, Clish CB, Odparlik S, Hasturk H, Badwey JA, Colgan SP, Van Dyke TE, Serhan CN. A molecular defect in intracellular lipid signaling in human neutrophils in localized aggressive periodontal tissue damage. J Immunol. 2004 Feb 1; 172(3):1856-61. PMID: 14734770.

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