Molecular Chaperones

"Molecular Chaperones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of cellular proteins that mediate the correct assembly or disassembly of polypeptides and their associated ligands. Although they take part in the assembly process, molecular chaperones are not components of the final structures.

Descriptor ID	D018832
MeSH Number(s)	D12.776.580
Concept/Terms	Molecular Chaperones Molecular Chaperones Molecular Chaperone Chaperone, Molecular Chaperones, Molecular

Below are MeSH descriptors whose meaning is more general than "Molecular Chaperones".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Molecular Chaperones [D12.776.580]

Below are MeSH descriptors whose meaning is related to "Molecular Chaperones".

Below are MeSH descriptors whose meaning is more specific than "Molecular Chaperones".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Molecular Chaperones" by people in this website by year, and whether "Molecular Chaperones" was a major or minor topic of these publications.

Bar chart showing 71 publications over 24 distinct years, with a maximum of 8 publications in 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	1	3
1997	1	0	1
1998	1	1	2
1999	2	1	3
2000	2	0	2
2001	3	1	4
2002	3	1	4
2003	2	1	3
2004	1	4	5
2005	5	1	6
2006	0	1	1
2007	5	3	8
2008	1	0	1
2009	2	2	4
2010	1	1	2
2011	1	2	3
2012	3	0	3
2013	1	2	3
2014	1	2	3
2015	2	0	2
2016	1	0	1
2017	1	2	3
2018	2	0	2
2019	1	1	2

Below are the most recent publications written about "Molecular Chaperones" by people in Profiles.

Esteve-Bruna D, Carrasco-López C, Blanco-Touriñán N, Iserte J, Calleja-Cabrera J, Perea-Resa C, Úrbez C, Carrasco P, Yanovsky MJ, Blázquez MA, Salinas J, Alabadí D. Prefoldins contribute to maintaining the levels of the spliceosome LSM2-8 complex through Hsp90 in Arabidopsis. Nucleic Acids Res. 2020 06 19; 48(11):6280-6293. PMID: 32396196.

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O'Meara TR, O'Meara MJ, Polvi EJ, Pourhaghighi MR, Liston SD, Lin ZY, Veri AO, Emili A, Gingras AC, Cowen LE. Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a fungal pathogen. PLoS Biol. 2019 07; 17(7):e3000358. PMID: 31283755.

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Whitesell L, Robbins N, Huang DS, McLellan CA, Shekhar-Guturja T, LeBlanc EV, Nation CS, Hui R, Hutchinson A, Collins C, Chatterjee S, Trilles R, Xie JL, Krysan DJ, Lindquist S, Porco JA, Tatu U, Brown LE, Pizarro J, Cowen LE. Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus. Nat Commun. 2019 01 24; 10(1):402. PMID: 30679438.

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Qamar S, Wang G, Randle SJ, Ruggeri FS, Varela JA, Lin JQ, Phillips EC, Miyashita A, Williams D, Ströhl F, Meadows W, Ferry R, Dardov VJ, Tartaglia GG, Farrer LA, Kaminski Schierle GS, Kaminski CF, Holt CE, Fraser PE, Schmitt-Ulms G, Klenerman D, Knowles T, Vendruscolo M, St George-Hyslop P. FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-p Interactions. Cell. 2018 04 19; 173(3):720-734.e15. PMID: 29677515.

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Lang BJ, Holton KM, Gong J, Calderwood SK. A Workflow Guide to RNA-seq Analysis of Chaperone Function and Beyond. Methods Mol Biol. 2018; 1709:233-252. PMID: 29177664.

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Sánchez-Morgan N, Kirsch KH, Trackman PC, Sonenshein GE. UXT Is a LOX-PP Interacting Protein That Modulates Estrogen Receptor Alpha Activity in Breast Cancer Cells. J Cell Biochem. 2017 Aug; 118(8):2347-2356. PMID: 28106301.

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Perea-Resa C, Rodríguez-Milla MA, Iniesto E, Rubio V, Salinas J. Prefoldins Negatively Regulate Cold Acclimation in Arabidopsis thaliana by Promoting Nuclear Proteasome-Mediated HY5 Degradation. Mol Plant. 2017 06 05; 10(6):791-804. PMID: 28412546.

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Melentijevic I, Toth ML, Arnold ML, Guasp RJ, Harinath G, Nguyen KC, Taub D, Parker JA, Neri C, Gabel CV, Hall DH, Driscoll M. C. elegans neurons jettison protein aggregates and mitochondria under neurotoxic stress. Nature. 2017 02 16; 542(7641):367-371. PMID: 28178240.

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Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK, Cruchaga C, De Jager P, Ertekin-Taner N, Evans D, Fallin MD, Foroud TM, Friedland RP, Goate AM, Graff-Radford NR, Hendrie H, Hall KS, Hamilton-Nelson KL, Inzelberg R, Kamboh MI, Kauwe JSK, Kukull WA, Kunkle BW, Kuwano R, Larson EB, Logue MW, Manly JJ, Martin ER, Montine TJ, Mukherjee S, Naj A, Reiman EM, Reitz C, Sherva R, St George-Hyslop PH, Thornton T, Younkin SG, Vardarajan BN, Wang LS, Wendlund JR, Winslow AR, Haines J, Mayeux R, Pericak-Vance MA, Schellenberg G, Lunetta KL, Farrer LA. Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimers Dement. 2017 Jul; 13(7):727-738. PMID: 28183528.

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Grillet M, Dominguez Gonzalez B, Sicart A, Pöttler M, Cascalho A, Billion K, Hernandez Diaz S, Swerts J, Naismith TV, Gounko NV, Verstreken P, Hanson PI, Goodchild RE. Torsins Are Essential Regulators of Cellular Lipid Metabolism. Dev Cell. 2016 08 08; 38(3):235-47. PMID: 27453503.

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