Rhodopsin | Profiles RNS

Rhodopsin

"Rhodopsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A purplish-red, light-sensitive pigment found in RETINAL ROD CELLS of most vertebrates. It is a complex consisting of a molecule of ROD OPSIN and a molecule of 11-cis retinal (RETINALDEHYDE). Rhodopsin exhibits peak absorption wavelength at about 500 nm.

Descriptor ID	D012243
MeSH Number(s)	D12.776.543.750.100.955 D23.767.930.750.500.500
Concept/Terms	Rhodopsin Rhodopsin Visual Purple

Below are MeSH descriptors whose meaning is more general than "Rhodopsin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, G-Protein-Coupled [D12.776.543.750.100]
Rhodopsin [D12.776.543.750.100.955]
Biological Factors [D23]
Pigments, Biological [D23.767]
Retinal Pigments [D23.767.930]
Opsins [D23.767.930.750]
Rod Opsins [D23.767.930.750.500]
Rhodopsin [D23.767.930.750.500.500]

Below are MeSH descriptors whose meaning is related to "Rhodopsin".

Below are MeSH descriptors whose meaning is more specific than "Rhodopsin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Rhodopsin" by people in this website by year, and whether "Rhodopsin" was a major or minor topic of these publications.

Bar chart showing 49 publications over 28 distinct years, with a maximum of 5 publications in 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1982	0	1	1
1983	1	3	4
1987	1	0	1
1988	0	1	1
1990	1	0	1
1994	1	1	2
1995	1	0	1
1996	1	0	1
1997	0	1	1
1999	1	0	1
2000	0	1	1
2001	2	1	3
2002	0	1	1
2003	1	1	2
2004	1	1	2
2005	2	0	2
2006	0	5	5
2007	1	0	1
2008	1	0	1
2009	2	1	3
2010	1	0	1
2011	1	1	2
2012	1	3	4
2014	0	2	2
2015	0	1	1
2016	1	1	2
2019	0	1	1
2020	1	0	1

Below are the most recent publications written about "Rhodopsin" by people in Profiles.

Caruso G, Klaus CJ, Hamm HE, Gurevich VV, Makino CL, DiBenedetto E. Position of rhodopsin photoisomerization on the disk surface confers variability to the rising phase of the single photon response in vertebrate rod photoreceptors. PLoS One. 2020; 15(10):e0240527. PMID: 33052986.

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Yue WWS, Silverman D, Ren X, Frederiksen R, Sakai K, Yamashita T, Shichida Y, Cornwall MC, Chen J, Yau KW. Elementary response triggered by transducin in retinal rods. Proc Natl Acad Sci U S A. 2019 03 12; 116(11):5144-5153. PMID: 30796193.

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Athanasiou D, Aguila M, Opefi CA, South K, Bellingham J, Bevilacqua D, Munro PM, Kanuga N, Mackenzie FE, Dubis AM, Georgiadis A, Graca AB, Pearson RA, Ali RR, Sakami S, Palczewski K, Sherman MY, Reeves PJ, Cheetham ME. Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration. Hum Mol Genet. 2017 Jan 15; 26(2):305-319. PMID: 28065882.

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Frederiksen R, Nymark S, Kolesnikov AV, Berry JD, Adler L, Koutalos Y, Kefalov VJ, Cornwall MC. Rhodopsin kinase and arrestin binding control the decay of photoactivated rhodopsin and dark adaptation of mouse rods. J Gen Physiol. 2016 Jul; 148(1):1-11. PMID: 27353443.

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Berry J, Frederiksen R, Yao Y, Nymark S, Chen J, Cornwall C. Effect of Rhodopsin Phosphorylation on Dark Adaptation in Mouse Rods. J Neurosci. 2016 Jun 29; 36(26):6973-87. PMID: 27358455.

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Kondabolu K, Kowalski MM, Roberts EA, Han X. Optogenetics and deep brain stimulation neurotechnologies. Handb Exp Pharmacol. 2015; 228:441-50. PMID: 25977092.

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Sun L, Shay J, McLoed M, Roodhouse K, Chung SH, Clark CM, Pirri JK, Alkema MJ, Gabel CV. Neuronal regeneration in C. elegans requires subcellular calcium release by ryanodine receptor channels and can be enhanced by optogenetic stimulation. J Neurosci. 2014 Nov 26; 34(48):15947-56. PMID: 25429136.

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Wang JS, Nymark S, Frederiksen R, Estevez ME, Shen SQ, Corbo JC, Cornwall MC, Kefalov VJ. Chromophore supply rate-limits mammalian photoreceptor dark adaptation. J Neurosci. 2014 Aug 20; 34(34):11212-21. PMID: 25143602.

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Han X. In vivo application of optogenetics for neural circuit analysis. ACS Chem Neurosci. 2012 Aug 15; 3(8):577-84. PMID: 22896801.

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Makino CL, Wen XH, Michaud NA, Covington HI, DiBenedetto E, Hamm HE, Lem J, Caruso G. Rhodopsin expression level affects rod outer segment morphology and photoresponse kinetics. PLoS One. 2012; 7(5):e37832. PMID: 22662234.

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