Proto-Oncogene Proteins

"Proto-Oncogene Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.

Descriptor ID	D011518
MeSH Number(s)	D12.776.624.664.700
Concept/Terms	Proto-Oncogene Proteins Proto-Oncogene Proteins Proto Oncogene Proteins Proto-Oncogene Products, Cellular Cellular Proto-Oncogene Products Proto Oncogene Products, Cellular Proto Oncogene Proteins, Cellular c-onc Proteins c onc Proteins Cellular Proto-Oncogene Proteins Cellular Proto Oncogene Proteins Proto-Oncogene Proteins, Cellular

Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Neoplasm Proteins [D12.776.624]
Oncogene Proteins [D12.776.624.664]
Proto-Oncogene Proteins [D12.776.624.664.700]

Below are MeSH descriptors whose meaning is related to "Proto-Oncogene Proteins".

Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Proto-Oncogene Proteins" by people in this website by year, and whether "Proto-Oncogene Proteins" was a major or minor topic of these publications.

Bar chart showing 309 publications over 35 distinct years, with a maximum of 28 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1988	1	0	1
1989	1	1	2
1990	1	5	6
1991	5	1	6
1992	1	0	1
1993	6	1	7
1994	2	3	5
1995	1	1	2
1996	4	3	7
1997	6	3	9
1998	7	2	9
1999	9	2	11
2000	9	6	15
2001	7	10	17
2002	13	11	24
2003	13	7	20
2004	17	11	28
2005	12	9	21
2006	6	0	6
2007	2	1	3
2008	2	7	9
2009	6	5	11
2010	5	4	9
2011	9	3	12
2012	2	6	8
2013	2	2	4
2014	4	6	10
2015	6	5	11
2016	6	2	8
2017	3	2	5
2018	5	2	7
2019	1	1	2
2020	4	3	7
2021	3	2	5
2022	0	1	1

Below are the most recent publications written about "Proto-Oncogene Proteins" by people in Profiles.

Bam M, Yang X, Ginsberg JP, Aiello AE, Uddin M, Galea S, Nagarkatti PS, Nagarkatti M. Long non-coding RNA LINC00926 regulates WNT10B signaling pathway thereby altering inflammatory gene expression in PTSD. Transl Psychiatry. 2022 May 12; 12(1):200. PMID: 35551428.

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Tabib T, Huang M, Morse N, Papazoglou A, Behera R, Jia M, Bulik M, Monier DE, Benos PV, Chen W, Domsic R, Lafyatis R. Myofibroblast transcriptome indicates SFRP2hi fibroblast progenitors in systemic sclerosis skin. Nat Commun. 2021 07 19; 12(1):4384. PMID: 34282151.

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Pal-Ghosh R, Xue D, Warburton R, Hill N, Polgar P, Wilson JL. CDC2 Is an Important Driver of Vascular Smooth Muscle Cell Proliferation via FOXM1 and PLK1 in Pulmonary Arterial Hypertension. Int J Mol Sci. 2021 Jun 28; 22(13). PMID: 34203295.

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Halperin RF, Hegde A, Lang JD, Raupach EA, Legendre C, Liang WS, LoRusso PM, Sekulic A, Sosman JA, Trent JM, Rangasamy S, Pirrotte P, Schork NJ. Improved methods for RNAseq-based alternative splicing analysis. Sci Rep. 2021 05 24; 11(1):10740. PMID: 34031440.

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Olesinski EA, Bhatt S. Dynamic BH3 profiling method for rapid identification of active therapy in BH3 mimetics resistant xenograft mouse models. STAR Protoc. 2021 06 18; 2(2):100461. PMID: 34027474.

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Ko HJ, Tsai CY, Chiou SJ, Lai YL, Wang CH, Cheng JT, Chuang TH, Huang CF, Kwan AL, Loh JK, Hong YR. The Phosphorylation Status of Drp1-Ser637 by PKA in Mitochondrial Fission Modulates Mitophagy via PINK1/Parkin to Exert Multipolar Spindles Assembly during Mitosis. Biomolecules. 2021 03 13; 11(3). PMID: 33805672.

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Evans MA, Sano S, Walsh K. Clonal haematopoiesis and cardiovascular disease: how low can you go? Eur Heart J. 2021 01 20; 42(3):266-268. PMID: 33313787.

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Bhatt S, Pioso MS, Olesinski EA, Yilma B, Ryan JA, Mashaka T, Leutz B, Adamia S, Zhu H, Kuang Y, Mogili A, Louissaint A, Bohl SR, Kim AS, Mehta AK, Sanghavi S, Wang Y, Morris E, Halilovic E, Paweletz CP, Weinstock DM, Garcia JS, Letai A. Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia. Cancer Cell. 2020 12 14; 38(6):872-890.e6. PMID: 33217342.

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Lee ES, Wolf EJ, Ihn SSJ, Smith HW, Emili A, Palazzo AF. TPR is required for the efficient nuclear export of mRNAs and lncRNAs from short and intron-poor genes. Nucleic Acids Res. 2020 11 18; 48(20):11645-11663. PMID: 33091126.

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Bao EL, Nandakumar SK, Liao X, Bick AG, Karjalainen J, Tabaka M, Gan OI, Havulinna AS, Kiiskinen TTJ, Lareau CA, de Lapuente Portilla AL, Li B, Emdin C, Codd V, Nelson CP, Walker CJ, Churchhouse C, de la Chapelle A, Klein DE, Nilsson B, Wilson PWF, Cho K, Pyarajan S, Gaziano JM, Samani NJ, Regev A, Palotie A, Neale BM, Dick JE, Natarajan P, O'Donnell CJ, Daly MJ, Milyavsky M, Kathiresan S, Sankaran VG. Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells. Nature. 2020 10; 586(7831):769-775. PMID: 33057200.

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