Zhi-Xiong Xiao, PhD
Adjunct Professor
Boston University School of Medicine
Dept of Biochemistry

PhD, University of Massachusetts Amherst
MS, Sichuan University

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences

Regulation of Retinoblastoma Protein by Prolyl Isomerase Pin1
03/15/2005 - 04/14/2008 (Dept Sponsor)
Department of Defense/Army

Regulation of p53 in Response to Genotoxic Stress
08/01/2003 - 07/31/2007 (PI)
NIH/National Institute of General Medical Sciences
5 R01 GM70017 04

Determination of Oncogenicity and Tumorigenecity of Avian Adenoviral Gene GAM1
05/10/2006 - 05/10/2007 (PI)
GlaxoSmithKline, Inc.

Functional Screening For Genom
01/31/1999 - 12/31/2002 (PI)

Mechanisms Of Environmental
09/30/1998 - 05/31/2002 (PI)
US Army

P818 Damd179717311 10/30/
06/01/1999 - 09/30/2000 (PI)
Dept of the Army

S929 Sub Bonrc 9/29/98
06/01/1999 - 09/30/2000 (PI)

M857 Acs 6/30/98
06/01/1999 - 09/30/2000 (PI)
American Cancer Soc

Function Of Mdm2 Rb
07/01/1999 - 04/30/2000 (PI)
1 R01 CA79804-01A1


Yr Title Project-Sub Proj Pubs
2011 REGULATION AND FUNCTION OF P63 5P41RR010888-15-5141 259
2010 REGULATION AND FUNCTION OF P63 5P41RR010888-14-6846 259
2010 Role of MDM2 in Cell Proliferation and Tumorigenesis 5R01CA079804-09 15
2009 REGULATION AND FUNCTION OF P63 5P41RR010888-13-6203 259
2009 Role of MDM2 in Cell Proliferation and Tumorigenesis 5R01CA079804-08 15
2008 REGULATION AND FUNCTION OF P63 5P41RR010888-12-5305 259
2008 Role of MDM2 in Cell Proliferation and Tumorigenesis 5R01CA079804-07 15
2007 REGULATION AND FUNCTION OF P63 2P41RR010888-11-8126 259
2007 Role of MDM2 in Cell Proliferation and Tumorigenesis 2R01CA079804-06A2 15
2006 Regulation of p53 in reespnse to genotoxic stress 5R01GM070017-04 7
Showing 10 of 19 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Fei Q, Shang K, Zhang J, Chuai S, Kong D, Zhou T, Fu S, Liang Y, Li C, Chen Z, Zhao Y, Yu Z, Huang Z, Hu M, Ying H, Chen Z, Zhang Y, Xing F, Zhu J, Xu H, Zhao K, Lu C, Atadja P, Xiao ZX, Li E, Shou J. Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53. Nat Commun. 2015; 6:8651. PMID: 26471002; DOI: 10.1038/ncomms9651;
  2. Yuan L, Lv Y, Li H, Gao H, Song S, Zhang Y, Xing G, Kong X, Wang L, Li Y, Zhou T, Gao D, Xiao ZX, Yin Y, Wei W, He F, Zhang L. Deubiquitylase OTUD3 regulates PTEN stability and suppresses tumorigenesis. Nat Cell Biol. 2015 Sep; 17(9):1169-81. PMID: 26280536; DOI: 10.1038/ncb3218;
  3. Walsh EM, Niu M, Bergholz J, Xiao ZX. Nutlin-3 down-regulates retinoblastoma protein expression and inhibits muscle cell differentiation. Biochem Biophys Res Commun. 2015 May 29; 461(2):293-9. PMID: 25871794; PMCID: PMC4454893; DOI: 10.1016/j.bbrc.2015.04.024;
  4. Zhang H, Hu L, Qiu W, Deng T, Zhang Y, Bergholz J, Xiao ZX. MDMX exerts its oncogenic activity via suppression of retinoblastoma protein. Oncogene. 2015 Oct 29; 34(44):5560-9. PMID: 25703327; DOI: 10.1038/onc.2015.11;
  5. Tong Y, Ying H, Liu R, Li L, Bergholz J, Xiao ZX. Pin1 inhibits PP2A-mediated Rb dephosphorylation in regulation of cell cycle and S-phase DNA damage. Cell Death Dis. 2015; 6:e1640. PMID: 25675300; PMCID: PMC4669794; DOI: 10.1038/cddis.2015.3;
  6. Yuan L, Chen Z, Song S, Wang S, Tian C, Xing G, Chen X, Xiao ZX, He F, Zhang L. p53 degradation by a coronavirus papain-like protease suppresses type I interferon signaling. J Biol Chem. 2015 Jan 30; 290(5):3172-82. PMID: 25505178; PMCID: PMC4317044; DOI: 10.1074/jbc.M114.619890;
  7. Xiang X, Deng L, Zhang J, Zhang X, Lei T, Luan G, Yang C, Xiao ZX, Li Q, Li Q. A distinct expression pattern of cyclin K in mammalian testes suggests a functional role in spermatogenesis. PLoS One. 2014; 9(7):e101539. PMID: 25004108; PMCID: PMC4086901; DOI: 10.1371/journal.pone.0101539;
  8. Wu J, Liang S, Bergholz J, He H, Walsh EM, Zhang Y, Xiao ZX. ?Np63a activates CD82 metastasis suppressor to inhibit cancer cell invasion. Cell Death Dis. 2014; 5:e1280. PMID: 24901051; PMCID: PMC4611714; DOI: 10.1038/cddis.2014.239;
  9. Tran D, Bergholz J, Zhang H, He H, Wang Y, Zhang Y, Li Q, Kirkland JL, Xiao ZX. Insulin-like growth factor-1 regulates the SIRT1-p53 pathway in cellular senescence. Aging Cell. 2014 Aug; 13(4):669-78. PMID: 25070626; PMCID: PMC4118446; DOI: 10.1111/acel.12219;
  10. Dai Q, Luan G, Deng L, Lei T, Kang H, Song X, Zhang Y, Xiao ZX, Li Q. Primordial dwarfism gene maintains Lin28 expression to safeguard embryonic stem cells from premature differentiation. Cell Rep. 2014 May 8; 7(3):735-46. PMID: 24768001; DOI: 10.1016/j.celrep.2014.03.053;
Showing 10 of 45 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 45 publications over 20 distinct years, with a maximum of 6 publications in 2014


In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Cell cycle
cell migration
cell death
signal transduction
cancer biology
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