Yiqin (“E-chin”) Xiong

Yiqin (“E-chin”) Xiong, MD, PhD

Assistant Professor

Boston University Chobanian & Avedisian School of Medicine

Pathology & Laboratory Medicine

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Dr. Yiqin Xiong is an Assistant Professor of Pathology & Laboratory Medicine at Boston University Chobanian & Avedisian School of Medicine and an Attending Pathologist at Boston Medical Center. She earned her Medical Doctorate (MD) from Shandong Medical University, China, a Master of Science in Physiology from Shandong University, and a PhD in Neurobiology from the University of Kentucky. Dr. Xiong completed her Anatomic and Clinical Pathology residency at the University of Massachusetts, Worcester, and a Gastrointestinal Pathology fellowship at the Icahn School of Medicine at Mount Sinai, New York.

Dr. Xiong’s clinical expertise focuses on gastrointestinal and genitourinary pathology, with a commitment to precise diagnosis and patient care. Her research explores molecular mechanisms in cancer and inflammatory diseases, with over 20 peer-reviewed publications in journals such as Nature, Proceedings of the National Academy of Sciences, and Human Pathology. Her work on topics like gastric carcinoma and psoriasis has been supported by grants, including an NCI U01, and recognized with awards such as the American Heart Association Postdoctoral Fellowship and the Association of Molecular Pathology Best Poster Travel Award.

A dedicated educator, Dr. Xiong serves as the Resident GI Rotation Director and mentors pathology trainees. She is actively involved in professional organizations, including the College of American Pathologists, United States and Canadian Academy of Pathology, and Gastrointestinal Pathology Association, and reviews for journals like American Journal of Clinical Pathology.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Choi A, Alzayadneh E, Breheny P, Xiong Y. Clinical, Endoscopic, and Upper Gastrointestinal Histological Manifestations in Pediatric Inflammatory Bowel Disease: Insights from a Large Cohort. Pediatr Dev Pathol. 2026; 29(2):112-119. PMID: 41473946; DOI: 10.1177/10935266251404114;

Avellino A, Jiang X, Lee M, Yu J, Liu S, Han X, Li J, Shilyansky J, Wang Z, Curry M, Xiong Y, Lizarraga IM, Huang Y, Sugg SL, Hao J, Li B. An Olive Oil-Based High-Fat Diet Promotes Obesity-Driven Metastasis of Triple-Negative Breast Cancer. Cancer Res. 2025 Dec 15; 85(24):5015-5032. PMID: 40911782; PMCID: PMC12502211; DOI: 10.1158/0008-5472.CAN-25-0822;

Wang Y, Gao JZ, Gurung P, Short SP, Xiong Y, Canna SW, Kang Z. An animal model of NLRC4-associated autoinflammation and infantile enterocolitis reveals novel therapeutic strategies. Cell Mol Immunol. 2025 Dec; 22(12):1567-1580. PMID: 41116055; PMCID: PMC12660311; DOI: 10.1038/s41423-025-01355-x;

Kahveci AS, Aslam A, Xiong Y, Tanaka T. De-Novo Hepatic Angiosarcoma in a Liver Transplant Recipient. Transplant Proc. 2025 Sep; 57(7):1348-1351. PMID: 40287304; DOI: 10.1016/j.transproceed.2025.03.031;

Brechtel L, Orzel J, Xiong Y, Vollstedt A. Transvaginal partial excision of a circumferential urethral leiomyoma: Surgical technique and outcome. Urol Case Rep. 2025 Jul; 61:103049. PMID: 40950797; PMCID: PMC12432835; DOI: 10.1016/j.eucr.2025.103049;

Jiang X, Xiong Y, Yu J, Avellino A, Liu S, Han X, Wang Z, Shilyansky JS, Curry MA, Hao J, Sauter ER, Huang Y, Sugg SL, Li B. Expression profiles of FABP4 and FABP5 in breast cancer: clinical implications and perspectives. Discov Oncol. 2025 Mar 19; 16(1):357. PMID: 40106183; PMCID: PMC11923334; DOI: 10.1007/s12672-025-02117-x;

Yorek M, Jiang X, Liu S, Hao J, Yu J, Avellino A, Liu Z, Curry M, Keen H, Shao J, Kanagasabapathy A, Kong M, Xiong Y, Sauter ER, Sugg SL, Li B. FABP4-mediated lipid accumulation and lipolysis in tumor-associated macrophages promote breast cancer metastasis. Elife. 2024 Nov 08; 13. PMID: 39513934; PMCID: PMC11548877; DOI: 10.7554/eLife.101221;

Holt C, Elliott DE, Xiong Y. Giant inflammatory polyposis in Crohn's disease mimicking recurrent obstructing colon cancer. Pathol Int. 2024 Oct; 74(10):618-620. PMID: 39254479; DOI: 10.1111/pin.13479;

Wang Y, Gao JZ, Sakaguchi T, Maretzky T, Gurung P, Narayanan NS, Short S, Xiong Y, Kang Z. LRRK2 G2019S Promotes Colon Cancer Potentially via LRRK2-GSDMD Axis-Mediated Gut Inflammation. Cells. 2024 Mar 23; 13(7). PMID: 38607004; PMCID: PMC11011703; DOI: 10.3390/cells13070565;

Hao J, Yu J, Yorek MS, Yu CL, Pope RM, Chimenti MS, Xiong Y, Klingelhutz A, Jabbari A, Li B. Keratinocyte FABP5-VCP complex mediates recruitment of neutrophils in psoriasis. Cell Rep. 2023 Nov 28; 42(11):113449. PMID: 37967009; PMCID: PMC10729729; DOI: 10.1016/j.celrep.2023.113449;

Showing 10 of 36 results. Show More

Durham K, Zhang X, Xiong Y, Reddy A, Polyak S. Plaque-Like Lesions in the Gastrointestinal Tract. ACG Case Rep J. 2023 Aug; 10(8):e01115. PMID: 37539376; PMCID: PMC10396333; DOI: 10.14309/crj.0000000000001115;

Liang Y, Khandakar B, Hao Y, Xiong Y, Liu BL, Zhang X. Histology and clinical correlations in autoimmune hepatitis, primary biliary cholangitis, and autoimmune hepatitis-primary biliary cholangitis overlap syndrome. Ann Diagn Pathol. 2023 Dec; 67:152178. PMID: 37468373; DOI: 10.1016/j.anndiagpath.2023.152178;

Choi A, Findlay S, Xiong Y. Large Perianal Tailgut Cyst with Invasive Squamous Cell Carcinoma and Low-Grade Mucinous Neoplasm. J Gastrointest Surg. 2023 Nov; 27(11):2701-2703. PMID: 37369966; DOI: 10.1007/s11605-023-05763-0;

Liang Y, Hao Y, Xiong Y, Zhong M, Jain D. MYC overexpression in inflammatory bowel disease-associated conventional dysplasia and association of subsequent low-grade dysplasia in follow-up biopsies. Pathol Res Pract. 2023 Aug; 248:154642. PMID: 37379711; DOI: 10.1016/j.prp.2023.154642;

Hao Y, Liu BL, Liang Y, Xiong Y, Polydorides AD, Ward S. Further prognostic stratification of intestinal type of gastric adenocarcinoma by CDX2 expression pattern. Hum Pathol. 2023 Jan; 131:61-67. PMID: 36403867; DOI: 10.1016/j.humpath.2022.11.005;

Gangadharan Nambiar G, Rahhal R, Davis BP, Xiong Y, Cheung D. Refractory Pediatric Fibrostenotic Eosinophilic Esophagitis Treated With Dupilumab. ACG Case Rep J. 2022 Nov; 9(11):e00887. PMID: 36382335; PMCID: PMC9663132; DOI: 10.14309/crj.0000000000000887;

Zong Y, Xiong Y, Dresser K, Yang M, Bledsoe JR. Polyclonal PAX8 expression in carcinomas of the biliary tract - Frequent non-specific staining represents a potential diagnostic pitfall. Ann Diagn Pathol. 2021 Aug; 53:151762. PMID: 34102541; DOI: 10.1016/j.anndiagpath.2021.151762;

Xiong Y, Dresser K, Cornejo KM. Frequent TLE1 Expression in Cutaneous Neoplasms. Am J Dermatopathol. 2019 Jan; 41(1):1-6. PMID: 30608261; DOI: 10.1097/DAD.0000000000001186;

Lewandrowski K, Keegan A, Makarenko V, Maryamchak E, Mata DA, Palte MJ, Rudolf JW, Safdar N, Schmidt RJ, Stuart L, Xiong Y, Rao L, Melanson SEF, Michael Snyder L. Development of a Commercial Reference Laboratory Elective Rotation for Residents in Clinical Pathology. Am J Clin Pathol. 2018 Oct 24; 150(6):485-490. PMID: 30053105; DOI: 10.1093/ajcp/aqy070;

Morrell TJ, Xiong Y, Deng A, Dresser K, O'Donnell P, Cornejo KM. Expression of TLE1 in Malignant Melanoma With Spindle Cell Morphology: A Potential Diagnostic Pitfall. Int J Surg Pathol. 2019 May; 27(3):259-262. PMID: 30301396; DOI: 10.1177/1066896918805137;

Salhab M, Migdady Y, Donahue M, Xiong Y, Dresser K, Walsh W, Chen BJ, Liebmann J. Immunohistochemical expression and prognostic value of PD-L1 in Extrapulmonary small cell carcinoma: a single institution experience. J Immunother Cancer. 2018 May 29; 6(1):42. PMID: 29843803; PMCID: PMC5975459; DOI: 10.1186/s40425-018-0359-1;

Xiong Y, Marshall C, Yang M. Complete Appendiceal Intussusception Associated with Endometriosis. J Gastrointest Surg. 2019 Jan; 23(1):179-180. PMID: 29766445; DOI: 10.1007/s11605-018-3803-0;

Han P, Li W, Yang J, Shang C, Lin CH, Cheng W, Hang CT, Cheng HL, Chen CH, Wong J, Xiong Y, Zhao M, Drakos SG, Ghetti A, Li DY, Bernstein D, Chen HS, Quertermous T, Chang CP. Epigenetic response to environmental stress: Assembly of BRG1-G9a/GLP-DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts. Biochim Biophys Acta. 2016 Jul; 1863(7 Pt B):1772-81. PMID: 26952936; PMCID: PMC7397641; DOI: 10.1016/j.bbamcr.2016.03.002;

Nurnberg ST, Cheng K, Raiesdana A, Kundu R, Miller CL, Kim JB, Arora K, Carcamo-Oribe I, Xiong Y, Tellakula N, Nanda V, Murthy N, Boisvert WA, Hedin U, Perisic L, Aldi S, Maegdefessel L, Pjanic M, Owens GK, Tallquist MD, Quertermous T. Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap. PLoS Genet. 2015 May; 11(5):e1005155. PMID: 26020946; PMCID: PMC4447275; DOI: 10.1371/journal.pgen.1005155;

Han P, Li W, Lin CH, Yang J, Shang C, Nuernberg ST, Jin KK, Xu W, Lin CY, Lin CJ, Xiong Y, Chien H, Zhou B, Ashley E, Bernstein D, Chen PS, Chen HV, Quertermous T, Chang CP. A long noncoding RNA protects the heart from pathological hypertrophy. Nature. 2014 Oct 02; 514(7520):102-106. PMID: 25119045; PMCID: PMC4184960; DOI: 10.1038/nature13596;

Li W, Lin CY, Shang C, Han P, Xiong Y, Lin CJ, Yang J, Selleri L, Chang CP. Pbx1 activates Fgf10 in the mesenchyme of developing lungs. Genesis. 2014 May; 52(5):399-407. PMID: 24591256; DOI: 10.1002/dvg.22764;

Yang J, Zeini M, Lin CY, Lin CJ, Xiong Y, Shang C, Han P, Li W, Quertermous T, Zhou B, Chang CP. Epicardial calcineurin-NFAT signals through Smad2 to direct coronary smooth muscle cell and arterial wall development. Cardiovasc Res. 2014 Jan 01; 101(1):120-9. PMID: 23946498; PMCID: PMC3868347; DOI: 10.1093/cvr/cvt197;

Pan MG, Xiong Y, Chen F. NFAT gene family in inflammation and cancer. Curr Mol Med. 2013 May; 13(4):543-54. PMID: 22950383; PMCID: PMC3694398; DOI: 10.2174/1566524011313040007;

Xiong Y, Li W, Shang C, Chen RM, Han P, Yang J, Stankunas K, Wu B, Pan M, Zhou B, Longaker MT, Chang CP. Brg1 governs a positive feedback circuit in the hair follicle for tissue regeneration and repair. Dev Cell. 2013 Apr 29; 25(2):169-81. PMID: 23602386; DOI: 10.1016/j.devcel.2013.03.015;

Li W, Xiong Y, Shang C, Twu KY, Hang CT, Yang J, Han P, Lin CY, Lin CJ, Tsai FC, Stankunas K, Meyer T, Bernstein D, Pan M, Chang CP. Brg1 governs distinct pathways to direct multiple aspects of mammalian neural crest cell development. Proc Natl Acad Sci U S A. 2013 Jan 29; 110(5):1738-43. PMID: 23319608; PMCID: PMC3562770; DOI: 10.1073/pnas.1218072110;

Xiong Y, Zhou B, Chang CP. Analysis of the endocardial-to-mesenchymal transformation of heart valve development by collagen gel culture assay. Methods Mol Biol. 2012; 843:101-9. PMID: 22222525; DOI: 10.1007/978-1-61779-523-7_10;

Bajpai R, Chen DA, Rada-Iglesias A, Zhang J, Xiong Y, Helms J, Chang CP, Zhao Y, Swigut T, Wysocka J. CHD7 cooperates with PBAF to control multipotent neural crest formation. Nature. 2010 Feb 18; 463(7283):958-62. PMID: 20130577; PMCID: PMC2890258; DOI: 10.1038/nature08733;

Xiong Y, Singh IN, Hall ED. Tempol protection of spinal cord mitochondria from peroxynitrite-induced oxidative damage. Free Radic Res. 2009 Jun; 43(6):604-12. PMID: 19513907; PMCID: PMC2763567; DOI: 10.1080/10715760902977432;

Xiong Y, Hall ED. Pharmacological evidence for a role of peroxynitrite in the pathophysiology of spinal cord injury. Exp Neurol. 2009 Mar; 216(1):105-14. PMID: 19111721; PMCID: PMC2755491; DOI: 10.1016/j.expneurol.2008.11.025;

Xiong Y, Rabchevsky AG, Hall ED. Role of peroxynitrite in secondary oxidative damage after spinal cord injury. J Neurochem. 2007 Feb; 100(3):639-49. PMID: 17181549; DOI: 10.1111/j.1471-4159.2006.04312.x;

Zhang FY, Li YC, Xiong YQ, Wang GM, Li Q, Song G. [The locus coeruleus modulates the inspiratory inhibition induced by electrical stimulation of the Bötzinger complex]. Sheng Li Xue Bao. 2004 Oct 25; 56(5):639-43. PMID: 15497047

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 36 publications over 17 distinct years, with a maximum of 6 publications in 2025

Bar chart showing 36 publications over 17 distinct years, with a maximum of 6 publications in 2025

Year	Publications
2004	1
2006	1
2008	1
2009	1
2010	1
2012	1
2013	4
2014	2
2015	1
2016	1
2018	4
2019	1
2021	1
2022	2
2023	5
2024	3
2025	6

2011-2012 Stanford University School of Medicine: Pediatric Research Fund Award

2010-2012 American Heart Association: Postdoctoral Fellowship

2009-2013 Stanford University School of Medicine: Oak Foundation Postdoctoral Fellow Award

2005-2007 University of Kentucky Graduate School: Graduate Student Travel Award

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617.414.4291

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