Sulochan Malla, PhD
Postdoctoral Fellow
National Institutes of Health
Laboratory of Genetics and Genomics




Dr. Sulochan Malla is a postdoc fellow in the Laboratory of Genetics and Genomics, National Institute of Health (NIH/NIA). Dr. Malla received his BS degree from SANN International College, Purbanchal University and MS/PhD from Florida Atlantic University. His research interests are on RNA dynamics and their impact on human health and well-being. During his PhD, Dr. Malla studied the molecular basis of RNA damage during oxidative stress and the cellular mechanism of handling oxidatively damaged RNA. RNA oxidation is associated with a large number of human diseases, predominantly age-related neurodegenerative disorders. Mechanistic understanding of RNA oxidation and their quality control process may help to unravel the etiology of many oxidative stress-related human diseases and their therapeutic intervention.

Dr. Malla has served as an editorial board member of JoLS since Jan 2021.

Postdoctoral Associate (previously held)
Boston University Chobanian & Avedisian School of Medicine
Biochemistry & Cell Biology


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Perone I, Ghena N, Wang J, Mackey C, Wan R, Malla S, Gorospe M, Cheng A, Mattson MP. Mitochondrial SIRT3 Deficiency Results in Neuronal Network Hyperexcitability, Accelerates Age-Related Aß Pathology, and Renders Neurons Vulnerable to Aß Toxicity. Neuromolecular Med. 2023 Mar; 25(1):27-39. PMID: 35749057; PMCID: PMC9810471; DOI: 10.1007/s12017-022-08713-2;
     
  2. Khanal M, Timilsina S, Bhatta BP, Bophela K, Coutinho T, Cochran K, Malla S. Pseudomonas uvaldensis sp. nov., a bacterial pathogen causing onion bulb rot. Int J Syst Evol Microbiol. 2022 Apr; 72(4). PMID: 35442877; DOI: 10.1099/ijsem.0.005311;
     
  3. Szaflarski W, Lesniczak-Staszak M, Sowinski M, Ojha S, Aulas A, Dave D, Malla S, Anderson P, Ivanov P, Lyons SM. Early rRNA processing is a stress-dependent regulatory event whose inhibition maintains nucleolar integrity. Nucleic Acids Res. 2022 01 25; 50(2):1033-1051.View Related Profiles. PMID: 34928368; PMCID: PMC8789083; DOI: 10.1093/nar/gkab1231;
     
  4. Malla S, Prasad Bhattarai D, Groza P, Melguizo-Sanchis D, Atanasoai I, Martinez-Gamero C, Román ÁC, Zhu D, Lee DF, Kutter C, Aguilo F. ZFP207 sustains pluripotency by coordinating OCT4 stability, alternative splicing and RNA export. EMBO Rep. 2022 02 03; 23(3):e53191. PMID: 35037361; PMCID: PMC8892232; DOI: 10.15252/embr.202153191;
     
  5. Ojha S, Malla S, Lyons SM. snoRNPs: Functions in Ribosome Biogenesis. Biomolecules. 2020 05 18; 10(5).View Related Profiles. PMID: 32443616; PMCID: PMC7277114; DOI: 10.3390/biom10050783;
     
  6. Malla S, Li Z. Functions of Conserved Domains of Human Polynucleotide Phosphorylase on RNA Oxidation. Insights Biomed Res. 2019; 3(1):62-67. PMID: 32123871; PMCID: PMC7051052; DOI: 10.36959/584/448;
     
  7. Malla S, Melguizo-Sanchis D, Aguilo F. Steering pluripotency and differentiation with N6-methyladenosine RNA modification. Biochim Biophys Acta Gene Regul Mech. 2019 03; 1862(3):394-402. PMID: 30412796; DOI: 10.1016/j.bbagrm.2018.10.013;
     
  8. Li Z, Malla S, Shin B, Li JM. Battle against RNA oxidation: molecular mechanisms for reducing oxidized RNA to protect cells. Wiley Interdiscip Rev RNA. 2014 May-Jun; 5(3):335-46. PMID: 24375979; PMCID: PMC3991771; DOI: 10.1002/wrna.1214;
     

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 8 publications over 5 distinct years, with a maximum of 4 publications in 2022

YearPublications
20131
20181
20191
20201
20224

Contact for Mentoring:

410.454.8414 (fax)
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