Sulochan Malla, PhD
Postdoctoral Fellow
National Institutes of Health
Dept of Laboratory of Genetics and Genomics





Dr. Sulochan Malla is a postdoc fellow in the Laboratory of Genetics and Genomics, National Institute of Health (NIH/NIA). Dr. Malla received his BS degree from SANN International College, Purbanchal University and MS/PhD from Florida Atlantic University. His research interests are on RNA dynamics and their impact on human health and well-being. During his PhD, Dr. Malla studied the molecular basis of RNA damage during oxidative stress and the cellular mechanism of handling oxidatively damaged RNA. RNA oxidation is associated with a large number of human diseases, predominantly age-related neurodegenerative disorders. Mechanistic understanding of RNA oxidation and their quality control process may help to unravel the etiology of many oxidative stress-related human diseases and their therapeutic intervention.

Dr. Malla has served as an editorial board member of JoLS since Jan 2021.

Postdoctoral Associate (previously held)
Boston University School of Medicine
Biochemistry


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Perone I, Ghena N, Wang J, Mackey C, Wan R, Malla S, Gorospe M, Cheng A, Mattson MP. Mitochondrial SIRT3 Deficiency Results in Neuronal Network Hyperexcitability, Accelerates Age-Related Aß Pathology, and Renders Neurons Vulnerable to Aß Toxicity. Neuromolecular Med. 2022 Jun 24. PMID: 35749057
     
  2. Khanal M, Timilsina S, Bhatta BP, Bophela K, Coutinho T, Cochran K, Malla S. Pseudomonas uvaldensis sp. nov., a bacterial pathogen causing onion bulb rot. Int J Syst Evol Microbiol. 2022 Apr; 72(4). PMID: 35442877; DOI: 10.1099/ijsem.0.005311;
     
  3. Szaflarski W, Lesniczak-Staszak M, Sowinski M, Ojha S, Aulas A, Dave D, Malla S, Anderson P, Ivanov P, Lyons SM. Early rRNA processing is a stress-dependent regulatory event whose inhibition maintains nucleolar integrity. Nucleic Acids Res. 2022 01 25; 50(2):1033-1051.View Related Profiles. PMID: 34928368; PMCID: PMC8789083; DOI: 10.1093/nar/gkab1231;
     
  4. Malla S, Prasad Bhattarai D, Groza P, Melguizo-Sanchis D, Atanasoai I, Martinez-Gamero C, Román ÁC, Zhu D, Lee DF, Kutter C, Aguilo F. ZFP207 sustains pluripotency by coordinating OCT4 stability, alternative splicing and RNA export. EMBO Rep. 2022 02 03; 23(3):e53191. PMID: 35037361; PMCID: PMC8892232; DOI: 10.15252/embr.202153191;
     
  5. Ojha S, Malla S, Lyons SM. snoRNPs: Functions in Ribosome Biogenesis. Biomolecules. 2020 05 18; 10(5).View Related Profiles. PMID: 32443616; PMCID: PMC7277114; DOI: 10.3390/biom10050783;
     
  6. Malla S, Li Z. Functions of Conserved Domains of Human Polynucleotide Phosphorylase on RNA Oxidation. Insights Biomed Res. 2019; 3(1):62-67. PMID: 32123871; PMCID: PMC7051052; DOI: 10.36959/584/448;
     
  7. Malla S, Melguizo-Sanchis D, Aguilo F. Steering pluripotency and differentiation with N6-methyladenosine RNA modification. Biochim Biophys Acta Gene Regul Mech. 2019 03; 1862(3):394-402. PMID: 30412796; DOI: 10.1016/j.bbagrm.2018.10.013;
     
  8. Li Z, Malla S, Shin B, Li JM. Battle against RNA oxidation: molecular mechanisms for reducing oxidized RNA to protect cells. Wiley Interdiscip Rev RNA. 2014 May-Jun; 5(3):335-46. PMID: 24375979; PMCID: PMC3991771; DOI: 10.1002/wrna.1214;
     

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 8 publications over 5 distinct years, with a maximum of 4 publications in 2022

YearPublications
20131
20181
20191
20201
20224

Contact for Mentoring:

410.454.8414 (fax)

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