"Eukaryotic Initiation Factor-2B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A guanine nucleotide exchange factor that acts to restore EUKARYOTIC INITIATION FACTOR-2 to its GTP bound form.
Descriptor ID |
D020717
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MeSH Number(s) |
D12.644.360.325.300.050 D12.776.476.325.300.050 D12.776.835.725.868.374
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Concept/Terms |
Eukaryotic Initiation Factor-2B- Eukaryotic Initiation Factor-2B
- Eukaryotic Initiation Factor 2B
- Peptide Initiation Factor EIF-2B
- Peptide Initiation Factor EIF 2B
- EIF2B1
- Eukaryotic Peptide Initiation Factor-2B
- Eukaryotic Peptide Initiation Factor 2B
- EIF-2B
- EIF 2B
- EIF2B
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Below are MeSH descriptors whose meaning is more general than "Eukaryotic Initiation Factor-2B".
Below are MeSH descriptors whose meaning is more specific than "Eukaryotic Initiation Factor-2B".
This graph shows the total number of publications written about "Eukaryotic Initiation Factor-2B" by people in this website by year, and whether "Eukaryotic Initiation Factor-2B" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Eukaryotic Initiation Factor-2B" by people in Profiles.
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Marintchev A, Ito T. eIF2B and the Integrated Stress Response: A Structural and Mechanistic View. Biochemistry. 2020 04 07; 59(13):1299-1308. PMID: 32200625.
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Bogorad AM, Lin KY, Marintchev A. eIF2B Mechanisms of Action and Regulation: A Thermodynamic View. Biochemistry. 2018 03 06; 57(9):1426-1435. PMID: 29425030.
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Bogorad AM, Lin KY, Marintchev A. Novel mechanisms of eIF2B action and regulation by eIF2a phosphorylation. Nucleic Acids Res. 2017 Nov 16; 45(20):11962-11979. PMID: 29036434.
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Bogorad AM, Xia B, Sandor DG, Mamonov AB, Cafarella TR, Jehle S, Vajda S, Kozakov D, Marintchev A. Insights into the architecture of the eIF2Ba/ß/d regulatory subcomplex. Biochemistry. 2014 Jun 3; 53(21):3432-45. PMID: 24811713.
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Maletkovic J, Schiffmann R, Gorospe JR, Gordon ES, Mintz M, Hoffman EP, Alper G, Lynch DR, Singhal BS, Harding C, Amartino H, Brown CM, Chan A, Renaud D, Geraghty M, Jensen L, Senbil N, Kadom N, Nazarian J, Yuanjian Feng, Zuyi Wang, Hartka T, Morizono H, Vanderver A. Genetic and clinical heterogeneity in eIF2B-related disorder. J Child Neurol. 2008 Feb; 23(2):205-15. PMID: 18263758.