"Melanocortins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Peptides derived from pro-opiomelanocortin (POMC) which can stimulate MELANOCYTES or CORTICOTROPHS. Melanocortins include ACTH; ALPHA-MSH; and other peptides such as BETA-MSH and GAMMA-MSH, derived from other fragments of POMC. These peptides act through a variety of MELANOCORTIN RECEPTORS to control different functions including steroidogenesis, energy homeostasis, feeding, and skin pigmentation.
| Descriptor ID |
D053486
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| MeSH Number(s) |
D06.472.699.327.935.531 D06.472.699.631.525.600.531 D12.644.400.400.935.531 D12.644.548.365.935.531 D12.644.548.691.525.690.531 D12.776.641.650.405.935.531
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Melanocortins".
Below are MeSH descriptors whose meaning is more specific than "Melanocortins".
This graph shows the total number of publications written about "Melanocortins" by people in this website by year, and whether "Melanocortins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2015 | 1 | 1 | 2 |
| 2022 | 1 | 0 | 1 |
| 2023 | 1 | 1 | 2 |
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Below are the most recent publications written about "Melanocortins" by people in Profiles.
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Rinne P, Taylor AW, Montero-Melendez T. Editorial: Melanocortins and melanocortin receptors in the regulation of inflammation: mechanisms and novel therapeutic strategies. Front Immunol. 2023; 14:1226886. PMID: 37325641.
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Ng TF, Taylor AW. Stimulating the Melanocortin System in Uveitis and Diabetes Preserves the Structure and Anti-Inflammatory Activity of the Retina. Int J Mol Sci. 2023 Apr 08; 24(8). PMID: 37108092.
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Goit RK, Taylor AW, Lo ACY. The central melanocortin system as a treatment target for obesity and diabetes: A brief overview. Eur J Pharmacol. 2022 Jun 05; 924:174956. PMID: 35430211.
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Lee DJ, Taylor AW. Recovery from experimental autoimmune uveitis promotes induction of antiuveitic inducible Tregs. J Leukoc Biol. 2015 Jun; 97(6):1101-9. PMID: 25877928.
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Iemolo A, Ferragud A, Cottone P, Sabino V. Pituitary Adenylate Cyclase-Activating Peptide in the Central Amygdala Causes Anorexia and Body Weight Loss via the Melanocortin and the TrkB Systems. Neuropsychopharmacology. 2015 Jul; 40(8):1846-55. PMID: 25649277.
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Ghamari-Langroudi M, Vella KR, Srisai D, Sugrue ML, Hollenberg AN, Cone RD. Regulation of thyrotropin-releasing hormone-expressing neurons in paraventricular nucleus of the hypothalamus by signals of adiposity. Mol Endocrinol. 2010 Dec; 24(12):2366-81. PMID: 20943814.
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Hollenberg AN. The role of the thyrotropin-releasing hormone (TRH) neuron as a metabolic sensor. Thyroid. 2008 Feb; 18(2):131-9. PMID: 18279013.