R. Douglas Bruce, MD, MA, MS
Associate Professor
Boston University School of Medicine
Dept of Medicine
General Internal Medicine

MD, University of Texas Southwestern Medical Center

From academics to public/community health, Dr. Bruce has worked to develop and implement research and public health interventions both locally and internationally. Dr. Bruce is a global expert in substance use disorders among people with HIV/hepatitis C and serves as the substance use team lead for the Department of Health and Human Services Antiretroviral Guideline committee. From drug-drug interaction work to ascertain the impact of HIV and HCV therapeutics on methadone/buprenorphine and operations research to improve HIV/HCV and tuberculosis care, he has translated research into the clinical environments to improve outcomes for marginalized populations and reduce health disparities.

A significant portion of Dr. Bruce’s work focused on the impact of addiction on HIV globally. In Tanzania, for example, he had the privilege of working with local leaders to help establish a treatment for opioid use disorders and combat the growing HIV incidence rate among people who inject drugs (42% of people injecting had HIV). In 2010, he worked to establish, train, and mentor clinical staff in preparation for starting the first public methadone program in continental sub-Sahara Africa, which started dosing in February 2011. The program has grown from one clinic to several, with thousands in treatment and clinical programs at the intersection of addiction and HIV and tuberculosis. In addition to the work in Tanzania, he has provided technical assistance to the CDC, United Nations, USAID, and non-governmental organizations to address HIV and substance use epidemics globally.

Dr. Bruce transitioned out of his research role at Yale and took the Chief of Medicine position at Cornell Scott-Hill Health Center (CSHHC) with the goal of transforming healthcare in the New Haven community. Over the next 7 years he had the privilege of helping to transform the largest health center in New Haven with a focus on quality and value based care which resulted in significant improvements in the delivery of clinical care, improvements in quality of care, and cost savings for CT Medicaid and the community. At the time of Dr. Bruce’s departure, the health center was poised to assume operational control of the Internal Medicine and OB/GYN ambulatory practices and outpatient residency training of Yale New Haven Health in October 2020. This will grow the health center’s relationship with the Yale School of Medicine as faculty will now teach within a health center context and will add over 10,000 patients and over 150 residents into the health center community.

In September 2020, Dr. Bruce moved to Boston to join Boston University School of Medicine and Boston Medical Center to continue practice transformation, innovation and quality improvement within a safety net organization’s large academic medical practice.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Mandyam VC, Bruce RD. Chronic Pain and Opioid Use in Older People With HIV. Top Antivir Med. 2022 Dec-Jan; 29(5):419-422.View Related Profiles. PMID: 35191657; PMCID: PMC8862752
  2. Bonner R, Stewart J, Upadhyay A, Bruce RD, Taylor JL. A Primary Care Intervention to Increase HIV Pre-Exposure Prophylaxis (PrEP) Uptake in Patients with Syphilis. J Int Assoc Provid AIDS Care. 2022 Jan-Dec; 21:23259582211073393.View Related Profiles. PMID: 35001723; PMCID: PMC8753072; DOI: 10.1177/23259582211073393;
  3. Minja LT, Hella J, Mbwambo J, Nyandindi C, Omary US, Levira F, Mpagama S, Shimwela M, Okuma J, Gagneux S, Bruce RD, Reither K. High burden of tuberculosis infection and disease among people receiving medication-assisted treatment for substance use disorder in Tanzania. PLoS One. 2021; 16(4):e0250038. PMID: 33914753; PMCID: PMC8084249; DOI: 10.1371/journal.pone.0250038;
  4. Kurth AE, Cherutich P, Conover R, Chhun N, Bruce RD, Lambdin BH. The Opioid Epidemic in Africa And Its Impact. Curr Addict Rep. 2018 Dec; 5(4):428-453. PMID: 32494564; PMCID: PMC7269163; DOI: 10.1007/s40429-018-0232-9;
  5. Bruce RD. Opioid addiction, opioid addiction treatment, and HIV infection. Top Antivir Med. 2018 Sep; 26(3):89-92. PMID: 30384332; PMCID: PMC6291298
  6. Bruce RD, Merlin J, Lum PJ, Ahmed E, Alexander C, Corbett AH, Foley K, Leonard K, Treisman GJ, Selwyn P. 2017 HIVMA of IDSA Clinical Practice Guideline for the Management of Chronic Pain in Patients Living With HIV. Clin Infect Dis. 2017 Oct 30; 65(10):e1-e37. PMID: 29020263; PMCID: PMC5848240; DOI: 10.1093/cid/cix636;
  7. Bruce RD, Merlin J, Lum PJ, Ahmed E, Alexander C, Corbett AH, Foley K, Leonard K, Treisman GJ, Selwyn P. 2017 HIV Medicine Association of Infectious Diseases Society of America Clinical Practice Guideline for the Management of Chronic Pain in Patients Living With Human Immunodeficiency Virus. Clin Infect Dis. 2017 Oct 30; 65(10):1601-1606. PMID: 29091230; PMCID: PMC5850004; DOI: 10.1093/cid/cix848;
  8. Harris DA, Mainardi A, Iyamu O, Rosenthal MS, Bruce RD, Pisani MA, Redlich CA. Improving the asthma disparity gap with legal advocacy? A qualitative study of patient-identified challenges to improve social and environmental factors that contribute to poorly controlled asthma. J Asthma. 2018 08; 55(8):924-932. PMID: 28872933; DOI: 10.1080/02770903.2017.1373393;
  9. Gibson BA, Morano JP, Walton MR, Marcus R, Zelenev A, Bruce RD, Altice FL. Innovative Program Delivery and Determinants of Frequent Visitation to a Mobile Medical Clinic in an Urban Setting. J Health Care Poor Underserved. 2017; 28(2):643-662. PMID: 28529215; DOI: 10.1353/hpu.2017.0065;
  10. Beckman AL, Bilinski A, Boyko R, Camp GM, Wall AT, Lim JK, Wang EA, Bruce RD, Gonsalves GS. New Hepatitis C Drugs Are Very Costly And Unavailable To Many State Prisoners. Health Aff (Millwood). 2016 10 01; 35(10):1893-1901. PMID: 27702964
Showing 10 of 91 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 91 publications over 18 distinct years, with a maximum of 16 publications in 2013


2008-2010 Yale Center for Clinical Investigation: Clinical and Translational Science Award (CTSA) Scholar
1993 Houston Baptist University: Cum Laude
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801 Massachusetts Avenue, 2nd floor
Boston MA 02118
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