Phillip J. Stone, PhD
Emeritus Professor
Boston University School of Medicine
Dept of Biochemistry

PhD, Temple University
MA, University of Pennsylvania



I began in 1971 as a postdoc for Marrott Sinex, the Chair of Biochemistry at that time with a second postdoc in Carl Franzblau’s lab beginning in 1973, followed by a Young Investigator Award, NHLBI. Besides my current responsibilities as Assistant Dean of Admissions for the Medical School, I am department representative on the Institutional Animal Care and Use Committee. I also teach in MD512/OH751 (Dental Biochemistry) the myoglobin and hemoglobin section and supervise a student presented case on sickle cell disease in dental medicine.

Assistant Dean
Boston University School of Medicine
Admissions


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences




Initial Assessment of Elastese Inhibitors from SolMap Pharmaceuticals for Treatment of Emphysema
06/01/2007 - 05/31/2009 (PI)
SolMap

Functional Repair of Elastin with Recomb. Tropoelastin
09/25/2002 - 08/31/2006 (PI)
NIH/National Institute of Biomedical Imaging & Bioengineering
5 R21 EB00988 03

Mechanisms of Perturbation of Pulmonary Lysyl Oxidase by Cigarette Smoke
08/01/2002 - 01/31/2006 (Co-PI)
PI: Wande Li, MD
Philip Morris Inc

Lung Connective Tissue: Responses to Injury and Repair
12/01/1996 - 11/30/2001 (Co-PI)
NIH/National Heart, Lung, and Blood Institute
5 P01 HL46902 10




Yr Title Project-Sub Proj Pubs
2004 Functional Repair of Elastin with Recomb. Tropoelastin 5R21EB000988-03 3
2003 Functional Repair of Elastin with Recomb. Tropoelastin 5R21EB000988-02 3
2002 Functional Repair of Elastin with Recomb. Tropoelastin 1R21EB000988-01 3
2001 EXTRACELLULAR REPAIR OF LUNG ELASTIC FIBERS 5P01HL046902-10-3 80
2001 TROPOELASTIN REQUIREMENT FOR EXTRACELLULAR REPAIR OF LUNG ELASTIN FIBERS 3P41RR010888-05S1-69 236
2000 TROPOELASTIN REQUIREMENT FOR EXTRACELLULAR REPAIR OF LUNG ELASTIN FIBERS 5P41RR010888-05-69 236
2000 EXTRACELLULAR REPAIR OF LUNG ELASTIC FIBERS 5P01HL046902-09-3 80
1999 TROPOELASTIN REQUIREMENT FOR EXTRACELLULAR REPAIR OF LUNG ELASTIN FIBERS 5P41RR010888-04-69 236
1999 EXTRACELLULAR REPAIR OF LUNG ELASTIC FIBERS 5P01HL046902-08-3 80
1998 EXTRACELLULAR REPAIR OF LUNG ELASTIC FIBERS 2P01HL046902-07-3 80
Showing 10 of 17 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Seidl SE, Pessolano LG, Bishop CA, Best M, Rich CB, Stone PJ, Schreiber BM. Toll-like receptor 2 activation and serum amyloid A regulate smooth muscle cell extracellular matrix. PLoS One. 2017; 12(3):e0171711.View Related Profiles. PMID: 28257481; DOI: 10.1371/journal.pone.0171711;.
     
  2. Pessolano LG, Sullivan CP, Seidl SE, Rich CB, Liscum L, Stone PJ, Sipe JD, Schreiber BM. Trafficking of endogenous smooth muscle cell cholesterol: a role for serum amyloid A and interleukin-1ß. Arterioscler Thromb Vasc Biol. 2012 Nov; 32(11):2741-50.View Related Profiles. PMID: 22995521; PMCID: PMC3559242; DOI: 10.1161/ATVBAHA.112.300243;.
     
  3. Isenberg BC, Backman DE, Kinahan ME, Jesudason R, Suki B, Stone PJ, Davis EC, Wong JY. Micropatterned cell sheets with defined cell and extracellular matrix orientation exhibit anisotropic mechanical properties. J Biomech. 2012 Mar 15; 45(5):756-61. PMID: 22177672; DOI: 10.1016/j.jbiomech.2011.11.015;.
     
  4. Guarnieri F, Spencer JL, Lucey EC, Nugent MA, Stone PJ. A human surfactant peptide-elastase inhibitor construct as a treatment for emphysema. Proc Natl Acad Sci U S A. 2010 Jun 8; 107(23):10661-6.View Related Profiles. PMID: 20534582; PMCID: PMC2890802; DOI: 10.1073/pnas.1001349107;.
     
  5. Zhao Y, Chen L, Gao S, Toselli P, Stone P, Li W. The critical role of the cellular thiol homeostasis in cadmium perturbation of the lung extracellular matrix. Toxicology. 2010 Jan 12; 267(1-3):60-9.View Related Profiles. PMID: 19879314; PMCID: PMC2814991; DOI: 10.1016/j.tox.2009.10.021;.
     
  6. Ritter MC, Jesudason R, Majumdar A, Stamenovic D, Buczek-Thomas JA, Stone PJ, Nugent MA, Suki B. A zipper network model of the failure mechanics of extracellular matrices. Proc Natl Acad Sci U S A. 2009 Jan 27; 106(4):1081-6.View Related Profiles. PMID: 19144920; PMCID: PMC2633546; DOI: 10.1073/pnas.0808414106;.
     
  7. Jesudason RE, Allen PG, Parameswaran H, Suki B, Stone PJ. American Thoracic Society 2009 International Conference. Interaction between Elastase Activity and Mechanical Forces in Lung Tissue Strips. San Diego. 2009. View Publication
     
  8. Seidl S, Rich CB, Sullivan CP, Stone PJ, Schreiber BM. Arteriosclerosis Thrombosis and Vascular Biology. Serum Amyloid A Downregulates Elastin and Upregulates Matrix Metalloproteinase-9 Gene Expression in Smooth Muscle Cells. 2009.
     
  9. Black LD, Allen PG, Morris SM, Stone PJ, Suki B. Mechanical and failure properties of extracellular matrix sheets as a function of structural protein composition. Biophys J. 2008 Mar 1; 94(5):1916-29. PMID: 17993498; PMCID: PMC2242735.
     
  10. Gao S, Zhao Y, Kong L, Toselli P, Chou IN, Stone P, Li W. Cloning and characterization of the rat lysyl oxidase gene promoter: identification of core promoter elements and functional nuclear factor I-binding sites. J Biol Chem. 2007 Aug 31; 282(35):25322-37.View Related Profiles. PMID: 17597074.
     
Showing 10 of 122 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 112 publications over 32 distinct years, with a maximum of 9 publications in 1983

YearPublications
19812
19823
19839
19842
19856
19866
19874
19884
19893
19906
19916
19925
19935
19942
19957
19962
19974
19983
19992
20002
20011
20022
20031
20046
20054
20063
20074
20094
20101
20111
20121
20171
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72 E. Concord St Silvio Conte (K)
Boston MA 02118
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