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PhD, Boston University
MS, Tufts University

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Publications

BU Research
NIH RePORTER Research

Endothelin and Angiotensin Receptor Signaling in Pulmonary Hypertension
12/01/1981 - 11/30/2014 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL025776-28

Pre- and Postdoctoral Training in Biochemistry of Aging
09/01/1985 - 04/30/2013 (PI)
NIH/National Institute on Aging
3T32AG000115-25S1

Title

Yr	Title	Project-Sub Proj	Pubs
2013	Endothelin and Angiotensin Receptor Signaling in Pulmonary Hypertension	5R01HL025776-28	53
2012	Pre- and Postdoctoral Training in Biochemistry of Aging	3T32AG000115-25S1	20
2012	Endothelin and Angiotensin Receptor Signaling in Pulmonary Hypertension	5R01HL025776-27	53
2011	PROTEOMIC CHANGES IN MUSCLE CELLS WITH PULMONARY HYPERTENSION	5P41RR010888-15-5162	259
2011	Pre- and Postdoctoral Training in Biochemistry of Aging	5T32AG000115-25	20
2011	Endothelin and Angiotensin Receptor Signaling in Pulmonary Hypertension	5R01HL025776-26	53
2010	Pre- and Postdoctoral Training in Biochemistry of Aging	5T32AG000115-24	20
2010	Endothelin and Angiotensin Receptor Signaling in Pulmonary Hypertension	3R01HL025776-25S1	53
2010	Endothelin and Angiotensin Receptor Signaling in Pulmonary Hypertension	5R01HL025776-25	53
2009	Pre- and Postdoctoral Training in Biochemistry of Aging	5T32AG000115-23	20

Showing 10 of 60 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Ghosh S, Gupta M, Xu W, Mavrakis DA, Janocha AJ, Comhair SA, Haque MM, Stuehr DJ, Yu J, Polgar P, Naga Prasad SV, Erzurum SC. Phosphorylation inactivation of endothelial nitric oxide synthesis in pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol. 2016 Jun 01; 310(11):L1199-205. PMID: 27130529; PMCID: PMC4935470; DOI: 10.1152/ajplung.00092.2016;

Wilson JL, Yu J, Taylor L, Polgar P. Hyperplastic Growth of Pulmonary Artery Smooth Muscle Cells from Subjects with Pulmonary Arterial Hypertension Is Activated through JNK and p38 MAPK. PLoS One. 2015; 10(4):e0123662.View Related Profiles.

Wilson, Jamie
Yu, Jun
Taylor, Linda
Polgar, Peter

PMID: 25905460; PMCID: PMC4408087; DOI: 10.1371/journal.pone.0123662;

Yu J, Wilson J, Taylor L, Polgar P. DNA microarray and signal transduction analysis in pulmonary artery smooth muscle cells from heritable and idiopathic pulmonary arterial hypertension subjects. J Cell Biochem. 2015 Mar; 116(3):386-97.View Related Profiles.

Wilson, Jamie
Yu, Jun
Taylor, Linda
Polgar, Peter

PMID: 25290246; PMCID: PMC4391824; DOI: 10.1002/jcb.24987;

Yao C, Yu J, Taylor L, Polgar P, McComb ME, Costello CE. Protein Expression by Human Pulmonary Artery Smooth Muscle Cells Containing a BMPR2 Mutation and the Action of ET-1 as Determined by Proteomic Mass Spectrometry. Int J Mass Spectrom. 2015 Feb 15; 378:347-359.View Related Profiles.

Costello, Catherine
Yao, Chunxiang
Taylor, Linda
McComb, Mark
Polgar, Peter

PMID: 25866469; PMCID: PMC4387548; DOI: 10.1016/j.ijms.2014.10.006;

Wilson JL, Rupasinghe C, Usheva A, Warburton R, Kaplan C, Taylor L, Hill N, Mierke DF, Polgar P. Modulating the dysregulated migration of pulmonary arterial hypertensive smooth muscle cells with motif mimicking cell permeable peptides. Curr Top Pept Protein Res. 2015; 16:1-17.View Related Profiles.

Wilson, Jamie
Polgar, Peter

PMID: 27274622; PMCID: PMC4888800

Yu J, Rupasinghe C, Wilson JL, Taylor L, Rahimi N, Mierke D, Polgar P. Targeting receptor tyrosine kinases and their downstream signaling with cell-penetrating peptides in human pulmonary artery smooth muscle and endothelial cells. Chem Biol Drug Des. 2015 May; 85(5):586-97.View Related Profiles.

Wilson, Jamie
Yu, Jun
Taylor, Linda
Rahimi, Nader
Polgar, Peter

PMID: 25298192; PMCID: PMC4390552; DOI: 10.1111/cbdd.12446;

Green DS, Rupasinghe C, Warburton R, Wilson JL, Sallum CO, Taylor L, Yatawara A, Mierke D, Polgar P, Hill N. A cell permeable peptide targeting the intracellular loop 2 of endothelin B receptor reduces pulmonary hypertension in a hypoxic rat model. PLoS One. 2013; 8(11):e81309.View Related Profiles.

Sallum, Christine
Green, Daniel
Wilson, Jamie
Taylor, Linda
Polgar, Peter

PMID: 24312288; PMCID: PMC3842336; DOI: 10.1371/journal.pone.0081309;

Yatawara A, Wilson JL, Taylor L, Polgar P, Mierke DF. C-terminus of ETA/ETB receptors regulate endothelin-1 signal transmission. J Pept Sci. 2013 Apr; 19(4):257-62.View Related Profiles.

Wilson, Jamie
Taylor, Linda
Polgar, Peter

PMID: 23436727; PMCID: PMC3770155; DOI: 10.1002/psc.2499;

Yu J, Taylor L, Wilson J, Comhair S, Erzurum S, Polgar P. Altered expression and signal transduction of endothelin-1 receptors in heritable and idiopathic pulmonary arterial hypertension. J Cell Physiol. 2013 Feb; 228(2):322-9.View Related Profiles.

Wilson, Jamie
Yu, Jun
Taylor, Linda
Polgar, Peter

PMID: 22688668; PMCID: PMC3496420; DOI: 10.1002/jcp.24132;

Kao PF, Banigan MG, Vanderburg CR, McKee AC, Polgar PR, Seshadri S, Delalle I. Increased expression of TrkB and Capzb2 accompanies preserved cognitive status in early Alzheimer disease pathology. J Neuropathol Exp Neurol. 2012 Jul; 71(7):654-64.View Related Profiles.

McKee, Ann
Delalle, Ivana
Polgar, Peter
Seshadri, Sudha

PMID: 22710966; PMCID: PMC3398703; DOI: 10.1097/NEN.0b013e31825d06b7;

Showing 10 of 76 results. Show More

Sallum CO, Wilson JL, Rupasinghe C, Berg E, Yu J, Green DS, Taylor L, Mierke D, Polgar P. Enhancing and limiting endothelin-1 signaling with a cell-penetrating peptide mimicking the third intracellular loop of the ETB receptor. Chem Biol Drug Des. 2012 Sep; 80(3):374-81.View Related Profiles.

Sallum, Christine
Green, Daniel
Wilson, Jamie
Yu, Jun
Taylor, Linda
Polgar, Peter

PMID: 22553998; PMCID: PMC3496424; DOI: 10.1111/j.1747-0285.2012.01405.x;

Yu J, Taylor L, Rich C, Toselli P, Stone P, Green D, Warburton R, Hill N, Goldstein R, Polgar P. Transgenic expression of an altered angiotensin type I AT1 receptor resulting in marked modulation of vascular type I collagen. J Cell Physiol. 2012 May; 227(5):2013-21.View Related Profiles.

Green, Daniel
Yu, Jun
Taylor, Linda
Toselli, Paul
Polgar, Peter
Goldstein, Ronald

PMID: 21751211; PMCID: PMC3247653; DOI: 10.1002/jcp.22929;

Wilson JL, Taylor L, Polgar P. Endothelin-1 activation of ETB receptors leads to a reduced cellular proliferative rate and an increased cellular footprint. Exp Cell Res. 2012 Jun 10; 318(10):1125-33.View Related Profiles.

Wilson, Jamie
Taylor, Linda
Polgar, Peter

PMID: 22504006; PMCID: PMC3496421; DOI: 10.1016/j.yexcr.2012.03.029;

Erzurum S, Rounds SI, Stevens T, Aldred M, Aliotta J, Archer SL, Asosingh K, Balaban R, Bauer N, Bhattacharya J, Bogaard H, Choudhary G, Dorn GW, Dweik R, Fagan K, Fallon M, Finkel T, Geraci M, Gladwin MT, Hassoun PM, Humbert M, Kaminski N, Kawut SM, Loscalzo J, McDonald D, McMurtry IF, Newman J, Nicolls M, Rabinovitch M, Shizuru J, Oka M, Polgar P, Rodman D, Schumacker P, Stenmark K, Tuder R, Voelkel N, Sullivan E, Weinshilboum R, Yoder MC, Zhao Y, Gail D, Moore TM. Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report. Am J Respir Crit Care Med. 2010 Dec 15; 182(12):1554-62. PMID: 20833821; PMCID: PMC3029941; DOI: 10.1164/rccm.201006-0869WS;

Yu J, Taylor L, Mierke D, Berg E, Shia M, Fishman J, Sallum C, Polgar P. Limiting angiotensin II signaling with a cell-penetrating peptide mimicking the second intracellular loop of the angiotensin II type-I receptor. Chem Biol Drug Des. 2010 Jul; 76(1):70-6.View Related Profiles.

Sallum, Christine
Taylor, Linda
Polgar, Peter

PMID: 20492449; PMCID: PMC2994263; DOI: 10.1111/j.1747-0285.2010.00985.x;

Huang Z, Yu J, Toselli P, Bhawan J, Sudireddy V, Taylor L, Polgar P. Angiotensin II type 1 and bradykinin B2 receptors expressed in early stage epithelial cells derived from human embryonic stem cells. J Cell Physiol. 2007 Jun; 211(3):816-25.View Related Profiles.

Bhawan, Jag
Yu, Jun
Taylor, Linda
Toselli, Paul
Polgar, Peter

PMID: 17299793

Yu J, Lubinsky D, Tsomaia N, Huang Z, Taylor L, Mierke D, Navarro J, Miraz O, Polgar P. Activation of ERK, JNK, Akt, and G-protein coupled signaling by hybrid angiotensin II AT1/bradykinin B2 receptors expressed in HEK-293 cells. J Cell Biochem. 2007 May 1; 101(1):192-204.View Related Profiles.

Yu, Jun
Taylor, Linda
Polgar, Peter

PMID: 17212359

Huang Z, Taylor L, Liu B, Yu J, Polgar P. Modulation by bradykinin of angiotensin type 1 receptor-evoked RhoA activation of connective tissue growth factor expression in human lung fibroblasts. Am J Physiol Lung Cell Mol Physiol. 2006 Jun; 290(6):L1291-9.View Related Profiles.

Liu, Bing
Yu, Jun
Taylor, Linda
Polgar, Peter

PMID: 16684954

Liu B, Yu J, Taylor L, Zhou X, Polgar P. Microarray and phosphokinase screenings leading to studies on ERK and JNK regulation of connective tissue growth factor expression by angiotensin II 1a and bradykinin B2 receptors in Rat1 fibroblasts. J Cell Biochem. 2006 Apr 1; 97(5):1104-20.View Related Profiles.

Liu, Bing
Yu, Jun
Taylor, Linda
Polgar, Peter

PMID: 16294326

Yu J, Polgar P, Lubinsky D, Gupta M, Wang L, Mierke D, Taylor L. Coulombic and hydrophobic interactions in the first intracellular loop are vital for bradykinin B2 receptor ligand binding and consequent signal transduction. Biochemistry. 2005 Apr 12; 44(14):5295-306.View Related Profiles.

Yu, Jun
Taylor, Linda
Polgar, Peter

PMID: 15807523

Piserchio A, Zelesky V, Yu J, Taylor L, Polgar P, Mierke DF. Bradykinin B2 receptor signaling: structural and functional characterization of the C-terminus. Biopolymers. 2005; 80(2-3):367-73.View Related Profiles.