Nicole Siegel, MD
Clinical Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Ophthalmology & Vision Sciences

MD, New York University School of Medicine
BA, Dartmouth College



Nicole Siegel, MD, an Assistant Professor of Ophthalmology at the Chobanian and Avedisian School of Medicine, is the Vice Chair of Education and the Program Director of the Ophthalmology Residency. Formerly, she served as the Associate Program Director and the Director of Medical Student Education in the Department of Ophthalmology for the Chobanian and Avedisian School of Medicine. She is a vitreoretinal surgeon with her academic practice at Chobanian and Avedisian School of Medicine, as part of the Boston University Eye Associates (BUEA). She sees patients at Boston Medical Center and at the BUEA Brockton office. Dr. Siegel's clinical and surgical interests include diabetic retinopathy, age-related macular degeneration, retinal vein occlusions, intraocular inflammation, retinal detachments, macular holes and membranes, dislocated intraocular lenses.

Dr. Siegel completed both her Ophthalmology residency, serving as chief resident, and her two-year vitreoretinal Surgery fellowship at Boston Medical Center. Prior to that, Dr. Siegel graduated from the New York University School of Medicine. During her time in medical school she spent time doing research and was the vice president of the NYU chapter of Unite For Sight.

Dr. Siegel's research interests include evaluating patient satisfaction for sedation used in ophthalmic surgery, intraocular inflammation, the diagnostic yield of aqueous and vitreous biomarkers and on-going multi-disciplinary projects. In addition to invited oral presentations and authoring manuscripts, case reports and book chapters, Dr. Siegel is a member of the American Academy of Ophthalmology, the American Society of Retina Specialists, Women in Retina, The Association for Research in Vision and Ophthalmology, the Massachusetts Medical Society, and the New England Ophthalmological Society.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Subramanian ML, Sampani K, Ness S, Tuz-Zahra F, Alluri S, Chen X, Siegel NH, Aytan N, Xia W, Tripodis Y, Alosco ML, Stein TD. Biomarkers for Alzheimer's disease are upregulated in patients with diabetic retinopathy. J Alzheimers Dis. 2025 Sep 22; 13872877251378759.View Related Profiles. PMID: 40982223; DOI: 10.1177/13872877251378759;
     
  2. Shoushtari SI, Liaw E, Alluri S, Sheikh Z, Kumar S, Huynh C, Schmidt IM, Ness S, Chen X, Siegel NH, Waikar SS, Stein TD, Lu W, Subramanian ML. The association between SLIT2 in human vitreous humor and plasma and neurocognitive test scores. J Alzheimers Dis. 2025 Sep 03; 13872877251374287.View Related Profiles. PMID: 40899951; DOI: 10.1177/13872877251374287;
     
  3. Gao A, Tuz-Zahra F, Vig V, Zeng R, Tripodis Y, Stein TD, Alosco ML, Ness S, Chen X, Siegel N, Subramanian ML. The Association between Retinal Vascular Occlusions and Dementia: A UK Biobank Retrospective Longitudinal Study. Ophthalmol Retina. 2025 Aug 16.View Related Profiles. PMID: 40825393; DOI: 10.1016/j.oret.2025.08.010;
     
  4. Ness S, Sampani K, Tuz-Zahra F, Aytan N, Alluri S, Fiorello MG, Chen X, Siegel NH, Alosco ML, Xia W, Tripodis Y, Stein TD, Subramanian ML. Glial fibrillary acidic protein in plasma and intraocular fluids and the correlation with cognitive function in patients with vitreoretinal disease. Sci Rep. 2025 Aug 06; 15(1):28720.View Related Profiles. PMID: 40770000; PMCID: PMC12328637; DOI: 10.1038/s41598-025-13260-4;
     
  5. Shoushtari SI, Liaw E, Alluri S, Sheikh Z, Kumar S, Huynh C, Schmidt IM, Ness S, Chen X, Siegel NH, Waikar SS, Stein TD, Lu W, Subramanian ML. The Association Between SLIT2 in Human Vitreous Humor and Plasma and Neurocognitive Test Scores. bioRxiv. 2025 Jul 02.View Related Profiles. PMID: 40631316; PMCID: PMC12236819; DOI: 10.1101/2025.05.03.652072;
     
  6. Prasad M, Goodman D, Osathanugrah P, Sanjiv N, Chen X, Ness S, Siegel NH, Subramanian ML. Impact of race and socioeconomic disparities on the short-term efficacy of bevacizumab for macular edema secondary to retinal vein occlusion. J Natl Med Assoc. 2025 Apr; 117(2):132-139.View Related Profiles. PMID: 40340111
     
  7. Prasad M, Goodman D, Gutta S, Sheikh Z, Cabral HJ, Shunyakova J, Sanjiv N, Curley C, Yarala RR, Tsai L, Siegel NH, Chen X, Poulaki V, Alosco ML, Stein TD, Ness S, Subramanian ML. Associations Between Retinal Vascular Occlusions and Dementia. Healthcare (Basel). 2024 Nov 26; 12(23).View Related Profiles. PMID: 39684995; PMCID: PMC11641452; DOI: 10.3390/healthcare12232371;
     
  8. Sampani K, Ness S, Tuz-Zahra F, Aytan N, Spurlock EE, Alluri S, Chen X, Siegel NH, Alosco ML, Xia W, Tripodis Y, Stein TD, Subramanian ML. Neurodegenerative biomarkers in different chambers of the eye relative to plasma: an agreement validation study. Alzheimers Res Ther. 2024 Aug 26; 16(1):192.View Related Profiles. PMID: 39187891; PMCID: PMC11346268; DOI: 10.1186/s13195-024-01556-y;
     
  9. Prasad M, Goodman D, Xu J, Gutta S, Zubieta D, Alluri S, Siegel NH, Peeler CE, Lee HJ, Cabral HJ, Subramanian ML. Long-Term Satisfaction of Oral Sedation versus Standard-of-Care Intravenous Sedation for Ocular Surgery. Clin Ophthalmol. 2024; 18:735-742.View Related Profiles. PMID: 38476357; PMCID: PMC10929550; DOI: 10.2147/OPTH.S444999;
     
  10. Dia M, Davoudi S, Sanayei N, Martin DC, Albrecht MM, Ness S, Subramanian M, Siegel N, Chen X. Demographic and socioeconomic disparities in the hybrid ophthalmology telemedicine model. J Telemed Telecare. 2025 Jun; 31(5):697-704.View Related Profiles. PMID: 37960873
     
Showing 10 of 54 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 53 publications over 15 distinct years, with a maximum of 10 publications in 2021

YearPublications
20091
20101
20112
20123
20131
20141
20164
20171
20193
20203
202110
20226
20238
20243
20256


2019-2020 Boston University Medical Center: Women's Leadership Program, Participant
2019 Boston University Medical Center, Department of Ophthalmology: Outstanding Clinical Instructor
2010-2011 Boston University Medical Center: Chief Resident- Department of Ophthalmology
2004 New York University School of Medicine: National Deans List for Academic Honors
2003 Dartmouth College: Cum Laude Honors
2003 Dartmouth College: National Society of Collegiate Scholars

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